LOCUS       BGC0001476             17700 bp    DNA     linear   BCT 07-APR-2018
DEFINITION  Streptomyces sp. strain ID38640 pseudouridimycin biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0001476
VERSION     BGC0001476
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 01:55:06
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17700
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..17700
                     /db_xref="taxon:1931"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp."
                     /strain="ID38640"
     misc_feature    1..17700
                     /note="pseudouridimycin biosynthetic gene cluster"
     protocluster    1..17700
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[9443:10472]"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or ToyB or TunD or
                     pur6 or pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9444..10472
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or ToyB or TunD or
                     pur6 or pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
     protocluster    1..17700
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3575:4832]"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or fom1 or bcpB or
                     frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      3576..4832
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or fom1 or bcpB or
                     frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="2"
     cand_cluster    1..17700
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(LmbU or Neocarzinostat or fom1 or bcpB
                     or frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /detection_rules="(LipM or LipV or LipU or ToyB or TunD or
                     pur6 or pur10 or nikJ or nikO or truD)"
                     /kind="neighbouring"
                     /product="other"
                     /product="nucleoside"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..17700
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001476"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17700
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="other"
                     /product="nucleoside"
                     /region_number="1"
                     /rules="(LmbU or Neocarzinostat or fom1 or bcpB or frbD or
                     mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)"
                     /rules="(LipM or LipV or LipU or ToyB or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(220..624)
                     /gene="pumA"
     CDS             complement(220..624)
                     /codon_start=1
                     /gene="pumA"
                     /product="pumA"
                     /protein_id="AVT42371.1"
                     /transl_table=11
                     /translation="MTGSSPMSPHHERLRSFTINCDGETLSCAAIEPPRTPTSPRAPLA
                     AAVLHGAGTGDKTRHTALLTDFAARGHHALACDFSGHTSRSRFTRLVHPGTDHRLGSWF
                     AENSGPRGRFVDTVLRGTPYECTPPLPRPG"
     gene            complement(621..1811)
                     /gene="pumB"
     CDS             complement(621..1811)
                     /codon_start=1
                     /gene="pumB"
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 59.1; E-value: 4.9e-18)"
                     /gene_kind="transport"
                     /product="putative transporter"
                     /protein_id="AVT42372.1"
                     /transl_table=11
                     /translation="MDRYLRAGRLATFAYFTLNGFLMGMWIVHIPGIEHRAGISHALLG
                     WLLLLLGAGAFAGMQATGPLTDRFGSRTVVPLSAALCSAALVLPGLAANAWTLGAALLV
                     LGVGNGCLDVSMNAHAVQVEQGYRRPVMSAFHAAFSLGGVLASLVGARTLGWHWSPVTT
                     LGTVALVGLAVTAFAAPALLRPAEARRPVEAAVAVVNAPRRTPRHIWALATLALMIMLS
                     EGVANDWSALHLRNVLDAPAATAALAYGSFATTMTLGRLLADRVAARFGPVAILRHGAS
                     VAALGLTAAALSPWIPLALIGWAVFGAGLSGCVPQLFSAAGHTDQGAAGTNVSRVAGLG
                     YLGMLAGPAVIGPMTHVLPLNLTLFLPVLCCVIAAATAAIVRPSRHAPARLETEAV"
     gene            1884..2642
                     /gene="pumC"
     CDS             1884..2642
                     /codon_start=1
                     /gene="pumC"
                     /product="DeoR family transcriptional regulator"
                     /protein_id="AVT42373.1"
                     /transl_table=11
                     /translation="MVSTDRLRQITEAVREAGRVGVAELAALTGASEMTIRRDLEVLAD
                     QGVLERYRGGARSLLLRGEEPPFALRAQEGTAVKRRIAAEVADLIADGESVVLDSGTTC
                     LEVARALEHRRLTVAPLSLHAVNALSGAPNVTLLVPGGRPRSGELALTGPLTQASLAAL
                     RFDTAVISCCGLTAANGLTAYDLDDAAVKRTAIASARRVIAVTESAKLSRTALAFVAPA
                     SALHALVTDEAAPEDETGAITAAGVTVRKV"
     gene            2647..3249
                     /gene="pumD"
     CDS             2647..3249
                     /codon_start=1
                     /gene="pumD"
                     /product="HAD family hydrolase"
                     /protein_id="AVT42386.1"
                     /transl_table=11
                     /translation="MTGTVLFDLFGVIARHQSTEGKNRLTRTAGVAGPAFWDAYWELRP
                     PYDRGEVNGPGYWRQVADAIGVRFDDHRIADLVEADIASWSAVDDTMVALIEELTATGR
                     HMGLLSNIPEELASHYEAHHAWLKHFPVRAFSCRMGHAKPERAAYEWCQHALRTEPDRI
                     LFVDDRADNVRAAEELGMQGHLFTTPDRLRQALSQWT"
     gene            complement(3576..4832)
                     /gene="pumE"
     CDS             complement(3576..4832)
                     /codon_start=1
                     /gene="pumE"
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     CaiA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 163.6;
                     E-value: 9.7e-50)"
                     /gene_kind="biosynthetic"
                     /product="flavin-dependent oxidoreductase"
                     /protein_id="AVT42374.1"
                     /sec_met_domain="CaiA (E-value: 5e-147, bitscore: 479.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.6e-11, bitscore:
                     34.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-12, bitscore:
                     38.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-11, bitscore:
                     35.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISLSLNSELQPATTSGEQAVSAVTKLRELLDEQAEATDQEGRF
                     ARESVDALVDAGLFAAAVPADLGGFGVERLHDLTVLTSRIARADASVAVAHYMHTALAW
                     YFARVVRFAADGEPGYLPRAQWLEAIGDRRMLLCSAVAERGADYWNLTTTATASYNGWV
                     INGRKILASVSPAATHFYCRLKAARGEGDHLASAMIPAATAGVHVEDDWQGLGLRGSGS
                     GTVLFNECVVPDDALLVRGPWGKRDAGMLEGRAVSGMGLNGVYLGLAEAARDHALWALT
                     ARASGRDRASAASVKYAVAEMETALIAARGTLATALQDFDAHLMLNKPQVITDDMSRAM
                     MKECQLVSLVVERAATEVVDHAMRLTGGASYQARHPLARAYRDVRAAAFMPPYSPPEDA
                     MDFVADTTLGLTGGRDGSE"
     misc_feature    complement(3882..3884)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5029..5838
                     /gene="pumF"
     CDS             5029..5838
                     /codon_start=1
                     /gene="pumF"
                     /product="pumF"
                     /protein_id="AVT42375.1"
                     /transl_table=11
                     /translation="MWNVTLQFSGWLTGDSTPSGTARRHELTEDEQVVIRYDPDTDSLG
                     FSSATRPQPAGVAVVTAHGDHWSLTNLHAEDTYFVENMEVGGEFVKVAPRRQDIPIPFE
                     LARLILPVPRGTGVVNVFGPEPRFLDASFAADRTTNWPRLDERCLYFRVLVALCEPQLR
                     GGPPGAVPTVMEVIARLGGRFSQRMSRAAVNHHIDYLATHKLRVSEWAGACDGKRSYWK
                     REAIVAMALRSGLVNEAHLELLPHRQVTGPQEPAPSSAPAPRSRSGR"
     misc_feature    5062..5064
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5774..7096)
                     /gene="pumG"
     CDS             complement(5774..7096)
                     /NRPS_PKS="Domain: Aminotran_3 (45-386). E-value: 1.6e-81.
