LOCUS       BGC0001518             23499 bp    DNA     linear   CON 22-DEC-2016
DEFINITION  Aspergillus oryzae RIB40 DNA, chromosome 3.
ACCESSION   BGC0001518
VERSION     BGC0001518
KEYWORDS    .
SOURCE      Aspergillus oryzae RIB40
  ORGANISM  Aspergillus oryzae RIB40
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     This genome assembly has been updated so
            as to reflect the location and orientation of
            contigs on the chromosomes. Gap lengths were
            estimated using the results from Optical
            Mapping (http://www.bio.nite.go.jp/dogan/project/view/AO). This
            Aspergillus oryzae RIB40 genome consists of a nuclear genome
            assembly represented by eight chromosomes (assembled from 24
            entries) and three unplaced contigs (AP007156, AP007160 and
            AP007177) and a complete mitochondrial genome (AP007176).
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:44:00
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23499
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:4017]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..4017
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..23499
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..23499
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001518"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23499
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..4017)
                     /locus_tag="AO090026000585"
                     /old_locus_tag="AO070248000003"
     exon            complement(1..4017)
                     /locus_tag="AO090026000585"
                     /number=1
                     /old_locus_tag="AO070248000003"
     CDS             complement(1..4017)
                     /NRPS_PKS="Domain: AMP-binding (270-681). E-value: 1.2e-70.
                     Score: 230.1. Matches aSDomain:
                     nrpspksdomains_AO090026000585_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (831-889). E-value: 2.9e-12. Score:
                     38.5. Matches aSDomain:
                     nrpspksdomains_AO090026000585_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (949-1204). E-value:
                     7.7e-24. Score: 76.2. Matches aSDomain:
                     nrpspksdomains_AO090026000585_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     219.3; E-value: 1.2e-66)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AO090026000585"
                     /note="unnamed protein product; non-ribosomal peptide
                     synthetase modules and related proteins"
                     /old_locus_tag="AO070248000003"
                     /protein_id="BAE60013.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-77, bitscore:
                     250.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.9e-08, bitscore:
                     21.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.1e-22, bitscore:
                     69.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLEPWGPLYRKQDQDGSLDNIAVVSGDIPSPHPKNEPSQTSTLH
                     IPRDSDLDSDIPSVPTALIIAWGLTLSSLTGDEVVGFDLLPFRGDYQDLGARPYHFLLK
                     FGYREWSREAATTGMDLGSASSEGLPQGMGNRPQIAPSRFRNVLIIKQCSDAPGDSGSL
                     ESPSLGNVDKDEPTDAFRADMFISIQCGIGRTGIDVHCSFDPAFWTSENIRMILLDLSR
                     NFKEVMRCGRDDTPLTCLEGMSPKGLDCVLRRNIIPPPPKMEACVHHRFQARCRQNPSA
                     LAIDAWDGQLTYAELDSLSSQLASRLVSSITICPRGFMGVLMEKSAWVPVAILAVLKVG
                     SAFVFLDGSQPLQRLKIICAETKSQLVLSSAHYREKANTLGPPVLLVEKNQSGLGQAKE
                     NDSCPSLLEDYPQPQSQPQDTLYAVFTSGSTGEPKGAMVDHGAFCTMCGPQMAARPTTN
                     VSPRVFQFAPHAFTVSILDYLGTLLQGGCVCVPSEEELRNNMAGAIEGLSANIVTMTPS
                     MARVLDPTQTPSLQLVLLAGEMMAQCDLDKWSQCVRLLSLYGQSENAAGSMISEKSIVP
                     RAPNTFETLTPGFQCWIVSQDNPHRLMALGEVGELLLEGPALGQGYMNDPIQTEDKFIC
                     RSFCLEYAHSGSPQSYRLFKTGDLVRYTPAGEIELLGRKGAEVKLRGQRIDLTEIEHHL
                     RCLFPSATRVVADVIIPSDDIDGLHPVLAAFVQVDSVSRTGQSAEATFASPRPEFRAEA
                     KAVLSGLCQTIPSYMIPMTIIPTEAFPFTATGKLDRRSLRQYASAMSRSDLLKYVTDDR
                     GPVVTAVTPVEIIIHDACVEALGVSSDKVGMLDSFPDLGGDSLAARRMVSICRTKGLEL
                     AVADILAHSSLTSLAEKCSAGGGGAKQISQGVEMLDPFSTAKEEFLSHLPSFLPNADMI
                     ADVFPVQGAQRRAARAIDTFIFRLSGPVDADRLRDACQVLQQAHLALRSIFVPFYGKFM
                     QVVLRVPPLDFTRRLLPDGTDLVKWAESIGQADKTQRPPSEEFVVRFTLAETAGTPDYS
                     IFMMRLSHAQYDAGCLARIISDLWAVYEQKQLVVKSDFAQYARRAVQQTHLLSMEAFWR
                     DLLAGTTGLTPLPVTGISAEEERTIIVQQRVELKEPPPTGISMATVVRGAWSWVLHQQT
                     GNTVVVFNEMLNGRDVVPLEDTEPVVGACHSIVPVCVHFPLPQSGRTPRELLSALQEQH
                     LASLTFTTLDRDYLIQNCTEWTSHQSGFILAYQNFPEICDLVIGEDLSCQWASQVLDLA
                     EPGEAWVTATPLPGALQISLRVSTAAMDEQEANAWISALGQTIIRFLDSPDSVL"
     aSDomain        complement(406..1170)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AO090026000585_Condensation_DCL.
                     1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.70E-24"
                     /label="AO090026000585_Condensation_DCL.1"
                     /locus_tag="AO090026000585"
                     /protein_end="1204"
                     /protein_start="949"
                     /score="76.2"
                     /tool="antismash"
                     /translation="FIFRLSGPVDADRLRDACQVLQQAHLALRSIFVPFYGKFMQVVLR
                     VPPLDFTRRLLPDGTDLVKWAESIGQADKTQRPPSEEFVVRFTLAETAGTPDYSIFMMR
                     LSHAQYDAGCLARIISDLWAVYEQKQLVVKSDFAQYARRAVQQTHLLSMEAFWRDLLAG
                     TTGLTPLPVTGISAEEERTIIVQQRVELKEPPPTGISMATVVRGAWSWVLHQQTGNTVV
                     VFNEMLNGRDVVPLEDTEPVVGACHSIVPVCVH"
     CDS_motif       complement(1072..1170)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AO090026000585_0004"
                     /evalue="1.10E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="AO090026000585"
                     /protein_end="982"
                     /protein_start="949"
                     /score="27.3"
                     /tool="antismash"
                     /translation="FIFRLSGPVDADRLRDACQVLQQAHLALRSIFV"
     aSDomain        complement(1351..1524)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AO090026000585_PCP.1"
                     /evalue="2.90E-12"
                     /label="AO090026000585_PCP.1"
                     /locus_tag="AO090026000585"
                     /protein_end="889"
                     /protein_start="831"
                     /score="38.5"
                     /tool="antismash"
                     /translation="EALGVSSDKVGMLDSFPDLGGDSLAARRMVSICRTKGLELAVADI
                     LAHSSLTSLAEKC"
     aSModule        complement(1351..3207)
                     /complete
                     /domains="nrpspksdomains_AO090026000585_AMP-binding.1"
                     /domains="nrpspksdomains_AO090026000585_PCP.1"
                     /locus_tags="AO090026000585"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1945..2007)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AO090026000585_0003"
                     /evalue="5.20E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="AO090026000585"
                     /protein_end="691"
                     /protein_start="670"
                     /score="22.1"
                     /tool="antismash"
                     /translation="LGRKGAEVKLRGQRIDLTEIE"
