BGC0001484: 2'-chloropentostatin biosynthetic gene cluster from Actinomadura sp. ATCC 39365
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Location: 1 - 36,432 nt. (total: 36,432 nt).
This entry is originally from NCBI GenBank KP025768.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001484
Short description 2'-chloropentostatin biosynthetic gene cluster from Actinomadura sp. ATCC 39365
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
KP025768.1
via
Compounds
  • 2'-chloropentostatin
  • 2'-amino-2'-deoxyadenosine
Species Actinomadura sp. ATCC 39365 [taxonomy]
References
Chemical products information
2'-chloropentostatin Evidence:
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C21H27Cl1N10O7
2'-amino-2'-deoxyadenosine Evidence:
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C10H14N6O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • APC23279.1
 1 - 418 (-) hypothetical protein
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    • AKQ99277.1
    		 675 - 2054 (-) pentachlorophenol 4-monooxygenase
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      • AKQ99278.1
      		 2109 - 5162 (-) XRE family transcriptional regulator
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        • AKQ99279.1
        		 5278 - 6060 (-) s-adenosyl methyltransferase
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          • AKQ99280.1
          		 6127 - 6726 (-) bacterial regulatory proteins,tetR family
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            • AKQ99281.1
            		 6843 - 7601 (+) methyltransferase type 11
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              • AKQ99282.1
              		 7673 - 10858 (+) hypothetical protein
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                • AKQ99283.1
                		 10898 - 12337 (-) cation/H(+) antiporter
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                  • AKQ99284.1
                  		 12392 - 13600 (-) major facilitator superfamily
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                    • AKQ99285.1
                    		 13672 - 14559 (-) ATP phosphoribosyltransferase
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                      • AKQ99286.1
                      		 14604 - 15308 (-) short-chain dehydrogenase
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                        • AKQ99287.1
                        		 15295 - 16014 (-) SAICAR synthetase
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                          • AKQ99288.1
                          		 16239 - 17516 (+) aminotransferase
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                            • AKQ99289.1
                            		 17509 - 18564 (+) dehydrogenase
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                              • AKQ99290.1
                              		 18593 - 20380 (+) ABC transporter,partial
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                                • AKQ99291.1
                                		 20402 - 22180 (+) ABC transporter
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                                  • AKQ99292.1
                                  		 22177 - 22662 (+) NUDIX hydrolase
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                                    • APC23280.1
                                    		 22659 - 23396 (-) phosphoribosyl isomerase A
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                                      • AKQ99293.1
                                      		 23580 - 24446 (+) ATP phosphoribosyltransferase
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                                        • AKQ99294.1
                                        		 24455 - 25249 (+) hydrolase
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                                          • AKQ99295.1
                                          		 25374 - 26417 (+) ABC transporter substrate-binding protein
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                                            • AKQ99296.1
                                            		 26414 - 27505 (+) sugar ABC transporter permease
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                                              • AKQ99297.1
                                              		 27502 - 28722 (+) ABC transporter permease
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                                                • AKQ99298.1
                                                		 28722 - 30824 (+) hypothetical protein
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                                                  • AKQ99299.1
                                                  		 30826 - 31737 (+) hypothetical protein
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                                                    • AKQ99300.1
                                                    		 31734 - 32663 (+) pfkB family carbohydrate kinase
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                                                      • AKQ99301.1
                                                      		 32660 - 33385 (+) bacterial regulatory protein,gntR family
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                                                        • AKQ99302.1
                                                        		 33444 - 34139 (+) bacterial regulatory protein,luxR family
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                                                          • AKQ99303.1
                                                          		 34188 - 35120 (+) hypothetical protein
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                                                            • AKQ99304.1
                                                            		 35151 - 35876 (-) alpha/beta hydrolase family
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                                                              • APC23281.1
                                                              		 36063 - >36432 (+) alpha/beta hydrolase
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                                                                Biosynthesis information
                                                                Annotation changelog

                                                                Entry version: next

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2024-07-26
                                                                MIBiG v4 annotathon
                                                                • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                Entry version: 2

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2019-10-16
                                                                Migrated from v1.4
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                2019-10-16
                                                                Updated compound(s) information (NPAtlas curation)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                Entry version: 1

                                                                Date
                                                                Changes
                                                                Submitters
                                                                Reviewers
                                                                2018-08-06
                                                                Submitted
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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