                     Score: 265.8. Matches aSDomain:
                     nrpspksdomains_pumG_Aminotran_3.1"
                     /codon_start=1
                     /gene="pumG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 348.2;
                     E-value: 1e-105)"
                     /gene_kind="biosynthetic-additional"
                     /product="PLP-dependent aspartate aminotransferase"
                     /protein_id="AVT42376.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.3e-82, bitscore:
                     266.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGGMSLTNGENTDLDEERARERDRRFVWHPWSPVNKSGHDGPVL
                     VSGEGYRVRDATGRSYLDAMASAMNSSCGYAHPALLAAAERQLARLPHFDLSVGSHLPV
                     GRVAERLGGLMPEGLGRTLFVNSGSEATEAAVRIAHDYWTNKDEPRDRIVTFADGYHGT
                     TYVAQHLSGLPTNALYGDEPFPVTKVGSPLAPRELRTPEGLAALTEAFERAVLEGPPPA
                     AVFVEALLNVGGGVVLPGGLLRALRELCDRTGALLVLDEVFCGFGRTGRMFGFEHDGIT
                     PDLVTMSKGISGGYIPFAALTTTEEVYASFAADPLTGGLRYGHTTGGHAVACAVALAVL
                     DVMEEQKLVEASAALGGQLLDGLLPMLDHPEISDVRGLGLVATVECHRPEFAAGLVAGA
                     AARGVLLRRQGPCVMAIPPLIIDRSGIAELVHSTGQALADL"
     aSDomain        complement(5939..6961)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pumG_Aminotran_3.1"
                     /evalue="1.60E-81"
                     /label="pumG_Aminotran_3.1"
                     /locus_tag="pumG"
                     /protein_end="386"
                     /protein_start="45"
                     /score="265.8"
                     /tool="antismash"
                     /translation="VSGEGYRVRDATGRSYLDAMASAMNSSCGYAHPALLAAAERQLAR
                     LPHFDLSVGSHLPVGRVAERLGGLMPEGLGRTLFVNSGSEATEAAVRIAHDYWTNKDEP
                     RDRIVTFADGYHGTTYVAQHLSGLPTNALYGDEPFPVTKVGSPLAPRELRTPEGLAALT
                     EAFERAVLEGPPPAAVFVEALLNVGGGVVLPGGLLRALRELCDRTGALLVLDEVFCGFG
                     RTGRMFGFEHDGITPDLVTMSKGISGGYIPFAALTTTEEVYASFAADPLTGGLRYGHTT
                     GGHAVACAVALAVLDVMEEQKLVEASAALGGQLLDGLLPMLDHPEISDVRGLGLVATVE
                     C"
     gene            7158..7859
                     /gene="pumH"
     CDS             7158..7859
                     /codon_start=1
                     /gene="pumH"
                     /product="adenylate kinase"
                     /protein_id="AVT42377.1"
                     /transl_table=11
                     /translation="MIIEGAGGRQRPANGPRGKPTVTLHVLNPAAALPRRPDRVLIAGG
                     SGAGKTAVADKLATLLALPRIELDELYYQPGWEPRPEFAEDVARVSGAPRWITEWHYPE
                     VSGLLARRADLLVWLDYPTRTTMTSLVLRTLLRSLHKEVLWSGNQEPRLRAVLTDPEHI
                     LRYGWSTRHSARDEVRTLARRAPDITLDLLRFARPAELSDWLLRLAGTSYAPAPSGQPA
                     TERSTDASGLR"
     gene            7840..9447
                     /gene="pumI"
     CDS             7840..9447
                     /codon_start=1
                     /gene="pumI"
                     /product="glucose-methanol-choline oxidoreductase"
                     /protein_id="AVT42378.1"
                     /transl_table=11
                     /translation="MRQGFDDIVVGAGAAGVVLAACLSEDPARRVLLIEAGPDHPDPAH
                     LPADLRNGCTPSLVEHDWSLVGERRDGALLPLPRGRVVGGSSAVNSCIALRPEVDDFTR
                     WAKRAGGAAWSWPEILPFFTALESDADFGERHHGAHGPLPLRRPSRSALTPLSAALVET
                     ATAAGHPFVADHNAPGATGVGPLPLNLADRGRRVSAVAAYLDPVRKRPNLTVLADTLVD
                     RVLFEGTRARGVVTVADGGTTEVRGDRVTLCAGAYGTPALLHRSGIGPAALLRSLGVDV
                     VADLPGVGNGLSDHSQVPIGVIPPTAELCDPSVPCAQVVLRYTAPGSDVANDMQMYVLN
                     HVELDVYAPHLASRVPGGRAFMVTANLMAPRGRGTVTTVSRSPAIPPRIGIDYTADAED
                     LRRLRAGVGLCWEMLQQPAFTALTRDVIDMDAATVRSQARLDAFVRRAARTAHHPMGTA
                     RIGRADDPDAVVDERCRVYGTERLQVADASVIPVPVRANTHLVSLVIGERVAAWSRQAP
                     EAGPARAGATRSLRRRGK"
     misc_feature    9427..9429
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9444..10472
                     /gene="pumJ"
     CDS             9444..10472
                     /codon_start=1
                     /gene="pumJ"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: truD"
                     /gene_kind="biosynthetic"
                     /product="tRNA pseudouridine synthase TruD"
                     /protein_id="AVT42379.1"
                     /sec_met_domain="truD (E-value: 6.6e-63, bitscore: 201.6,
                     seeds: 30, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTLVLKHRQEDFRVRENLVVALTDAAAATHRYLLLHKRGHTTM
                     EAVRLVADRLGVAREDVGYAGLKDEDGITEQLLSVPLASLAADALPAAGLVEGAGPERM
                     LSLSHYGFGREPLTVGQLNGNGFRVVLRDLDEAAAARLVDRQRINLLFVNYYDTQRFGV