     aSDomain        complement(1975..3207)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AO090026000585_AMP-binding.1"
                     /evalue="1.20E-70"
                     /label="AO090026000585_AMP-binding.1"
                     /locus_tag="AO090026000585"
                     /protein_end="681"
                     /protein_start="270"
                     /score="230.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FQARCRQNPSALAIDAWDGQLTYAELDSLSSQLASRLVSSITICP
                     RGFMGVLMEKSAWVPVAILAVLKVGSAFVFLDGSQPLQRLKIICAETKSQLVLSSAHYR
                     EKANTLGPPVLLVEKNQSGLGQAKENDSCPSLLEDYPQPQSQPQDTLYAVFTSGSTGEP
                     KGAMVDHGAFCTMCGPQMAARPTTNVSPRVFQFAPHAFTVSILDYLGTLLQGGCVCVPS
                     EEELRNNMAGAIEGLSANIVTMTPSMARVLDPTQTPSLQLVLLAGEMMAQCDLDKWSQC
                     VRLLSLYGQSENAAGSMISEKSIVPRAPNTFETLTPGFQCWIVSQDNPHRLMALGEVGE
                     LLLEGPALGQGYMNDPIQTEDKFICRSFCLEYAHSGSPQSYRLFKTGDLVRYTPAGEIE
                     LLGRKGAEVKLR"
     CDS_motif       complement(2119..2205)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AO090026000585_0002"
                     /evalue="9.80E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="AO090026000585"
                     /protein_end="633"
                     /protein_start="604"
                     /score="30.7"
                     /tool="antismash"
                     /translation="LGEVGELLLEGPALGQGYMNDPIQTEDKF"
     CDS_motif       complement(2698..2754)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AO090026000585_0001"
                     /evalue="4.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="AO090026000585"
                     /protein_end="440"
                     /protein_start="421"
                     /score="25.4"
                     /tool="antismash"
                     /translation="YAVFTSGSTGEPKGAMVDH"
     gene            complement(4989..6527)
                     /locus_tag="AO090026000584"
                     /old_locus_tag="AO070248000004"
     exon            complement(4989..6527)
                     /locus_tag="AO090026000584"
                     /number=1
                     /old_locus_tag="AO070248000004"
     CDS             complement(4989..6527)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 172; E-value: 3.6e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090026000584"
                     /note="unnamed protein product; cytochrome P450 CYP2
                     subfamily"
                     /old_locus_tag="AO070248000004"
                     /protein_id="BAE60012.1"
                     /sec_met_domain="p450 (E-value: 3.2e-66, bitscore: 213.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLILAFAVILLSTCWFLWYSRKAVFDRLPPGPRPLPFLKSRQEL
                     RQTRQWEALDDLHRQYGPLVGMTWGGRPAVLIGKREIAKDLFGKRGSIYSSRARLVMGL
                     DIMTGGDHVFFLPYGPKWKKLSRIQATFLNRPAVKHYRPLQELESLHTLQDLLHSDDYE
                     ACFSRFQASLTHALAYGTRLHSATDPQLTELENIARTFISAATNSHWMVDSFPILKYVP
                     ACLAPWKRFGQQIHAQTVSLFQGKMAVAEHTRSWNWVKHIRALKHTSGVTDHEMVYVIG
                     SIYQAGVGIITATLRLFIMACVLHPEAVKAAQDELDRVVGSDRLPTLNDLGHLPYVEAF
                     VKEVLRWRPLVLAATHSVTQDDDYRGYRIPRHAVILSNQWAMDMDREVWDSPEQFRPDR
                     WMSDRKRMPSAFGLGQRMCAGQYMAMESLLIMASRMLWAFTFEHAWEGGKRVEIDSWAF
                     HEESLFLVPKPYRARIQPRDPHRLHVIQSTWQAAEKDIDPLLDQIGREIHTASA"
     exon            complement(7901..7950)
                     /locus_tag="AO090026000582"
                     /number=3
                     /old_locus_tag="AO070248000006"
     gene            complement(order(7901..7950,8082..8182,8252..8976))
                     /locus_tag="AO090026000582"
                     /old_locus_tag="AO070248000006"
     CDS             complement(join(7901..7950,8082..8182,8252..8976))
                     /codon_start=1
                     /locus_tag="AO090026000582"
                     /note="unnamed protein product; predicted protein"
                     /old_locus_tag="AO070248000006"
                     /protein_id="BAE60011.1"
                     /transl_table=11
                     /translation="MTKINPYKGILVELKDIVFTSSSDQIKLPINTFKSILCCGATAQY
                     QCGKINRAQYYSRLARDFALSLADVTALFDTVQATIRPEESFLAFLAELKSRFGEQLKL
                     YAVANMSREDYAMLKSLPIDWSLFDGVFLSADLGMRKPELRFFRHVLESISMKPEDTIL
                     VDNDTDNILCALSMGLKGILFGSTSVPQALTNLLEYDHISRAEQFLRSHAKSLHSVTHT
                     GVTIRENFAQLLILEATGDIDLVELEYHPTTWNYFIGTQSSQLLLHKHNADRMTTMTSC
                     WLVSAFLVVS"
     exon            complement(8082..8182)
                     /locus_tag="AO090026000582"
                     /number=2
                     /old_locus_tag="AO070248000006"
     exon            complement(8252..8976)
                     /locus_tag="AO090026000582"
                     /number=1
                     /old_locus_tag="AO070248000006"
     exon            9938..10021
                     /locus_tag="AO090026000581"
                     /number=4
                     /old_locus_tag="AO070248000007"
     gene            order(9938..10021,10084..11190,11250..11416,11472..11652)
                     /locus_tag="AO090026000581"
                     /old_locus_tag="AO070248000007"
     CDS             join(9938..10021,10084..11190,11250..11416,11472..11652)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 347.7; E-value:
                     1.7e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090026000581"
                     /note="unnamed protein product; cytochrome P450
                     CYP3/CYP5/CYP6/CYP9 subfamilies"
                     /old_locus_tag="AO070248000007"
                     /protein_id="BAE60010.1"
                     /sec_met_domain="p450 (E-value: 3.2e-76, bitscore: 246.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEALPTYLESFWHSGGGTMGISILVMLSTFLALGTIFVYRIWLHP
                     LSGFPGPKCCSVSSIPVAWAQLRGRNHEFVSSLHRKYGSVVRISPSELSFISGAAWNDI
                     YSRSKGRPALERDRTFFNDMLVDPETITMANEATHSRIRRAMAPAFSPRALLEQEPIIQ
                     ANIKLLMDKLEARAGSGGAPTDLRAWFNYTTFDLIGDLAFGESFGCLATSTCHEWVQFV
                     LDHFYTSTLLHVVHRFHPFNRVLAALLPKSLIEKRKAHDSMTLTKVHRRLEVQGRRNDF
                     TQHLLDAAEAGTLSSREVEKQASVLILAGSETTSVALTFAIYLVLTNKPVLDQLNDELH
                     STFKEEQEINLLSVNQLKYLHAVIQEALRFCPPISNGFPRQTPPQGATVDGMFIPGKTV
                     VNINHWAAYRSPRNFTLPEQFLPERWLGDPRFDEDAKDVFQPFSVGPRNCIGKKFAYDS
                     MKLILAKFLWRFKPTLLDKSRSWLAHQPTFVSFHQPPLLVDLEIKGSDAFPVRE"
     exon            10084..11190
                     /locus_tag="AO090026000581"
                     /number=3
                     /old_locus_tag="AO070248000007"
     exon            11250..11416
                     /locus_tag="AO090026000581"
                     /number=2
                     /old_locus_tag="AO070248000007"
     exon            11472..11652
                     /locus_tag="AO090026000581"
                     /number=1
                     /old_locus_tag="AO070248000007"
     gene            12716..13501
                     /locus_tag="AO090026000580"
                     /old_locus_tag="AO070248000008"
     exon            12716..13501
                     /locus_tag="AO090026000580"
                     /number=1
                     /old_locus_tag="AO070248000008"
     CDS             12716..13501
                     /NRPS_PKS="Domain: PKS_KR (13-178). E-value: 7.5e-09.
