BGC0001479: anabaenopeptin NZ857 biosynthetic gene cluster from Nostoc punctiforme PCC 73102
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Location: 3,052,001 - 3,081,156 nt. (total: 29,156 nt).
This entry is originally from NCBI GenBank CP001037.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001479
Short description anabaenopeptin NZ857 biosynthetic gene cluster from Nostoc punctiforme PCC 73102
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: CP001037.1
Compounds
  • anabaenopeptin NZ857
  • nostamide A
Species Nostoc punctiforme PCC 73102 [taxonomy]
References
Chemical products information
anabaenopeptin NZ857
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C45H59N7O10
Chemical database entries
NPAtlas
PubCHEM
nostamide A
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C45H59N7O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Npun_F2457
  • ACC81018.1
 3052002 - 3053093 (+) isocitrate/isopropylmalate dehydrogenase
  • Precursor biosynthesis
Other in vivo study
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  • Npun_F2458
  • ACC81019.1
 3053077 - 3054786 (+) homoaconitate hydratase family protein
  • Precursor biosynthesis
Other in vivo study
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  • Npun_F2459
  • ACC81020.1
 3054973 - 3055365 (+) conserved hypothetical protein
  • Precursor biosynthesis
Other in vivo study
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  • Npun_F2460
  • ACC81021.1
 3055744 - 3062289 (+) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
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  • Npun_F2461
  • ACC81022.1
 3062393 - 3065623 (+) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
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  • Npun_F2462
  • ACC81023.1
 3065708 - 3073444 (+) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
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  • Npun_F2463
  • ACC81024.1
 3073441 - 3077661 (+) non-ribosomal peptide synthetase
  • Scaffold biosynthesis
Sequence-based prediction
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  • Npun_F2464
  • ACC81025.1
 3077745 - 3078923 (+) pyruvate carboxyltransferase
  • Precursor biosynthesis
Other in vivo study
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  • Npun_F2465
  • ACC81026.1
 3079129 - 3081156 (+) ABC Transporter
  • Transport
Other in vivo study
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NRP-specific information
Subclass N/A
Cyclic? yes
Release type
  • Hydrolysis
Thioesterase genes
  • Npun_F2463 (Type I)
NRP-synthases
Gene Modules
Npun_F2460
Module 0
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Module 1
Specificity: lysine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Dual
Npun_F2461
Module 2
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: DCL
Npun_F2462
Module 3
Specificity: homotyrosine / homophenylalanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Module 4
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Modification domains: N-methylation
Npun_F2463
Module 5
Specificity: homotyrosine / homophenylalanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: B54ZPFB4PBVBWY2K6JZNBOD5, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Removed extra genes with no information
  • Fix coordinates
  • Corrected NRP module 3
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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