LOCUS       BGC0001488             13752 bp    DNA     linear   CON 13-MAR-2015
DEFINITION  Pseudomonas fluorescens WH6 chromosome, whole genome shotgun
            sequence.
ACCESSION   BGC0001488
VERSION     BGC0001488
KEYWORDS    .
SOURCE      Pseudomonas fluorescens WH6
  ORGANISM  Pseudomonas fluorescens WH6
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     A single contig was split into two, AEAZ01000001 and AEAZ01000053.
            Consequently, the first and last contigs are contiguous.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 15:39:57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5551842
            Orig. end    :: 5565594
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..762)
                     /EC_number="2.1.1.144"
                     /codon_start=1
                     /gene="tam"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 78.7; E-value:
                     8.2e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PFWH6_5247"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="EFQ61004.1"
                     /transl_table=11
                     /translation="MTWSAKQYTLFEQQRTRPVRDLVAAIPSTEVQTAVDLGCGPGNST
                     EVLAERFPQARITGLDSSDDMLIDARKRLPTLSFELADIGAWAPAQSFDVILANASLQW
                     LADHATLYPHLVRQLNPGGTLAVQTPDNLEEPAHRLAREVAGAGPWADRIGAVKHNERH
                     TASDYYELLSPRCSSVDVWRTTYLHPLADHAAVVEWFKASALRPYLAPLSDSEKTAFLQ
                     DYQARITQAYPALADGTVLLPFPRLFIIATR"
     subregion       1..13752
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13752
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..762)
                     /gene="tam"
                     /locus_tag="PFWH6_5247"
     gene            complement(806..2260)
                     /gene="ydcR"
                     /locus_tag="PFWH6_5248"
     CDS             complement(806..2260)
                     /NRPS_PKS="Domain: Aminotran_1_2 (105-461). E-value:
                     2.1e-41. Score: 134.1. Matches aSDomain:
                     nrpspksdomains_PFWH6_5248_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="ydcR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 283.4; E-value:
                     4.6e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PFWH6_5248"
                     /product="transcriptional regulator, GntR family"
                     /protein_id="EFQ61005.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.1e-42, bitscore:
                     134.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLYLNLAEFISSRIEQGLYGPGERLPSVRTLSHEHGVSLTTVQQ
                     AYRVLECSGLAIPRPKSGYFVPSDRRVAPLPQMGRPILRPVDISQWDMVQELMRFDQSA
                     DIVQLGCGMPDISAPTLKPLLTAMARISRRSDSTSLQYSHIQGVLALREQIARLSIDSG
                     VRLTPADLIITSGCQEALSTAIRAICSPGDIVAVASPSYHGMMQILKAADLKALEIPSD
                     PVTGINLEALEMALEQWPIKVIQLTANCNNPMGYIMPDERKLKLIRMAQRFDVPIIEDD
                     IYGDLSHRYPRPRSLKSFDEDNRVVLCSSLSKTVAPGLRVGWIAPGRYLPQVLHMKYIG
                     SGATVTQPQLAAAEFIAKGNYLLHLRRMRKQYKRNGDLMSEWVNRYFPAGTRVSQPQGG
                     FTLWVELPGEFDTYALNRLLEAQDVQVANGNIFSAAGKYRNCIRLNFANPPTRKVEMAV
                     QKVGQTVGQLMQMESDNTLTAQQRQP"
     aSDomain        complement(878..1945)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PFWH6_5248_Aminotran_1_2.1"
                     /evalue="2.10E-41"
                     /label="PFWH6_5248_Aminotran_1_2.1"
                     /locus_tag="PFWH6_5248"
                     /protein_end="461"
                     /protein_start="105"
                     /score="134.1"
                     /tool="antismash"
                     /translation="IVQLGCGMPDISAPTLKPLLTAMARISRRSDSTSLQYSHIQGVLA
                     LREQIARLSIDSGVRLTPADLIITSGCQEALSTAIRAICSPGDIVAVASPSYHGMMQIL
                     KAADLKALEIPSDPVTGINLEALEMALEQWPIKVIQLTANCNNPMGYIMPDERKLKLIR
                     MAQRFDVPIIEDDIYGDLSHRYPRPRSLKSFDEDNRVVLCSSLSKTVAPGLRVGWIAPG
                     RYLPQVLHMKYIGSGATVTQPQLAAAEFIAKGNYLLHLRRMRKQYKRNGDLMSEWVNRY
                     FPAGTRVSQPQGGFTLWVELPGEFDTYALNRLLEAQDVQVANGNIFSAAGKYRNCIRLN
                     FANPPTRKVEMAVQKV"
     gene            2568..3575
                     /locus_tag="PFWH6_5249"
     CDS             2568..3575
                     /codon_start=1
                     /locus_tag="PFWH6_5249"
                     /product="hypothetical protein"
                     /protein_id="EFQ61006.1"
                     /transl_table=11
                     /translation="MTARMTLTPQMAEYEQKFTDAGEVRWLPYLMYFHPTDHCSPVVNT
                     DSSGFRYSESLGTNYSVIDGGKNNGPVRLLAGSSTVFGIGASADSWTLASRLTHNDSRG
                     QRWINFGGRSFNSTQELVLFTLNRHHLPRVDEIVLFSGFNNLGLARQPQAYRGEHGAFF
                     NCHQFFDALTPQQPAASHWSLSNLFGKPQEPEQPAPPSMQEQIDYAANLTLQHLDIWRA
                     LAADMGAKLTFILQPLAGWVRETGSAEEEQLFAELDQLGNFTEVYGDILQTSVREAYAQ
                     RLREGAQAMGVGFVDITPLLAEALAPQDWQFVDRIHFTDAGNDLVSKLILDVTR"
     gene            3559..3672
                     /locus_tag="PFWH6_5250"
     CDS             3559..3672
                     /codon_start=1
                     /locus_tag="PFWH6_5250"
                     /product="hypothetical protein"