                     Score: 27.6. Matches aSDomain:
                     nrpspksdomains_AO090026000580_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     220.1; E-value: 5.6e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090026000580"
                     /note="unnamed protein product; dehydrogenases with
                     different specificities (related to short-chain alcohol
                     dehydrogenases)"
                     /old_locus_tag="AO070248000008"
                     /protein_id="BAE60009.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-33, bitscore:
                     105.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGNEQKFSLQGKVAIVTGAGSGIGRETALCLANAGANVVVAEAN
                     ETTGKETAAKVSAQTGSRGLFILTDVSRSESVQAMVIATIEAFGRLDIAVNNAALHPDA
                     SPIAELHEDHWQKIIGVNLVGVAFCLKWELQQMIQQGGGGSIINISSATINRPQEKMSA
                     YIAAKHGITGLTQTAAVENGRHGIRVNALAPGGVATDLTMATMQELGLTEENEAARSSL
                     FKRFAKPEEIAQSVLWLASDAASYVTGATIAVDSGLSLI"
     aSDomain        12755..13249
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AO090026000580_PKS_KR.1"
                     /evalue="7.50E-09"
                     /label="AO090026000580_PKS_KR.1"
                     /locus_tag="AO090026000580"
                     /protein_end="178"
                     /protein_start="13"
                     /score="27.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIVTGAGSGIGRETALCLANAGANVVVAEANETTGKETAAKVSA
                     QTGSRGLFILTDVSRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQK
                     IIGVNLVGVAFCLKWELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQ
                     TA"
     CDS_motif       12761..12829
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AO090026000580_0001"
                     /evalue="4.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="AO090026000580"
                     /protein_end="38"
                     /protein_start="15"
                     /score="13.0"
                     /tool="antismash"
                     /translation="IVTGAGSGIGRETALCLANAGAN"
     gene            complement(13922..15487)
                     /locus_tag="AO090026000579"
                     /old_locus_tag="AO070248000009"
     exon            complement(13922..15487)
                     /locus_tag="AO090026000579"
                     /number=1
                     /old_locus_tag="AO070248000009"
     CDS             complement(13922..15487)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 199.1; E-value: 2.1e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090026000579"
                     /note="unnamed protein product; cytochrome P450 CYP2
                     subfamily"
                     /old_locus_tag="AO070248000009"
                     /protein_id="BAE60008.1"
                     /sec_met_domain="p450 (E-value: 4.4e-72, bitscore: 232.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPTLPNIAGRINTMATFLLPVAIGTIILLFLYGKYVTSTLIPGP
                     PTLPLIGNLHQLPSDDRRHVLAQWHKKHGPIISLKFGWSSVVILGNIAVTKELFGKRSL
                     KYGSRPRMVMARDCMTKQMQTSTLPWGEKWKIHNRIQLSLVGGPKIRSYQSLLDIESCK
                     VLYQLLSTESLVTCFNRFKFNIIYTLAYGKDPDQNESDFHEILELADHFTQTLTNATWV
                     VDLFPILNCLPRRLAPWKAVGDDFHRRAMGWFRRNSEAAVKSNSWNWTKHVQFNEDTGN
                     LSVSEMQYLIGVLFEAGVDSTATVLHFFVLACTLYPDAVTKARQELDKVVGSARLPTPK
                     DLPQLPYVKAFIQEVLRWRPITAEGLPHFTLEDDKYQGYDIPKGSTVIFNYWSGHMDED
                     TYQHADQFCPERWIERPDLPLGVFGYGRRACAGRRLALMSLETLIPKLLWAFDFRSPAG
                     TDHGKSRDPGTEHQGALIKPRSFPVSWHPVSNDRRLIIERLFQERDKDLDTVLDDIGKA
                     FERY"
     exon            16076..17464
                     /locus_tag="AO090026000578"
                     /number=2
                     /old_locus_tag="AO070248000010"
     gene            order(16076..17464,17555..17581)
                     /locus_tag="AO090026000578"
                     /old_locus_tag="AO070248000010"
     CDS             join(16076..17464,17555..17581)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090026000578"
                     /note="unnamed protein product; predicted protein"
                     /old_locus_tag="AO070248000010"
                     /protein_id="BAE60007.1"
                     /sec_met_domain="Transferase (E-value: 4.2e-27, bitscore:
                     84.2, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEQTEFEPIQLSPLDQAIPPVYIRILLCFSVVNVDRAISQLQTG
                     VSSLLSALPFLSGDVVRYTAPGKTKWLYQLCPPTHQVQATGVLVVKHHQMRCMVDEKRF
                     APSSTSHIPLSPFAEPARPAPIFRVQANAYIDGITLGFAFHHIAVDATGMGVIISELAR
                     HCRSSPPPSLLCPDYERATRQLISNSRATECSGLDHSGDYISCQALSPPAEGSEDASPS
                     IEISTETRTFVFPAARLESLKNACIEMLPTLDQQQRQQNPCLDEPARTKVPWLSTNDVF
                     VALLWVCLTRCRYQEDQNSGLPSDEHTRICMGVNMRSRIQPPLSADYLGNAILSLSFKL
                     NVNVFRRTQVTNESIEGVDSKDIEHKQWLATICRVARNIRRGVNGMDDSYFRSVVSFLE
                     DSSDCRLFDYARCDFCVPSWRHLCVYHADFGEMGRPKSLEVFDVPGDGSFCILPQHYGA
                     AAPWELLLGLLKA"
     exon            17555..17581
                     /locus_tag="AO090026000578"
                     /number=1
                     /old_locus_tag="AO070248000010"
     exon            18194..18448
                     /locus_tag="AO090026000577"
                     /number=3
                     /old_locus_tag="AO070248000011"
     gene            order(18194..18448,18519..19325,19379..20011)
                     /locus_tag="AO090026000577"
                     /old_locus_tag="AO070248000011"
     CDS             join(18194..18448,18519..19325,19379..20011)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 378.2; E-value:
                     7e-115)"
                     /gene_kind="transport"
                     /locus_tag="AO090026000577"
                     /note="unnamed protein product; predicted transporter
                     (major facilitator superfamily)"
                     /old_locus_tag="AO070248000011"
                     /protein_id="BAE60006.1"
                     /transl_table=11
                     /translation="MTDISTGVQLKPGIGDGTVYNGNMSKDTLVNCSPDPENPEKGQAS
                     SPRTQISVDDNEESTTEYPSSWKLAMIMISLCLAVFCLALDTTIMATAIPKIADQFNSL
                     NDVGWYGSAYLLTTSALTLSFGKLYSFYSIKWVYLQALGMFEIGSLICGATPNSLGLII
                     GRAIAGSGSAGIYSGSMLIVARSAPLERRPLLTGILGGLFGVASVVGPLIGGAFTDNLS
                     WRWCFYINLPLGAVTGLFLILFFDGAKATTQRATIRDQLSQLDLLGSLCFLPAIICVLL
                     ALQWGGTTYPWHDGRIIALFTVFGVLLLAFAGVQWWRQEKATVPPRLIANRNVWGAALF
                     SFCLNASFIIFTYYLPMWFQSIKGVTATQSGIMNLPMVLAVVIFSIISGGLVGALGYYT
