BGC0001515 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001515 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	64,035	aspercryptins	NRPS:Type I	100%

BGC0001515 - Region 1 - NRPS

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Location: 1 - 64,035 nt. (total: 64,035 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 64,036
Label		BGC0001515

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001515	0.84	NRP	aspercryptins	Aspergillus nidulans FGSC A4
BGC0001261	0.32	NRP	AM-toxin	Alternaria alternata
BGC0002157	0.32	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002242	0.29	NRP	oxepinamide D	Aspergillus ustus
BGC0001545	0.27	NRP	chrysogine	Fusarium graminearum PH-1
BGC0002437	0.27	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0001517	0.27	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0002518	0.27	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001240	0.27	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001166	0.27	NRP	HC-toxin	Alternaria jesenskae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001515	1.00	NRP	aspercryptins	Aspergillus nidulans FGSC A4
BGC0002242	0.66	NRP	oxepinamide D	Aspergillus ustus
BGC0001261	0.65	NRP	AM-toxin	Alternaria alternata
BGC0002157	0.65	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002208	0.63	NRP	oxepinamide F	Aspergillus ustus
BGC0002670	0.63	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0001768	0.61	NRP	sansalvamide	[Nectria] haematococca mpVI 77-13-4
BGC0001545	0.61	NRP	chrysogine	Fusarium graminearum PH-1
BGC0002437	0.61	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0001517	0.60	NRP	asperphenamate	Aspergillus terreus NIH2624

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 22091 - 64035:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ser - D-Thr - Ile - X - Asn - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ANIA_07873

PKS_AT (1727..1929): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ANIA_07884

Search NORINE for peptide: strict or relaxed

AMP-binding (256..652): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A