LOCUS       BGC0001527              8170 bp    DNA     linear   PLN 30-AUG-2017
DEFINITION  Gelatoporia subvermispora strain B siderophore synthetase (NPS2)
            gene, complete cds.
ACCESSION   BGC0001527
VERSION     BGC0001527
KEYWORDS    .
SOURCE      Gelatoporia subvermispora
  ORGANISM  Gelatoporia subvermispora
            Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
            Agaricomycetes; Polyporales; Gelatoporiaceae; Gelatoporia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:45:36
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..>8170
                     /gene="NPS2"
     source          1..8170
                     /db_xref="taxon:42742"
                     /mol_type="genomic DNA"
                     /organism="Gelatoporia subvermispora"
                     /strain="B"
     mRNA            join(<1..1020,1138..1357,1419..1550,1606..1856,1909..1961,
                     2013..3266,3325..3934,3989..4276,4333..4983,5035..5814,
                     5868..6119,6177..7835,7891..7968,8024..>8170)
                     /gene="NPS2"
                     /product="siderophore synthetase"
     protocluster    1..8170
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:8170]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..8170
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..8170
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..8170
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001527"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8170
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             join(1..1020,1138..1357,1419..1550,1606..1856,1909..1961,
                     2013..3266,3325..3934,3989..4276,4333..4983,5035..5814,
                     5868..6119,6177..7835,7891..7968,8024..8170)
                     /NRPS_PKS="Domain: AMP-binding (268-670). E-value: 3.3e-94.
                     Score: 307.6. Matches aSDomain:
                     nrpspksdomains_NPS2_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (818-883). E-value: 3.3e-13.
                     Score: 41.9. Matches aSDomain:
                     nrpspksdomains_NPS2_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (922-1209). E-value:
                     6.2e-35. Score: 112.6. Matches aSDomain:
                     nrpspksdomains_NPS2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PP-binding (1368-1431). E-value:
                     5.9e-09. Score: 28.3. Matches aSDomain:
                     nrpspksdomains_NPS2_PP-binding.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1478-1762). E-value:
                     3.5e-36. Score: 116.7. Matches aSDomain:
                     nrpspksdomains_NPS2_Condensation_DCL.2"
                     /NRPS_PKS="Domain: PP-binding (1924-1986). E-value:
                     1.7e-09. Score: 30.0. Matches aSDomain:
                     nrpspksdomains_NPS2_PP-binding.3"
                     /NRPS_PKS="Domain: Condensation_DCL (2047-2320). E-value:
                     6e-34. Score: 109.3. Matches aSDomain:
                     nrpspksdomains_NPS2_Condensation_DCL.3"
                     /codon_start=1
                     /gene="NPS2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     261.9; E-value: 1.6e-79)"
                     /gene_kind="biosynthetic"
                     /product="siderophore synthetase"
                     /protein_id="AQX36215.1"
                     /sec_met_domain="AMP-binding (E-value: 7.7e-99, bitscore:
                     317.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.8e-15, bitscore:
                     41.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.7e-38, bitscore:
                     117.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHTRTDCDHPELPKLATVISGYRHCDLPDLSSDRFPASTTYSV
