BGC0001480: tundrenone biosynthetic gene cluster from Methylobacter tundripaludum 21/22
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 833,380 - 853,163 nt. (total: 19,784 nt).
This entry is originally from NCBI GenBank NZ_JMLA01000001.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001480
Short description tundrenone biosynthetic gene cluster from Methylobacter tundripaludum 21/22
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
NZ_JMLA01000001.1
833380 - 853163
via Knock-out studies, Gene expression correlated with compound production
Compounds
  • tundrenone
Species Methylobacter tundripaludum 21/22 [taxonomy]
References
Chemical products information
tundrenone Evidence: NMR, Mass spectrometry
Copy SMILES
C22H28O8
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • T451_RS0104065
  • WP_160171839.1
833404 - 834075 (+) HAD-IB family hydrolase
    copy AA seq
    copy Nt seq
    • T451_RS0104070
    • WP_027148169.1
    834124 - 835275 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • T451_RS0104075
      • WP_027148170.1
      835318 - 836016 (+) AfsA-related hotdog domain-containing protein
        copy AA seq
        copy Nt seq
        • T451_RS0104080
        • WP_027148171.1
        836018 - 837613 (+) FAD-dependent monooxygenase
          copy AA seq
          copy Nt seq
          • T451_RS0104085
          • WP_027148172.1
          837627 - 838616 (+) aldo/keto reductase
            copy AA seq
            copy Nt seq
            • T451_RS0104090
            • WP_027148173.1
            838629 - 840170 (+) MDR family MFS transporter
              copy AA seq
              copy Nt seq
              • T451_RS23295
              • WP_051604059.1
              840249 - 841424 (+) HlyD family secretion protein
                copy AA seq
                copy Nt seq
                • T451_RS0104100
                • WP_006890610.1
                841445 - 841687 (+) acyl carrier protein
                  copy AA seq
                  copy Nt seq
                  • T451_RS0104105
                  • WP_027148175.1
                  841696 - 843009 (+) hypothetical protein
                    copy AA seq
                    copy Nt seq
                    • T451_RS23300
                    • WP_027148176.1
                    843021 - 844622 (+) Acyl-CoA ligase
                    • Scaffold biosynthesis
                    • Knock-out
                    copy AA seq
                    copy Nt seq
                    • T451_RS0104115
                    • WP_027148177.1
                    844771 - 845589 (+) alpha/beta hydrolase
                      copy AA seq
                      copy Nt seq
                      • T451_RS0104120
                      • WP_235202197.1
                      845695 - 847065 (+) TolC family outer membrane protein
                        copy AA seq
                        copy Nt seq
                        • T451_RS0104125
                        • WP_027148179.1
                        847252 - 848274 (+) NAD(P)-dependent alcohol dehydrogenase
                          copy AA seq
                          copy Nt seq
                          • T451_RS0104130
                          • WP_081813268.1
                          848543 - 850246 (+) chorismate-binding protein
                            copy AA seq
                            copy Nt seq
                            • T451_RS0104135
                            • WP_027148181.1
                            850249 - 850893 (+) aminodeoxychorismate/anthranilate synthase component II
                              copy AA seq
                              copy Nt seq
                              • T451_RS0104140
                              • WP_027148182.1
                              850984 - 851631 (+) glutathione S-transferase
                                copy AA seq
                                copy Nt seq
                                • T451_RS0104145
                                • WP_036304852.1
                                851857 - 852282 (-) DUF4902 domain-containing protein
                                  copy AA seq
                                  copy Nt seq
                                  • T451_RS0104150
                                  • WP_006890625.1
                                  852453 - 853163 (+) LuxR family transcriptional regulator
                                  • Regulation
                                  • Other in vivo study Activity assay
                                  copy AA seq
                                  copy Nt seq
                                  Biosynthesis information
                                  Annotation changelog

                                  Entry version: 2

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  Migrated from v1.4
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 1

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  Submitted
                                  • (ID: T4ZY6CWFJ6LI7OH7I2U6R7OF)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  Similar known gene clusters from MIBiG 4.0
                                  Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                  Click on reference genes to show details of similarities to genes within the current region.
                                  Click on an accession to open that entry in the MiBIG database.