                     /protein_id="EFQ61007.1"
                     /transl_table=11
                     /translation="MTSLAEKDLHMKSIKKFFLRLFGKKKKKPDSSIYPMF"
     gene            3756..5900
                     /locus_tag="PFWH6_5251"
     CDS             3756..5900
                     /codon_start=1
                     /locus_tag="PFWH6_5251"
                     /product="hypothetical protein"
                     /protein_id="EFQ61008.1"
                     /transl_table=11
                     /translation="MALDPECFLDAEYLDNLLGDDGEPAQLPLLSRQIDAWQLEQASAY
                     AGAAAAAVEQHNARAFAQALAIYSAPLASVLGCWLQGMSAPGVFEDPAQLRLMQLFAHD
                     VGVGYPNASRAHHFNALLGQLQLTTYALAPAQLATLPDLNDDAFELPALLQALSRRSDA
                     FGDELCGVDWALRAVGLCPGWAAMGQLEGLALELGRLDLSAAFPGLEPASLRHISQWVA
                     QRIIEQGEERQARLLRGANWLFGALRRWNARLYNASLTATSPQQAMAHLMQRLARVGAV
                     YHQNYLIEGRSLALWLEDAQHDPLPLLDVLSRSRLIVPGNAKKSLLVTSLVAPTGRMFR
                     IFSEADLNVIRQWIDWLPQAGTTEQLPRQPIDSCAMAARPTTASAADTGHWPQSLREAY
                     FVLQGRALQPTTLKFAHAYVSRWLERSRQSLKTSERQLPEQWGTQVLRGWLLDKHDQNG
                     QQFDDSDPAQIPSREEIVESTLQLAPLTLIDGAWLQGFTDVGLASSHVGYTLFQTYWDE
                     LGNGIEALNHPKIYRDGLREMDFELAPTGSREFAEDPRLYEESFRLPVYWLCLGKLPVT
                     FMPEILGMNLAMELSGVGGSYRSARRFLRHYGFSTAFVDLHNTIDNVSTGHSAWAADAI
                     DAYMRSLTSAEQVAAQWQRVRVGYESLAPMPGKWTSMLRRLGLSSAGDVLPRPARAATS
                     SRYLHHLPITREVLLETHEP"
     gene            5918..6961
                     /gene="strB1"
                     /locus_tag="PFWH6_5252"
     CDS             5918..6961
                     /codon_start=1
                     /gene="strB1"
                     /locus_tag="PFWH6_5252"
                     /product="Inosamine-phosphate amidinotransferase 1"
                     /protein_id="EFQ61009.1"
                     /transl_table=11
                     /translation="MSLVEVHNEWDPLEEMIVGVAHGARVPRPDRGLFALDYSEHHDSP
                     HEIPSGPYPEQLIEEAQEDLDAFAAFLVGHGVTVRRPRETYHAALFGTADWKTDGEYNY
                     CPRDVLLPIGKTIIEAPMALRSRYFEPFAYREHLQAYFASGANWISAPKPELPDSTYRV
                     NPREGSIIANDEPIFDAANVLRMGRDILYLVSRSGNRLGYEWLKRVLGDQYRVHALSGF
                     YDGTHLDTTITLVRPGLVVLNPERIGKDQVPDVFKNWDIIWAPDMVDTGYCWSYPRASI
                     WQGMNFIMVNPSLAVINDQQVPLIRALEKHHVDVAPLKMRHARSLSGGFHCVSVDIRRR
                     GTLEDCR"
     gene            6975..7598
                     /gene="yfiK"
                     /locus_tag="PFWH6_5253"
     CDS             6975..7598
                     /codon_start=1
                     /gene="yfiK"
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score:
                     140.1; E-value: 1.2e-42)"
                     /gene_kind="transport"
                     /locus_tag="PFWH6_5253"
                     /product="transporter, LysE family"
                     /protein_id="EFQ61010.1"
                     /transl_table=11
                     /translation="MQALDYYSIVLFVIATCVTPGPNNVMLMSSGANFGMGRTLRHVAG
                     INIGFPLMLVAVGLGAGAVFRQYPWLHDGLQVIGALYLLFLAYQIASAPTTDLGDKSGK
                     PLGFTAAALFQWVNPKAWVMAVGAVLAYTSPLGSYTVQVFLIALLFFLFGSPCSMVWVF
                     FGQYLRRFLTQPQRLKAFNITMSLVLVVSLIPVLRSLPFAQWWS"
     gene            7689..9530
                     /locus_tag="PFWH6_5254"
     CDS             7689..9530
                     /EC_number="2.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PFWH6_5254"
                     /product="carbamoyl transferase of the NodU/CmcH family"
                     /protein_id="EFQ61011.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 5.7e-92,
                     bitscore: 298.6, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIYVLGISAFYHDSAAALVKDGVPVAAAQEERFTRVRHDPAFPA
                     QAIAYCLDAEGITLADLQAVVYYEDPQEKFSRVISSFASGGIGGARTFINAMPEWIRWK
                     WNVLKFVDEQLEIMGRGKAPRTQASQHHRSHAAAAFYPSPFKNAAVLCIDGIGEWHSTT
                     IWHGQGSQLELKNSISYPHSVGLLYSAMTYYCGFKVDSGEYKLMGLAPYGQPIYADKIR
                     DELINIREDGSFTLNMKYFEYLRGERMVGEAFEALFGGPIRQPESPISQRECDLAASIQ
                     KVTEEVVLGLATAAVKQTGERNLCLAGGVALNCVANGVLSRSGRFDSIWIQPAAGDAGC
                     ALGAALDFAVKHSGRPHLDGNKSDAMSGSLLGPGFGDEEIAQFLLENHYPFTRYDDAGL
                     YDQVASRLADGAVVGWFQGRMEFGPRALGARSILGDARNPEMQRTMNLKIKYRESFRPF
                     APAVLAEDAGNYFDICEKSPYMLMVAPVTDSIKSQQSLQEGGPERGLGSINHIRSQLPA
                     VTHVDLSARVQTVTEENNAPFTYLLRSFKEHTGCSVLVNTSFNVRGEPIVCTPQEAYAC
                     FMRTEMDVLVLGRYVLERPAQPAFVEAVDWRSEIPLD"
     gene            9564..9707
                     /locus_tag="PFWH6_5255"
     CDS             9564..9707
                     /codon_start=1
                     /locus_tag="PFWH6_5255"
                     /product="hypothetical protein"
                     /protein_id="EFQ61012.1"
                     /transl_table=11
                     /translation="MLRFLAFLMFIVVLLPIGLTRSVFHSSRFGRRFHQAPTAWDHSVS
                     NP"
     gene            9734..11053
                     /locus_tag="PFWH6_5256"
     CDS             9734..11053
                     /NRPS_PKS="Domain: Aminotran_3 (18-366). E-value: 4.2e-90.