                     SACIKESLISTQVDVLDARAPFAVLVATIGRVLGAYCGCTDVILALTDQDCEDLRTARI
                     TWDENTQWADLLHTVLQSLSGDTSFRITVPAIREALGLTEKQAPCLALVRDAPSSDYDN
                     TDFPLVFNWDISTFTLRLFTSERHLHPSGADLLASQIASLLVPALTNPATQVFRLPDLQ
                     ADLLSIYEKLTFEDRCQAYSRVPPVRLATDHLTLRLASQANDVAVEWYGALADDHHPGT
                     SQPETMTFGEWHRRANQMARWLVARGLEKGDKVAVCMKRDTSYHVSLIAVLKAGACYVP
                     IDPELPSERQSYIACDSGARFVLVSSETASTSIFGDIALEISSNEARRGIEAESDEELD
                     LATPDDVSYLLYTSGTTGTPKGCVLTHRGLSEAVWALSAVCAEVDMEEGHMGNYLSIAS
                     VAFDVHLAEIFIPLARGMSIVSAPRSTLLEDLPYFIKELKISHLGIVPSLIEATMGSIQ
                     EDVESGGSTTLRYIASGGEKMSDAILDKWANHPTVRLANFYGPSEVTIGCAARFMDKTT
                     PRANIGHPFASVSAFVVDENMNILLRGAPGELVVEGPLVGVGYHGRPDLTEKVFLEFPE
                     RGAGRWAYRTGDLVRMMPDGTLEVIGRIDTQIKLRGVRIESEGISSIVRSAGLPEHTLD
                     VVTILGKHPAIGVEQLVSFIVWDQSTSVAVRKSTKPTVIAPSGNLLTKLSAACERELAS
                     YMRPSHFIPLNFMPLSSNGKNDAKLLTRVFQELDMDVLGSLMSRGSSTSVGSPNSGRTQ
                     LTKAEGQLLEIAKKHVHVPSGAANPNTNLFRYGLDSMSAVRLAAELRRTFSKVITASDI
                     LKSPSLEQIAKALDASSSSDQEQSPVESFVQRFSAERMQDVTEAYDSHVISAIYPPFPL
                     QEGILYRSVNADTLYVQHVLLELAPGVSVDKLRQAWIDVVISSPILRTVFHFGRDLVQV
                     VLHSDDVSRDIGEDVVHCDDAEAFKALFAERQSSVASKINQNVADTSPHRFTIYRSKDN
                     GLVFVGLSIHHALFDGISLSHILRNLEKVYLDEPGYPSAAPEAVLDTIASVNVQTAQDF
                     WVQHFAGFDWNRMPSRTASAKRADEKSLTFQIGLSELQRKASERRITLQSLLMTAFAHF
                     LAKYMYGHNDVAFGIIRSGRSLPIADIETTVLPLLSVLPARVVLSASDVLRNVQTFNAE
                     VTAYEHIPLGKIQQWVRPGANLFETLFSLSYKDDGRSSVWRLLESHNPEPDYILAVEVV
                     LDTTEDRLTVQVAYTSQDLSSDIVDHLLDNFEGLALDLAQGSALNVETDSAAESGTALT
                     SSEQTTQVTDIDAGEIDAVDEDLLLRLRKIVANFLQISVDLVTEGVSLVALGLDSIRSV
                     GLSRVLRKEGIELASAEIMKLATPRRMAASAGKKISIPSTTKHKIDAYASSFARERDRI
                     RAALDAASVSLSPDDEVDVFPVTTLQAGMLSQTVSSAGRRYVHLFPLRLTNGVDVAKLR
                     DAWAKTVDALGILRTTFHFVPDLGIWTSAVHSKSPLKWSEIYLLEDASLLPLLDAVTIT
                     DAGCNSPPYQLYLVRSQEVDSQEDCRLIMVLHHALYDGVSISKLLDIVGASYNGEVTQN
                     IVQFTSLLPEILWQEHLGTSFWVERLKNFHHGLVVPRLPDGSHSKKSHVASSVLNVSRS
                     EVEKVCRLTAVTTQCVGQYAFAKLLASLTRSTDILFGHVVSGRNVSGAEDVIGPVLNTV
                     PCRVRFASSVSNKLLLQAIHDTNVTALSWQHASLRSIQSHLKVERLWDCLFVFQPSQAT
                     ETSEHKSVWEFDEVEDEDIDIQYGFNLELHETAAGFLLKAACSDRLMDAEDLGAALERF
                     GLFLRVLVDDLDASCLNGLPDLTAPTTPHSVSESDFETDQIVSSWDEKSSTLRELLSTA
                     TGIPSSKIQMSMRLLGLGIDSISAIQIASKARRTGLHLTARDIIQSRTVGDLVMRAGAE
                     DESEDRAGQALQTAFQIPRQEWSALTPKVKESDVDSVTVATPGMQWFMGGWQRSGGSRY
                     QHVFGFELSADVDILKLQKAWDELLTRHAILRAAFSSSAQGEPRVVIYKRESMGARWQE
                     EECDDIQDYDEGVASRMRALISSPPSSMQEPLTRATLLRSPSRNALIIHLHHFQYDAWS
                     LQLLLDDLVRLYQGQPPTSSNDHSAILRVAVPDEHTRTEQRSYWQRMLTPNDPTLILFP
                     KIPGHQARSNSSHNFLMKKSVLTPIADLEARARALSVSLYVVYLTCWAQVQAAATSSNS
                     AIFGLWHSGRTGSIDQVECLAAPCLNILPFVVRGFNSTSTMDIATQIQDDLRERTPLVE
                     QSPLTLVDEVMGGTGRPLCNVFVNIVRAAPELHSTQQTIFTPIDVPYFIPEAPSRGKTA
                     MPELKVTGLIQDDIIVDIVDVSERGEVAMSIEFSEDTLDVETAEAMILQWVQLVKECLA
                     "
     CDS_motif       202..246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0001"
                     /evalue="1.40E+01"
                     /label="Cy4"
                     /locus_tag="NPS2"
                     /protein_end="82"
                     /protein_start="67"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="AVLVATIGRVLGAYC"
     aSDomain        join(805..1020,1138..1357,1419..1550,1606..1856,1909..1961,