                     PFMVIAPLIAAIGAGLLSTLRMDSNNASWIGYQILYGVGVGCGLQQPIVAVQGSLAPAD
                     LPTGTVIVMFMQTIGGAIFMSVGQNVFQNQLMRNLATQAPSVDAARVLQAGATMLRKTV
                     SSDLLPAALRAYNSAITEAFYVAVAMAVLALPGALVMQWISVKGRQL"
     exon            18519..19325
                     /locus_tag="AO090026000577"
                     /number=2
                     /old_locus_tag="AO070248000011"
     exon            19379..20011
                     /locus_tag="AO090026000577"
                     /number=1
                     /old_locus_tag="AO070248000011"
     gene            20512..21117
                     /locus_tag="AO090026000576"
                     /old_locus_tag="AO070248000012"
     exon            20512..21117
                     /locus_tag="AO090026000576"
                     /number=1
                     /old_locus_tag="AO070248000012"
     CDS             20512..21117
                     /codon_start=1
                     /locus_tag="AO090026000576"
                     /note="unnamed protein product; predicted protein"
                     /old_locus_tag="AO070248000012"
                     /protein_id="BAE60005.1"
                     /transl_table=11
                     /translation="MTRQSHYQAIILDLGNVVFEWDTSQNPPTAAPNQISLLRTSMKSP
                     VYHSYERGQLSTEECHRLLGESLHVDPGQIKEAFDLARQSLRSNPALLDFIRQLKQTRG
                     VAVYAMSNIPQAEIEYLKESRAGDMEVFDEVFASGYVGSRKPETEFYRRVMGEIGLKAE
                     RVVFVDDKEENVDVARGLGLYGVCFGGVEELRGHLLGI"
     exon            complement(21178..21349)
                     /locus_tag="AO090026000575"
                     /number=4
                     /old_locus_tag="AO070248000013"
     gene            complement(order(21178..21349,21406..21581,21653..22762,
                     23455..23499))
                     /locus_tag="AO090026000575"
                     /old_locus_tag="AO070248000013"
     CDS             complement(join(21178..21349,21406..21581,21653..22762,
                     23455..23499))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 357.2; E-value:
                     2.3e-108)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090026000575"
                     /note="unnamed protein product; cytochrome P450
                     CYP3/CYP5/CYP6/CYP9 subfamilies"
                     /old_locus_tag="AO070248000013"
                     /protein_id="BAE60004.1"
                     /sec_met_domain="p450 (E-value: 1.9e-70, bitscore: 227.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRFPIQVAQSEIPPIAWGLWRMVYRLWLHPLSGYPGPRLAAVS
                     NLPYFAWTCTGNLHLRLQELHKVYGDVIRIRPNALTYRTPEAWTDIYGHRKPGTLPFSK
                     DPEFFMPAQAGSSHMINANEKDHTRQKRLLNHAFSERSLRQQEHLIMGYIDLFIQRLRG
                     QARMGAETVNMEEWLNFLTFDIIGDLAFGEPFGCLQNSEYHPWVATIFKSIKTGAILRA
                     LNIYPILLGFIRRFLPKSLVQKRIAHYQMSKDRVTRRLQTETSRPDFISYILKYNDDRG
                     MSTPEIEMNAALLIQAGSETTATVLAACLYFLQKNAACHRRLVQDIRSAFTQETDINFL
                     SAAQLPYMNGVIEESLRLFPPAPGIGPRVVPKGGARICGRYVPGGVSVSVGHYSTFRSA
                     RNFTRPNEFLPQRWLDRDAESEFASDQTMALQPFSYGPRACIGRNLAYAEMRTILAKIL
                     WHFDVQLDERSADWANSKSYIVWEKGPLWLKLHPRNVPQETD"
     exon            complement(21406..21581)
                     /locus_tag="AO090026000575"
                     /number=3
                     /old_locus_tag="AO070248000013"
     exon            complement(21653..22762)
                     /locus_tag="AO090026000575"
                     /number=2
                     /old_locus_tag="AO070248000013"
     exon            complement(23455..23499)
                     /locus_tag="AO090026000575"
                     /number=1
                     /old_locus_tag="AO070248000013"
ORIGIN
        1 ttataaaaca ctatcaggag aatcaagaaa ccgaatgata gtttgaccca gcgctgaaat
       61 ccatgcattg gcctcttgct cgtccattgc tgcagtggac acgcgtagac tgatctgcaa
      121 agcccctggc agaggcgttg ctgtcaccca agcctcaccg ggctcagcaa gatcaagcac
      181 ctgagacgcc cactgacaag acagatcttc cccgatcact aggtcgcaga tctcagggaa
      241 gttctgatag gccaggataa accctgactg gtgactagtc cattccgtac agttctggat
      301 gaggtagtct ctgtccagag tggtgaaggt gagcgacgcc aagtgctgtt cctgcagagc
      361 cgacaggagt tccctgggag tccgacccga ttggggaagg ggaaaatgaa cacagacagg
      421 aacaatggag tgacaggccc cgacgacagg ttcggtgtcc tccagtggca ctacatcgcg
      481 accgttgagc atctcgttga acactacgac cgtgttcccg gtctgctggt gtagcaccca
      541 tgaccaagcc cctctgacga ctgtagccat cgagatgcca gtggggggtg gttcttttaa
      601 ttctacacgt tgttgaacaa tgatggttct ctcttcctcc gccgagattc ctgtaaccgg
      661 cagcggtgtc aaaccagtgg taccggcaag caggtcgcgc cagaatgcct ccatgctcag
      721 aagatgagtt tgctgtactg ccctacgggc gtattgggcg aagtcagact tgacaacgag
      781 ttgcttttgc tcgtatacgg cccacaagtc agaaatgatg cgggccagac accctgcgtc
      841 gtactgggca tgcgatagcc gcatcataaa gatactgtag tctggagttc cggcggtctc
      901 tgctagagta aaccgcacta cgaactcttc tgacggaggt cgctgagtct tgtccgcttg
      961 gccaatcgac tcagcccatt tgaccagatc agttccgtcc ggcagaagtc ggcgagtgaa
     1021 gtcgaggggt ggtactcgca acacgacttg catgaacttc ccatagaacg gcacaaagat
     1081 ggatcgaagg gccagatgtg cctgttggag gacctggcac gcatctcgta gccggtcagc
     1141 atctactggg ccagacagac gaaagataaa cgtgtcaatt gctctggctg cccggcgttg
     1201 tgccccctgc acaggaaaga cgtctgcgat catgtccgcg ttcggcagga agctgggaag
     1261 atgagacaaa aattcttctt tggctgtgga gaaaggatcc aacatctcga ctccttgaga
     1321 gatctgtttt gccccgccgc ctcccgcaga gcacttctct gccagtgagg tcaaagaaga
     1381 atgggccagg atatccgcca ctgccagctc caaccccttc gtacggcata ttgaaaccat
     1441 gcggcgggca gctagagaat ctccgccaag gtctgggaaa ctatccagca tgccaacttt
     1501 gtcggaagag acacccaacg cctccacaca cgcatcgtga ataatgatct ctactggagt
     1561 cacagcagtt accacaggcc ctctatcatc ggtgacatat ttgagtaagt cactacggga
     1621 catggcagag gcatactggc gaagagaccg ccggtctagc ttgcctgtgg ccgtgaacgg
     1681 aaatgcctcg gttggaatga ttgtcatggg aatcatgtaa ctaggaatgg tctggcaaag
     1741 acccgaaagt acggcctttg cttccgcacg gaactcgggc cttggagaag caaaagtcgc
     1801 ttccgcggac tggccagtac ggctcactga gtcaacctgg acgaatgcag ccaacaccgg
     1861 atgaaggccg tcgatatcgt ccgagggtat aatgacgtcg gccaccaccc gagtcgcaga
     1921 tgggaagagg caccgcaggt ggtgctctat ttcagtgagg tcaatgcgtt ggcctctgag
     1981 cttgacctca gcccctttgc gccccaggag ctctatctca cccgccggcg tgtagcgcac
     2041 aagatcacca gtcttgaaaa gccggtagct ttgaggactg cctgagtgag catattcgag
     2101 acagaacgag cgacagatga atttgtcctc cgtctggatc ggatcgttca tgtaaccttg
     2161 ccccagggcc ggcccttcga gcaacagctc cccgacttca ccaagagcca tcagccggtg
     2221 aggattatct tgagacacaa tccagcattg gaagccgggg gttaatgtct cgaatgtatt
     2281 tggagcacgt ggaacgatgg acttttccga aatcatcgag ccagcagcat tctcagactg
