BGC0001503: amycolamycin A biosynthetic gene cluster from Amycolatopsis sp.
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Location: 1 - 89,350 nt. (total: 89,350 nt).
This entry is originally from NCBI GenBank MF990204.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001503
Short description amycolamycin A biosynthetic gene cluster from Amycolatopsis sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MF990204.1
via
Compounds
  • amycolamycin A
  • amycolamycin B
Species Amycolatopsis sp. [taxonomy]
References
Chemical products information
amycolamycin A Evidence:
(no structure information available)
amycolamycin B Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATV95588.1
 7022 - 7396 (+) peptidase inhibitor
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    • ATV95589.1
    		 8727 - 8942 (+) hypothetical protein
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      • ATV95590.1
      		 9039 - 10115 (+) hypothetical protein
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        • ATV95591.1
        		 10001 - 10906 (-) glycosyltransferase
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          • ATV95592.1
          		 11168 - 12190 (-) zinc-containing alcohol dehydrogenase
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            • ATV95593.1
            		 12271 - 13434 (-) aminotransferase
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              • ATV95594.1
              		 13518 - 15116 (-) efflux pump transporter
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                • ATV95595.1
                		 15392 - 16576 (-) oxidoreductase
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                  • ATV95596.1
                  		 16830 - 17657 (+) aceryltransferase/esterase
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                    • ATV95597.1
                    		 17683 - 18264 (-) NUDIX domain-containing protein
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                      • ATV95598.1
                      		 18351 - 19856 (+) NDP-glucose dehydrogenase
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                        • ATV95599.1
                        		 19853 - 20833 (+) glucuronic acid decarboxylae
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                          • ATV95600.1
                          		 20886 - 22088 (+) C-methyltransferase
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                            • ATV95601.1
                            		 22516 - 23970 (-) glycosyltransferase
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                              • ATV95602.1
                              		 24180 - 24848 (+) O-methyltransferase
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                                • ATV95603.1
                                		 24869 - 26377 (+) hydroxylase
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                                  • ATV95604.1
                                  		 26519 - 27748 (+) cytochrome P450 monooxygenase
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                                    • ATV95605.1
                                    		 28079 - 29188 (-) hypothetical protein
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                                      • ATV95606.1
                                      		 29209 - 30438 (-) halogenase
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                                        • ATV95607.1
                                        		 30480 - 31817 (-) type II condensation domain protein
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                                          • ATV95608.1
                                          		 31847 - 32899 (-) p-hydroxymandelate synthase
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                                            • ATV95609.1
                                            		 32946 - 33152 (-) MbtH-like protein
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                                              • ATV95610.1
                                              		 33163 - 34893 (-) NRPS A-PCP didomain protein
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                                                • ATV95611.1
                                                		 35001 - 36332 (-) epoxidase
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                                                  • ATV95612.1
                                                  		 36575 - 37363 (-) NADP-dependent dehydrogenase
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                                                    • ATV95613.1
                                                    		 37591 - 38379 (-) NADP-dependent 3-hydroxy acid dehydrogenase
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                                                      • ATV95614.1
                                                      		 38474 - 39838 (-) RNA polymerase sigma-70 factor
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                                                        • ATV95615.1
                                                        		 40113 - 41153 (+) C-methyltransferase
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                                                          • ATV95616.1
                                                          		 41251 - 46473 (+) 6-methylsalicylic acid synthase
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                                                            • ATV95617.1
                                                            		 46470 - 48128 (+) CoA ligase
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                                                              • ATV95618.1
                                                              		 48400 - 48939 (-) thiol peroxidase
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                                                                • ATV95619.1
                                                                		 48952 - 49407 (-) hypothetical protein
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                                                                  • ATV95620.1
                                                                  		 49646 - 50113 (+) hypothetical protein
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                                                                    • ATV95621.1
                                                                    		 50137 - 50613 (+) hypothetical protein
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                                                                      • ATV95622.1
                                                                      		 50762 - 52531 (+) DNA ligase
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                                                                        • ATV95623.1
                                                                        		 52528 - 52875 (+) DNA ligase
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                                                                          • ATV95624.1
                                                                          		 52932 - 53354 (-) apoprotein
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                                                                            • ATV95625.1
                                                                            		 53548 - 54921 (+) sodium:proton exchanger
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                                                                              • ATV95626.1
                                                                              		 54968 - 55513 (-) peroxidase
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                                                                                • ATV95627.1
                                                                                		 55485 - 55943 (-) hypothetical protein
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                                                                                  • ATV95628.1
                                                                                  		 55936 - 57279 (-) pyridine nucleotide-disulfide oxidoreductase
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                                                                                    • ATV95629.1
                                                                                    		 57311 - 57859 (-) hypothetical protein
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                                                                                      • ATV95630.1
                                                                                      		 58051 - 58395 (-) hypothetical protein
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                                                                                        • ATV95631.1
                                                                                        		 58503 - 58661 (-) hypothetical protein
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                                                                                          • ATV95632.1
                                                                                          		 58840 - 59025 (+) hypothetical protein
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                                                                                            • ATV95633.1
                                                                                            		 59101 - 59322 (-) acetyl-CoA carboxylase
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                                                                                              • ATV95634.1
                                                                                              		 59339 - 61042 (-) methylmalonyl-CoA carboxyltransferase
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                                                                                                • ATV95635.1
                                                                                                		 61039 - 61254 (-) hypothetical protein
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                                                                                                  • ATV95636.1
                                                                                                  		 61251 - 62330 (-) NAD-dependent epimerase/dehydratase
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                                                                                                    • ATV95637.1