                     2013..2346)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_AMP-binding.1"
                     /evalue="3.30E-94"
                     /label="NPS2_AMP-binding.1"
                     /locus_tag="NPS2"
                     /protein_end="670"
                     /protein_start="268"
                     /score="307.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="WYGALADDHHPGTSQPETMTFGEWHRRANQMARWLVARGLEKGDK
                     VAVCMKRDTSYHVSLIAVLKAGACYVPIDPELPSERQSYIACDSGARFVLVSSETASTS
                     IFGDIALEISSNEARRGIEAESDEELDLATPDDVSYLLYTSGTTGTPKGCVLTHRGLSE
                     AVWALSAVCAEVDMEEGHMGNYLSIASVAFDVHLAEIFIPLARGMSIVSAPRSTLLEDL
                     PYFIKELKISHLGIVPSLIEATMGSIQEDVESGGSTTLRYIASGGEKMSDAILDKWANH
                     PTVRLANFYGPSEVTIGCAARFMDKTTPRANIGHPFASVSAFVVDENMNILLRGAPGEL
                     VVEGPLVGVGYHGRPDLTEKVFLEFPERGAGRWAYRTGDLVRMMPDGTLEVIGRIDTQI
                     KLR"
     aSModule        805..2985
                     /complete
                     /domains="nrpspksdomains_NPS2_AMP-binding.1"
                     /domains="nrpspksdomains_NPS2_PP-binding.1"
                     /locus_tags="NPS2"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       join(988..1020,1138..1143)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0002"
                     /evalue="4.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="NPS2"
                     /protein_end="342"
                     /protein_start="329"
                     /score="16.8"
                     /tool="antismash"
                     /translation="AVLKAGACYVPID"
     CDS_motif       join(1336..1357,1419..1456)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0003"
                     /evalue="2.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="NPS2"
                     /protein_end="426"
                     /protein_start="406"
                     /score="26.0"
                     /tool="antismash"
                     /translation="SYLLYTSGTTGTPKGCVLTH"
     CDS_motif       2143..2226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0004"
                     /evalue="6.50E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="NPS2"
                     /protein_end="630"
                     /protein_start="602"
                     /score="34.5"
                     /tool="antismash"
                     /translation="GAPGELVVEGPLVGVGYHGRPDLTEKVF"
     CDS_motif       2314..2361
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0005"
                     /evalue="6.80E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="NPS2"
                     /protein_end="675"
                     /protein_start="659"
                     /score="18.7"
                     /tool="antismash"
                     /translation="IGRIDTQIKLRGVRIE"
     CDS_motif       2743..2790
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0006"
                     /evalue="1.10E-01"
                     /label="C5_LCL_267-296"
                     /locus_tag="NPS2"
                     /protein_end="818"
                     /protein_start="802"
                     /score="5.1"
                     /tool="antismash"
                     /translation="VGSPNSGRTQLTKAEG"
     aSDomain        2791..2985
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_PP-binding.1"
                     /evalue="3.30E-13"
                     /label="NPS2_PP-binding.1"
                     /locus_tag="NPS2"
                     /protein_end="883"
                     /protein_start="818"
                     /score="41.9"
                     /tool="antismash"
                     /translation="QLLEIAKKHVHVPSGAANPNTNLFRYGLDSMSAVRLAAELRRTFS
                     KVITASDILKSPSLEQIAKA"