                     Score: 294.0. Matches aSDomain:
                     nrpspksdomains_PFWH6_5256_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 377.1;
                     E-value: 1.7e-114)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PFWH6_5256"
                     /product="hypothetical protein"
                     /protein_id="EFQ61013.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-91, bitscore:
                     297.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVIYKNLNTSPILAVGGAGVWLEDATGKRYLDTCGGVAVSSLG
                     HGHPRIAAAFEREAKKLAWAHAGSFTTAAAEELAERLVAASGGLARAQFLSGGSEVMEL
                     AMKIAYQYQCERGLPEKSLFISRRQSYHGSTLGTLSISGNPQRQSVFGQLFAAAEFVSP
                     CYAYRDQRPDESEEQYATRLADELDAKIRSLGSENVAAFFAETVVGSTNGAVPAVPGYF
                     RKIKAVCERHDVLLILDEVMAGMGRTGQLFAYADDGIVPDMVAVGKGLAAGYMPISALL
                     ISDQVHSVMARGSGVLGNGQTHVNHPLACAIALEVQQVIEDEDLLAQVRQRGEQLRAWL
                     RESLADLDIVGDVRGRGLFVGVEFVESRATKAPFKGGGAYAAALKQEALQRGLLIYPGS
                     GTVQGTHGNHVLFAPPFITSEGELGQMVERFNAVVRAVAY"
     aSDomain        9788..10831
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PFWH6_5256_Aminotran_3.1"
                     /evalue="4.20E-90"
                     /label="PFWH6_5256_Aminotran_3.1"
                     /locus_tag="PFWH6_5256"
                     /protein_end="366"
                     /protein_start="18"
                     /score="294.0"
                     /tool="antismash"
                     /translation="GAGVWLEDATGKRYLDTCGGVAVSSLGHGHPRIAAAFEREAKKLA
                     WAHAGSFTTAAAEELAERLVAASGGLARAQFLSGGSEVMELAMKIAYQYQCERGLPEKS
                     LFISRRQSYHGSTLGTLSISGNPQRQSVFGQLFAAAEFVSPCYAYRDQRPDESEEQYAT
                     RLADELDAKIRSLGSENVAAFFAETVVGSTNGAVPAVPGYFRKIKAVCERHDVLLILDE
                     VMAGMGRTGQLFAYADDGIVPDMVAVGKGLAAGYMPISALLISDQVHSVMARGSGVLGN
                     GQTHVNHPLACAIALEVQQVIEDEDLLAQVRQRGEQLRAWLRESLADLDIVGDVRGRGL
                     FVGVEFVE"
     gene            11121..11723
                     /locus_tag="PFWH6_5257"
     CDS             11121..11723
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 55;
                     E-value: 9.9e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="PFWH6_5257"
                     /product="hypothetical protein"
                     /protein_id="EFQ61014.1"
                     /transl_table=11
                     /translation="MQTIEPCKDKVLLSVCTMDWCDHGVEFAKTVFSNLEVFCWDPGDP
                     YPYHLDNWEGDWIISYRGDFIFPPSIYKNARKGAINLHPAPPKYRGLGSQHYAIYYNDE
                     TYGSTCHHLAPSVDSGQIINVARFNVAPAETASSLRLHVGAYCLQQFIHLLTDYILLGR
                     PLPVSPENWGERLYKQSELKPWMEKIRAQEPDHRCFK"
     gene            11804..12433
                     /gene="yahN"
                     /locus_tag="PFWH6_5258"
     CDS             11804..12433
                     /codon_start=1
                     /gene="yahN"
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score:
                     111.7; E-value: 5.8e-34)"
                     /gene_kind="transport"
                     /locus_tag="PFWH6_5258"
                     /product="threonine efflux protein"
                     /protein_id="EFQ61015.1"
                     /transl_table=11
                     /translation="MFEFSSFAAALGVYVIGTASPGPGNLAIANTSLNYGRTPGLALAA
                     GVISGSLCWGAMTAAGVSALLMSNTQIILWLKVFGACYLFFLAWKSVRSALAHNATTVA
                     KVREKQTRNLGFYLQGLGIHLTNPKAALTWFTVTTVGLSVNAPAWASFVLVAACALLGF
                     LIFCTYALAFSAHSAEPFFTRTRKSFGLICAAFYSMVAIGFLSSLF"
     gene            12521..13132
                     /gene="yfiK"
                     /locus_tag="PFWH6_5259"
     CDS             12521..13132
                     /codon_start=1
