BGC0001515: aspercryptins biosynthetic gene cluster from Aspergillus nidulans FGSC A4
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Location: 74,783 - 138,817 nt. (total: 64,035 nt).
This entry is originally from NCBI GenBank BN001302.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001515
Short description aspercryptins biosynthetic gene cluster from Aspergillus nidulans FGSC A4
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: BN001302.1
Compounds
  • aspercryptins
Species Aspergillus nidulans FGSC A4 [taxonomy]
References
Chemical products information
aspercryptins
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ANIA_07872
  • CBF73428.1
 74783 - 76663 (-) Putative Zn(II)2Cys6 transcription factor (Eurofung)
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  • ANIA_11582
  • CBF73430.1
 80059 - 80638 (-) hypothetical protein
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  • ANIA_07873
  • CBF73431.1
 81081 - 87580 (-) fatty acid synthase beta subunit, putative (JCVI)
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  • ANIA_07874
  • CBF73433.1
 88455 - 89465 (+) conserved hypothetical protein
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  • ANIA_07875
  • CBF73435.1
 89712 - 90235 (-) conserved hypothetical protein
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  • ANIA_07876
  • CBF73436.1
 90860 - 92186 (+) branched-chain amino-acid transaminase, putative (Eurofung)
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  • ANIA_07877
  • CBF73438.1
 92459 - 93702 (-) RTA1 domain protein, putative (AFU_orthologue; AFUA_2G17810)
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  • ANIA_07878
  • CBF73440.1
 94271 - 95507 (+) hypothetical branched-chain amino-acid transaminase, cytosolic (Eurofung)
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  • ANIA_07879
  • CBF73441.1
 95818 - 100916 (-) ABC transporter (Eurofung)
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  • ANIA_07880
  • CBF73444.1
 102018 - 107632 (+) fatty acid synthase subunit alpha, putative (JCVI)
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  • ANIA_07881
  • CBF73446.1
 107800 - 109644 (-) cytochrome P450, putative (Eurofung)
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  • ANIA_11028
  • CBF73447.1
 110306 - 111442 (+) conserved hypothetical protein
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  • ANIA_11031
  • CBF73449.1
 112569 - 114553 (+) MFS multidrug transporter, putative (AFU_orthologue; AFUA_5G12740)
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  • ANIA_07883
  • CBF73451.1
 115074 - 115775 (-) conserved hypothetical protein
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  • ANIA_07884
  • CBF73453.1
 116874 - 138684 (+) nonribosomal peptide synthase, putative (JCVI)
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ANIA_07884
Module ?
Specificity: serine / alanine
Evidence for specificity:
  • Structure-based inference
  • Feeding study
  • Homology
Module ?
Specificity: threonine / D-allo-threonine
Evidence for specificity:
  • Structure-based inference
  • Feeding study
  • Homology
Module ?
Specificity: isoleucine / valine
Evidence for specificity:
  • Structure-based inference
  • Feeding study
  • Homology
Module ?
Specificity: 2S-amino-octanoic-acid
Evidence for specificity:
  • Structure-based inference
  • Knock-out studies
Module ?
Specificity: asparagine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: 2S-amino-dodecanoic acid / 2S-amino-decanoic acid
Evidence for specificity:
  • Structure-based inference
  • Knock-out studies
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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