     aSDomain        join(3103..3266,3325..3934,3989..4075)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.20E-35"
                     /label="NPS2_Condensation_DCL.1"
                     /locus_tag="NPS2"
                     /protein_end="1209"
                     /protein_start="922"
                     /score="112.6"
                     /tool="antismash"
                     /translation="AIYPPFPLQEGILYRSVNADTLYVQHVLLELAPGVSVDKLRQAWI
                     DVVISSPILRTVFHFGRDLVQVVLHSDDVSRDIGEDVVHCDDAEAFKALFAERQSSVAS
                     KINQNVADTSPHRFTIYRSKDNGLVFVGLSIHHALFDGISLSHILRNLEKVYLDEPGYP
                     SAAPEAVLDTIASVNVQTAQDFWVQHFAGFDWNRMPSRTASAKRADEKSLTFQIGLSEL
                     QRKASERRITLQSLLMTAFAHFLAKYMYGHNDVAFGIIRSGRSLPIADIETTVLPLLSV
                     LPARVV"
     aSModule        3103..4797
                     /domains="nrpspksdomains_NPS2_Condensation_DCL.1"
                     /domains="nrpspksdomains_NPS2_PP-binding.2"
                     /incomplete
                     /locus_tags="NPS2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       join(3166..3266,3325..3337)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0007"
                     /evalue="1.60E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="NPS2"
                     /protein_end="981"
                     /protein_start="943"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LYVQHVLLELAPGVSVDKLRQAWIDVVISSPILRTVFH"
     CDS_motif       3563..3628
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0008"
                     /evalue="2.30E-03"
                     /label="C3_DCL_135-156"
                     /locus_tag="NPS2"
                     /protein_end="1078"
                     /protein_start="1056"
                     /score="10.7"
                     /tool="antismash"
                     /translation="IHHALFDGISLSHILRNLEKVY"
     CDS_motif       3848..3898
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0009"
                     /evalue="2.70E-03"
                     /label="Cy4"
                     /locus_tag="NPS2"
                     /protein_end="1168"
                     /protein_start="1151"
                     /score="10.9"
                     /tool="antismash"
                     /translation="RITLQSLLMTAFAHFLA"
     CDS_motif       join(3920..3934,3989..4063)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0010"
                     /evalue="1.30E-04"
                     /label="C5_DCL_263-294"
                     /locus_tag="NPS2"
                     /protein_end="1205"
                     /protein_start="1175"
                     /score="14.4"
                     /tool="antismash"
                     /translation="DVAFGIIRSGRSLPIADIETTVLPLLSVLP"
     CDS_motif       4118..4204
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0011"
                     /evalue="1.90E-05"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="NPS2"
                     /protein_end="1252"
                     /protein_start="1223"
                     /score="16.9"
                     /tool="antismash"
                     /translation="AEVTAYEHIPLGKIQQWVRPGANLFETLF"
     aSDomain        4609..4797
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_PP-binding.2"
                     /evalue="5.90E-09"
                     /label="NPS2_PP-binding.2"
                     /locus_tag="NPS2"
                     /protein_end="1431"
                     /protein_start="1368"
                     /score="28.3"
                     /tool="antismash"
                     /translation="RLRKIVANFLQISVDLVTEGVSLVALGLDSIRSVGLSRVLRKEGI
                     ELASAEIMKLATPRRMAA"
