BGC0001500 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001500 (Actinoallomurus sp. ID145698)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	45,228	High	allocyclinone A/allocyclinone B/allocyclinone C/allocyclinone D	PKS

BGC0001500 - Region 1 - T2PKS

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Location: 1 - 45,228 nt. (total: 45,228 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 45,229
Label		BGC0001500

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase oxygenase

NAI698_09162: flavin reductase domain protein FMN-binding

smcogs: SMCOG1160: flavin reductase domain protein FMN-binding

NAI698_09176: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

NAI698_09184: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

NAI698_09193: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

Transferases: carboxylase halogenase methyltransferase transferase

NAI698_09164: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

NAI698_09170: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

NAI698_09181: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

NAI698_09185: methyltransferase

smcogs: SMCOG1089: methyltransferase

NAI698_09186: conventional flavin-dependent halogenase

halogenases: conventional flavin-dependent halogenase
smcogs: SMCOG1119: halogenase

NAI698_09191: conventional flavin-dependent halogenase

halogenases: conventional flavin-dependent halogenase
smcogs: SMCOG1119: halogenase

Hydrolases: dehalogenase

NAI698_09167: haloalkane dehalogenase

smcogs: SMCOG1262: haloalkane dehalogenase

Lyases: cyclase

NAI698_09169: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

NAI698_09174: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

Ligases: synthase

NAI698_09172: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

NAI698_09173: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001500.3	1.00	PKS	allocyclinone A, allocyclinone B, allocyclinone C, allocyclinone D	Actinoallomurus sp. ID145698
BGC0000231.5	0.63	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001197.5	0.59	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0002276.2	0.59	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0001723.5	0.58	PKS	oviedomycin	Streptomyces antibioticus
BGC0000272.3	0.56	PKS	spore pigment	Streptomyces collinus
BGC0000234.5	0.56	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000217.5	0.55	PKS	daunorubicin	Streptomyces sp.
BGC0002000.4	0.55	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002514.3	0.54	PKS	julichrome Q6.6	Streptomyces sampsonii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001500.3	1.00	PKS	allocyclinone A, allocyclinone B, allocyclinone C, allocyclinone D	Actinoallomurus sp. ID145698
BGC0000231.5	0.63	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001197.5	0.59	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0002276.2	0.59	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0001723.5	0.58	PKS	oviedomycin	Streptomyces antibioticus
BGC0000272.3	0.56	PKS	spore pigment	Streptomyces collinus
BGC0000234.5	0.56	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000217.5	0.55	PKS	daunorubicin	Streptomyces sp.
BGC0002000.4	0.55	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002514.3	0.54	PKS	julichrome Q6.6	Streptomyces sampsonii

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 45228
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 11|12 (Score: 621.7; E-value: 1e-189)
Product class(es):: pentangular polyphenol
Product molecular weight(s):: acetyl-CoA_11: 563 Da
acetyl-CoA_12: 605 Da

NAI698_09164: MET C13O|C17O (Score: 395.8; E-value: 2.9e-121)
NAI698_09169: CYC C4-C21/C2-C23|C2-C19 (Score: 142.3; E-value: 1.2e-44)
NAI698_09171: CYC C5-C18 (Score: 204.3; E-value: 1.3e-63)
NAI698_09172: KS (Score: 732.6; E-value: 2.8e-223)
NAI698_09173: CLF 11|12 (Score: 621.7; E-value: 1e-189)
NAI698_09174: ACP (Score: 50.7; E-value: 3.3e-16); CYC C9-C14 (Score: 256.1; E-value: 2.1e-79)
NAI698_09176: KR C19 (Score: 322.5; E-value: 4.1e-99)
NAI698_09179: OXY (Score: 49.9; E-value: 5.6e-16)
NAI698_09184: KR (Score: 171.0; E-value: 8.8e-53)
NAI698_09186: HAL (Score: 452.8; E-value: 2.8e-138)
NAI698_09191: HAL (Score: 421.5; E-value: 9.1e-129)
NAI698_09193: OXY (Score: 261.9; E-value: 2.8e-80)