                     PGGPKRTHLVGEALLKEDWALARQELAGLGAPESGEAARWTGQDRALFRALDPRTVAFY
                     LAAYSSYDWNARVRDLIGSLCPDDAPESAVDGLPYRFPTTAEGVAALLAACHELPYTRY
                     AYRDGPVERPTTRPTVIQTAITVGADGPDDAFPGRRAVEVSFLLPSGCYATAALRQLVL
                     RR"
     gene            10581..11789
                     /gene="pumK"
     CDS             10581..11789
                     /codon_start=1
                     /gene="pumK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 72.7; E-value: 5.3e-22)"
                     /gene_kind="biosynthetic-additional"
                     /product="ATP-grasp domain protein"
                     /protein_id="AVT42380.1"
                     /sec_met_domain="ATP-grasp (E-value: 5.9e-08, bitscore:
                     22.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALLLLNRRPLLPLLPAWLPGASLIVLTARSVVGLPSSLPLPRER
                     FARFETVDDYESPEVDDLIDRICAEGGVERVVTTAEIDVVRAARARERHGLPGQSTASA
                     LAYRDKHRMKALAARHGVAVSPMAPVRDTGDLRSFAAAHGLPVVVKPADGAGSVGVRVL
                     RDARAVRGCALPADRAWLAERYVEGDICHVDGLMAKGAVLHGLASRYLHTNLDTATEGV
                     PSVSGMLAAADPLAGRLVAAAARVVAALPAVEEVTAFHAEFFHTPQDALVLCEIACRPG
                     GCGIAEAYALSTGVGLYEAHVRGQAGLSPDVPDPGRGYPRHGWGWFPPRRGTLVGLPAH
                     CPLPRARGYVTSGEPGRRYEGPRSSTDSVAELLFRVDDAEALTPQLREVDDWWSREVRW
                     AAP"
     gene            11774..13045
                     /gene="pumL"
     CDS             11774..13045
                     /codon_start=1
                     /gene="pumL"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 202.6; E-value: 1.2e-61)"
                     /gene_kind="transport"
                     /product="major facilitator superfamily protein"
                     /protein_id="AVT42381.1"
                     /transl_table=11
                     /translation="MGGTVTGTSGRAGAFMTAMVVDALGSGVWITFSLLYFTYGQGMAL
                     TAAGSALSAGSLTALLAGGLAAGVLTDRMGPFPAAVLSCAIRAVAFPCYLLADSPATVA
                     VTACAISFGDRLYWAAHAGLVGSVTTEEHEQRRLFALMNSLRNVGLGVGALAVALAASF
                     EEADGTALWHLIPLVNAVSFAVAGVMFRWVGRGSGPVASSQAGHRTGASYRGVLANRRF
                     LAFTGATLSLTLSSVAFDSILPVYLRSLGLPLWMPPVVYVLSCVAIPACQPLALSLGRR
                     YPPMRLMALAAALVAVSLGALVLLGSLAGVAGTVLIVLLVLVFSLGEAVFGAVAMTLVL
                     SFATPQDAGRYSALYQLAWGLSGALGPGVHTLLFSVSGSAPWAVMACALLVGAAVYLRL
                     ARTSPRDTAPAPHSGDPVDRKERT"
     gene            13042..14475
                     /gene="pumM"
     CDS             13042..14475
                     /codon_start=1
                     /gene="pumM"
                     /product="D-alanine-D-alanine ligase"
                     /protein_id="AVT42382.1"
                     /transl_table=11
                     /translation="MTSTSRRSHPPSPPDTGESAAATALIATVSGALWSFWAGRGVVLL
                     LDDFDHRATSLVGELRACGARVEAVISRTGPGPGAPEVAESWHCSDAGLRLSRPAFEAW
                     LRDPSDDVLRWLDARDPARQWLALGTPRTGAAEVLGRTVYGWRRPEWAAIEDKTTIDRL
                     WAAAGVASPPYLVGQVEDVLRRPDAAAGIGGPAGVVVAADSTRGHVGDSLGLRWVPRPG
                     GFVDAVRDLAGRSDRVRVARFADGVPCSVLGMALPDGIAVFAPIEIVTLGDPSTGRLLF
                     CGSSTHWRPGDEAERDIRGAARRAGAELVRTTGYRGIFSVDGLLTPEGFTATELNPRHA
                     SGLGLRAARPDFPVYLFNRAVQEELPGLEGVGSAALERFVRRAVAAAPSYALTVPVTAA
                     GHPDGPGRLHHGGQAIDHHTADGVAALSALTPPAAGHRAGPACAALAAHLGDPGLCSFP
                     LGAEAAQGPGTPGRTETAH"
     gene            14501..15643
                     /gene="pumN"
     CDS             14501..15643
                     /codon_start=1
                     /gene="pumN"
                     /product="amidinotransferase"
                     /protein_id="AVT42383.1"
                     /transl_table=11
                     /translation="MSRPVSLVNSWNEWDPLREIVVGIADNACFEPSEPGYRPQLRTRD
                     GRAAPFPTGPKPAEMIDRANEQLDGLVALLTSQGVTVRRPEAPGAPGPLRTPDFEVANP
                     YCVVCPRDVMITLGNEIIEATMSRRARYFEYQAYRKLVYEYWRGDPDMVWTVAPKPSMA
                     DSMYREGFWDWPLEKRHREMHSYEFCVTQDEVVFDAADISRFGRDIVVQESMTTNRLGI
                     HWLKRHLEPRGFRVHPVHFPLDFFPSHIDCTFVPLRPGLVLTNPERPLREGEEQLFLRN
                     GWELIDVPHPTSTNDEMPAHCQSSKWLSMNVLSISPTKVVCEAQEKPLQDLLDKLGFEV
                     FPVPFRDVFEYGGSLHCATWDVNREGTAEDYFAAGYRPLA"
     gene            complement(15726..16358)
                     /gene="pumO"
     CDS             complement(15726..16358)
                     /codon_start=1
                     /gene="pumO"
                     /product="pumO"
                     /protein_id="AVT42384.1"
                     /transl_table=11