     aSDomain        join(4939..4983,5035..5814,5868..5894)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_Condensation_DCL.2"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.50E-36"
                     /label="NPS2_Condensation_DCL.2"
                     /locus_tag="NPS2"
                     /protein_end="1762"
                     /protein_start="1478"
                     /score="116.7"
                     /tool="antismash"
                     /translation="DVFPVTTLQAGMLSQTVSSAGRRYVHLFPLRLTNGVDVAKLRDAW
                     AKTVDALGILRTTFHFVPDLGIWTSAVHSKSPLKWSEIYLLEDASLLPLLDAVTITDAG
                     CNSPPYQLYLVRSQEVDSQEDCRLIMVLHHALYDGVSISKLLDIVGASYNGEVTQNIVQ
                     FTSLLPEILWQEHLGTSFWVERLKNFHHGLVVPRLPDGSHSKKSHVASSVLNVSRSEVE
                     KVCRLTAVTTQCVGQYAFAKLLASLTRSTDILFGHVVSGRNVSGAEDVIGPVLNTVPCR
                     VRF"
     aSModule        4939..6623
                     /domains="nrpspksdomains_NPS2_Condensation_DCL.2"
                     /domains="nrpspksdomains_NPS2_PP-binding.3"
                     /incomplete
                     /locus_tags="NPS2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5077..5169
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0012"
                     /evalue="1.70E-04"
                     /label="C2_DCL_024-062"
                     /locus_tag="NPS2"
                     /protein_end="1538"
                     /protein_start="1507"
                     /score="13.9"
                     /tool="antismash"
                     /translation="LRLTNGVDVAKLRDAWAKTVDALGILRTTFH"
     CDS_motif       5371..5427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0013"
                     /evalue="3.10E-02"
                     /label="NRPS-E2"
                     /locus_tag="NPS2"
                     /protein_end="1624"
                     /protein_start="1605"
                     /score="7.2"
                     /tool="antismash"
                     /translation="LIMVLHHALYDGVSISKLL"
     CDS_motif       join(5743..5814,5868..5885)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0014"
                     /evalue="4.50E-11"
                     /label="C5_DCL_263-294"
                     /locus_tag="NPS2"
                     /protein_end="1759"
                     /protein_start="1729"
                     /score="35.2"
                     /tool="antismash"
                     /translation="DILFGHVVSGRNVSGAEDVIGPVLNTVPCR"
     CDS_motif       5955..6035
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0015"
                     /evalue="7.80E-01"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="NPS2"
                     /protein_end="1809"
                     /protein_start="1782"
                     /score="2.1"
                     /tool="antismash"
                     /translation="LSWQHASLRSIQSHLKVERLWDCLFVF"
     aSDomain        6438..6623
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_PP-binding.3"
                     /evalue="1.70E-09"
                     /label="NPS2_PP-binding.3"
                     /locus_tag="NPS2"
                     /protein_end="1986"
                     /protein_start="1924"
                     /score="30.0"
                     /tool="antismash"
                     /translation="TLRELLSTATGIPSSKIQMSMRLLGLGIDSISAIQIASKARRTGL
                     HLTARDIIQSRTVGDLV"
     aSDomain        6807..7625
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NPS2_Condensation_DCL.3"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.00E-34"
                     /label="NPS2_Condensation_DCL.3"
                     /locus_tag="NPS2"
                     /protein_end="2320"
                     /protein_start="2047"
                     /score="109.3"
                     /tool="antismash"
                     /translation="GSRYQHVFGFELSADVDILKLQKAWDELLTRHAILRAAFSSSAQG
