BGC0001512 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001512 (Streptomyces sp)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	19,484	High	BE-24566B	PKS

BGC0001512 - Region 1 - T2PKS

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Location: 1 - 19,484 nt. (total: 19,484 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 19,485
Label		BGC0001512

Tailoring functions

Oxidoreductases: dehydrogenase oxygenase

AbxL: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

abxE: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: halogenase methyltransferase

abxH: conventional flavin-dependent halogenase

halogenases: conventional flavin-dependent halogenase
smcogs: SMCOG1119: halogenase

abxJ: methyltransferase

smcogs: SMCOG1089: methyltransferase

abxM: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

abxN: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

abxQ: methyltransferase

smcogs: SMCOG1089: methyltransferase

Lyases: cyclase

abxC: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

abxD: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

Ligases: synthase

abxK: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

abxP: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001512.5	1.00	PKS	BE-24566B	Streptomyces sp.
BGC0002341.2	0.77	other (other)	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0002608.2	0.76	NRPS, PKS	ochratoxin A	Aspergillus steynii
BGC0001366.5	0.69	PKS	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2
BGC0001513.3	0.69	PKS	anthrabenzoxocinone	Actinobacteria bacterium
BGC0002426.3	0.68	NRPS	deschlorosvetamycin A, svetamycin H, svetamycin A	Streptomyces sp.
BGC0000272.3	0.62	PKS	spore pigment	Streptomyces collinus
BGC0000231.5	0.61	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000215.5	0.60	PKS	curamycin	Streptomyces cyaneus
BGC0001723.5	0.57	PKS	oviedomycin	Streptomyces antibioticus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001512.5	1.00	PKS	BE-24566B	Streptomyces sp.
BGC0002341.2	0.77	other (other)	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0002608.2	0.76	NRPS, PKS	ochratoxin A	Aspergillus steynii
BGC0001366.5	0.69	PKS	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2
BGC0001513.3	0.69	PKS	anthrabenzoxocinone	Actinobacteria bacterium
BGC0002426.3	0.68	NRPS	deschlorosvetamycin A, svetamycin H, svetamycin A	Streptomyces sp.
BGC0000272.3	0.62	PKS	spore pigment	Streptomyces collinus
BGC0000231.5	0.61	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000215.5	0.60	PKS	curamycin	Streptomyces cyaneus
BGC0001723.5	0.57	PKS	oviedomycin	Streptomyces antibioticus

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 19484
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 11|12 (Score: 676.9; E-value: 1.8e-206)
Product class(es):: pentangular polyphenol
Product molecular weight(s):: acetyl-CoA_11: 524 Da
acetyl-CoA_12: 567 Da

AbxL: OXY (Score: 237.7; E-value: 6.1e-73)
abxC: CYC C9-C14 (Score: 244.5; E-value: 7.5e-76)
abxD: CYC C4-C21/C2-C23|C2-C19 (Score: 137.3; E-value: 4e-43)
abxE: KR (Score: 178.6; E-value: 4.1e-55)
abxH: HAL (Score: 419.1; E-value: 5e-128)
abxK: CLF 11|12 (Score: 676.9; E-value: 1.8e-206)
abxM: MET C6|C8 (Score: 472.1; E-value: 1.9e-144)
abxN: MET (Score: 170.9; E-value: 9.1e-53)
abxP: KS (Score: 736.3; E-value: 2.2e-224)
abxR: CYC C5-C18 (Score: 209.3; E-value: 3.6e-65)
abxS: ACP (Score: 67.8; E-value: 1.4e-21)