                     /translation="MGAPLGSELSSERLAARQQELQAEADAVAADLDLVRLLSTRGEAV
                     RVGSAALGLMVLPDLDITVVCPELEADTRRAVAGIGAELAVHDRVRQVTFRDDTGEWNT
                     DPRYPDGLYLNIHYRSRAGRDWTLDIWFVDEPDRQPDLAHARTLPPRLTDAHRAAILRI
                     KQVLASRTGARVPSYEVYRAVLDGEVTTADAFDEWYAGEQAGRPGQE"
     gene            complement(16556..17038)
                     /gene="pumP"
     CDS             complement(16556..17038)
                     /codon_start=1
                     /gene="pumP"
                     /product="HAD family hydrolase"
                     /protein_id="AVT42385.1"
                     /transl_table=11
                     /translation="MDKVALTAAGLYVIVLLRAGGTFAVGWLAGAGVRRSRFAERISPA
                     KFERAERAIQRWGAPVVALSFLTVGFQTAANFLAGSMRMPLLRYLPALFVGGAGWALVY
                     ATAGIGALEMLARLFAEQTALGVAAVAALLLAVCGVGVYRRRHAALTTRDTAADES"
ORIGIN
        1 gcacttcacc atccggtcga ccgcttctcg gtccaaaggc gcggcagtcg aggaaagctg
       61 cggcaacaac cggtcgaagg cgtccaccat ctcgggggtc gcctcgcgaa cgatctctac
      121 gtcaacggtc atgcgctccg ccttccggaa tgcggcccga gtgtcgcgac ccgggaaccg
      181 cagggtgggg tggggtgatc tcgcggtgaa cagcctgtct cagcccggcc ggggcagtgg
      241 gggcgtgcac tcgtagggcg tacctcgcag cacggtgtcg acgaagcggc cgcgtggccc
      301 ggaattctcg gcgaaccacg acccgagccg gtggtcggtt ccggggtgga cgagccgggt
      361 gaagcgcgag cgcgacgtgt gcccggagaa gtcgcaggcg agagcgtggt gtccgcgggc
      421 ggcgaagtcg gtcagcagag cggtgtggcg tgtcttgtca ccggtgcccg caccgtgcag
      481 aacggcagcc gcaagggggg cgcgcgggct cgtgggtgtc cgcggcggct cgatggccgc
      541 gcaactgagg gtttcgccgt cgcagttgat ggtgaacgag cggagcctct cgtggtgcgg
      601 gctcatcggg ctgctgccgg tcataccgcc tccgtctcca ggcgagcagg ggcgtgacgt
      661 gacggccgga cgatggcggc cgtggcggcg gcgatgacgc agcacagcac ggggaggaag
      721 agggtgaggt tgaggggcag gacgtgggtc atcggtccga tgacggcggg cccggcgagc
      781 atgccgaggt agccgaggcc ggcgacgcgg gagacgttgg taccggcggc accctggtcg
      841 gtatggccgg ccgcgctgaa gagctggggt acgcatccgg agagtccggc cccgaacacg
      901 gcccagccga tcagagccaa ggggatccag ggtgagaggg ccgccgcggt cagaccgagg
      961 gcggcgacgg atgcgccgtg gcggaggatg gccaccggcc cgaagcgcgc ggccacccgg
     1021 tcggcaagca ggcggccgag ggtcatggtg gtggcgaagg agccgtaggc gagtgcggcg
     1081 gtggcggcgg gcgcgtccag gacgttgcgc agatgcagtg cgctccagtc gttggccacg
     1141 ccttcggaca gcatgatcat caatgccagg gtggccagtg cccagatgtg acggggcgtt
     1201 ctgcgagggg cgttcacgac agcgacggcg gcctccacgg ggcggcgggc ctcggcgggg
     1261 cgcaggagcg cgggcgccgc gaacgcggtg acggccagac cgacgagcgc caccgtgccg
     1321 agggtcgtta ccggactcca gtgccagccg agcgtgcggg cgccgaccag cgaggcaagg
     1381 accccgccga gggagaaggc cgcatggaag gcggacatga cgggccgccg gtacccctgc
     1441 tcgacctgga cggcatgggc gttcatgctg acatccaggc agccgttgcc gacgccgagc
     1501 acgaggagtg ccgcccccag cgtccaggcg ttcgcggcca ggccgggcag gacgagcgcg
     1561 gcactgcaca gtgccgcgct gagcggtacg acggtacggg acccgaaacg gtcggtgagc
     1621 gggccggtgg cctgcatgcc cgcgaaggct cccgcaccga gcagcagcag gagccagccg
     1681 agcagggcat ggctgatccc cgcgcggtgc tcgatgcccg ggatatggac gatccacatc
     1741 cccatgagga aaccgttcag ggtgaagtac gcgaaggtgg ccagtcggcc ggctcgtagg
     1801 tatctatcca cgcttcgaac ataacgaaca ttacccagga gcgaaagatt gctcttcgaa
     1861 cacgatggat gttcaatggg ggtatggtta gcacagatcg actgaggcag atcactgagg
     1921 ccgtacggga ggcgggccgc gtcggcgtcg cggaactggc agcgctcacc ggcgcatcgg
     1981 agatgaccat ccgccgcgac ctcgaagtcc tcgcggacca gggtgtgttg gagcgctacc
     2041 gcggaggggc caggagcctg ctgctgcggg gcgaggaacc gcccttcgca ctgcgggccc
     2101 aggaagggac ggccgtcaaa cggcgcatcg ccgccgaagt cgcggacctg atcgccgacg
     2161 gggagtccgt cgttctcgac agcggcacca cctgtctgga ggtggctcgt gcactggagc
     2221 accgccgcct gaccgtcgca ccgctctccc tgcacgcggt gaacgcgctg tccggagccc
     2281 cgaacgtgac cctgctggtg cccggtggcc ggccacgatc gggggaactg gccctcaccg
     2341 gcccgctgac ccaggcatcg ctggccgcgc tgcgttttga caccgcggtc atcagctgct
     2401 gcggactcac cgcggcgaac ggcctgaccg cctacgacct ggacgacgcg gcggtcaagc
     2461 gcacagcgat cgcctccgcc cgccgagtca tcgccgtcac ggagtccgcg aagctgtccc
     2521 gcaccgcact cgccttcgtc gcgcccgcct ccgcgctgca tgcgctggtg accgacgagg
     2581 ccgccccgga ggacgagacc ggcgcgatca cggccgccgg cgtcaccgta cggaaggtgt
     2641 gaccacgtga cgggcaccgt gctcttcgac ctcttcggcg tcatcgcacg ccatcagtcc
     2701 accgaaggca agaaccggct cacccggacg gcaggagtgg cggggccggc cttctgggac
     2761 gcctactggg agctgcgccc gccctacgac cgtggtgagg tgaacggccc cggctactgg
     2821 cgtcaggtgg ccgacgccat cggcgtccgc ttcgacgacc accggatcgc cgacctcgtc
     2881 gaggccgaca tcgcgagctg gagtgcggtc gacgacacga tggtcgccct gatagaggaa
     2941 ctcaccgcca caggccgcca catggggctg ctgtccaaca tccccgaaga gctggcctcg