                     /gene="yfiK"
                     /gene_functions="transport (smcogs)
                     SMCOG1116:Homoserine/threonine efflux protein (Score:
                     175.5; E-value: 1.7e-53)"
                     /gene_kind="transport"
                     /locus_tag="PFWH6_5259"
                     /product="transporter, LysE family"
                     /protein_id="EFQ61016.1"
                     /transl_table=11
                     /translation="MSLSFDLMLAFALFAFVTSVTPGPNNAMLLASGVNFGFQRTIPHI
                     LGISSGFLVLVLAVGLGLGAAFTAYPVLYTVLRYAGAAYLLYLAWNIARSGPASEDTEG
                     KGKPLGFWGAAAFQWVNPKAWVMAIGAISTYTPLQGYTMNVVIIATVFALINAPSVGVW
                     AGFGSVLRNVLRNPRWLRMFNFGMAALLVISLYPLLQHTS"
     gene            complement(13237..13752)
                     /gene="ssb"
                     /locus_tag="PFWH6_5260"
     CDS             complement(13237..13752)
                     /codon_start=1
                     /gene="ssb"
                     /locus_tag="PFWH6_5260"
                     /product="single-strand DNA-binding protein"
                     /protein_id="EFQ61017.1"
                     /transl_table=11
                     /translation="MARGVNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDKQT
                     GQKVEKTEWHRVSMFGKVAEIAGEYLRKGSQVYIEGKLQTREWEKDGIKRYTTEIVVDM
                     QGTMQLLGGRPQGDQQGQGGMSNSAPRPQQSRPQPSQQPQRESRPAPQQAAAQPAPDFD
                     SFDDDIPF"
ORIGIN
        1 ttagcgggta gcgatgatga acaggcgcgg gaatggcagc aacaccgtgc catcggccag
       61 ggctgggtag gcctgggtaa tacgcgcctg ataatcctgc aggaacgcgg ttttttcgct
      121 atcgctcagc ggtgcgagat aaggccgcaa cgccgaggcc ttgaaccatt ccaccactgc
      181 cgcgtgatcc gccaaggggt gcaggtaggt ggtgcgccat acgtcgacgc tgctgcagcg
      241 cggactcagc agttcgtagt agtcactcgc ggtatggcgc tcattgtgtt tgaccgcacc
      301 gatcctgtcc gcccacggcc ccgcccccgc aacctcacgc gccagccggt gcgcgggttc
      361 ctcgaggttg tccggcgttt gcaccgccag cgtaccgccg gggttcagtt gcctgaccag
      421 gtgcgggtac agcgtggcgt ggtccgccag ccactgcagg gaagcgttgg ccaggatcac
      481 gtcgaagctt tgcgcagggg cccaggcgcc gatatccgcc agttcgaagc tgagcgtcgg
      541 cagacgcttg cgggcgtcta tcagcatgtc gtcggagctg tccagccccg tgatccgcgc
      601 ctgcggaaaa cgttcggcca gaacttcggt ggaattgcca gggccgcagc ccaggtcaac
      661 agcggtctgc acttcggtgc ttggaatggc cgctaccaag tcgcggacgg ggcgagtgcg
      721 ttgttgttca aatagtgtgt actgcttggc ggaccaggtc attgcggctt tcctttaaaa
      781 cgcagcgcct ttaaaacgca gggcgctaag gctggcgttg ttgcgcggtg agggtgttgt
      841 ccgactccat ctgcatcaac tggccaacgg tctgcccgac cttttgcacg gccatctcga
      901 ccttgcgggt gggcgggttg gcgaaattca agcggatgca attacggtat tttcccgccg
      961 ccgagaaaat attgccattg gccacctgca catcctgggc ttccagcagg cggttgaggg
     1021 cataggtgtc gaactcccca ggcaattcga cccacagggt aaagccaccc tggggctggc
     1081 tgacgcgggt gccggccggg aaatagcggt tgacccactc actcatcagg tcgccgttgc
     1141 gcttgtactg cttgcgcatg cggcgcaggt gcagcaggta gttgcccttg gcgataaatt
     1201 cggccgccgc cagttgcggt tgggtgacgg tggcgccgga gccgatgtat ttcatatgca
     1261 gcacctgggg cagatagcgc ccgggagcga tccagccgac gcgcaggcct ggggccacgg
     1321 ttttggaaag cgaactgcac aacacgaccc ggttgtcctc atcaaaggac ttgagcgagc
     1381 gcgggcgtgg atagcggtgc gacaggtcac cgtagatatc gtcttcaatg atcggcacgt
     1441 cgaagcgctg ggccatgcgg atcagcttga gcttgcgctc gtcgggcatg atgtagccca
     1501 tggggttgtt acagttggcg gtcaattgga tcaccttgat cggccactgc tccagggcca
     1561 tttccaaggc ttccaggttg atgccggtca cagggtcgct ggggatttcc aacgccttga
     1621 gatcggccgc cttgaggatc tgcatcatcc cgtggtagct cggcgaggcg accgccacga
     1681 tgtcgccggg cgagcagatc gcgcggattg cggtggacag cgcttcctgg cagccgctgg
     1741 tgataatcag gtcggccggg gtgaggcgaa cgcccgaatc gatggacagc cgggcgatct
