Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001477.1:
Cluster 1NRP / Polyketide1116700

BGC0001477, lydicamycin biosynthetic gene cluster from Streptomyces sp. ID38640. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: lydicamycin
ChemSpider ID: 4943765
SMILES string: Copy to clipboard
Molecular formula:
Average molecular mass: Da
Molecular activity: Antibacterial

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Other (linear)
Thioesterase type:
Unknown
Release / cyclization type:
None

Nonribosomal peptide synthetases:
No gene ID (AVV61977.1)
Module 0
A specificity: Unknown
Evidence for specificity: Unknown
C domain subtype: N/A
No gene ID (AVV61987.1)
Module 17
A specificity: Glycine
Evidence for specificity: Sequence-based prediction
C domain subtype: LCL
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Modular type I
Starter unit:
Unknown
Thioesterase type:
Unknown
Release / cyclization type:
None

Modular polyketide synthases:
No gene ID (AVV61979.1)
Module 1
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 2
AT specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61980.1)
Module 3
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 4
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 5
AT specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 6
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61981.1)
Module 7
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 8
AT specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61982.1)
Module 9
AT specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61983.1)
Module 10
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 11
AT specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 12
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61984.1)
Module 13
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 14
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61985.1)
Module 15
AT specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None
Module 16
AT specificity: Hydroxymalonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

No gene ID (AVV61989.1)
Module 18
AT specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
KR stereochemistry: Unknown
Scaffold-modifying domain: None

Gene cluster description

lydicamycin (BGC0001477). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank Not derived from GenBank. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Margherita Sosio (Naicons Srl)

Literature references