BGC0001503: amycolamycin A biosynthetic gene cluster from Amycolatopsis sp.
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Location: 1 - 89,350 nt. (total: 89,350 nt).
This entry is originally from NCBI GenBank MF990204.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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TTA codons
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Gene details
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General
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Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001503
Short description amycolamycin A biosynthetic gene cluster from Amycolatopsis sp.
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: MF990204.1
Compounds
  • amycolamycin A
  • amycolamycin B
Species Amycolatopsis sp. [taxonomy]
References
Chemical products information
amycolamycin A
(no structure information available)
amycolamycin B
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATV95588.1
7022 - 7396 (+) peptidase inhibitor
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  • ATV95589.1
8727 - 8942 (+) hypothetical protein
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  • ATV95590.1
9039 - 10115 (+) hypothetical protein
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  • ATV95591.1
10001 - 10906 (-) glycosyltransferase
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  • ATV95592.1
11168 - 12190 (-) zinc-containing alcohol dehydrogenase
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  • ATV95593.1
12271 - 13434 (-) aminotransferase
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  • ATV95594.1
13518 - 15116 (-) efflux pump transporter
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  • ATV95595.1
15392 - 16576 (-) oxidoreductase
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  • ATV95596.1
16830 - 17657 (+) aceryltransferase/esterase
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  • ATV95597.1
17683 - 18264 (-) NUDIX domain-containing protein
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  • ATV95598.1
18351 - 19856 (+) NDP-glucose dehydrogenase
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  • ATV95599.1
19853 - 20833 (+) glucuronic acid decarboxylae
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  • ATV95600.1
20886 - 22088 (+) C-methyltransferase
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  • ATV95601.1
22516 - 23970 (-) glycosyltransferase
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  • ATV95602.1
24180 - 24848 (+) O-methyltransferase
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  • ATV95603.1
24869 - 26377 (+) hydroxylase
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  • ATV95604.1
26519 - 27748 (+) cytochrome P450 monooxygenase
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  • ATV95605.1
28079 - 29188 (-) hypothetical protein
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  • ATV95606.1
29209 - 30438 (-) halogenase
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  • ATV95607.1
30480 - 31817 (-) type II condensation domain protein
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  • ATV95608.1
31847 - 32899 (-) p-hydroxymandelate synthase
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  • ATV95609.1
32946 - 33152 (-) MbtH-like protein
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  • ATV95610.1
33163 - 34893 (-) NRPS A-PCP didomain protein
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  • ATV95611.1
35001 - 36332 (-) epoxidase
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  • ATV95612.1
36575 - 37363 (-) NADP-dependent dehydrogenase
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  • ATV95613.1
37591 - 38379 (-) NADP-dependent 3-hydroxy acid dehydrogenase
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  • ATV95614.1
38474 - 39838 (-) RNA polymerase sigma-70 factor
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  • ATV95615.1
40113 - 41153 (+) C-methyltransferase
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  • ATV95616.1
41251 - 46473 (+) 6-methylsalicylic acid synthase
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  • ATV95617.1
46470 - 48128 (+) CoA ligase
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  • ATV95618.1
48400 - 48939 (-) thiol peroxidase
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  • ATV95619.1
48952 - 49407 (-) hypothetical protein
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  • ATV95620.1
49646 - 50113 (+) hypothetical protein
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  • ATV95621.1
50137 - 50613 (+) hypothetical protein
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  • ATV95622.1
50762 - 52531 (+) DNA ligase
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  • ATV95623.1
52528 - 52875 (+) DNA ligase
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  • ATV95624.1
52932 - 53354 (-) apoprotein
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  • ATV95625.1
53548 - 54921 (+) sodium:proton exchanger
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  • ATV95626.1
54968 - 55513 (-) peroxidase
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  • ATV95627.1
55485 - 55943 (-) hypothetical protein
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  • ATV95628.1
55936 - 57279 (-) pyridine nucleotide-disulfide oxidoreductase
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  • ATV95629.1
57311 - 57859 (-) hypothetical protein
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  • ATV95630.1
58051 - 58395 (-) hypothetical protein
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  • ATV95631.1
58503 - 58661 (-) hypothetical protein
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  • ATV95632.1
58840 - 59025 (+) hypothetical protein
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  • ATV95633.1
59101 - 59322 (-) acetyl-CoA carboxylase
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  • ATV95634.1
59339 - 61042 (-) methylmalonyl-CoA carboxyltransferase
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  • ATV95635.1
61039 - 61254 (-) hypothetical protein
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  • ATV95636.1
61251 - 62330 (-) NAD-dependent epimerase/dehydratase
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  • ATV95637.1
62346 - 62918 (-) FAD-dependent monooxygenase
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  • ATV95638.1
62920 - 63369 (-) Thioesterase
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  • ATV95639.1
63372 - 69191 (-) type I PKS
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  • ATV95640.1
69443 - 70237 (-) hypothetical protein
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  • ATV95641.1
70454 - 71053 (-) alkylhydroperoxidase like protein
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  • ATV95642.1
71029 - 71595 (-) alkyhydroperoxidase
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  • ATV95643.1
71595 - 73247 (-) Oxidoreductase
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  • ATV95644.1
73244 - 73825 (-) Regulatory
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  • ATV95645.1
73861 - 75237 (-) P450 hydroxylase
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  • ATV95646.1
75234 - 76238 (-) hypothetical protein
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  • ATV95647.1
76240 - 78213 (-) hypothetical protein
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  • ATV95648.1
78210 - 79193 (-) hypothetical protein
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  • ATV95649.1
79300 - 80295 (-) hypothetical protein
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  • ATV95650.1
80321 - 81241 (-) regulatory protein
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  • ATV95651.1
81745 - 82581 (+) transcriptional regulator
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  • ATV95652.1
82634 - 83329 (+) HxlR family transcriptional regulator
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  • ATV95653.1
83427 - 84638 (-) RNA polymerase sigma factor
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  • ATV95654.1
84635 - 85024 (-) hypothetical protein
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  • ATV95655.1
85153 - 85854 (+) hypothetical protein
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  • ATV95656.1
85858 - 86478 (-) tRNA threonylcarbamoyl adenosine modification protein
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  • ATV95657.1
86621 - 86932 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added AMP domain substrate specificities
Detailed domain annotation
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