     1801 gttcgcgcaa ggccaatacg ccctggatgt ggctgtattg caggctggtg ctgtcactgc
     1861 gccggctgat acgcgccatc gcggtcagca gcggtttgag ggtcggcgcg ctgatatccg
     1921 gcatgccgca ccccagttgg acgatatcgg cgctttgatc gaagcgcatc agctcctgga
     1981 ccatgtccca ctgagagatg tccaccggcc gcaggatcgg ccggcccatc tgcggcaagg
     2041 gtgccacgcg ccggtccgac ggcacgaaat agcccgactt gggacgcggt atcgccaacc
     2101 ccgaacattc caatacacgg taggcctgtt gcacggtggt caggctgacg ccgtgctcgt
     2161 gactgagggt gcgtacagat ggcaaacgct cgccaggccc gtacaggcct tgctcgatgc
     2221 ggctgctgat gaattcggcg aggttcagat aaagagtcat aagtctgact gtagctgctc
     2281 atctgtggct taagaagtta cagataggca tttttttgaa aaattttcgg ccttaaaagc
     2341 gtatctgtat ttaaaagatt gagttctgct gtatctgcaa tacacaccgt cgccttggga
     2401 tgataggccc cagaacggtg cacagggcct aggacacggt agccgcaaaa taacaaagca
     2461 gcacagtacg caccaatttt aagaaatgcc ctacaaaaca gacgcctgat aattatcaac
     2521 gccaggtgtt ggaaactgcc cagcgaatac caaggggacc cagcgcaatg acggcaagga
     2581 tgacgctcac accgcagatg gccgagtacg aacagaaatt taccgatgcc ggtgaagttc
     2641 gatggttacc ctatttgatg tacttccacc cgactgacca ttgttctccc gtggtcaata
     2701 cagattcgtc cggtttccgt tattccgagt cattgggcac caattattca gtgatcgatg
     2761 gcggcaagaa taacggcccg gtacgcctgt tggcgggcag ctccactgta ttcggcattg
     2821 gcgccagcgc cgacagctgg acgctggcct cgcgcctgac gcacaacgac tcccggggtc
     2881 aacgctggat caatttcggc ggtcgcagtt tcaactccac tcaagaattg gtgctgttca
     2941 ccctgaaccg gcaccacctg ccgcgggtgg acgaaatcgt gctgttctcc gggttcaaca
     3001 accttggcct ggcacgccag ccccaggcct atcggggcga acacggggcg tttttcaact
     3061 gccatcagtt tttcgatgcc ctgacgccgc aacagccggc cgccagccac tggagcctgt
     3121 cgaatctgtt cggcaagcct caggagcccg agcaacccgc gccgccgtcg atgcaggaac
     3181 agatcgacta cgccgccaac ctgactttgc agcatctgga tatctggcgc gccctggcgg
     3241 ccgacatggg ggcgaagctg acattcatcc tgcaaccctt ggccggctgg gtccgcgaga
     3301 ccggcagcgc cgaggaagag caactgtttg ccgaactcga ccagctcggc aacttcaccg
     3361 aggtgtatgg cgacatcctg caaacctcgg tgcgcgaagc ctatgcccag cgcctgcgtg
     3421 aaggggcaca ggcgatgggg gtggggtttg tcgacatcac gccattgctg gccgaggcat
     3481 tggccccgca ggactggcag ttcgtcgacc gtatccactt caccgatgcc ggcaacgacc
     3541 tggtttcaaa actcattctt gacgtcactc gctgaaaagg acttgcacat gaaatccatc
     3601 aaaaagtttt tcctgcgcct gtttggaaaa aagaagaaaa agcctgattc ctccatttat
     3661 ccgatgttct gacgcggcac tgcaaggtaa tggctatgga tggctcggtt ttaacgcggg
     3721 tccccgcaca cgacaggtgg cgcgaactct atcgtttggc gctcgaccct gaatgtttcc
     3781 tggatgcgga gtatctcgac aacctgctgg gtgacgacgg cgagccggcg caattaccgc
     3841 tgctgtcgcg gcagattgac gcgtggcagc tggagcaggc gtcggcgtat gccggtgccg
     3901 cggccgccgc ggtcgaacag cacaacgccc gcgcctttgc ccaggcgctg gccatctatt
     3961 cggcaccgct ggcctcggtg ctgggctgct ggctgcaggg catgagcgcg ccaggggtgt
     4021 ttgaagaccc cgcacagttg cgcttgatgc aattgttcgc ccatgacgtc ggcgtcggtt
     4081 acccgaacgc ctcccgcgcc catcatttca atgcgctgtt ggggcagttg cagttgacga
     4141 cgtacgcctt ggccccggcg caactggcga ccctgccgga cctgaatgac gatgcgttcg
     4201 aactgcccgc gctgttacag gccttgagcc ggcgcagcga tgccttcggc gatgaactct
     4261 gtggtgtcga ttgggccttg cgcgccgtcg ggctgtgccc gggctgggca gccatgggac
     4321 agcttgaagg tctcgcgctg gagttgggac ggctggacct gagcgccgcc ttccctggcc
     4381 tggaaccggc ctcgctgcgc catatcagcc aatgggtcgc gcagcggatc atcgagcagg
     4441 gcgaggaacg ccaggcccgt ttgctgcgcg gcgccaactg gttgttcggc gcgctgcggc
     4501 gctggaatgc gcggctgtat aacgcctcgc tgaccgccac ctcgccccag caggccatgg
     4561 cgcatttgat gcaacgcctg gcccgggttg gcgcggtgta tcaccagaat tacctgatcg
     4621 aaggccgcag cctggcgctg tggcttgaag acgcgcagca cgacccgttg cccttgctgg
     4681 acgtgctgtc gcgcagccgc ctgatcgtgc ctggcaatgc gaaaaaaagc ctgctggtga
     4741 ccagcctggt cgcgccgacc gggcgcatgt tccgcatctt cagtgaggcg gacttgaacg
