BGC0001479: anabaenopeptin NZ857 biosynthetic gene cluster from Nostoc punctiforme PCC 73102
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Location: 3,055,744 - 3,062,289 nt. (total: 6,546 nt).
This entry is originally from NCBI GenBank CP001037.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001479
Short description anabaenopeptin NZ857 biosynthetic gene cluster from Nostoc punctiforme PCC 73102
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: CP001037.1
Compounds
  • anabaenopeptin NZ857
  • nostamide A
Species Nostoc punctiforme PCC 73102 [taxonomy]
References
Chemical products information
anabaenopeptin NZ857
Copy SMILES
C45H59N7O10
Chemical database entries
NPAtlas
PubCHEM
nostamide A
Copy SMILES
C45H59N7O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Npun_F2460
  • ACC81021.1
3055744 - 3062289 (+) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ACC81018.1
  • hphB
(external) isocitrate/isopropylmalate dehydrogenase
  • Precursor biosynthesis
Other in vivo study
  • ACC81019.1
  • hphC
(external) homoaconitate hydratase family protein
  • Precursor biosynthesis
Other in vivo study
  • ACC81020.1
  • hphD
(external) conserved hypothetical protein
  • Precursor biosynthesis
Other in vivo study
  • ACC81022.1
  • aptB
(external) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
  • ACC81023.1
  • aptC
(external) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
  • ACC81024.1
  • aptD
(external) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
  • ACC81025.1
  • hphA/aptE
(external) pyruvate carboxyltransferase
  • Precursor biosynthesis
Other in vivo study
  • ACC81026.1
  • aptF
(external) ABC Transporter
  • Transport
Other in vivo study
NRP-specific information
Subclass n/a
Cyclic? yes
Release type
  • Hydrolysis
Thioesterase genes
  • npun_rs12365 (Type I)
  • wp_012409018.1 (Type I)
NRP-synthases
Gene Modules
ACC81021.1
Module 0
Specificity: Phenylalanine
Evidence for specificity:
  • Structure-based inference
Module 1
Specificity: D-lysine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Dual
ACC81022.1
Module 2
Specificity: Isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: DCL
ACC81023.1
Module 4
Specificity: N-methylglycine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module A3
Specificity: Homophenylalanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Modification domains: Methylation
Module B3
Specificity: Homotyrosine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Modification domains: Methylation
ACC81024.1
Module 5
Specificity: Homotyrosine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: B54ZPFB4PBVBWY2K6JZNBOD5, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
Similar known gene clusters
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Detailed domain annotation
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