BGC0001506 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001506 (Streptomyces sp. NRRL S-146)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lassopeptide	1	15,863	High	anantin B1/anantin B2	ribosomal:RiPP

BGC0001506 - Region 1 - lassopeptide

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Location: 1 - 15,863 nt. (total: 15,863 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lasso peptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,864
Label		BGC0001506

Tailoring functions

Hydrolases: hydrolase

IH29_RS50070: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001506.5	1.00	ribosomal	anantin B1, anantin B2	Streptomyces sp. NRRL S-146
BGC0001507.3	0.82	ribosomal	anantin C	Streptomyces olindensis
BGC0002053.3	0.64	ribosomal	ulleungdin	Streptomyces sp.
BGC0001307.3	0.61	ribosomal	chaxapeptin	Streptomyces leeuwenhoekii
BGC0001539.4	0.60	ribosomal	cattlecin	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0002074.2	0.60	ribosomal	huascopeptin	Streptomyces huasconensis
BGC0001548.4	0.60	ribosomal	citrulassin A	Streptomyces albulus
BGC0001781.4	0.59	ribosomal	sphaericin	Planomonospora sphaerica
BGC0001493.5	0.57	ribosomal	achromosin	Streptomyces achromogenes subsp. achromogenes
BGC0001552.3	0.57	ribosomal	citrulassin F	Streptomyces avermitilis MA-4680 = NBRC 14893

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001506.5	1.00	ribosomal	anantin B1, anantin B2	Streptomyces sp. NRRL S-146
BGC0001507.3	0.82	ribosomal	anantin C	Streptomyces olindensis
BGC0002053.3	0.64	ribosomal	ulleungdin	Streptomyces sp.
BGC0001307.3	0.61	ribosomal	chaxapeptin	Streptomyces leeuwenhoekii
BGC0001539.4	0.60	ribosomal	cattlecin	Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0002074.2	0.60	ribosomal	huascopeptin	Streptomyces huasconensis
BGC0001548.4	0.60	ribosomal	citrulassin A	Streptomyces albulus
BGC0001781.4	0.59	ribosomal	sphaericin	Planomonospora sphaerica
BGC0001493.5	0.57	ribosomal	achromosin	Streptomyces achromogenes subsp. achromogenes
BGC0001552.3	0.57	ribosomal	citrulassin F	Streptomyces avermitilis MA-4680 = NBRC 14893

Similar known clusters from MIBiG 4.0

Lasso peptide predictions

Lassopeptide(s) for allorf_05916_06104

allorf_05916_06104

Leader:

MQWVADRLPLVTGGDVVDEQIELTTAEPYAPPTLTEVGEFNEDTL

Full core:

GFIGWGNDIFGHYSGGF

Putative macrolactam:

GFIGWGND

antiSMASH-DB 4.0 matches for allorf_05916_06104

100.0%

NZ_BMSE01000003.1and 2 others:

NZ_JACHGV010000006.1 Lassopeptides: HNR57_RS21035_lassopeptideNZ_KZ671966.1 Lassopeptides: BV882_RS06405_lassopeptide

Lassopeptides: IE153_RS10035_lassopeptide

GFIGWGNDIFGHYSGGF

94.1%

NZ_AP024135.1and 1 other:

NZ_CP011799.1 Lassopeptides: QR97_RS33380_lassopeptide

Lassopeptides: K6K39_RS32965_lassopeptide

GFIGWGNDIFGHYSGGF

GFIGWG DIFGHYSGGF

GFIGWGKDIFGHYSGGF

94.1%

NZ_CP026121.1and 1 other:

NZ_CP075896.1 Lassopeptides: KJK29_RS31770_lassopeptide

Lassopeptides: C1703_RS06295_lassopeptide

GFIGWGNDIFGHYSGGF

GFIGWGNDIFGHYSG F

GFIGWGNDIFGHYSGDF

with 5 more sequence matches

88.2%

NZ_JACHJK010000012.1:

Lassopeptides: FHS34_RS30310_lassopeptide

GFIGWGNDIFGHYSGGF

GFIGWG DIFGHY GGF

GFIGWGKDIFGHYGGGF

76.5%

NZ_AP026073.1and 12 others:

NZ_BBNO01000002.1 Lassopeptides: TU31_RS37835_lassopeptideNZ_BNCA01000014.1 Lassopeptides: IE314_RS18405_lassopeptideNZ_CP007699.2 Lassopeptides: T261_RS42170_lassopeptideNZ_CP023691.1 Lassopeptides: CP981_RS21655_lassopeptideNZ_CP029042.1 Lassopeptides: DDE74_RS22295_lassopeptideNZ_CP029541.1 Lassopeptides: DKG71_RS23270_lassopeptideNZ_CP049782.1 Lassopeptides: G7Z12_RS16230_lassopeptideNZ_CP050976.1 Lassopeptides: HEP86_RS22775_lassopeptideNZ_CP102609.1 Lassopeptides: NUT86_RS23110_lassopeptideNZ_CP114202.1 Lassopeptides: STRLI_RS17465_lassopeptideNZ_CP114203.1 Lassopeptides: STRNI_RS19305_lassopeptideNZ_JAPKNL010000006.1 Lassopeptides: OSI21_RS10415_lassopeptide

Lassopeptides: HEK616_RS15635_lassopeptide

GFIGWGNDIFGHYSG

GFIGWG DIFGHY G

GFIGWGKDIFGHYGG

35.3%

NZ_CP086322.1:

Lassopeptides: K9S39_RS27710_lassopeptide

GFIGWGNDIFG

G +GW +D FG

GLVGWHHDAFG

19.4%

NZ_CP035758.1:

Lanthipeptides: EPA93_RS48405_lanthipeptide

WGNDIFGHY

WGN GHY

WGNTCTGHY

10.6%

NZ_BNBI01000017.1:

Lanthipeptides: allorf_050255_050446_lanthipeptide

IGWGNDIFGHYSGG

+ W + GH GG

VAWPVQMPGHRRGG

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lasso peptides

Core peptide predictions

allorf_05916_06104 - Class II: Cleavage pHMM score: 3.30; RODEO score: 17; Monoisotopic mass: 1811.8 Da; Molecular weight: 1812.9 Da; Number of bridges: 0