     4801 tgatccgcca gtggatcgac tggttgcccc aggcgggtac cactgagcaa ctgccgcgtc
     4861 agccgatcga cagttgcgcc atggcggccc gcccgactac agccagcgcg gccgacaccg
     4921 ggcactggcc ccagagcctg cgcgaggcct attttgtctt gcaggggcgc gcgctgcagc
     4981 ccaccaccct gaagttcgcc catgcctatg tgagccgttg gctggagcgc tcgcgccaat
     5041 cgctgaaaac gtccgagcgc caattgcccg agcaatgggg cacccaggtg ctgcgcggct
     5101 ggttgctgga caagcatgac cagaacggcc agcagttcga tgacagcgac ccggcgcaaa
     5161 tccccagccg tgaagaaatc gtcgagtcga ccttgcaact ggcgcccctg acgctgatcg
     5221 acggcgcgtg gctgcaaggc ttcaccgacg tggggctggc gtcgtcccat gtgggctaca
     5281 ccttgttcca gacctattgg gacgaattgg gcaacggcat cgaggcgctc aatcacccga
     5341 agatctaccg cgatggcctg cgggaaatgg atttcgaact ggcgcctacc ggtagccggg
     5401 aatttgccga agacccgcgg ctgtatgagg agtccttccg cctgccggtg tattggctgt
     5461 gcctgggcaa gttgccggtg acgttcatgc ctgaaatcct cggcatgaac ctggcgatgg
     5521 aattatccgg cgtgggcggc agctatcgct cggcacggcg ctttttacgg cactacgggt
     5581 tcagcacggc gttcgtcgat ctgcacaaca ccatcgataa cgtgtccacc gggcactcgg
     5641 cctgggccgc cgatgctatt gatgcgtaca tgcgctcgct gaccagcgcc gagcaggtcg
     5701 ccgcgcaatg gcagcgcgtg cgggtgggct atgagtccct ggcgccgatg ccgggcaagt
     5761 ggacctcgat gctgcgtcga ttgggtcttt cgtccgcagg cgatgtcctt ccgcgtccgg
     5821 cacgtgcagc aacgtcaagc cgctatctgc atcacttgcc gatcacccgg gaagtgctgc
     5881 tggaaaccca cgaaccttaa cgccacgagg aacaattatg tctttggtag aagtgcataa
     5941 cgaatgggac cccctcgagg aaatgatcgt gggtgttgcc catggcgcgc gcgtgcctcg
     6001 accggacagg ggcctgttcg ccctcgacta cagcgagcac cacgactcgc cccacgagat
     6061 tccgtcaggc ccctatcctg aacagttgat cgaagaggcc caggaagatc tggacgcctt
     6121 tgcagccttc ctggtcggtc acggggtgac cgtgcgccgg cccagggaaa cctaccatgc
     6181 cgcgctgttc ggcaccgccg actggaagac cgacggcgaa tacaactact gccccaggga
     6241 tgtcctgctg ccgattggaa agaccatcat tgaagcgccg atggctttac gcagccgtta
     6301 cttcgaaccg tttgcctacc gagaacacct gcaggcgtac ttcgccagcg gcgccaactg
     6361 gatttccgcg cccaagccgg aactgccgga cagcacctac cgggtcaacc cgcgtgaagg
     6421 ctcgatcatc gccaacgatg agccgatctt cgatgcggcc aacgtgctgc gcatgggccg
     6481 cgacattctt tacctggtgt cgcgcagcgg caaccgcctg ggctacgagt ggctcaagcg
     6541 cgtgctcggc gatcaatacc gggtgcacgc cctcagcggc ttctacgacg gtacgcacct
     6601 ggacactacc atcaccctgg tgcgcccggg gctggtggtc ttgaaccccg agcgcatcgg
     6661 caaggatcag gtacctgacg tgttcaagaa ctgggacatc atctgggccc ccgacatggt
     6721 ggacaccggc tactgctggt cgtacccgcg cgcgtcgatc tggcagggca tgaacttcat
     6781 catggtcaac ccgtcgctgg cggtgatcaa cgaccagcag gtcccactga ttcgcgccct
     6841 ggaaaaacac catgtcgatg tggcgccgtt gaagatgcgc catgcgcgca gtttgagcgg
     6901 cggttttcac tgtgtgtccg tcgacattcg tcgacgcggc acgctggaag attgccgttg
     6961 agcaggacgt gagcatgcag gcactggatt actactcgat tgtgttgttc gtgatcgcca
     7021 cctgcgtcac gcctgggccg aacaacgtga tgttgatgtc gtccggcgcc aatttcggca
     7081 tgggtcgcac cttgcgccat gtggccggta tcaatatcgg ctttccactg atgctggtgg
     7141 cggtcgggct gggggccggg gcggtgttcc gccagtaccc ctggctgcac gatggcttgc
     7201 aggtgatcgg cgcgctgtac ctgttgttcc tggcgtacca gatcgccagt gccccgacca
     7261 ccgatctggg tgacaaatca ggcaagcctt tggggttcac cgctgcggcg ttgttccagt
     7321 gggtcaaccc gaaggcctgg gtgatggcgg tgggcgcggt gctggcctac acctcgccct
     7381 tgggttcgta cacggtgcag gtgttcctga ttgcactgtt gttttttttg ttcggttcac
     7441 cgtgctccat ggtctgggtg tttttcgggc agtacctgcg gcgcttcctg acccagccgc
     7501 aacgtttgaa ggcgttcaat atcaccatga gcctggtgct cgtggtgtcc ttgatcccgg
     7561 ttttacgaag cctgccattc gcgcaatggt ggtcttgaaa cgcagagaaa ggttgcccgg
     7621 acgccagcag atcgattggc acaggcaact ccacggattg gcggaatgcg atgaggatgc
     7681 acagttaaat ggctatttat gttttaggga tttctgcctt ctatcacgac agtgcggcgg
     7741 ccctggtcaa ggacggcgtg cccgtcgctg ccgcccagga agagcgcttc acccgcgtgc