     3001 cactatgaag cgcatcatgc ctggctcaag cacttcccgg tacgggcctt ctcatgtcgc
     3061 atgggccacg ccaagcccga gcgcgccgcc tacgagtggt gtcagcacgc cctgcgtacg
     3121 gagccggacc gcatcctctt tgtcgacgac cgcgcggaca acgtacgtgc cgccgaagaa
     3181 ctcggcatgc agggacacct cttcaccacc ccggaccggc tgaggcaggc tctcagtcaa
     3241 tggacctgac caggcacccg ccggccgagc cctggcctcc gagcacccgc actgacggcc
     3301 atgcgaaggt gcttcgccgc ggatgcggcc ggactggcgg ggatccgcat ccccgtgtca
     3361 tcgcgcagcg ggcgggcccg gcagcccgcc ggctgccgag gtgtatctgc ggcccggccc
     3421 gtcaggacgg gccgggccgc attgccgcag cgaagctcac actccgctgc cgcacccctt
     3481 ggtcggaacc ggtagcgaca tggatgtcgt cgggtcggcg gtcgcctagg ggtgtccgcg
     3541 gcggcatctg ccacggaaac tcaggggccg tcagctcact cggatccgtc ccggccgccc
     3601 gtcaggccca gcgtggtgtc ggcgacgaag tccatcgcgt cctccggcgg cgagtacggc
     3661 ggcatgaagg ccgccgcccg cacgtcgcgg taggcacggg cgagagggtg gcgcgcctgg
     3721 taactcgcgc cgcccgtcag gcgcatggcg tggtccacga cctcggtggc ggcgcgttcc
     3781 accaccaggc tgacgagctg gcactccttc atcatggccc ggctcatgtc gtcggtgatc
     3841 acctgtggct tgttcagcat cagatgggcg tcgaagtcct gtaaggcggt ggcgagcgtg
     3901 ccacgtgccg cgatcagcgc ggtctccatc tcggcaacgg cgtacttgac ggatgccgcg
     3961 ctcgcccggt cgcgccccga cgcgcgtgcg gtcagggccc acagcgcgtg gtcgcgggcc
     4021 gcctcggcga gcccgagata gacgccgttg agccccatgc cgctgaccgc gcgcccctcc
     4081 agcatgccgg cgtcacgctt gccccagggg cctcgcacca gcaacgcgtc gtcgggtacg
     4141 acgcactcgt tgaagagcac ggtgccgctt ccggagccgc gcagccccag cccctgccag
     4201 tcgtcctcca cgtgcacccc ggccgtggcg gcggggatca tggcgctcgc caggtggtcc
     4261 ccttcgccgc gtgccgcctt gagccggcag tagaagtgcg tcgcggcggg cgacacggag
     4321 gccaggatct tgcggccgtt gatcacccag ccgttgtacg aggcggtcgc tgtggtggtc
     4381 aggttccagt agtcggcccc gcgctcggcg acggcggagc acagcagcat ccgacggtcg
     4441 ccgatggctt ccagccactg cgcgcgaggc agatagccgg gctcaccgtc cgccgcgaaa
     4501 cgaacgacac gggcgaaata ccacgccagg gccgtgtgca tgtagtgggc gacagcgacc
     4561 gaggcgtcgg cgcgggcgat gcgcgaggtg agcaccgtca ggtcgtgcag ccgctcgacg
     4621 ccgaatccgc ccaggtcggc ggggaccgca gcggcgaaca gtccggcgtc caccagagcg
     4681 tcgacgcttt cgcgcgcgaa gcgcccctcc tgatcggtgg cctccgcctg ttcgtcgaga
     4741 agttcccgca gtttcgtgac cgccgagacc gcctgctcgc cgctcgtcgt ggccggttgc
     4801 aactcggagt tcaacgacag ggaaatcgac atgatgcctc cacgtttatc aggtacccgg
     4861 cagcttttgg ccattgcctg cgaagaaaac cacgcccggc gaccgaaagg attcggccga
     4921 tcagctacgg atcttgcccg tcaacgggcc cccggttagc gtggatctca ccagcggaac
     4981 ggcgaattca agttcctgac agcgacgttc ggaaaaggat cctttacagt gtggaacgtc
     5041 actcttcagt tttccggatg gttaaccggg gattcgacac cctcgggtac ggcccgacgc
     5101 cacgaactca ccgaggacga gcaggtggtg atccggtacg acccggatac cgattccctc
     5161 ggcttctcgt ccgccacgcg ccctcaacca gccggtgtcg ccgtggtcac cgcccatggc
     5221 gaccactgga gcctgaccaa tctgcacgcc gaggacacct acttcgtcga aaacatggag
     5281 gtcggcggag agttcgtcaa ggtggctccc cgccggcagg acatccccat tcccttcgaa
     5341 ctggcgcggc tgatactgcc ggtgccacgc gggaccggag tcgtcaatgt attcggcccc
     5401 gaaccccgtt ttcttgacgc ttccttcgcg gcggaccgca ccaccaactg gccgcggctc
     5461 gatgagcggt gcctctattt ccgtgttctt gtcgccctgt gcgaacccca gttgcggggt
     5521 ggtccgcccg gcgccgtacc gaccgtcatg gaggtcatcg cccggctcgg gggacgcttc
     5581 tcgcaacgga tgagccgggc cgccgtcaac caccacatcg actatctggc gacgcacaag
     5641 ttgcgggtga gcgaatgggc cggtgcctgc gacggaaagc gctcctattg gaagcgggaa
     5701 gcgatcgtgg cgatggccct gcgttccggt ctggtgaatg aggcgcatct ggagctgctc
     5761 ccccaccggc aggtcacagg tccgcaagag cctgccccgt cgagtgcacc agctccgcga
     5821 tcccggagcg gtcgatgatc agcggcggga tggccatcac acaggggccc tgccggcgca
     5881 gcagcacgcc gcgcgctgcc gccccggcca ccagtccggc cgcgaactcg ggacggtggc
     5941 actcgaccgt cgccacgagc ccgagcccgc gcacatcgct gatctccggg tggtcgagca
     6001 tcgggagcag cccgtcgagc agttgcccgc cgagcgccgc ggatgcctcg accagcttct
     6061 gttcctccat gacgtcgagc acggcgaggg cgaccgcgca ggccaccgcg tgtccaccgg
     6121 tcgtgtggcc gtagcgcaga cctccggtga gcggatcggc ggcgaaggac gcgtagacct
     6181 cctccgtggt ggtcagcgcc gcgaagggga tgtagccgcc gctgatgccc ttgctcatgg
     6241 tgaccaggtc cggcgtgatg ccgtcgtgtt cgaagccgaa catccggccg gtgcggccga
     6301 acccgcagaa cacctcgtcc aggacgagca gggcaccggt ccggtcgcac agctcgcgca
     6361 gggcgcgcag caggccgccg ggcagcacca caccaccacc gacgttgagc aacgcctcga
     6421 cgaagaccgc ggcgggcggc ggtccttcga gtacggcacg ctcgaacgcc tcggtcagcg
     6481 ccgccagccc ctccggtgtg cgcaactccc gcggcgcgag cggtgagccc accttggtca
     6541 ccgggaacgg ctcgtcgccg tagagggcgt tggtcggcag cccggacagg tgctgggcga
     6601 cgtacgtggt gccgtggtag ccgtcggcga aggtgacgat ccggtcgcgg ggctcgtcct
