BGC0001522: auroramycin biosynthetic gene cluster from Streptomyces filamentosus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 126,292 nt. (total: 126,292 nt).
This entry is originally from NCBI GenBank MH101993.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001522
Short description auroramycin biosynthetic gene cluster from Streptomyces filamentosus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: MH101993.1
Compounds
  • auroramycin
Species Streptomyces filamentosus [taxonomy]
References
Chemical products information
auroramycin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWR88379.1
1 - 1829 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88380.1
2122 - 3504 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88381.1
3531 - 4901 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88382.1
5326 - 6141 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88383.1
6322 - 7029 (+) putative GntR family transcriptional regulator
copy AA seq
copy Nt seq
  • AWR88384.1
7214 - 7495 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88385.1
7592 - 10519 (+) putative GCN5-related N-acetyltransferase
copy AA seq
copy Nt seq
  • AWR88386.1
10577 - 11173 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88387.1
11173 - 12360 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88388.1
12407 - 13057 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88389.1
13082 - 15976 (-) putative LuxR family transcriptional regulator
copy AA seq
copy Nt seq
  • AWR88390.1
16258 - 17244 (-) putative NAD-dependent epimerase/dehydratase
copy AA seq
copy Nt seq
  • AWR88391.1
17267 - 18490 (-) putative nucleotide sugar dehydrogenase
copy AA seq
copy Nt seq
  • AWR88392.1
18682 - 19362 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88393.1
19662 - 31130 (+) putative beta-ketoacyl synthase
copy AA seq
copy Nt seq
  • AWR88394.1
31162 - 32499 (+) putative crotonyl-CoA reductase / alcohol dehydrogenase
copy AA seq
copy Nt seq
  • AWR88395.1
32496 - 33506 (+) putative 3-oxoacyl-(acyl carrier protein) synthase III
copy AA seq
copy Nt seq
  • AWR88396.1
33503 - 34363 (+) putative 3-hydroxybutyryl-CoA dehydrogenase
copy AA seq
copy Nt seq
  • AWR88397.1
34440 - 35423 (+) putative glycosyltransferase, MGT family
copy AA seq
copy Nt seq
  • AWR88398.1
35485 - 40416 (+) putative beta-ketoacyl synthase
copy AA seq
copy Nt seq
  • AWR88399.1
40544 - 51436 (+) putative beta-ketoacyl synthase
copy AA seq
copy Nt seq
  • AWR88400.1
51457 - 52224 (-) putative TetR family transcriptional regulator
copy AA seq
copy Nt seq
  • AWR88401.1
52320 - 53330 (+) putative ABC transporter ATP-binding protein
copy AA seq
copy Nt seq
  • AWR88402.1
53327 - 54124 (+) putative ABC-2 type transporter
copy AA seq
copy Nt seq
  • AWR88403.1
54207 - 54983 (-) putative thioesterase
copy AA seq
copy Nt seq
  • AWR88404.1
55358 - 71611 (+) putative beta-ketoacyl synthase
copy AA seq
copy Nt seq
  • AWR88405.1
71617 - 82992 (+) putative phosphopantetheine-binding domain- containing prot ein
copy AA seq
copy Nt seq
  • AWR88406.1
83195 - 84391 (-) putative cytochrome P450
copy AA seq
copy Nt seq
  • AWR88407.1
84388 - 86028 (-) putative AMP-dependent synthetase and ligase
copy AA seq
copy Nt seq
  • AWR88408.1
86170 - 86409 (+) putative acyl carrier protein
copy AA seq
copy Nt seq
  • AWR88409.1
86493 - 88169 (+) putative AMP-dependent synthetase and ligase
copy AA seq
copy Nt seq
  • AWR88410.1
88111 - 89100 (-) putative malonyl CoA-acyl carrier protein transacylase
copy AA seq
copy Nt seq
  • AWR88411.1
89191 - 90585 (-) putative aminotransferase
copy AA seq
copy Nt seq
  • AWR88412.1
90606 - 91952 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88413.1
91987 - 92904 (-) putative haloalkane dehalogenase
copy AA seq
copy Nt seq
  • AWR88414.1
93108 - 94403 (+) putative glycosyltransferase, MGT family
copy AA seq
copy Nt seq
  • AWR88415.1
94551 - 95621 (+) putative glucose-1-phosphate adenylyl/ thymidylyltransferas e
copy AA seq
copy Nt seq
  • AWR88416.1
95618 - 96667 (+) putative NAD-dependent epimerase/dehydratase
copy AA seq
copy Nt seq
  • AWR88417.1
96664 - 98028 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88418.1
98097 - 98825 (-) putative methyltransferase
copy AA seq
copy Nt seq
  • AWR88419.1
99031 - 100023 (+) putative glycosyltransferase, MGT family
copy AA seq
copy Nt seq
  • AWR88420.1
100058 - 101326 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88421.1
101465 - 102781 (+) putative cytochrome P450
copy AA seq
copy Nt seq
  • AWR88422.1
102804 - 104093 (+) putative glycosyltransferase, MGT family
copy AA seq
copy Nt seq
  • AWR88423.1
104090 - 105106 (+) putative oxidoreductase
copy AA seq
copy Nt seq
  • AWR88424.1
105096 - 106286 (+) putative DegT/DnrJ/EryC1/StrS aminotransferase
copy AA seq
copy Nt seq
  • AWR88425.1
106383 - 107720 (-) putative ABC transporter, permease component
copy AA seq
copy Nt seq
  • AWR88426.1
107724 - 108536 (-) putative ABC transporter ATP-binding protein
copy AA seq
copy Nt seq
  • AWR88427.1
108956 - 109300 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88428.1
109387 - 110163 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88429.1
110400 - 111230 (+) putative rhodanese domain-containing protein
copy AA seq
copy Nt seq
  • AWR88430.1
111315 - 112772 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88431.1
112822 - 113994 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88432.1
114080 - 115399 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88433.1
115359 - 116603 (-) putative major facilitator transporter
copy AA seq
copy Nt seq
  • AWR88434.1
116755 - 117927 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88435.1
117978 - 118778 (+) putative inositol monophosphatase
copy AA seq
copy Nt seq
  • AWR88436.1
118871 - 119044 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88437.1
119427 - 120080 (+) putative response regulator
copy AA seq
copy Nt seq
  • AWR88438.1
120086 - 121318 (+) putative sensor histidine kinase
copy AA seq
copy Nt seq
  • AWR88439.1
121722 - 122018 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88440.1
122032 - 122994 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88441.1
123045 - 123503 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88442.1
123712 - 124146 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88443.1
124280 - 124672 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88444.1
125158 - 125445 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AWR88445.1
125600 - >126292 (+) hypothetical protein
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.