     2341 cccatataag gacaagagcc ggacacactg gctccactta tccaggtcac actgggccat
     2401 catttctcct gccaatagca ccagttgcag agaaggtgtc tgtgtaggat ccaagacccg
     2461 tgccatcgat ggagtcattg tcacgatatt ggcactgagg ccctcaatag caccggccat
     2521 gttgttccgc aattcctctt cagagggtac gcatacacag cctccttgaa gcaaggttcc
     2581 tagatagtcc aagatgctaa ccgtgaatgc atgaggggca aattggaata cccggggtga
     2641 cacattggtc gtaggacggg cagccatctg cggaccacac atggtgcaga acgccccatg
     2701 gtccaccatt gctcccttgg gctccccggt tgagccggag gtgaaaacag catacagcgt
     2761 gtcttgcggt tgcgactgcg gttgcggata gtcttccagg agtgatggac aactatcgtt
     2821 ctctttagct tgacctagac ctgactggtt cttctccact agtaaaacgg gtggccccaa
     2881 cgtgttcgct ttctctctgt aatgagctga tgatagaacg agctgggatt ttgtttcggc
     2941 acaaataatc ttgaggcgct ggagaggctg tgaaccatcc aagaaaacaa acgcgctgcc
     3001 caccttcaga acggctagga tagctacggg gacccaggcc gacttctcca tcagcacacc
     3061 catgaatcca cgggggcaaa tggttatgga ggatacgagc cgggatgcca gttgggagga
     3121 aagagaatcg agctcggcat acgtcaattg accgtcccac gcatcgatgg ccaacgctga
     3181 tggattctgc cggcatcgag cctggaatct gtggtgcaca catgcttcca ttttgggtgg
     3241 aggtgggatg atattcctcc ttagcacaca atctaggccc ttgggactca ttccctccag
     3301 gcaagttaga ggagtgtcgt cacgaccaca tcgcatgact tctttgaagt tccgagatag
     3361 atccaacagt atcatgcgga tgttctcgct ggtccaaaag gccggatcaa atgagcaatg
     3421 cacatcaata ccagtcctac cgataccaca ttgtatggaa atgaacatgt ctgctcgaaa
     3481 ggcatctgtg ggttcgtctt tatcaacgtt ccccaaagaa gggctttcta gggaaccact
     3541 gtccccagga gcgtcggaac attgtttgat gatcaagaca tttcggaatc gactaggggc
     3601 tatttggggt cgattgccca tgccttgggg aagcccttcc gaagaggcac tccccagatc
     3661 catcccagtc gtcgcagctt ctctggacca ttcgcggtag ccaaacttga gaagaaagtg
     3721 atatggtctt gcacccaagt cctgatagtc tccccggaat ggtagcaagt cgaagccaac
     3781 cacctcatct ccggtaaggc tggacagggt gaggccccat gcaatgatca gggctgtagg
     3841 taccgacggg atgtcactgt cgagatcaga atcccgggga atatgaagag tggaagtctg
     3901 tgatggttca ttctttgggt gaggtgaggg aatgtctccg gatacaactg cgatattatc
     3961 cagactccca tcttggtctt gtttgcgata aagcggtccc cacggctcca ggtccatagt
     4021 ggcggtaatt tcctctttcc taggcgtgtt atctgcgaaa ggatactgaa gatgaggcca
     4081 gacaatgcgc ctgtctcttt gaaaatgaac agtgatgtca aatattcgtt cctcaggcaa
     4141 gactagagta tcgcgagagt atcatccaca acatttacca cgttgggggt atcaacaggc
     4201 tccaatttgg gagtataatc tcccctcaca gggggggggg aatcaatctc actagcaacc
     4261 aggcatattt ccacatcact gaatctggtc ggtcaagaac gtctgccagc tagccacatg
     4321 ggtagacatg caggtaaccc ttgccaaatg tgatgaggtg ccattcttgg gggtgcgtta
     4381 cttagctcac tgcatacatt ctccatgact tgtctcattg ggatccctca cataccttct
     4441 gctatacgac atccgttaca gcggccagaa tatctgctta gtctgaaatc gtacatcctt
     4501 ccccttgtgg aaaaatacca agctcaaata atgctattat attgaaatag aactcataga
     4561 gataacatgt ttttaacttt ttcgtaaggt ttgtagaatt ggtatttaaa acaatgaaac
     4621 tgtaatacgt ttacgagtat gctgtatctt attctctttt cggcaatact cgaagatatc
     4681 tcaacttatt gaaaactcgt cgctgcaaga cgataaactt tggaaacccg aagatcaccc
     4741 gcacttattc agaataactt tgaaaaatta cttttcttct atgtatagct taattgctga
     4801 cagttgtcag gaagtaaact ctaagtaaac ggacctattc aaggtccact tgcataggtc
     4861 tagactctag agctgcaagg tgcaagccaa tgaataacag ctgcaagcta atacgagatg
     4921 cattgcagat tgcttctgga ctacaagaag tgacgaaaac aggagtttct ctcatttgcc
     4981 acatgcgttt atgcggaggc cgtgtggatt tctcgtccga tctgatcgag cagaggatcg
     5041 atgtcctttt cagcggcctg ccaggtcgac tggatgacat gcaaccgatg cggatctcgg
     5101 ggctggattc tcgcccgata cggcttcggc accaggaaaa gactctcctc atggaaggcc
     5161 caggagtcga tctcgactcg cttgcccccc tcccatgcat gttcaaaagt gaacgcccag
     5221 agcatcctcg acgccatgat caacaaggac tccatcgcca tgtactggcc ggcgcacatg
     5281 cgctgcccca atccaaaagc gctgggcatt ctcttcctgt cggacatcca tcggtctggt
     5341 cggaattgct cgggcgagtc ccacacctcc cgatccatat ccatcgccca ctggttggac
     5401 agaatgaccg cgtgacgggg aattcgatag ccccgatagt cgtcgtcctg cgtcaccgag
     5461 tgcgtcgcgg ccaggacgag tgggcgccac cgaagcacct ctttcacaaa tgcttcgacg
     5521 taagggagat ggcccagatc attcagagtc gggagtcgat cgctgccaac cacccgatcc
     5581 agctcgtcct gggcagcctt gaccgcttcg gggtgcaaga cacaggccat gatgaagagc
     5641 cggagggtgg cggtgatgat ccccacgcca gcctggtaga tgctcccgat cacgtagacc
     5701 atttcatgat ctgtcactcc actggtgtgc ttgagcgcgc ggatgtgctt gacccagttc
     5761 cacgaccggg tgtgttcggc gacggccatc ttcccttgga aaaggctgac ggtctgcgca
     5821 tgaatctgct gaccgaatcg cttccagggc gccaagcaag ccggaacata cttgaggatc
     5881 gggaacgaat ccaccatcca gtggctgttc gttgcggcgg agatgaaagt ccgggcgata
     5941 ttctccagtt ccgtcagttg tgggtcggtg gcactgtgta accgcgtccc ataggcaagg
     6001 gcatgggtca ggctggcctg gaagcgcgaa aagcaggcct cgtaatcatc gctgtgcagc
     6061 aggtcctgga gggtgtgcaa gctttccagc tcctgcagag gacggtagtg tttgacggca
     6121 gggcgattga ggaacgtggc ttggatccgg ctcagcttct tccacttggg tccgtatgga
     6181 agaaaaaaca catggtcccc gccggtcata atgtccagcc ccattacaag gcgagcccgg
     6241 gagctgtaga tactgccgcg ctttccgaag aggtctttgg caatctcgcg tttcccgatc
     6301 aagactgctg gccgtccccc ccaggtcatt cccaccagag gtccgtattg acggtggagg
     6361 tcgtctaaag cctcccattg tcgagtttga cgaagctcct ggcgactttt aagaaacggc
     6421 aatggtctcg gccctggagg cagacgatca aacactgcct ttcgagaata ccagaggaac
     6481 cagcatgtcg acagaaggat gacggcaaat gctaatatta gacccatcat tgcggactaa
     6541 ttggaatagt aacggtaata gttgctggat gatgcaaaac acggtagatt ggctggaata
     6601 attacagaga ctttatattg agaccaaacc ggtacatatt cacaaagtat aagctaccta
     6661 aaacgagaaa aaaaaaaaaa aaaaaaaaaa agaaataaaa gaaaaactaa aaactaaaac
     6721 agcaacagag tcataagcta gttcgacctc cgcaaagcaa ggagactgtt cgacattact
     6781 tatgagatca gtggagagaa ggcggcatgg ctgtcccagt attgcatacg actatctcgc
     6841 ccaggatgat caattgcaag gagcccagat gggtaaacct tgagaaagaa gttatgttac
     6901 gtctggtatt cgaaagcttg tgatatgtct ctaggagaat gcctcttaca cataatttcc
     6961 attttcgtag gaagctgaga aatattttga gctgcatatc tggatgcatt aatctaatag
     7021 tacgattgac tagaatgata tcatgctgtt acctttgtac taatcctcca atcttcatat
     7081 cccagtgcga attagaccat gctcctctgc attctgcatc tgggacgttg agactagtgc
     7141 tactggatag atagatagaa agattgtatt gaattgaata gatcccgaga acaaactcgt
     7201 ctaccccaag acttcataaa tccaagaggc tgttgagatc cgaaccccaa cgatatccta
     7261 aacagtctgc agtaagagca agtaatcgat gtgtgccaag agttaagctt cgtaagagtt
     7321 gtagacatcc gaatgatttg gcaggtcaaa ttccagcgca ctggttggct tgacattgct
     7381 tgattgcttt gatggccatt gccgtggata ctccctggtt tccgatcggc agccttttag
     7441 atgcgtaatg gtacatcgtt cctagatccc agctgccatc tggattttgc atggacaaca
     7501 atgcgttgag tcccatgcgg tcatggatcc caaccccatt gcaagcgatc aggcgcatgg
     7561 acaagctgat cgggtctact ggtacaccaa cacgctcctg aaggcgctcc ttaagtagta