                     EPRVVIYKRESMGARWQEEECDDIQDYDEGVASRMRALISSPPSSMQEPLTRATLLRSP
                     SRNALIIHLHHFQYDAWSLQLLLDDLVRLYQGQPPTSSNDHSAILRVAVPDEHTRTEQR
                     SYWQRMLTPNDPTLILFPKIPGHQARSNSSHNFLMKKSVLTPIADLEARARALSVSLYV
                     VYLTCWAQVQAAATSSNSAIFGLWHSGRTGSIDQVECLAAPCLNILPFVVR"
     CDS_motif       6831..6923
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0016"
                     /evalue="1.90E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="NPS2"
                     /protein_end="2086"
                     /protein_start="2055"
                     /score="26.6"
                     /tool="antismash"
                     /translation="GFELSADVDILKLQKAWDELLTRHAILRAAF"
     CDS_motif       7143..7208
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0017"
                     /evalue="4.50E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="NPS2"
                     /protein_end="2181"
                     /protein_start="2159"
                     /score="16.1"
                     /tool="antismash"
                     /translation="LHHFQYDAWSLQLLLDDLVRLY"
     CDS_motif       7530..7616
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NPS2_0018"
                     /evalue="2.00E-02"
                     /label="C5_DCL_263-294"
                     /locus_tag="NPS2"
                     /protein_end="2317"
                     /protein_start="2288"
                     /score="7.5"
                     /tool="antismash"
                     /translation="IFGLWHSGRTGSIDQVECLAAPCLNILPF"
ORIGIN
        1 atgagcgcac acacccggac agactgcgat caccctgagc ttcccaagct cgccacggtc
       61 atctcaggat ataggcactg cgacctgcca gatttatcct cagatcgctt ccctgccagc
      121 accacgtact ccgtctctgc ctgtatcaag gaatcgctga taagcactca ggtcgatgtg
      181 ctcgacgcgc gagccccctt cgccgtgctc gttgcaacaa tcggacgagt tctgggagct
      241 tactgcggat gtaccgacgt tattctcgca cttacggatc aggactgtga agacctccgc
      301 actgccagaa ttacttggga cgaaaataca caatgggcag atctcctcca taccgttctc
      361 cagagtctca gcggcgacac ttcattccgc attaccgtcc ccgccatccg cgaagctctt
      421 ggactcactg aaaagcaggc gccctgccta gcccttgtcc gagatgcacc gtcttcagat
      481 tacgacaaca cagacttccc tctcgtattc aactgggata tttcgacttt tacactccgt
      541 ctattcactt ccgagcgcca tctccaccct tctggtgccg atctgttggc atcgcagatc
      601 gcatctctcc tcgtgccggc gcttacgaat ccagcaactc aggtattccg ccttccagac
      661 ttgcaagcag atctgctatc aatctacgag aagttgacct tcgaagatcg ctgtcaggcg
      721 tactctcgtg tgccgcctgt gcgcctcgca acagaccacc tcactctcag actcgcaagc
      781 caggcaaacg acgttgccgt ggaatggtat ggcgctctcg cagatgatca tcaccccggg
      841 acgtcacaac cggaaacgat gacctttggc gagtggcatc ggagggcgaa tcaaatggcc
      901 cgctggcttg tcgcacgtgg cctcgaaaaa ggtgataagg tggcagtgtg catgaagcgc
      961 gacacaagtt accatgtttc gctcatcgct gtcctcaagg ctggagcatg ttatgtgccg
     1021 gtgagtcttt cgcgtggtta tctttcactt ttgtcaatca gctgcgttat cggcggcgct
     1081 tctcgacatt ccttcggcaa tcgaatttga ttttccacgt tgctgacgac tatctagatc
     1141 gatcctgagc tcccatccga gaggcagagt tacattgcct gcgactctgg tgctcgcttc
     1201 gtgctagtct cctctgagac ggcctctacc tcaatctttg gcgacattgc tctcgaaatt
     1261 tcgagtaatg aagcgcggcg tggtatcgag gcagagagcg acgaagagct cgatctcgca
     1321 actcctgatg atgtctccta cctgctctac acctctggtg ggtcctcatc gtcacgttcg
     1381 gcctgactta ccatgcttaa tgtctttcgc tttcgcaggg acaaccggta ctccgaaggg
     1441 atgcgtcctg acccatcggg gcctgagtga agcagtatgg gccctgagcg ctgtctgcgc
     1501 tgaagtagat atggaagagg gacatatggg caattatctg tcaatcgcct gtgagatcgt
     1561 gtatcttcat tcatgtatcg atatgtactc aatatatatc ttcagcggtc gccttcgatg
     1621 tacacttggc ggagatcttc atcccccttg cgcgtgggat gtcgatcgtg tctgcacccc
     1681 ggtcgacgct gttggaagac ctaccatatt tcataaagga actcaagatc tcacatctcg
