BGC0001522: auroramycin biosynthetic gene cluster from Streptomyces filamentosus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 126,292 nt. (total: 126,292 nt).
This entry is originally from NCBI GenBank MH101993.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001522
Short description auroramycin biosynthetic gene cluster from Streptomyces filamentosus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MH101993.1
via
Compounds
  • auroramycin
Species Streptomyces filamentosus [taxonomy]
References
Chemical products information
auroramycin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWR88379.1
 1 - 1829 (-) hypothetical protein
    copy AA seq
    copy Nt seq
    • AWR88380.1
    		 2122 - 3504 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • AWR88381.1
      		 3531 - 4901 (+) hypothetical protein
        copy AA seq
        copy Nt seq
        • AWR88382.1
        		 5326 - 6141 (+) hypothetical protein
          copy AA seq
          copy Nt seq
          • AWR88383.1
          		 6322 - 7029 (+) putative GntR family transcriptional regulator
            copy AA seq
            copy Nt seq
            • AWR88384.1
            		 7214 - 7495 (-) hypothetical protein
              copy AA seq
              copy Nt seq
              • AWR88385.1
              		 7592 - 10519 (+) putative GCN5-related N-acetyltransferase
                copy AA seq
                copy Nt seq
                • AWR88386.1
                		 10577 - 11173 (+) hypothetical protein
                  copy AA seq
                  copy Nt seq
                  • AWR88387.1
                  		 11173 - 12360 (+) hypothetical protein
                    copy AA seq
                    copy Nt seq
                    • AWR88388.1
                    		 12407 - 13057 (+) hypothetical protein
                      copy AA seq
                      copy Nt seq
                      • AWR88389.1
                      		 13082 - 15976 (-) putative LuxR family transcriptional regulator
                        copy AA seq
                        copy Nt seq
                        • AWR88390.1
                        		 16258 - 17244 (-) putative NAD-dependent epimerase/dehydratase
                          copy AA seq
                          copy Nt seq
                          • AWR88391.1
                          		 17267 - 18490 (-) putative nucleotide sugar dehydrogenase
                            copy AA seq
                            copy Nt seq
                            • AWR88392.1
                            		 18682 - 19362 (-) hypothetical protein
                              copy AA seq
                              copy Nt seq
                              • AWR88393.1
                              		 19662 - 31130 (+) putative beta-ketoacyl synthase
                                copy AA seq
                                copy Nt seq
                                • AWR88394.1
                                		 31162 - 32499 (+) putative crotonyl-CoA reductase / alcohol dehydrogenase
                                  copy AA seq
                                  copy Nt seq
                                  • AWR88395.1
                                  		 32496 - 33506 (+) putative 3-oxoacyl-(acyl carrier protein) synthase III
                                    copy AA seq
                                    copy Nt seq
                                    • AWR88396.1
                                    		 33503 - 34363 (+) putative 3-hydroxybutyryl-CoA dehydrogenase
                                      copy AA seq
                                      copy Nt seq
                                      • AWR88397.1
                                      		 34440 - 35423 (+) putative glycosyltransferase, MGT family
                                        copy AA seq
                                        copy Nt seq
                                        • AWR88398.1
                                        		 35485 - 40416 (+) putative beta-ketoacyl synthase
                                          copy AA seq
                                          copy Nt seq
                                          • AWR88399.1
                                          		 40544 - 51436 (+) putative beta-ketoacyl synthase
                                            copy AA seq
                                            copy Nt seq
                                            • AWR88400.1
                                            		 51457 - 52224 (-) putative TetR family transcriptional regulator
                                              copy AA seq
                                              copy Nt seq
                                              • AWR88401.1
                                              		 52320 - 53330 (+) putative ABC transporter ATP-binding protein
                                                copy AA seq
                                                copy Nt seq
                                                • AWR88402.1
                                                		 53327 - 54124 (+) putative ABC-2 type transporter
                                                  copy AA seq
                                                  copy Nt seq
                                                  • AWR88403.1
                                                  		 54207 - 54983 (-) putative thioesterase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • AWR88404.1
                                                    		 55358 - 71611 (+) putative beta-ketoacyl synthase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • AWR88405.1
                                                      		 71617 - 82992 (+) putative phosphopantetheine-binding domain- containing prot ein
                                                        copy AA seq
                                                        copy Nt seq
                                                        • AWR88406.1
                                                        		 83195 - 84391 (-) putative cytochrome P450
                                                          copy AA seq
                                                          copy Nt seq
                                                          • AWR88407.1
                                                          		 84388 - 86028 (-) putative AMP-dependent synthetase and ligase
                                                            copy AA seq
                                                            copy Nt seq
                                                            • AWR88408.1
                                                            		 86170 - 86409 (+) putative acyl carrier protein
                                                              copy AA seq
                                                              copy Nt seq
                                                              • AWR88409.1
                                                              		 86493 - 88169 (+) putative AMP-dependent synthetase and ligase
                                                                copy AA seq
                                                                copy Nt seq
                                                                • AWR88410.1
                                                                		 88111 - 89100 (-) putative malonyl CoA-acyl carrier protein transacylase
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • AWR88411.1
                                                                  		 89191 - 90585 (-) putative aminotransferase
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • AWR88412.1
                                                                    		 90606 - 91952 (-) hypothetical protein
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • AWR88413.1
                                                                      		 91987 - 92904 (-) putative haloalkane dehalogenase
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        • AWR88414.1
                                                                        		 93108 - 94403 (+) putative glycosyltransferase, MGT family
                                                                          copy AA seq
                                                                          copy Nt seq
                                                                          • AWR88415.1
                                                                          		 94551 - 95621 (+) putative glucose-1-phosphate adenylyl/ thymidylyltransferas e
                                                                            copy AA seq
                                                                            copy Nt seq
                                                                            • AWR88416.1
                                                                            		 95618 - 96667 (+) putative NAD-dependent epimerase/dehydratase
                                                                              copy AA seq
                                                                              copy Nt seq
                                                                              • AWR88417.1
                                                                              		 96664 - 98028 (+) hypothetical protein
                                                                                copy AA seq
                                                                                copy Nt seq
                                                                                • AWR88418.1
                                                                                		 98097 - 98825 (-) putative methyltransferase
                                                                                  copy AA seq
                                                                                  copy Nt seq
                                                                                  • AWR88419.1
                                                                                  		 99031 - 100023 (+) putative glycosyltransferase, MGT family
                                                                                    copy AA seq
                                                                                    copy Nt seq
                                                                                    • AWR88420.1
                                                                                    		 100058 - 101326 (-) hypothetical protein
                                                                                      copy AA seq
                                                                                      copy Nt seq
                                                                                      • AWR88421.1
                                                                                      		 101465 - 102781 (+) putative cytochrome P450
                                                                                        copy AA seq
                                                                                        copy Nt seq
                                                                                        • AWR88422.1
                                                                                        		 102804 - 104093 (+) putative glycosyltransferase, MGT family
                                                                                          copy AA seq
                                                                                          copy Nt seq
                                                                                          • AWR88423.1
                                                                                          		 104090 - 105106 (+) putative oxidoreductase
                                                                                            copy AA seq
                                                                                            copy Nt seq