     7621 ccttgagccc atcatatagc tggggtagat gggttatatg ctgcaggaag cgaaagaaga
     7681 aatacagaaa ggcttcaggc ataggataga atgcagtccc attgatgtat gctcgtcgaa
     7741 tgagcacttg acgtacccag gccaaagtgt gatgcaactc atggccacga ccgtatttgt
     7801 agaacaggct cagcacattg cagcatacaa ctggatccac acggttttta aaatctgtga
     7861 agaatgtctg gactcaactt agtcagcctg cttgttgcag ctaagagact accaggaagg
     7921 cggatactaa ccagcatgag gtcatcgtcg cttcgatatt tgagcatctc gtccataatt
     7981 tcatttgcta tatctttggg tcgatcgagc acggtcgtgg caagcgatgt tgtgtccaga
     8041 tcatgcggaa actctgtctg tgtgagtacg ggtgtaccta ctcattcgat cagcattgtg
     8101 cttatgtagc agcagttggg agctttgggt accaatgaag tagttccatg tagttgggtg
     8161 gtattcaagc tcgacaagat cgctttcaag accagtcagt gttggaaagg aggttgcaag
     8221 ttggagattg atatgggata tagacaccta catgtcaccc gtggcctcta ggatgagtaa
     8281 ctgggcaaaa ttctccctga tggtgactcc tgtgtgggta actgaatgta gggacttcgc
     8341 atggctacga aggaattgtt ccgcacggga gatatggtcg tattcgagga gattggtcaa
     8401 ggcttgtgga acagaagttg atccaaaaag aattcctttg aggcccattg acagcgcaca
     8461 cagaatattg tccgtgtcgt tatcaaccag gattgtatct tcgggcttca tcgatatgct
     8521 ctccaggaca tggcggaaga agcgcaattc tggctttcgc attccaagat ccgcggagag
     8581 aaacactcca tcgaacagag accagtctat gggaagtgac ttgagcatgg catagtcctc
     8641 ccgggacata ttggccacag catacaactt caactgctcc ccgaaccgac tcttcagctc
     8701 agccaggaag gccaagaatg attcctcggg gcggatggtc gcctggaccg tatcaaatag
     8761 ggcggtaaca tctgccaacg agagcgcaaa atccctagca agacgggagt aatattgagc
     8821 tcgattgatt tttccacatt gatattgagc cgttgcacca cagcacagaa tagatttgaa
     8881 ggtgttgata gggagcttga tctggtccga ggaagaagta aaaacgatgt ctttcagctc
     8941 aaccagtatc cccttgtagg ggttgatctt ggtcattatt gacgttgcct gaaacgagtg
     9001 gtctaatgtt gacttctatt gagggttctt gtagcctggg ccttagttaa tcaggggatt
     9061 aaatacccta ggctttggcg agtcgctaaa tgatttgcag ccaactgata agggccagat
     9121 ctgatgtaca cttcagtctc gctgaatcga tccaatcatt tgattggcaa gagttctcta
     9181 ggtgattcta atgcatatca tctagggatg acccaaagcc ttttaccaaa gtcgtgaaca
     9241 tgcccccgcc agaaaaccta cctcaagccc gccctgctca aaattccaaa ttctatcgaa
     9301 atgttttaat agatttgtat gactaaaact ctcaatattg gattgacagc atcataagtg
     9361 ggtcatattg gcggaattac ttgccgtatg cacggagaaa ctcgggcagg gaatctttgt
     9421 tgctacgtag actgcgatgt tcagaatgtt tcgactcaca taggaaggta cactcatggt
     9481 atgctttagc cgtactgata cggtcattta tagtcatctg gaggaaagct ggatctcttc
     9541 aaatcccgtg gagcattatt tcgcgcctca gtctgtatat ggcgacatga atagtccagc
     9601 tgtactgaaa gacaacgtgg tgtaccagtt tggtaaaaat cttcttgtct tggagttggg
     9661 atcaatagta tccctgagaa gccagtgggc caaagaaaca ttcttaccgc agataccaga
     9721 tcgattgcta tcagtcaggc ctggacgcag gtcgagcacc cccttgcgta tcgtatgaga
     9781 tagcttggcg gtgggtaaat gagtgagaga atggagaatc ataacgaaga ccattcgaga
     9841 catatcctgc aatcggtaac aagtacggct tatatgtgtt tagggacctt gaatcaattt
     9901 tgctgtctac cagattgcca tacgctggac ggatgatatg gaagccttgc caacctacct
     9961 cgaaagtttc tggcatagtg gaggaggtac catgggaatt tcaattttgg ttatgctgtc
    10021 cgtaagtgac atgagccggt ctcaactcga cttcgcccat accatgtgct gaatcgttga
    10081 cagacattcc tggccttggg aacaatattc gtctacagaa tctggctgca tccgctctca
    10141 gggtttcccg gccccaagtg ctgctctgtg tcttcgatac ctgttgcatg ggctcagtta
    10201 cgggggcgga atcatgaatt tgtctcttcc ctccatagaa agtacggaag tgttgttcgt
    10261 atcagcccga gtgagctttc cttcatctcg ggagcagcat ggaacgacat ctattcgcga
    10321 agcaagggta gaccggcctt ggagcgtgat cggacattct tcaatgacat gttagtcgac
    10381 ccggagacaa ttaccatggc taacgaggcc acgcatagtc ggataaggcg cgctatggca
    10441 ccggcctttt cacctcgcgc cctcctggag caagaaccca tcatccaagc caatataaag
    10501 ctgctcatgg ataagctcga agctcgggca gggagtggag gagctcccac ggacctgcga
    10561 gcatggttta actacaccac atttgacctg attggcgacc ttgccttcgg ggaatcattt
    10621 ggctgcctgg ccacctccac ctgtcatgaa tgggtgcagt ttgtactgga ccacttctac
    10681 acatctacgc ttctacatgt ggtgcaccgg ttccatccat tcaaccgagt actggccgcg
    10741 ctgttgccaa aatcactaat cgaaaaacga aaggcacatg acagtatgac tttgacaaag
    10801 gtgcatcgtc gactggaggt gcaaggccgg cgaaatgatt tcacacagca cctgttggat
    10861 gcagcagagg cgggcaccct atcgtcccgg gaggtagaaa aacaggcgag tgtcttaatc
    10921 ctagccggaa gtgaaactac atcggtggca ctcacctttg cgatatacct cgtattgaca
    10981 aacaaaccgg tcctggatca actgaatgat gagctgcata gcactttcaa agaggagcag
    11041 gagatcaatc tgctgtcggt taatcaattg aaatacctcc atgcggtgat tcaagaagct
    11101 ttgcggtttt gtccccctat ttccaacgga tttccacgac agactcctcc acaaggagct
    11161 acagttgacg gaatgtttat accaggcaag gtagatcagt tgccatgtta tttctgtgag
    11221 agacaagttt tctaatccac tcattgtaga ccgttgtcaa cataaaccac tgggctgcct
    11281 atcggtcccc tcgaaatttt actctccccg agcaattcct accagagcga tggctcggag
    11341 atccacgttt cgacgaggac gctaaagatg tatttcagcc gttttccgtt ggccctcgaa
    11401 actgcattgg aaagaagtta gtctctattt gcttactttg aactgcaacg tcgacactaa
    11461 tctcccttca ggtttgcgta tgacagcatg aagctcatct tagccaaatt tctgtggaga
    11521 ttcaaaccca ctctgctgga caaaagccga agctggctgg cccatcagcc aacctttgta
    11581 tcctttcacc agccgccatt gttggtagac ttggaaatca agggcagtga cgctttccca
    11641 gtccgtgaat gatggagatg gttatttgtg aagacatggc tcgctctaac tcgagctttc
    11701 agctgccaac ttgcagtacg ctttgagatt tgccagatgt atctcctgtt gacagatttg
    11761 taatatctcc agatgttgac gacgacccaa gttacaagtt acatgccgct tgactctgta
    11821 tcagatatgt tccttgaagg cagaaaacat cttgaaaatg tttaagatca agtatcatac
    11881 atagtaatct aaaattgctc agactaaggt gaagtgggtg ccactattga caggtctgtc
    11941 atggttgcaa tggatggaat acttctccct ccccattgag aacgccaggt attacgatta
    12001 cagtaagcca caacgtagtt tatagcccat agctgcttat gtggatgtga gatcatttgt
    12061 gatacaaatt ggtcgagtaa accatgtacg ccgttgctat cggcgctatt attggtataa
    12121 taagctatct gctctagttg tatttaatcc attcgttcaa ttgtattcat gccttttgaa
    12181 tccgtacgta ccgtacggta gagtttagag ttctaagaat attccaggga agtgcaagcc
    12241 caagcaaggg ggctggagtg atcgcctcga tctgacaggc gcttgtgcac ttatcaatgg
    12301 cagaggtatg caggagaatg ctactttaac atggtatcag agtaaagatt gcctcaaggc
    12361 aaggggcttg cttgtcatct cgacatcata cgggatatgc aggtgtggag caagaacaac
    12421 gcctccttgc gtctatagta tgcaagtgct caccgcagaa cgaggtgttt ctctccagga
    12481 caatcttgca catttctcaa ttcccaaagt atatttgcct tgaggatatg cagggtgcaa
    12541 agataggccc tcacctctaa tcttggaata ttttccttcc gccacactaa agggagttga
    12601 aatcaaacac ctggagctta acttcccagc cacttagctc attaatcttg ttctttatct
    12661 tttatggtca aaacagagac attggtccta tactagacta catttccaag agatcatgac
    12721 gggaaacgag cagaaattct cgctccaggg caaggttgcc attgtgaccg gtgctgggtc
    12781 cggaattgga agagaaacgg cattgtgtct cgccaatgct ggggcaaatg tagtcgtggc
    12841 tgaagctaat gaaacgacgg gcaaggagac tgcggccaag gtttccgcac aaacaggcag