     1741 gaatcgtccc ttcgctgatc gaggcgacta tgggttcgat acaagaggac gtagagagtg
     1801 gtggcagtac cacattgcgc tacatcgcta gtggtggcga gaaaatgagc gatgcagtca
     1861 gtgttctttc ggaattacac gtgaacaagc tcgctgaact ttggtcagat cttggataaa
     1921 tgggccaatc atccgacggt caggctagcc aacttctatg ggtatgttgt cctatacgtg
     1981 tctttgatct caattgatgc gcattcttct agtccgagcg aagtcactat aggttgtgcc
     2041 gctcgcttca tggacaagac aactccccgt gccaacatcg gtcatccgtt cgctagcgtc
     2101 tctgccttcg tcgtcgacga gaatatgaac atcctccttc gcggtgctcc tggagaactc
     2161 gtcgtagaag gtccactggt tggagtggga taccatggtc gtcccgatct cacggagaag
     2221 gtgttcctgg agttcccaga gcgcggcgcc ggccgttggg cataccgaac tggcgatctc
     2281 gttcgcatga tgcccgatgg tacgctagaa gtgattggcc gtatcgatac gcagatcaag
     2341 ctccgcgggg tgcgcatcga gtccgagggc atttcgtcca tcgtccgcag tgcaggactt
     2401 ccggagcaca ccctggacgt ggtcaccatc ctcggaaagc accctgccat cggagtcgag
     2461 cagctggttt cattcattgt atgggaccag tcgacaagcg tagccgtgcg gaagtcgacg
     2521 aagcctacag tgatcgcgcc gtcggggaac ttgctgacaa agctcagtgc ggcttgcgaa
     2581 cgtgagctgg cgagctacat gcgcccaagc cacttcatcc cgctgaactt catgcccttg
     2641 agctcgaacg gcaagaatga tgccaaactc cttacgcgcg tcttccagga actcgacatg
     2701 gacgtgctcg gatcgttgat gtctcgaggt agctcgacca gcgtcggttc tcccaactcc
     2761 ggaaggacac aactgacaaa ggccgaggga cagctcctcg agatcgccaa gaagcatgtt
     2821 catgtcccct ctggagcagc aaatccgaat accaatctat tccgttatgg tctcgactcg
     2881 atgtctgcag tacggcttgc tgcggagctg aggcgcactt tcagcaaagt catcactgct
     2941 tccgatattt tgaaatcccc atcccttgag cagattgcga aggccttaga tgcgtcatct
     3001 tcctccgatc aagagcaatc accggtagaa tctttcgttc aacgcttctc tgctgagcga
     3061 atgcaggatg tcaccgaggc atatgactcg catgtcatct cagctatcta ccctccattt
     3121 ccgctgcaag agggaatcct atatcgctcc gtgaatgcag acacactcta tgttcagcac
     3181 gttctcttag agctggctcc gggcgtctct gttgacaaac tacgccaagc atggatagac
     3241 gtagtgatat cttctcccat tcttcggttg gtactcttat acatctttca cgcgtatgaa
     3301 gactgatcaa atgtctccgt tcagtactgt gttccatttc ggtcgggact tggtccaggt
     3361 ggtgctgcac tcggatgacg tgtcacgtga tatcggcgaa gacgtcgtgc actgcgacga
     3421 tgccgaggca tttaaggcac tcttcgcaga aaggcagtca tcagtagctt cgaaaatcaa
     3481 ccaaaatgtc gccgatacct ctccgcaccg gttcacgata tatcgatcta aggacaacgg
     3541 gcttgttttc gtgggcttat ctatacacca tgcgctattc gacggcattt ctctctccca
     3601 catcctacgc aatctggaaa aggtctatct tgatgaacct ggatacccgt cggcagctcc
     3661 tgaagctgtg cttgatacta ttgcatctgt taacgttcaa actgcgcagg acttttgggt
     3721 gcaacacttc gcgggtttcg actggaatcg catgccctct cgtaccgctt ctgcgaagcg
     3781 cgcagacgag aagtctctga cgttccaaat agggctgtcc gagttacaga gaaaagcatc
     3841 ggaacgtcga atcacgctgc agagtttgct tatgacagct tttgcccact ttctggcgaa
     3901 atatatgtac ggacataacg atgtcgcttt cggagtatgt acaatgatgc tgaaccagac
     3961 gtgagactaa ctaatacttc attttcagat cattcgctcc ggaaggtcgc ttcctatcgc
     4021 ggatatcgag acaacagtgc tcccgctact ctcggtcctt ccggcgcgcg ttgttttgtc
     4081 tgcctcggac gtgttgcgca acgttcaaac tttcaacgca gaggtgactg catacgagca
     4141 catccccctg ggcaagattc agcaatgggt tagacctggt gccaatctat tcgaaactct
     4201 gttctcgtta tcctataaag atgatggtcg gagctctgtg tggcgcttac tagagagcca
     4261 taatcctgag cctgatgtac gtactcactt tgttggctcc acgcatatgg tggttcctga
     4321 cgaccgaaac agtacattct tgcagtcgag gttgtcttag acaccacaga ggaccgcctg
     4381 acggtacaag tcgcatacac ctcgcaggac ctgtcctccg acatcgttga ccaccttctt
     4441 gacaatttcg aaggcttagc actggatctc gcgcagggta gcgcgttaaa cgtggagaca
     4501 gactcagccg cagaatccgg taccgctttg acgtcaagcg agcagacgac tcaggttacc
     4561 gatattgacg ccggagaaat cgacgctgtt gacgaagatc tactcctacg ccttcgtaag
     4621 attgtggcaa atttcctcca gatcagtgtc gacctggtca cggaaggggt gtcgctcgtc