     6661 tgttggtcca gtaatcgtgg gcgatccgca ccgcggcctc ggtggcctcc gaaccgctgt
     6721 tgacgaacag ggtccgtccg agcccttccg gcatcaggcc gccgaggcgt tcggcgacgc
     6781 ggccgaccgg caggtgcgag ccgacgctca ggtcgaagtg cggcagccgg gccagctgtc
     6841 gctcggccgc cgcgagcagg gccggatggg cgtatccgca gctggagttc atcgctgacg
     6901 ccatcgcgtc gaggtaggag cgtcccgtcg cgtcccgcac gcggtatccc tcgccggaga
     6961 ccagcaccgg gccgtcgtgt ccggacttgt tcacagggga ccacgggtgc cacacgaagc
     7021 gcctgtcgcg ctcacgggcc cgctcctcgt ccaagtcggt gttctcaccg ttggtaagcg
     7081 acatgccgcc gatcatgcag gccggccggc ccgcgcacac ccccacacat gtcagggcgc
     7141 caagtcgcgg agttctggtg atcattgagg gcgccggcgg gcgacagcgg ccggcgaacg
     7201 gaccgagagg aaagccgacg gtgactctgc acgtgctcaa cccggcggcg gccctgccgc
     7261 gccgcccgga cagggtgctg atcgcgggcg gcagcggcgc gggcaagacg gctgtcgccg
     7321 acaaactcgc cacgctgctg gcgctgcccc gcatcgaact ggacgagctg tactaccagc
     7381 ccggctggga gccgcgcccc gagttcgccg aggacgtcgc gcgggtctcc ggggcgcccc
     7441 ggtggatcac cgagtggcac tacccggagg tctccggcct cctcgcgcgc cgcgccgatc
     7501 tgctcgtctg gctcgactac ccgacccgca cgacgatgac cagcctggtg ctgcggaccc
     7561 tgctgcggtc gctgcacaag gaggtgctgt ggagcggcaa ccaggaaccg cggttgcggg
     7621 cggtgctcac cgacccggag cacatcctgc gctacggctg gtcgacccgg cactcggccc
     7681 gtgacgaggt gcggacactg gcccgacggg ctcccgacat cacgctggac ctgctgcggt
     7741 tcgcccggcc cgccgagttg tcggactggc tgctgcggct ggccggaacc tcgtacgccc
     7801 cggcgccgtc cgggcaaccc gccacggaga ggagtaccga tgcgtcaggg cttcgatgac
     7861 atcgtggtcg gcgcgggagc cgcgggggtg gtgctcgccg cctgtctctc ggaggacccg
     7921 gcacgccggg tcctgctgat cgaggcgggg cccgaccacc ccgacccggc ccacctcccg
     7981 gccgacctgc gcaacgggtg cacgccttcg ctggtggagc acgactggtc gctggtcggt
     8041 gagcgccgag acggtgcctt gctgccgctg ccgcggggcc gggtcgtcgg cggctcgtcg
     8101 gcggtgaaca gctgcatcgc gctgcgcccc gaagtggacg acttcacccg ctgggcgaag
     8161 cgggcgggcg gtgccgcgtg gtcatggccg gagatcctgc cgttcttcac cgcgctggag
     8221 tccgacgcgg acttcgggga acgccaccac ggtgcccacg ggccactgcc gctgcggcgg
     8281 ccctcccggt ccgctctcac accgctgtcg gcggccctgg tggagaccgc gaccgcggcc
     8341 ggccacccct tcgtggccga ccacaacgcc cccggggcca ccggagtcgg gccgctgccc
     8401 ctgaacctcg ccgaccgcgg gcgccgggtg tcggccgtgg ccgcatacct ggacccggtg
     8461 cggaagcggc cgaatctgac ggtgctggcg gacaccctcg tggaccgggt gctgttcgag
     8521 gggacccgcg cccgcggtgt ggtgaccgtc gcggacggcg gcaccaccga ggtgcgcggc
     8581 gaccgcgtca cgctgtgcgc gggcgcctac gggacccccg ccctgctgca caggtccggc
     8641 atcggcccgg ccgcgctgct gcgctcgctg ggggtggacg tggtggccga cctgcccggc
     8701 gtcggcaacg gcctctcgga ccactcccag gtccccatcg gggtcatccc gccgaccgcg
     8761 gagctgtgcg acccgtccgt cccgtgcgcc caggtcgtgc tgcggtacac cgcaccgggt
     8821 tcggacgtcg ccaacgacat gcagatgtat gtgctcaacc acgtggaact ggacgtctac
     8881 gccccgcact tggcgagccg ggtccccggc ggccgggcgt tcatggtcac cgccaacctg
     8941 atggcgcccc ggggccgggg cacggtcacc accgtctccc gctcccccgc cataccgccc
     9001 cgcatcggca tcgactacac ggcggacgcg gaggacctgc gccggctgcg ggccggggtc
     9061 ggactgtgct gggagatgct gcagcagccc gcgttcaccg cgctgacccg cgacgtcatc
     9121 gacatggacg cggcaacggt gcgttcgcag gcccggctgg acgcgttcgt ccgccgggcg
     9181 gcacggacgg cacaccaccc catgggcacc gcgcggatcg gccgggcgga cgatccggac
     9241 gcggtggtgg acgaacgctg ccgcgtgtac ggaaccgagc ggctgcaggt ggccgacgcc
     9301 tccgtcatcc cggttccggt acgcgccaac acccatctcg tctcgctcgt gatcggcgaa
     9361 cgtgtcgccg cctggtcacg gcaggcgccc gaagccggcc ctgcgagggc cggcgccacg
     9421 cggagcttac ggaggagagg caagtgaccg gcaccctggt gctcaagcac cgccaggagg
     9481 acttccgggt acgggagaac ctcgtcgtcg cgctgaccga cgccgcagcg gccacccacc
     9541 gctacctcct gctgcacaaa cgcggccaca cgacgatgga ggccgtgcgg ctcgtggcgg
     9601 accggctcgg tgtggcccgc gaggacgtcg gctacgcggg cctcaaggac gaggacggca
     9661 tcacggagca gctgctgtcc gtgccgcttg cttcccttgc cgccgacgcg ctgcccgccg
     9721 ccggtctcgt cgaaggggcg gggccggagc ggatgctgag cctgagccac tacggtttcg
     9781 gtcgtgagcc gctgaccgtc gggcagctca acggcaacgg cttccgggtg gtgctgcggg
     9841 acctcgacga ggcggccgcc gcccggctcg tggaccggca gcggatcaac ctgctgttcg
     9901 tcaactacta cgacacccag cgcttcggcg tacccggcgg ccccaaacgc acccacctgg
     9961 tcggcgaggc gctgctgaag gaggactggg ccctcgcacg gcaggagttg gcggggctcg
    10021 gcgctccgga gagcggcgag gccgcccggt ggaccgggca ggaccgggcc ctcttccggg
    10081 cgctcgaccc ccggaccgtg gccttctacc tggccgcgta ctcctcctac gactggaacg
    10141 cgcgggtccg ggacctgatc ggctctctct gcccggacga cgcccccgag agcgccgtgg
    10201 acggactgcc ctaccgcttt cccaccacgg cggaaggcgt ggccgcgctc ctcgcggcct
    10261 gtcacgaact gccgtacacc cgctacgcgt accgggacgg ccccgtcgag cggccgacga