     7801 gccacgaccc ggcgttcccg gcccaggcga ttgcctactg cctggacgcc gagggcatca
     7861 ccctggctga cctgcaggca gtggtctact acgaagaccc ccaggaaaaa ttctcccggg
     7921 tgatttcctc gtttgccagc ggtggcatcg gcggcgcacg tacgttcatc aatgcgatgc
     7981 cggaatggat tcgctggaag tggaacgtgc tcaagttcgt cgacgagcaa cttgaaatca
     8041 tgggccgggg caaggcacca cgcacccagg cctcccagca tcaccgttct cacgcggcgg
     8101 cggcgtttta tccctcgccg ttcaagaacg ctgcggtgtt gtgcatcgac ggtatcggcg
     8161 aatggcattc gaccaccatc tggcacggcc agggttcgca acttgaactg aaaaactcga
     8221 tctcctaccc ccattccgta ggcttgctgt attcggccat gacctactat tgcgggttca
     8281 aggtcgactc cggcgagtac aagctgatgg gcctggcgcc gtatggccag ccgatctatg
     8341 ccgacaagat tcgcgacgaa ctgatcaata tccgcgagga cggctcgttc accctgaaca
     8401 tgaagtactt cgagtacctg cgcggcgagc gcatggtggg cgaggccttt gaggcgctgt
     8461 tcggcgggcc gatccgtcag cccgaaagcc cgatctcaca gcgcgagtgc gacttggccg
     8521 catcgattca aaaggtcacc gaggaagtgg tactgggcct ggccaccgcc gcggtcaagc
     8581 agaccggcga gcgcaacctg tgcctggccg gtggcgtggc gttgaactgc gtggccaacg
     8641 gtgtgctcag ccgctcgggg cgtttcgatt cgatctggat ccagccggcg gccggcgatg
     8701 ccggttgtgc cctgggggcg gcgttggatt ttgcggtcaa gcacagcggt cgcccgcact
     8761 tggatggcaa caagtccgat gccatgagcg gcagcctgct ggggccgggt tttggcgatg
     8821 aagaaatcgc ccagttcctg ctggaaaacc actacccctt tacccgctac gacgacgccg
     8881 ggctgtatga ccaggtcgcc agtcgcctgg ccgacggtgc ggtggtgggt tggttccagg
     8941 ggcgcatgga gtttggccca cgggccttgg gcgcgcgttc gattctcggc gatgcgcgca
     9001 accccgagat gcagcgcacc atgaacctga agatcaaata ccgcgagtcg ttccgcccgt
     9061 tcgccccggc cgtgctggcc gaagacgccg gcaactattt cgatatctgc gaaaaaagcc
     9121 cgtacatgtt gatggtcgcg ccggtcaccg actcgatcaa atcccagcag tcgctgcaag
     9181 aaggcggccc cgagcggggc ttgggcagca tcaaccatat tcgctcgcag ttgccggcgg
     9241 tgacccacgt cgacctgtcg gcgcgggtgc aaacggtgac cgaagaaaac aacgcaccgt
     9301 tcacctacct gctgcgcagt ttcaaggagc acaccggctg ctcggtgttg gtcaacacct
     9361 cgttcaacgt gcgtggcgaa ccgatcgtgt gcacgccgca ggaagcgtac gcctgcttca
     9421 tgcgcacgga aatggacgtg ctggttctgg gccgctacgt gcttgagcgc cccgcccagc
     9481 cggccttcgt cgaggccgtt gactggcgca gcgagatccc gctggactga tccccacccc
     9541 cttcactctt tggagctttt accgtgctga gatttcttgc gtttttgatg tttatcgttg
     9601 tgttgctgcc catcgggctg acgcgttcgg tgtttcattc gtcccgtttc gggcggcgct
     9661 ttcaccaggc gccgacggct tgggatcact ccgtaagtaa cccgtaaggc caatcgccca
     9721 aggaaccgcg cgcatgtcaa aagtgattta caaaaatctc aacacctcgc cgatcctggc
     9781 ggtcggcggc gcaggggtgt ggcttgagga tgcaacgggc aaacgctacc tcgacacctg
     9841 cggcggtgtc gcggtgtcga gcctgggcca tggccatccg cgtatcgcag cggcattcga
     9901 gcgcgaagcg aagaaactgg cgtgggcgca cgcgggcagc ttcaccaccg ccgccgccga
     9961 ggaactggcc gaacgcctgg tggcagccag tggcggcctg gcgcgtgcgc agtttttatc
    10021 cggcggctcg gaggtgatgg agctggcgat gaaaatcgct taccagtacc aatgcgaacg
    10081 cggcttgcct gaaaagtcgt tgttcatttc ccgccggcag agctaccacg gcagcaccct
    10141 gggcaccttg agcatctccg gtaacccgca gcgccaatcg gtgtttggtc aactgttcgc
    10201 ggcggccgag tttgtctcgc catgctacgc ctaccgtgat caacggcccg acgaaagcga
    10261 agagcagtac gccacgcgcc tggccgatga actggacgcc aaaattcgca gcctgggcag
    10321 tgaaaacgtc gcggcgttct ttgccgaaac cgtggtgggc tccaccaatg gcgcggtgcc
    10381 tgcggtgccc ggttactttc gcaagatcaa ggccgtgtgc gagcgtcacg atgtgctgct
    10441 gatcctcgat gaggtgatgg ccggcatggg gcgtaccggg cagctgttcg cctatgccga
    10501 cgacggcatc gtgccggaca tggtcgcggt cggcaaaggc ctggcggcgg gctacatgcc
    10561 gatctcggca ctgttgatca gcgaccaggt gcactcggta atggcccgtg gttcaggcgt
    10621 gctgggcaac ggccagaccc acgtcaacca tccgctggcc tgtgccattg ccttggaagt
    10681 gcaacaagtc atcgaggacg aagacctgct ggcgcaagtg cgccaacgcg gtgagcaatt
    10741 gcgcgcctgg ctcagggaaa gcctggctga cctggatatc gtcggtgatg tgcgcgggcg