                                                                                                    		 62346 - 62918 (-) FAD-dependent monooxygenase
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                                                                                                      • ATV95638.1
                                                                                                      		 62920 - 63369 (-) Thioesterase
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                                                                                                        • ATV95639.1
                                                                                                        		 63372 - 69191 (-) type I PKS
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                                                                                                          • ATV95640.1
                                                                                                          		 69443 - 70237 (-) hypothetical protein
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                                                                                                            • ATV95641.1
                                                                                                            		 70454 - 71053 (-) alkylhydroperoxidase like protein
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                                                                                                              • ATV95642.1
                                                                                                              		 71029 - 71595 (-) alkyhydroperoxidase
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                                                                                                                • ATV95643.1
                                                                                                                		 71595 - 73247 (-) Oxidoreductase
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                                                                                                                  • ATV95644.1
                                                                                                                  		 73244 - 73825 (-) Regulatory
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                                                                                                                    • ATV95645.1
                                                                                                                    		 73861 - 75237 (-) P450 hydroxylase
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                                                                                                                      • ATV95646.1
                                                                                                                      		 75234 - 76238 (-) hypothetical protein
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                                                                                                                        • ATV95647.1
                                                                                                                        		 76240 - 78213 (-) hypothetical protein
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                                                                                                                          • ATV95648.1
                                                                                                                          		 78210 - 79193 (-) hypothetical protein
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                                                                                                                            • ATV95649.1
                                                                                                                            		 79300 - 80295 (-) hypothetical protein
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                                                                                                                              • ATV95650.1
                                                                                                                              		 80321 - 81241 (-) regulatory protein
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                                                                                                                                • ATV95651.1
                                                                                                                                		 81745 - 82581 (+) transcriptional regulator
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                                                                                                                                  • ATV95652.1
                                                                                                                                  		 82634 - 83329 (+) HxlR family transcriptional regulator
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                                                                                                                                    • ATV95653.1
                                                                                                                                    		 83427 - 84638 (-) RNA polymerase sigma factor
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                                                                                                                                      • ATV95654.1
                                                                                                                                      		 84635 - 85024 (-) hypothetical protein
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                                                                                                                                        • ATV95655.1
                                                                                                                                        		 85153 - 85854 (+) hypothetical protein
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                                                                                                                                          • ATV95656.1
                                                                                                                                          		 85858 - 86478 (-) tRNA threonylcarbamoyl adenosine modification protein
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                                                                                                                                            • ATV95657.1
                                                                                                                                            		 86621 - 86932 (+) hypothetical protein
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                                                                                                                                              Biosynthesis information

                                                                                                                                              No biosynthesis information available for this record.

                                                                                                                                              Annotation changelog

                                                                                                                                              Entry version: 3

                                                                                                                                              Date
                                                                                                                                              Changes
                                                                                                                                              Submitters
                                                                                                                                              Reviewers
                                                                                                                                              2022-09-15
                                                                                                                                              Added AMP domain substrate specificities
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                                              Entry version: 2

                                                                                                                                              Date
                                                                                                                                              Changes
                                                                                                                                              Submitters
                                                                                                                                              Reviewers
                                                                                                                                              2019-10-16
                                                                                                                                              Migrated from v1.4
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                                              Entry version: 1

                                                                                                                                              Date
                                                                                                                                              Changes
                                                                                                                                              Submitters
                                                                                                                                              Reviewers
                                                                                                                                              2018-08-06
                                                                                                                                              Submitted
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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