BGC0001502: amonabactin P 750 biosynthetic gene cluster from Aeromonas hydrophila subsp. hydrophila ATCC 7966
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Location: 2,741,866 - 2,757,479 nt. (total: 15,614 nt).
This entry is originally from NCBI GenBank CP000462.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001502
Short description amonabactin P 750 biosynthetic gene cluster from Aeromonas hydrophila subsp. hydrophila ATCC 7966
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP000462.1
2741866 - 2757479
via
Compounds
  • amonabactin P 750
Species Aeromonas hydrophila subsp. hydrophila ATCC 7966 [taxonomy]
References
Chemical products information
amonabactin P 750 Evidence:
Copy SMILES
C37H46N6O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHA_2473
  • ABK36691.1
2741866 - 2743416 (-) dimodular nonribosomal peptide synthetase
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    • AHA_2474
    • ABK36076.1
    2743413 - 2749607 (-) nonribosomal peptide synthetase
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      • AHA_2475
      • ABK36600.1
      2749724 - 2750473 (-) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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        • AHA_2476
        • ABK39646.1
        2750503 - 2753604 (-) nonribosomal peptide synthetase
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          • AHA_2477
          • ABK39064.1
          2753601 - 2754524 (-) isochorismatase
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            • AHA_2478
            • ABK38474.1
            2754548 - 2756209 (-) 2,3-dihydroxybenzoate-AMP ligase
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              • AHA_2479
              • ABK37486.1
              2756286 - 2757479 (-) isochorismate synthases
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                Biosynthesis information

                Biosynthetic modules

                Name
                Unk01
                Type
                nrps-type1
                Genes
                AHA_2473
                Substrates
                glycine (evidence: Structure-based inference, Sequence-based prediction)
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk02
                Type
                nrps-type1
                Genes
                AHA_2474
                Substrates
                phenylalanine, tryptophan (evidence: Structure-based inference, Sequence-based prediction)
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk03
                Type
                nrps-type1
                Genes
                AHA_2476
                Substrates
                lysine (evidence: Structure-based inference, Sequence-based prediction)
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk04
                Type
                nrps-type1
                Genes
                AHA_2478
                Substrates
                2,3-dihydroxybenzoic acid (evidence: Structure-based inference, Sequence-based prediction)
                Integrated Monomers
                Domains
                adenylation
                Annotation changelog

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                Added NRP substrate specificities
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Switch from RefSeq to GenBank record
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                Migrated from v1.4
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Updated compound(s) information (NPAtlas curation)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                Submitted
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
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