    10801 cgggctgttc gtgggcgtcg agtttgtcga gagccgcgcc accaaggcgc cgttcaaggg
    10861 cggcggcgcg tatgccgcgg cgctcaagca agaggcgttg cagcgcggcc tgttgatcta
    10921 tcccggcagc ggcaccgtgc agggaacgca cggcaatcat gtgctgtttg caccgccgtt
    10981 tatcaccagc gaaggggagc tggggcaaat ggtcgaacgc ttcaacgcag tggtcagggc
    11041 tgtcgcgtac tagcgacagc gcgggcttga cgggggggcg ggcgttgtca cccacattac
    11101 ctggaaatgg agaagtgaag atgcagacaa tcgagccatg caaggacaag gtcctgctgt
    11161 cggtgtgcac catggactgg tgcgatcacg gcgtggaatt cgccaagacc gtattctcca
    11221 accttgaggt gttttgctgg gacccgggcg atccctatcc ttaccatctg gataactggg
    11281 aaggcgattg gatcatctcc taccgtggcg acttcatttt tccgccgagc atctacaaga
    11341 atgcccgcaa aggcgcgatc aatctgcacc cggcaccgcc caagtaccgg ggcctgggca
    11401 gccagcatta cgcgatctac tacaacgatg aaacctacgg ctcgacctgc catcacctgg
    11461 ccccttcggt ggacagcggg cagatcatca atgtggcgcg tttcaacgtc gcacccgccg
    11521 agacggcttc atcgttgcgc ctgcacgtag gtgcctattg cctgcagcag ttcatccacc
    11581 tgctcaccga ctacatcctg ctgggacggc cactgccggt ctcgccggaa aattggggcg
    11641 agcgcctgta caagcaatcg gaactcaagc cctggatgga gaagatccgc gcccaggagc
    11701 cggatcatcg ttgcttcaaa tagctttttc ttggccgtca cttcaagcca tgggtggctt
    11761 gaagtgctca ctgcgcgctg gcgcgacggg tatgagtgca tctatgtttg agttttcgag
    11821 ttttgcagcg gcactggggg tctacgtgat cggcaccgcc agccctggcc cgggcaacct
    11881 ggccatcgcc aacacctcct tgaactacgg gcgcacaccg ggcctggcgt tggcggccgg
    11941 ggtgatttcc gggtcgttgt gctggggcgc gatgaccgcc gcaggcgtgt cggcgttgtt
    12001 gatgtccaac acccagatca tcctgtggtt aaaagtgttc ggcgcctgct atctgttttt
    12061 cctggcctgg aaatcggtgc gcagtgcgct ggcgcacaac gccacgacgg tagccaaagt
    12121 acgggaaaag cagacgcgca acctgggctt ctatttgcag gggttgggca ttcacctgac
    12181 taaccccaag gcggccttga cctggttcac ggtgaccacc gtgggcctga gcgtcaacgc
    12241 gccggcctgg gccagtttcg tgctggtggc ggcctgtgcg ctattgggtt tcctgatttt
    12301 ctgtacctac gccttagcgt tttccgccca ttcggcagaa ccgtttttca cccggacgcg
    12361 caagtccttc gggctgattt gtgcagcgtt ctactcgatg gttgccattg gttttctcag
    12421 ttcgttgttc tgactccaac tacaagtggc cacactgcac ctgtatcccg cgctgtccgg
    12481 gtggcaggta agcgcgaagg cccgtttcca ggaaatatcc atgtccttgt cgtttgattt
    12541 aatgctggcg tttgctttgt ttgcgtttgt cacttccgtc acccctggcc ccaataacgc
    12601 catgctgttg gcctcgggcg tcaactttgg cttccagcgc accatcccgc acatcctggg
    12661 tatcagctcc gggttcctgg tgctggtatt ggccgtgggg cttgggctgg gtgcagcctt
    12721 taccgcctat ccggtgctct acaccgtgct gcgctatgcg ggcgcggctt acttgctgta
    12781 cctggcatgg aacatcgccc gttccggccc ggcatcagaa gacaccgaag gtaaaggcaa
    12841 gcccctgggg ttctggggcg cagcggcgtt tcagtgggtc aatcccaagg cgtgggtcat
    12901 ggcaattggt gcgatcagca cgtacacgcc cttgcagggc tacaccatga acgtggtgat
    12961 catcgctacg gtgttcgctc tgatcaacgc cccaagcgtg ggggtatggg cggggttcgg
    13021 cagtgtactg cgcaacgtgc tgcgcaaccc gcgctggctg cgcatgttca atttcggcat
    13081 ggcggcgttg ctggtgattt cgctgtatcc gctgctgcag catacgagtt gatcccaggc
    13141 acgcagttgt tacttcacaa aaatctgtgg ccataaaaaa agcgaagcca gattaatggc
    13201 ttcgcttttt tatgggttac ggtactgaaa gctgcgttag aacggaatat cgtcatcaaa
    13261 gctgtcgaaa tccggcgccg gttgcgcagc ggcctgctgg ggcgctggac gcgactcacg
    13321 ctgtggctgc tggcttggct gtggacgcga ctgttgtgga cgcggtgccg agttggacat
    13381 gccaccctgc ccctgttggt cgccctgtgg acggccgccc agcagttgca tggtgccttg
    13441 catgtcgacc acgatctcgg tggtgtaacg cttgatgccg tctttttccc actcgcgggt
    13501 ttgcagtttg ccttcgatgt agacctgcga acctttgcgc aggtactcac cagcgatctc
    13561 tgcaaccttg ccgaacatcg acacacggtg ccattcggtc ttctcgacct tctggccggt
    13621 ctgcttgtcg gtccactgtt cgctggtcgc cagactcagg ttggtcacgg cgttaccgtt
    13681 gggcaagtag cgaacttcgg gatcctggcc gcacgtaccg accaatatga ctttgttaac
    13741 cccacgggcc at
//
