BGC0001515: aspercryptins biosynthetic gene cluster from Aspergillus nidulans FGSC A4
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Location: 74,783 - 138,817 nt. (total: 64,035 nt).
This entry is originally from NCBI GenBank BN001302.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001515
Short description aspercryptins biosynthetic gene cluster from Aspergillus nidulans FGSC A4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
BN001302.1
74783 - 138817
via
Compounds
  • aspercryptins
Species Aspergillus nidulans FGSC A4 [taxonomy]
References
Chemical products information
aspercryptins Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ANIA_07872
  • CBF73428.1
 74783 - 76663 (-) Putative Zn(II)2Cys6 transcription factor (Eurofung)
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    • ANIA_11582
    • CBF73430.1
    		 80059 - 80638 (-) hypothetical protein
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      • ANIA_07873
      • CBF73431.1
      		 81081 - 87580 (-) fatty acid synthase beta subunit, putative (JCVI)
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        • ANIA_07874
        • CBF73433.1
        		 88455 - 89465 (+) conserved hypothetical protein
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          • ANIA_07875
          • CBF73435.1
          		 89712 - 90235 (-) conserved hypothetical protein
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            • ANIA_07876
            • CBF73436.1
            		 90860 - 92186 (+) branched-chain amino-acid transaminase, putative (Eurofung)
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              • ANIA_07877
              • CBF73438.1
              		 92459 - 93702 (-) RTA1 domain protein, putative (AFU_orthologue; AFUA_2G17810)
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                • ANIA_07878
                • CBF73440.1
                		 94271 - 95507 (+) hypothetical branched-chain amino-acid transaminase, cytosolic (Eurofung)
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                  • ANIA_07879
                  • CBF73441.1
                  		 95818 - 100916 (-) ABC transporter (Eurofung)
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                    • ANIA_07880
                    • CBF73444.1
                    		 102018 - 107632 (+) fatty acid synthase subunit alpha, putative (JCVI)
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                      • ANIA_07881
                      • CBF73446.1
                      		 107800 - 109644 (-) cytochrome P450, putative (Eurofung)
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                        • ANIA_11028
                        • CBF73447.1
                        		 110306 - 111442 (+) conserved hypothetical protein
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                          • ANIA_11031
                          • CBF73449.1
                          		 112569 - 114553 (+) MFS multidrug transporter, putative (AFU_orthologue; AFUA_5G12740)
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                            • ANIA_07883
                            • CBF73451.1
                            		 115074 - 115775 (-) conserved hypothetical protein
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                              • ANIA_07884
                              • CBF73453.1
                              		 116874 - 138684 (+) nonribosomal peptide synthase, putative (JCVI)
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                                Biosynthesis information

                                Biosynthetic modules

                                Name
                                Unk01
                                Type
                                nrps-type1
                                Genes
                                ANIA_07884
                                Substrates
                                serine, alanine (evidence: Structure-based inference, Feeding study, Homology)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk02
                                Type
                                nrps-type1
                                Genes
                                ANIA_07884
                                Substrates
                                threonine, D-allo-threonine (evidence: Structure-based inference, Feeding study, Homology)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk03
                                Type
                                nrps-type1
                                Genes
                                ANIA_07884
                                Substrates
                                isoleucine, valine (evidence: Structure-based inference, Feeding study, Homology)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk04
                                Type
                                nrps-type1
                                Genes
                                ANIA_07884
                                Substrates
                                2S-amino-octanoic-acid (evidence: Structure-based inference, Knock-out studies)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk05
                                Type
                                nrps-type1
                                Genes
                                ANIA_07884
                                Substrates
                                asparagine (evidence: Structure-based inference, Homology)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk06
                                Type
                                nrps-type1
                                Genes
                                ANIA_07884
                                Substrates
                                2S-amino-dodecanoic acid, 2S-amino-decanoic acid (evidence: Structure-based inference, Knock-out studies)
                                Integrated Monomers
                                Domains
                                adenylation
                                Annotation changelog

                                Entry version: 3

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Added NRP substrate specificities
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Migrated from v1.4
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2018-08-06
                                Submitted
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                Detailed domain annotation
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