    12901 tcgaggcctg tttatcctga ccgatgtgtc tcggagcgaa agcgtccagg ccatggtcat
    12961 cgccaccatc gaggcctttg ggcgtctcga tattgcagtg aacaacgccg ccctgcaccc
    13021 agacgcatcc cctatcgcag aactccacga ggatcactgg cagaagatca tcggggtgaa
    13081 ccttgtgggc gtcgcattct gtctcaagtg ggaacttcag cagatgatcc agcaaggggg
    13141 tggtggctcc attatcaaca tcagctctgc cacaatcaac cggccccaag aaaaaatgtc
    13201 agcgtacatc gccgcgaagc acggtatcac tggtttgact cagacggctg ctgtcgagaa
    13261 tggacgacac ggaattcggg ttaatgcgct cgccccaggg ggggtggcca ctgatctgac
    13321 gatggcgacc atgcaggaat tagggctcac cgaggaaaac gaggcggccc ggagtagcct
    13381 cttcaaacga ttcgcgaagc ccgaagaaat cgcgcaatcg gtactttggc tagcatcaga
    13441 tgctgcttcg tacgttactg gggccactat tgccgtggat tcaggactgt cgttgatttg
    13501 aatgtcaaat tctattctta tcgagagtcc catactttac ctgagcactt ggaaatacat
    13561 gatagttttc gttcctaata ttctctctgc tactagaagt tccctcggaa tatactatta
    13621 ttgtttcacg gtggactgac gagctattgg tattactttt agcgtagcat ctactagtta
    13681 caacccaagc tccatagact tctgggtcat actttaccga acaagtttgc caacgtaaac
    13741 aacccagtga agggagagac agcatgacgg ttttgagctg aagttcgaat ttggaaatgg
    13801 tacagagcgc aaaagttggt ctcggagaaa gcataccata ttgaccttct caaagtacta
    13861 ttggcatcca cagagatata gtgcaaagaa aagaataaga taaggaaatg tccctcgtct
    13921 ttcagtagcg ctcaaatgct ttacctatat catcgagtac agtatcaaga tctttgtcgc
    13981 gttcctgaaa gaggcgttct atgatgagcc tacgatcatt gctgaccggg tgccacgaca
    14041 ccgggaaaga gcgcggcttg atgagtgctc cctgatgctc tgtcccaggg tcccggctct
    14101 ttccatggtc agtccctgca ggacttctga aatcgaaggc ccatagcaac ttcggaatga
    14161 gtgtctctag agacataagc gctaatcgac gtcctgcaca cgctcgtcgt ccatatccaa
    14221 acacaccgag aggaaggtcc gggcgctcaa tccaacgttc gggacaaaac tgatccgcat
    14281 gctggtaagt atcctcgtcc atgtgccccg accagtagtt gaaaatgacg gtagagcctt
    14341 tcgggatatc atatccctgg tatttgtcgt cttcaagcgt aaaatgggga agtccctctg
    14401 cagttatcgg cctccagcgg aggacttcct ggatgaaagc tttgacatac ggtagctgtg
    14461 ggaggtcctt cggagtgggc agccgcgcgg agcccaccac tttgtctagc tcctggcgtg
    14521 cttttgtgac agcatctgga tagagggtac atgctagtac aaagaagtgt aagaccgtgg
    14581 cggttgagtc tactcctgcc tcaaaaagca cgccgatcag atattgcatc tcagatacgg
    14641 agaggttgcc agtatcttca ttgaactgca catgtttagt ccaattccac gagttgcttt
    14701 tcactgcagc ttccgagttt cgacgaaacc agcccatcgc acgtcgatga aagtcgtcgc
    14761 ccactgcctt ccatggtgcc aggcgacgcg gcagacagtt taagatcggg aacaaatcca
    14821 cgacccacgt tgcgttggta agtgtctggg taaaatgatc ggctaactcg aggatttcgt
    14881 ggaaatcaga ttcgttttgg tctgggtcct tgccatacgc aagggtataa atgatgttga
    14941 atttgaaccg attaaagcaa gtcactaagc tctctgtgct caacagctgg tataggactt
    15001 tacaactctc aatatccagg agactctgat agctcctgat cttggggccg ccaacaagcg
    15061 agagttggat tcgattatgt atcttccact tttcacccca agggagagta gaggtttgca
    15121 tctgcttggt catgcaatcg cgagccatga ccatgcgcgg tcgagaacca tacttgaggc
    15181 ttcgtttgcc aaagagttcc ttggtgacag ctatgtttcc caaaatgacc accgagctcc
    15241 atccaaactt caaacttatg atagggccat gcttcttgtg ccattgggct agaacatgac
    15301 gtctatcatc actcggtagc tgatgaagat tcccgatcaa tggcaaagtg ggtggaccgg
    15361 gaatgagagt gctggttaca tatttcccgt ataaaaagag cagaattata gtcccaatgg
    15421 ctactggcaa gaggaatgta gccattgtat tgattcgtcc tgctatattg ggaagggtag
    15481 ggagcatctc cgctgtcaac cctggtgata tttattgcat gaatgcgatc atctataaaa
    15541 gtaagaatag aatgtctcca cgatacgatg atctccaatt gactggtcca attgtaagac
    15601 cccctccact gaatattact tccacagtgg atatcagcca aagccacctt cttgcaaggg
    15661 gtccactgtg gatataggtt tggagagatc acacctttgt gatcgcgaac gcaaggggtg
    15721 agaaacattg ttcaggaatg gccttgttcg aaaaacaagg aatacatgca taggacttgt
    15781 cactttttgc tgtaaccgta atttctactg tcgaatcctg caagagagga ccaatcagcc
    15841 catgaagcca caccgctacg aaggttgcag tggtaaacat tatcgaaaca ctatcgtggc
    15901 ccttggatca tggattgcgc tctcaggtag gtcttctagc ttcagcagtt aactaacact
    15961 tatccatgga gttccctctt acgcattata gaatcgaaac taaatatatc tgatactcta
    16021 ctgtccgctt tttttccatc tctacttgtg ccaaacacag atataaatcg gagaaatggg
    16081 agaacaaacc gaatttgagc caattcaatt gagtcctctg gaccaggcaa tcccaccggt
    16141 gtacatccgg attcttctct gcttctccgt ggtaaatgtg gatagagcaa tctcccagct
    16201 gcagactgga gtatcttccc ttctctcggc gttgcctttt ttgtctgggg atgtcgtgcg
    16261 atacacggca ccaggcaaga caaaatggct ctatcaattg tgtccaccta cacaccaggt
    16321 gcaggcgact ggcgtactag ttgttaaaca ccatcagatg cgttgtatgg ttgacgagaa
    16381 gagattcgca ccctcatcga catcacatat cccgctttcc ccattcgcgg aaccggcgag
    16441 accagcccca attttccgcg tgcaagcgaa tgcatatatc gacgggatta ccctcggatt
    16501 tgcctttcat catattgctg tggatgctac tgggatgggg gttattatca gtgaactcgc
    16561 acgacattgc cggagcagtc ctccgcccag tctattatgt ccagactacg aaagagcaac
    16621 gcgtcagctc attagcaact cgcgagctac ggaatgctcg gggctggatc acagtggtga
    16681 ttatatctca tgtcaggcct tatctccccc tgcggagggg tctgaggacg cttcaccatc
    16741 gatcgagatc tcaactgaaa ccagaacgtt tgtgttccca gctgctcgac tagaatctct
    16801 caaaaatgcc tgcattgaga tgctaccaac gcttgaccaa cagcaacgac aacagaatcc
    16861 atgtctggat gagcccgcgc gcactaaagt cccatggctc tcaacaaacg atgtctttgt
    16921 cgcactttta tgggtgtgtc taaccaggtg ccgctatcag gaggaccaga atagcgggtt
    16981 gccgagtgat gagcacaccc gtatatgcat gggcgtcaac atgcgtagcc gcattcagcc
    17041 tccgctttca gctgattatc ttgggaatgc gattctctct ctctctttca aactcaatgt
    17101 gaacgtcttt cgtcgcactc aggtgacgaa tgagagtatt gaaggagtag actccaaaga
    17161 catagagcat aaacaatggc tggccacgat ctgtcgagtt gctcgtaaca tccggagagg
    17221 agtgaatgga atggacgatt catatttccg tagcgttgtg agctttctcg aagatagttc
    17281 ggattgtcgc ctctttgact atgccaggtg cgacttttgc gtgcccagtt ggcgccactt
    17341 atgtgtgtat catgccgact tcggggaaat gggaagacca aagagcctgg aagtctttga
    17401 cgtgcctgga gatggttcct tttgtatcct gcctcagcac tatggtgctg ctgctccctg
    17461 ggaggtgtgt tttagcgtga attctcaggt gttgggtcgt ctgcgccgtg acccaatttt
    17521 gtcacgctac atctctcatg aaaattgatt ttagctattg ctaggcttgc taaaagccta
    17581 gtactcttgt cactagcgct tgcttttgaa gatttaggga acgatatata tactgaccat
    17641 tgacatctag aacgacaaat gcctaactga aactacgggt actagtacaa tcattccatt
    17701 ctgttggtaa tcagtcatat tctcactgag aagcagaagg gcattcctat aagtctgttc
    17761 ttctcacatt gttatagctg aactccggta tgcatgaacg tgtatccgtt gtagaggatc
    17821 ttggaagttt gttgatccaa attaccgaat gaacaaaagg cagagataga ctagaatgct
    17881 atgtagatta ccaggtatag gctgtgaaca tctgccatcc atgacaggtg tcttcatcct
    17941 ccaccttcca tctatttact tgttgcggag cattcttgtt ttgctgagga ccgaaacata
    18001 acatgggtca ggtttacata accagcaagg gagacgcaag ggctcctgaa gtgcatttta
    18061 tattgtctca tgctggctct cttgtgtatt ccctgtatga cccaaattaa ctctttttca
    18121 aactcttctt tcttttggca cccctcctcc gctttagtgc caccggtctc cactgccttc
    18181 gtgactagcc acgatgactg atatctcgac tggtgttcag ctcaagccag ggataggaga