    10321 cccggcccac ggtcatccag acggcgatca ccgtcggagc ggacggaccg gacgacgcct
    10381 tccccgggcg ccgggcggtg gaggtctcct tcctgttgcc ctcggggtgt tacgccacgg
    10441 cggcgctgcg gcagttggtc ctccgccgct gaggcgccgc caggtgtccg ctcgcgatgc
    10501 gtcccgtgcc gtcccgcccg cgcgctgggg gcggccggcc gcctcgtcgc tccgaggagt
    10561 gcgtccccga aaggctgtcc atggcgttgc tgctgctcaa ccgcaggccc ctgcttcccc
    10621 tgctcccggc gtggctgccg ggcgcgtccc tgatcgtcct gacggccagg tcggtcgtgg
    10681 ggctgccgtc gtccctgccc ctgccgcggg agcggttcgc ccgcttcgag accgtggacg
    10741 actacgagtc gcccgaggtc gacgacctga tcgaccggat ctgcgcggag ggcggcgtcg
    10801 agcgggtggt caccaccgcg gagatcgacg tggtccgcgc agcgcgggcg agggaacgcc
    10861 acggcctgcc cggccagtcg acggcgagcg cgctggccta ccgggacaaa caccggatga
    10921 aggcgctggc ggcccggcac ggcgtcgcgg tgtcccccat ggcgcccgtg cgtgacaccg
    10981 gcgacctgcg gtccttcgca gcggcccacg gcctgcccgt ggtggtgaaa ccggccgacg
    11041 gcgcgggatc ggtcggggtg cgggtcctgc gcgacgcgcg ggcggtgcgc gggtgcgccc
    11101 tccccgccga ccgtgcctgg ctggccgaac ggtacgtcga aggcgacatc tgccatgtcg
    11161 acgggctgat ggcgaagggc gcggtcctgc acggtctcgc gtcccgctac ctgcacacca
    11221 acctcgacac ggcgacggag ggcgtgccca gcgtcagcgg catgctcgca gcggcggatc
    11281 cactggccgg ccggctggtg gccgcggcgg cacgggtggt cgcggcgctg cccgccgtcg
    11341 aggaggtgac ggccttccac gccgagttct tccacacccc gcaggacgcg ctggtcctgt
    11401 gcgagatcgc ctgccgcccc ggtggctgcg gcatcgccga ggcgtacgcg ctctcgacgg
    11461 gggtcggcct ctacgaggcg catgtgcggg gccaggccgg gctgtccccc gacgtgccgg
    11521 acccggggcg tggatatccg cgccacggct ggggctggtt cccgccccgg cgcggaaccc
    11581 tggtggggct gcccgcccac tgcccgctgc cccgcgcacg cggctacgtc acctcgggcg
    11641 agcccggaag gcggtacgag gggccgcggt ccagtacgga cagcgtcgcc gaactcctct
    11701 tccgggtcga cgacgccgag gcgctcaccc cgcagttgcg ggaggtcgac gactggtggt
    11761 cgcgggaggt ccgatgggcg gcaccgtgac cgggacctcg gggcgcgccg gcgccttcat
    11821 gacggcgatg gtcgtggacg cgctgggcag cggcgtctgg atcacgttct ccctgctgta
    11881 cttcacctac ggccagggca tggcgctgac cgccgccggc agcgcgctca gcgccggctc
    11941 gctgaccgcg ctgctggccg gtgggctggc cgccggggtg ctcaccgacc ggatggggcc
    12001 gttccccgcc gcggtgctca gctgcgcgat ccgggcggtg gccttcccct gctacctgct
    12061 cgccgacagt cccgcgacgg tcgccgtcac cgcctgcgcc atcagtttcg gcgaccgcct
    12121 gtactgggcg gcccatgcgg gtctggtcgg cagcgtcacc accgaagagc acgagcagcg
    12181 ccgcctgttc gccctgatga acagtctgcg caacgtcggg ctcggggtgg gcgcgctggc
    12241 ggtggcgctg gcggcctcgt tcgaggaggc cgacggcacc gcgctgtggc acctcatccc
    12301 cctggtcaac gccgtgagct tcgccgtcgc cggcgtcatg ttccgttggg tgggccgcgg
    12361 ttcgggtccg gtggcctcgt cacaggcggg ccaccggacc ggcgcctcgt accgcggggt
    12421 cctcgccaac cgccggttcc tcgccttcac cggcgcgacg ctctccctca ccctctccag
    12481 cgtggcgttc gactcgatcc tgcccgtcta tctccggtcg ctgggcctgc cgttgtggat
    12541 gccaccagtg gtctacgtgc tgtcctgcgt ggcgatcccg gcgtgccagc cgctggcgct
    12601 gtcgctgggc cgccggtacc cgccgatgcg gctgatggcg ctggccgccg cgctggtcgc
    12661 ggtctccctc ggggcgctgg tcctgctcgg cagcttggcg ggcgtcgccg gcacggtact
    12721 gatcgtcctg ctcgtcctgg tgttcagcct gggggaggcg gtcttcgggg cggtcgccat
    12781 gaccctcgtg ctgtcgttcg ccacaccgca ggacgccggc cgctacagcg ccctctacca
    12841 gctcgcctgg ggcctgtcgg gcgcgctggg ccccggcgtg cacacgctgc tgttctccgt
    12901 gtcgggcagc gcgccgtggg ccgtgatggc gtgcgcgctg ctcgtgggcg ccgccgtcta
    12961 tctcaggctc gccaggacct caccccgcga cacagcaccg gcaccgcaca gcggtgaccc
    13021 ggtcgaccgg aaggaacgga catgaccagc acctccaggc ggtcccatcc cccgagcccc
    13081 ccggacaccg gggaatccgc agccgccacc gccctcatcg ccaccgtgtc cggggcgctg
    13141 tggagcttct gggccgggcg cggcgtcgtc ctgctgctcg acgacttcga ccaccgcgcc
    13201 acctccctcg tcggtgaact gcgcgcgtgc ggcgcccggg tggaagccgt catctcgcgc
    13261 accggcccgg ggcccggcgc gcccgaggtc gcggagagct ggcactgctc cgacgccggc
    13321 ctgcggctgt cccggcccgc tttcgaggcg tggctgcgcg atccgtccga cgacgtcctg
    13381 cgctggctgg acgcgcggga cccggcgcgg cagtggctcg cgttggggac cccgcggacc
    13441 ggggcggccg aggtcctggg acggacggtg tacggctggc ggcgccccga gtgggccgcc
    13501 atcgaggaca agaccaccat cgaccggctg tgggccgccg ccggggtggc ctcgccgccg
    13561 tacctcgtcg gccaggtcga ggacgtgctg cgccgccctg acgcggccgc cgggatcggc
    13621 ggaccggccg gggtcgtggt cgccgccgat tcgacccgcg gccacgtcgg ggactcgttg
    13681 ggcctgcgct gggtgccgcg ccccggcggt ttcgtcgacg ccgtacgcga cctcgccgga
    13741 cggagcgacc gggtacgggt ggcccggttc gctgacgggg tgccgtgcag cgtgctcggc
    13801 atggcgctgc ccgacgggat cgccgtgttc gcgccgatag agatcgtcac actgggcgat
    13861 ccgtcgaccg gcaggctgct gttctgcgga tcgtccaccc actggcggcc gggcgacgag
    13921 gcggagcggg acatccgcgg cgccgcccga cgcgcgggcg cggaactcgt ccgcaccacc
    13981 ggctaccgcg ggatcttcag cgtggacggg ctgctcaccc cggagggctt caccgcgacc
