BGC0001489 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001489 (Cladonia uncialis subsp. uncialis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	22,745	6-hydroxymellein	PKS	100%

BGC0001489 - Region 1 - T1PKS

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Location: 1 - 22,745 nt. (total: 22,745 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,746
Label		BGC0001489

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001489	1.00	Polyketide	6-hydroxymellein	Cladonia uncialis subsp. uncialis
BGC0002608	0.38	NRP, Polyketide	ochratoxin A	Aspergillus steynii
BGC0001258	0.37	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906	0.37	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0002154	0.36	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001257	0.36	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002175	0.36	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0000107	0.36	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001284	0.35	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0000156	0.34	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001489	1.00	Polyketide	6-hydroxymellein	Cladonia uncialis subsp. uncialis
BGC0002608	0.70	NRP, Polyketide	ochratoxin A	Aspergillus steynii
BGC0001258	0.69	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906	0.69	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0002154	0.69	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001257	0.69	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002175	0.69	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0000107	0.69	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001284	0.68	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0000156	0.68	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 22745:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AUW31184.1

PKS_AT (902..1200): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 89.1
inactive: 53.0
Methoxymalonyl-CoA: 43.5
Methylmalonyl-CoA: 40.4
fatty_acid: 24.6
Ethylmalonyl-CoA: 17.1
Isobutyryl-CoA: 15.8
2-Methylbutyryl-CoA: 14.7
Propionyl-CoA: 14.3
Benzoyl-CoA: 13.0
3-Methylbutyryl-CoA: 12.3
CHC-CoA: 12.0
Acetyl-CoA: 10.4
trans-1,2-CPDA: 0.0