                                                                                            • AWR88424.1
                                                                                            		 105096 - 106286 (+) putative DegT/DnrJ/EryC1/StrS aminotransferase
                                                                                              copy AA seq
                                                                                              copy Nt seq
                                                                                              • AWR88425.1
                                                                                              		 106383 - 107720 (-) putative ABC transporter, permease component
                                                                                                copy AA seq
                                                                                                copy Nt seq
                                                                                                • AWR88426.1
                                                                                                		 107724 - 108536 (-) putative ABC transporter ATP-binding protein
                                                                                                  copy AA seq
                                                                                                  copy Nt seq
                                                                                                  • AWR88427.1
                                                                                                  		 108956 - 109300 (+) hypothetical protein
                                                                                                    copy AA seq
                                                                                                    copy Nt seq
                                                                                                    • AWR88428.1
                                                                                                    		 109387 - 110163 (-) hypothetical protein
                                                                                                      copy AA seq
                                                                                                      copy Nt seq
                                                                                                      • AWR88429.1
                                                                                                      		 110400 - 111230 (+) putative rhodanese domain-containing protein
                                                                                                        copy AA seq
                                                                                                        copy Nt seq
                                                                                                        • AWR88430.1
                                                                                                        		 111315 - 112772 (-) hypothetical protein
                                                                                                          copy AA seq
                                                                                                          copy Nt seq
                                                                                                          • AWR88431.1
                                                                                                          		 112822 - 113994 (+) hypothetical protein
                                                                                                            copy AA seq
                                                                                                            copy Nt seq
                                                                                                            • AWR88432.1
                                                                                                            		 114080 - 115399 (-) hypothetical protein
                                                                                                              copy AA seq
                                                                                                              copy Nt seq
                                                                                                              • AWR88433.1
                                                                                                              		 115359 - 116603 (-) putative major facilitator transporter
                                                                                                                copy AA seq
                                                                                                                copy Nt seq
                                                                                                                • AWR88434.1
                                                                                                                		 116755 - 117927 (+) hypothetical protein
                                                                                                                  copy AA seq
                                                                                                                  copy Nt seq
                                                                                                                  • AWR88435.1
                                                                                                                  		 117978 - 118778 (+) putative inositol monophosphatase
                                                                                                                    copy AA seq
                                                                                                                    copy Nt seq
                                                                                                                    • AWR88436.1
                                                                                                                    		 118871 - 119044 (-) hypothetical protein
                                                                                                                      copy AA seq
                                                                                                                      copy Nt seq
                                                                                                                      • AWR88437.1
                                                                                                                      		 119427 - 120080 (+) putative response regulator
                                                                                                                        copy AA seq
                                                                                                                        copy Nt seq
                                                                                                                        • AWR88438.1
                                                                                                                        		 120086 - 121318 (+) putative sensor histidine kinase
                                                                                                                          copy AA seq
                                                                                                                          copy Nt seq
                                                                                                                          • AWR88439.1
                                                                                                                          		 121722 - 122018 (+) hypothetical protein
                                                                                                                            copy AA seq
                                                                                                                            copy Nt seq
                                                                                                                            • AWR88440.1
                                                                                                                            		 122032 - 122994 (+) hypothetical protein
                                                                                                                              copy AA seq
                                                                                                                              copy Nt seq
                                                                                                                              • AWR88441.1
                                                                                                                              		 123045 - 123503 (-) hypothetical protein
                                                                                                                                copy AA seq
                                                                                                                                copy Nt seq
                                                                                                                                • AWR88442.1
                                                                                                                                		 123712 - 124146 (+) hypothetical protein
                                                                                                                                  copy AA seq
                                                                                                                                  copy Nt seq
                                                                                                                                  • AWR88443.1
                                                                                                                                  		 124280 - 124672 (+) hypothetical protein
                                                                                                                                    copy AA seq
                                                                                                                                    copy Nt seq
                                                                                                                                    • AWR88444.1
                                                                                                                                    		 125158 - 125445 (+) hypothetical protein
                                                                                                                                      copy AA seq
                                                                                                                                      copy Nt seq
                                                                                                                                      • AWR88445.1
                                                                                                                                      		 125600 - >126292 (+) hypothetical protein
                                                                                                                                        copy AA seq
                                                                                                                                        copy Nt seq
                                                                                                                                        Biosynthesis information
                                                                                                                                        Annotation changelog