    14041 gaactcaatc cgcgccacgc ctccggcctc ggcctgcggg ccgcgcgtcc ggacttcccc
    14101 gtctacctgt tcaaccgcgc ggtccaggag gaactgcccg gactggaggg ggtcggcagt
    14161 gccgcgctcg aacggttcgt ccgtcgcgcc gtggcggcgg cgccgtcgta cgcgctgacg
    14221 gttccggtga cagccgccgg tcatccggac gggcccggac ggctgcacca cggcggacag
    14281 gccatcgacc accacacggc ggacggcgtc gcggcgctgt cggccctgac gcctccggcg
    14341 gcgggccacc gcgccggacc tgcctgcgcc gccctcgccg cccacctggg tgacccggga
    14401 ctgtgctcct tcccgctggg cgccgaagcc gcacagggcc ccgggacgcc cggccgcacg
    14461 gaaacagcgc actgaagaac gacagagagg gagtgtcacc atgagccgac cggtgagcct
    14521 ggtcaattcc tggaacgaat gggatccgct gcgggagatc gtcgtcggca tcgccgacaa
    14581 cgcctgcttc gagccgagcg aacccggata ccggccccaa ctgcggaccc gagacggccg
    14641 cgccgccccc ttccccaccg gccccaaacc cgccgagatg atcgaccgcg ccaatgagca
    14701 gctggacggt ctggtggcgc tgctcacctc gcagggggtg accgtccgca ggcccgaggc
    14761 accgggggcg ccgggcccgc tgcgcacccc ggacttcgag gtggcgaacc cgtactgcgt
    14821 ggtgtgcccc cgtgacgtga tgatcacgct gggcaacgag atcatcgagg ccacgatgtc
    14881 gcgccgggcc aggtacttcg agtatcaggc gtaccgcaag ctggtatacg agtactggcg
    14941 cggcgacccc gacatggtgt ggacggtggc gcccaagccg tcgatggccg actccatgta
    15001 ccgcgaggga ttctgggact ggcccctgga gaagcggcac cgggagatgc actcgtacga
    15061 gttctgcgtc acccaggacg aggtggtctt cgacgccgcc gacatcagcc ggttcggacg
    15121 ggacatcgtc gtgcaggagt cgatgaccac caaccgcctc ggtatccact ggctcaagcg
    15181 ccatctggag ccgcgcggct tccgggtcca cccggtgcac ttcccgctcg acttcttccc
    15241 ctcccacatc gactgcacct tcgtcccgct gcgccccgga ctcgtcctga cgaacccgga
    15301 acggccgctg cgtgagggcg aggagcaact gttcctgcgc aacggctggg aactcatcga
    15361 tgtcccccat ccgacgtcca ccaacgacga gatgccggcc cactgccagt cctccaagtg
    15421 gctgtccatg aacgtactga gcatctcgcc gacgaaggtg gtctgcgagg cccaggagaa
    15481 accgctccag gacctgctcg acaagctcgg cttcgaggtc ttccccgtgc cgttccgtga
    15541 cgtcttcgag tacggcggct ccctgcactg cgccacctgg gacgtcaacc gggagggcac
    15601 ggccgaggac tactttgccg ctggttaccg gccgttggcc taaggaccgt cgccgaggtc
    15661 ccgtgccgag ggggcggcgc cacgccaccg ccccttcggc agcgccgcgc cctgcccgcc
    15721 gtggctcact cctggccggg ccgcccggcc tgttccccgg cgtaccactc gtcgaaggcg
    15781 tcggcggtgg tgacctcgcc gtccagcacc gcgcggtaga cctcgtaact gggcacccgg
    15841 gcgccggtcc gcgaggccag tacctgcttg atccgcagga tcgccgcgcg gtgcgcgtcc
    15901 gtcagccggg gcggcagcgt ccgggcgtgg gccaggtcgg gctgccggtc gggctcgtcg
    15961 acgaaccaga tgtccagggt ccagtcccgc ccggcccgcg agcggtagtg gatgttgagg
    16021 tagagcccgt ccggatagcg gggatcggtg ttccactccc ccgtgtcgtc ccggaacgtc
    16081 acctgccgca cacggtcgtg caccgccagc tcggcgccga tcccggccac cgcccgccgg
    16141 gtgtccgctt ccaactcggg acagaccacg gtgatgtcga gatccggcag caccatcagg
    16201 cccagcgccg cgctccccac ccgcacggcc tcgccccgcg tcgacagcag ccgcacgaga
    16261 tcgaggtcgg ctgcgaccgc atcggcctcg gcctgtagct cctgctgccg tgctgccagc
    16321 cgttcactac tcagctcact tcccagcggc gcgcccacac acgtcctctc tcgatgccca
    16381 acgtccgtac gacaaaaggg cggtaacgga agcaaccgag cctaccggcg cccccaccgg
    16441 ggccgcccct tcccggccac cccgccgcat ggcgggcctc gggaggccgt accgagctcg
    16501 ggaatccgtc acgccgccgc ccgtacgcgc gacggcgccg gcacggcagg gcccttcagg
    16561 actcgtcggc cgcggtgtcg cgcgtggtca acgcagcgtg tctgcgccgg tacaccccca
    16621 cgccgcacac cgcgaggagg agggcggcga ccgcggccac accgagcgcc gtctgctcgg
    16681 cgaacagcct tgccagcatt tccagtgcgc cgatcccggc ggtcgcgtag accagcgccc
    16741 agcccgctcc ccccacgaac agtgcgggga ggtaacgcag cagaggcatg cgcatactcc
    16801 ccgcgaggaa gttggcggcg gtctggaaac cgacggtcag gaaggagagg gccaccaccg
    16861 gcgcgcccca ccgctggatc gcccgttcgg cgcgctcgaa cttggccggg gagatccgct
    16921 cagcgaacct gctgcgcctg acaccggcac cggcgagcca cccgacggcg aatgtccctc
    16981 cggctcgcag caggacgatg acgtagagac ccgcggccgt gagcgcgacc ttatccacga
    17041 cgcatcgccc tcggcgccag gccctggccg tggccggttt cccccgccac ccgcattcgc
    17101 ggttctcccc gaagcgggca cgcgacgggc acgagcctgt tgtccatacc tcacccgcat
    17161 ctgcttccgc cggttccgtc cctgcgttcg tgccggggcg gcgccggttc ccgggcccga
    17221 cgcagagcat tgctgcatcc ggggcttcca ggcacggccc ctcgccaggg gcacccgaca
    17281 cagccagggt aagcgaacgc gcgtgcccca ggtggacggc gctgggcgcc ggggagggaa
    17341 gacgtgactt ctcggccgtc gaagctgcgg acggcctcgc tgggcgggcc ccgccgggtg
    17401 gcgtggcccg cccggccgca ccccgcgcga cctcgccggt ggcccgtcgc cgacaccgct
    17461 cccggcatcg gcgacggcct ggtggccggt ggaaggttgc tcagtcgtgg gcgtcgagcc
    17521 tgaagtggaa gattccccag gtgaggtgct tctcgcggcc accgtcgatc cagtggccga
    17581 gtcccttctt catctgggcg aggtagtcgt gactgatctt tctggccagc ccttcggcct
    17641 cttggtgcct ggtctcctca aggacccgcg tgtagtggtt caccagctgt tcgcggtgct
//
