BGC0001500: allocyclinone A biosynthetic gene cluster from Actinoallomurus sp. ID145698
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Location: 1 - 45,228 nt. (total: 45,228 nt).
This entry is originally from NCBI GenBank KT996129.1.

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core biosynthetic genes
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transport-related genes
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General
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001500
Short description allocyclinone A biosynthetic gene cluster from Actinoallomurus sp. ID145698
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KT996129.1
via
Compounds
  • allocyclinone A
  • allocyclinone B
  • allocyclinone C
  • allocyclinone D
Species Actinoallomurus sp. ID145698 [taxonomy]
References
Chemical products information
allocyclinone A Evidence: NMR [1]
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C24H14Cl4O8
Chemical database entries
NPAtlas
allocyclinone B Evidence: NMR [1]
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C24H17Cl1O8
Chemical database entries
NPAtlas
allocyclinone C Evidence: NMR [1]
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C24H16Cl2O8
Chemical database entries
NPAtlas
allocyclinone D Evidence: NMR [1]
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C24H15Cl3O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AMX23312.1
  • NAI698_09155
 2242 - 3351 (-) alpha/beta hydrolase family protein
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    • AMX23313.1
    • NAI698_09156
    		 3442 - 6327 (-) transcriptional regulatory protein LuxR
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      • AMX23314.1
      • NAI698_09157
      		 8560 - 9216 (-) hypothetical protein
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        • AMX23315.1
        • NAI698_09160
        		 9732 - 10637 (+) putative DNA-binding protein
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          • AMX23316.1
          • NAI698_09161
          		 10645 - 11514 (-) putative DNA-binding protein
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            • AMX23317.1
            • NAI698_09162
            		 12014 - 12532 (+) putative Oxidoreductase
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              • AMX23318.1
              • NAI698_09163
              		 12564 - 13352 (+) SARP-like transcriptional regulator
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                • AMX23319.1
                • NAI698_09164
                		 13406 - 14434 (+) Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN
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                  • AMX23320.1
                  • NAI698_09165
                  		 14560 - 15516 (-) hypothetical protein
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                    • AMX23321.1
                    • NAI698_09166
                    		 15727 - 16653 (-) response regulator protein VraR
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                      • AMX23322.1
                      • NAI698_09167
                      		 16785 - 17669 (-) 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase
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                        • AMX23323.1
                        • NAI698_09168
                        		 17732 - 18367 (-) hemerythrin HHE cation binding domain protein
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                          • AMX23324.1
                          • NAI698_09169
                          		 18592 - 18918 (+) tetracenomycin polyketide synthesis protein TcmI
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                            • AMX23325.1
                            • NAI698_09170
                            		 18943 - 20556 (+) putative propionyl-CoA carboxylase beta chain 5
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                              • AMX23326.1
                              • NAI698_09171
                              		 20588 - 21004 (+) putative cyclase
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                                • AMX23327.1
                                • NAI698_09172
                                		 21001 - 22275 (+) putative beta-ketoacyl synthase alpha
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                                  • AMX23328.1
                                  • NAI698_09173
                                  		 22268 - 23491 (+) putative chain length factor
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                                    • AMX23329.1
                                    • NAI698_09174
                                    		 23528 - 24259 (+) putative polyketide cyclase
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                                      • AMX23330.1
                                      • NAI698_09175
                                      		 24256 - 24459 (+) hypothetical protein
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                                        • AMX23331.1
                                        • NAI698_09176
                                        		 24493 - 25230 (+) putative acyl carrier protein
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                                          • AMX23332.1
                                          • NAI698_09177
                                          		 25247 - 25573 (+) putative monooxygenase
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                                            • AMX23333.1
                                            • NAI698_09178
                                            		 25570 - 25884 (+) putative monooxygenase
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                                              • AMX23334.1
                                              • NAI698_09179
                                              		 25917 - 27098 (+) FAD-dependent urate hydroxylase
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                                                • AMX23335.1
                                                • NAI698_09180
                                                		 27115 - 27576 (+) putative hydroxylase
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                                                  • AMX23336.1
                                                  • NAI698_09181
                                                  		 27597 - 29348 (+) acetyl-/propionyl-coenzyme A carboxylase alpha chain
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                                                    • AMX23337.1
                                                    • NAI698_09182
                                                    		 29360 - 29845 (-) transcriptional regulator MarR-like
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                                                      • AMX23338.1
                                                      • NAI698_09183
                                                      		 29971 - 31680 (+) multidrug resistance protein stp
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                                                        • AMX23339.1
                                                        • NAI698_09184
                                                        		 31693 - 32460 (+) 3-oxoacyl-acyl-carrier-protein reductase FabG
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                                                          • AMX23340.1
                                                          • NAI698_09185
                                                          		 32608 - 33438 (+) O-methyltransferase
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                                                            • AMX23341.1
                                                            • NAI698_09186
                                                            		 33464 - 35131 (+) putative halogenase
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                                                              • AMX23342.1
                                                              • NAI698_09187
                                                              		 35167 - 35604 (+) putative ester cyclase
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                                                                • AMX23343.1
                                                                • NAI698_09188
                                                                		 35675 - 36181 (+) cupin domain protein
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                                                                  • AMX23344.1
                                                                  • NAI698_09189
                                                                  		 36178 - 36618 (+) putative ester cyclase
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                                                                    • AMX23345.1
                                                                    • NAI698_09190
                                                                    		 36640 - 37947 (+) high-affinity Na(+)/H(+) antiporter NhaS3
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                                                                      • AMX23346.1
                                                                      • NAI698_09191
                                                                      		 37970 - 39652 (+) putative halogenase
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                                                                        • AMX23347.1
                                                                        • NAI698_09192
                                                                        		 39670 - 40113 (+) putative polyketide cyclase
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                                                                          • AMX23348.1
                                                                          • NAI698_09193
                                                                          		 40106 - 41698 (+) putative monooxygenase
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                                                                            Biosynthesis information

                                                                            No biosynthesis information available for this record.

                                                                            Annotation changelog

                                                                            Entry version: 3

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2024-05-13
                                                                            MIBiG v4 annotathon
                                                                            • (ID: WO7I2Z66IEAZGQEL4YNOH36C)
                                                                            • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2019-10-16
                                                                            Migrated from v1.4
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2019-10-16
                                                                            Updated reference publication(s) (MIBiG Annotathon)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2018-08-06
                                                                            Submitted
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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