                                                                                                                                        Entry version: 4

                                                                                                                                        Date
                                                                                                                                        Changes
                                                                                                                                        Submitters
                                                                                                                                        Reviewers
                                                                                                                                        2022-10-07
                                                                                                                                        Update chemical activity to schema version 2.11
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                                        Entry version: 3

                                                                                                                                        Date
                                                                                                                                        Changes
                                                                                                                                        Submitters
                                                                                                                                        Reviewers
                                                                                                                                        2022-09-15
                                                                                                                                        Updated bioactivity data
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                                        Entry version: 2

                                                                                                                                        Date
                                                                                                                                        Changes
                                                                                                                                        Submitters
                                                                                                                                        Reviewers
                                                                                                                                        2019-10-16
                                                                                                                                        Migrated from v1.4
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                                        Entry version: 1

                                                                                                                                        Date
                                                                                                                                        Changes
                                                                                                                                        Submitters
                                                                                                                                        Reviewers
                                                                                                                                        2018-08-06
                                                                                                                                        Submitted
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                        Detailed domain annotation
                                                                                                                                        Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                                                                                                        A domain glossary is available here, and an explanation of the visualisation is available here.
                                                                                                                                        Selected features only
                                                                                                                                        Show module domains
                                                                                                                                        Similar known gene clusters from MIBiG 4.0
                                                                                                                                        Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                                                                                        Click on reference genes to show details of similarities to genes within the current region.
                                                                                                                                        Click on an accession to open that entry in the MiBIG database.