BGC0001515 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001515 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	64,035

BGC0001515 - Region 1 - NRPS

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Location: 1 - 64,035 nt. (total: 64,035 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 64,036
Label		BGC0001515

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001515.1	0.89	NRP	aspercryptins	Aspergillus nidulans FGSC A4
BGC0001517.1	0.33	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0001261.1	0.33	NRP	AM-toxin	Alternaria alternata
BGC0001132.1	0.28	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001240.1	0.27	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001166.1	0.27	NRP	HC-toxin	Alternaria jesenskae
BGC0001135.1	0.26	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000334.1	0.26	NRP	cyclosporine	Tolypocladium inflatum NRRL8044
BGC0000357.1	0.26	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255
BGC0001825.1	0.25	NRP	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001515.1	1.00	NRP	aspercryptins	Aspergillus nidulans FGSC A4
BGC0001517.1	0.66	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0001261.1	0.66	NRP	AM-toxin	Alternaria alternata
BGC0001132.1	0.62	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001768.1	0.61	NRP	sansalvamide	[Nectria] haematococca mpVI 77-13-4
BGC0001240.1	0.60	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001166.1	0.60	NRP	HC-toxin	Alternaria jesenskae
BGC0001135.1	0.60	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000334.1	0.60	NRP	cyclosporine	Tolypocladium inflatum NRRL8044
BGC0000357.1	0.59	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 22091 - 64035:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-X - X - X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ANIA_07873

PKS_AT (1727..1929): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ANIA_07884

Search NORINE for peptide: strict or relaxed

AMP-binding (256..652): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A