    18241 tggcaccgtc tacaatggta acatgtccaa ggatactttg gtgaactgta gccctgatcc
    18301 agaaaatcca gaaaaaggac aagcaagctc accaagaact caaatttcag tcgacgacaa
    18361 tgaggaatcc acgacagaat atccatcctc ttggaagctg gccatgatta tgatcagtct
    18421 atgccttgcg gtcttctgtt tggcactggt gagccattcg aacgtcattt atacctctgc
    18481 gcgtgatttg gctgggctga ctgtttggta tcttatagga tacgacgatt atggccacag
    18541 cgatccccaa gattgctgat cagttcaact ccttaaacga cgtcgggtgg tacggcagcg
    18601 cctatctcct cacaaccagt gctttgacac tcagttttgg aaagctgtac agcttctatt
    18661 cgatcaaatg ggtttatctg caggcacttg gtatgtttga gatcggctcc ctgatctgcg
    18721 gtgccactcc caattcactg ggattgatca tcggacgtgc tattgccggc tccggatccg
    18781 cgggcatcta ctctggatcg atgctgattg tcgcgcggtc tgcgccactg gaacgaaggc
    18841 cgcttttgac cggcatactg ggcggcctgt tcggcgttgc cagcgtggtt gggccgctca
    18901 tcggcggtgc attcacggac aatcttagct ggagatggtg cttctatatc aatttacccc
    18961 tcggagccgt tacgggacta ttcctcatat tgttctttga tggagccaag gcgaccaccc
    19021 agcgcgctac gatcagggat caactatcgc aacttgacct gctagggtcc ctttgcttct
    19081 taccagctat catctgcgtc ttgttagcac tgcaatgggg gggcacgaca tatccctggc
    19141 atgacggccg tattatcgcc ttattcaccg tctttggggt tctactcttg gcctttgccg
    19201 gggtccagtg gtggcgacag gagaaagcta ccgtacctcc acgcctgatc gcgaaccgga
    19261 atgtgtgggg agctgcactt ttctctttct gtctcaatgc gtcctttatc atcttcacct
    19321 actatgtaag tcccagccca atgcgctttt gttacactat ttactaagag atttccagct
    19381 cccgatgtgg ttccaaagca ttaaaggtgt cacggcaacc caatccggca ttatgaacct
    19441 cccgatggtg ctagcagtgg tgattttctc cattatctcc ggcgggctag tcggagccct
    19501 ggggtactat acaccgttca tggtgatcgc acctctgatc gcagccattg gggccggact
    19561 actctccacc cttcgaatgg actccaacaa cgcgtcctgg atcggatatc aaatcttata
    19621 cggtgtcggt gtaggctgtg gacttcaaca gcccatcgta gcagtgcaag gctcccttgc
    19681 ccccgccgat ctacccaccg gcaccgtgat cgtaatgttc atgcagacaa tcggtggcgc
    19741 catcttcatg tccgtcggcc agaacgtatt ccaaaaccaa ctaatgcgaa acttggccac
    19801 gcaagctccg agcgtcgatg cggctagagt gctccaggct ggggcaacta tgttgcggaa
    19861 aaccgtctcc agtgatttgc ttccagccgc gttgcgcgcg tataattcgg ccatcaccga
    19921 ggccttctat gttgctgtgg ctatggctgt gcttgcgctt cctggggcgt tggttatgca
    19981 gtggatttct gttaagggtc gacagctcta gattgggaaa ggggggaggt ggtattaggg
    20041 ctactttttt ggcttgcatt tttttgttac cgctagatct gttgatttaa taggtggggg
    20101 tggattttcc gttatcaatt aatgcatttc cagctatatt tagagtttac tcaatttcaa
    20161 tagatcactg tatttccact gtatgaaata cagtaatgac acaattggga tacctggtac
    20221 atacatacat acatacatac atgcatgcat gcatgtatgt atgaccagtc ttcgggcaaa
    20281 aaagccacat atgcgatgca ttgccaacaa gtaagggagc cagacatgag tgatctgcac
    20341 aatccatttc cgaatgtagt caccaggaca aagtgacaaa gtgacaaagt gtcaatgtta
    20401 tcaagcccat ccccaaaaag aatatcatac atagaacctg gctgagcggt gtgtccatac
    20461 catctaacca tctacccaac caactcactc cacaacaact gcctcactat catgacacgt
    20521 cagagtcact atcaagcaat cattctagac ctaggaaatg tggttttcga atgggacact
    20581 tcccagaatc cccccactgc agccccaaac caaatatctc tgttacgcac cagcatgaag
    20641 tcccccgttt accattccta cgaacgaggc cagctctcaa cagaagaatg tcatcgctta
    20701 ctcggggaat ccctccacgt tgaccccggc caaatcaaag aagctttcga tctcgcccgc
    20761 caaagcctcc gatctaaccc cgcgctcctg gacttcatcc ggcagctgaa gcagacgcgt
    20821 ggagtggccg tgtacgccat gtccaacatc ccgcaggccg agatcgagta tctgaaagag
    20881 agcagagcag gcgacatgga ggtcttcgac gaggtctttg cctcggggta cgtggggtcc
    20941 cggaagccgg agacggagtt ttatcggcgg gtgatggggg agataggctt gaaggctgag
    21001 cgagtggtct ttgtggatga taaggaggag aatgtggatg tggcgcgtgg gttggggttg
    21061 tatggggttt gctttggggg ggtggaggag ttgcggggac atcttcttgg gatttgattc
    21121 gtatggataa tcatggtcta tggaatacgt agatatagaa tagaagatat gttgatatca
    21181 atcagtctcc tgtggtacat tccggggatg caacttcaac cacagaggcc ccttctccca
    21241 tacgatgtag ctcttggaat ttgcccagtc tgctgaacgc tcatccagct ggacgtcgaa
    21301 gtgccacagg atcttggcca gaattgtgcg catttctgcg tatgcgaggc tggggtgatt
    21361 gtaagccagc agctaggagc cattgaagaa aaggaacgaa cttactttct tccaatgcaa
    21421 gcacgcggtc cataggagaa cggctggaga gccatcgtct gatcggaggc gaactcactc
    21481 tctgcgtcac gatcaagcca tctctgcggt aggaattcat taggtctggt gaaattcctg
    21541 gcgctacgga aggttgagta gtggcccaca gacacagaga cctttggcac aaaccgacca
    21601 tggttagctt tttcttcatc taactagaaa gcaaaatgga agagcgactt acgccacccg
    21661 gcacatagcg accgcagatt cgggcacccc ctttcgggac gactcgtggg ccgatccctg
    21721 gtgctggagg gaagagacga aggctctcct cgatgactcc gttcatgtat gggagctgag
    21781 cagctgatag aaaattgata tcggtctctt gggtgaaggc ggagcggata tcttggacga
    21841 gtcttcgatg gcacgcggca ttcttctgta ggaagtagag acacgcagct agcacggtgg
    21901 cagtggtctc gctgccggct tgaattagga gggctgcgtt catctcaatc tcgggtgtac
    21961 tcatccctcg gtcgtcgttg tatttgagga tgtaggagat gaagtccggc cgcgacgttt
    22021 cggtttgcaa ccgccgtgtg actctgtcct tgctcatctg gtaatgcgca atccgcttct
    22081 gaacgagact cttggggagg aacctccgga tgaagcctaa caagatgggg tatatattca
    22141 aagcccggag gatggcccca gtcttgatac ttttgaagat ggttgcaacc cagggatgat
    22201 attcagagtt ctgaagacag ccaaatggct ccccaaatgc aaggtcgcca ataatatcga
    22261 atgtcagaaa gttcagccac tcctccatgt tgactgtctc ggcccccata cgtgcctgtc
    22321 ctcgaagcct ttggatgaag agatcaatat agcccatgat gaggtgttcc tgctggcgca
    22381 gcgatcgctc ggaaaatgca tggttcagga gccgtttctg ccgagtatgg tccttctcat
    22441 tggcgttgat catatgcgac gagcctgcct gggctggcat gaagaattcc ggatccttgc
    22501 tgaaaggcag ggtgcccggc tttcggtgac cgtagatgtc tgtccaggcc tcgggcgtcc
    22561 ggtaagttag ggcattgggc cggatccgaa tgacgtcccc gtacacttta tgaagttcct
    22621 ggaggcgcag gtgcagattg cctgtgcacg tccaggcaaa atatggtaga ttggagacag
    22681 cggcgagccg tgggcccgga tatcctgaca acggatggag ccatagtcga tacaccatgc
    22741 gccagagtcc ccaggcaatg ggctgttttc cgatgagtta gccttgataa cttttaaaga
    22801 ggggaatcag cccttaccag tgtcaatata gctaaccatg aatgcatagt ggcatgagta
    22861 gagccgagga ccgaagttgt catcccagcg tgaaagcttt tttactacag tcaagagaat
    22921 gtaaggataa gcacacttaa cagcccattc tatgccaaca gccttctgaa ccaatccaca
    22981 caggtcaggg cttttaagta tttccaagca tttctccgat acgatatttg gcactgatac
    23041 gctcacgttt cggtgcgaac aagcggtctg cattccagcc gctcgcacct gcagcaggct
    23101 agggccccga tccacagaat ggacatgtcg caagggatta gaattggaaa ttgtaaattg
    23161 acgtggcaga aagtcgaagc gggtctgacg gtgaagaaga tttgacagta tttattgata
    23221 ggcttttctt tctgtgtgtt ccttcccact agcttcatgg tcttgctcac cacgaaacca
    23281 acatgtgcac taccttcaag gctgccatct tcgatatggg aggagtcctt ttcacctgga
    23341 acccgatcgt cgacacgcaa gtatccctca aggatctcgg aaccataatc aacagcgaga
    23401 cctgggagca gttcgaacgt ggaaagatcg agccggacga ttgttatcac caactgggat
    23461 ctcagattgg gctacctgga tcggaaatcg ccgcgacat
//