     4681 gctctgggac tggattccat ccgatcagtc ggcttgagcc gcgtacttcg aaaggagggc
     4741 attgaactcg cgtcggcgga gattatgaag ctcgcaactc ctcgtcgaat ggctgcatcg
     4801 gccggcaaga agatctcaat accgtcgacc actaaacaca agattgacgc gtatgcctcg
     4861 tcatttgcga gagaacgtga caggatacga gcagccttgg atgctgcgtc agtctccctg
     4921 tctcccgacg atgaagtaga cgtctttcca gtaaccacac tgcaagcggg catgctttcc
     4981 caagtaagcc atctacatgc gggcatcgtg ttttagtact gactttgcga ctagacagtc
     5041 agctctgccg ggaggcgtta cgtgcacctg ttcccgctcc gccttacaaa cggtgtggat
     5101 gtcgccaaac tccgagatgc gtgggcgaag actgtcgatg cgcttggcat attgcgcact
     5161 acgttccact tcgtacctga tcttgggata tggacctcgg cagtgcactc gaagagccca
     5221 ttgaagtggt cagaaattta tctactcgaa gacgccagcc tactgcctct actggacgcg
     5281 gtcacaatca ctgacgcggg atgcaactca ccgccttacc agctgtatct ggtacgttcg
     5341 caagaggtgg attctcagga ggactgtcgc ctcataatgg tcctgcatca tgctttatac
     5401 gatggtgttt ctatttccaa actgttggac atcgtcggag caagctacaa cggggaggtc
     5461 acccagaaca tcgtccagtt tacttcgctt cttcccgaga tcttgtggca ggagcaccta
     5521 ggaacgtcat tctgggttga acgtctgaag aacttccatc acggactagt ggtccctagg
     5581 ctaccagacg gaagccactc aaagaagtct catgtcgcct catcagttct gaacgtaagc
     5641 aggagcgaag tggagaaagt gtgccgtctt actgctgtca ctacgcaatg cgtcggacaa
     5701 tacgcattcg ccaagctcct tgcgtcgttg accaggtcga cggacatcct gtttgggcac
     5761 gttgtgtcag ggaggaacgt atctggagcg gaagatgtca ttgggccggt tttagtaagt
     5821 ggtcagcttg ccacatgtct cctgttcttg ctaacgagtg atggcagaac actgtccctt
     5881 gccgtgtcag attcgcgagt tctgtttcca ataagctcct cctgcaagcc attcacgata
     5941 ctaatgtaac cgccctgtct tggcaacatg cgtctcttcg atctatccaa tctcatctga
     6001 aagtagagcg gctgtgggac tgtctgttcg tcttccagcc ttcgcaggct acggaaactt
     6061 ccgaacataa gtcagtttgg gagttcgacg aagtagaaga cgaggatatt gatatacagg
     6121 tgagtgttgc atccccccaa aacgtctgaa gcctgacaag tatcgacttg gtatagtacg
     6181 gcttcaatct ggaattgcat gagacagctg ccgggtttct gctcaaagca gcctgctcag
     6241 accgcttgat ggatgctgaa gatcttggcg ctgcgctcga gcgtttcggg ctattcctac
     6301 gggttttggt agatgatctg gacgcgtctt gcttgaatgg actcccagac ctcacagctc
     6361 cgacgacacc acactcggtc tcggagtcgg acttcgaaac agatcagatt gtttccagct
     6421 gggacgagaa gtcatctact ttgcgcgaat tactttctac agcgactggg attccatcat
     6481 cgaaaatcca gatgtcaatg cgcttgcttg gtcttgggat cgactcaatc agtgccatcc
     6541 agattgcgtc taaggcgcgt agaactggac tccatctgac cgcccgtgat atcatccaat
     6601 ctcggaccgt cggtgacctg gtcatgcgcg ctggggcaga agatgaaagt gaagaccgtg
     6661 cggggcaagc cttgcaaacc gcttttcaga ttccacggca agaatggtct gccctgacac
     6721 caaaggtcaa agaatcggac gtagatagcg ttacggtggc tacaccaggg atgcagtggt
     6781 tcatgggagg atggcagcgc agtggaggct ctcggtacca acacgttttt ggctttgagc
     6841 tttcggcgga cgtcgacata ttgaagttac aaaaagcttg ggacgagctg ttgacgaggc
     6901 atgccatact tcgtgccgct ttttcgtctt cagcgcaagg agaaccacgc gtggtcatct
     6961 acaaacggga gtctatgggc gcacgatggc aggaagaaga atgcgatgat atccaggatt
     7021 acgatgaagg ggttgcgtcg agaatgcgag cgttgatctc ttctccgccc tcaagcatgc
     7081 aagagccgct gacaagggcc accctattac gctctccgtc acggaacgcg ttgattatac
     7141 acctacatca ctttcaatac gatgcgtgga gtctccagct cttgcttgac gacctcgtcc
     7201 ggctttatca aggtcagccg ccaacaagct cgaatgacca ttcggccatt ctgcgtgtcg
     7261 ctgtaccaga cgagcatact cgaacagagc aacggtcata ctggcagagg atgcttaccc
     7321 caaatgaccc tacgttgatt ttgttcccga aaataccagg tcatcaggcc cgatccaaca
     7381 gcagtcacaa cttcttgatg aagaagagcg tcctcacacc aatcgcagac ctcgaagcac
     7441 gcgctcgcgc tctatcagta tccctgtacg tcgtgtactt gacttgctgg gcacaagtac
     7501 aggcagcagc aacttcaagc aattccgcta tcttcggttt atggcactca ggacgcacgg
     7561 gttccattga ccaagtcgag tgtctcgcag cgccttgtct caacatactg ccattcgtcg
     7621 tacgcggttt caacagcacc agtaccatgg acatcgctac tcaaatccag gacgatctgc
     7681 gggagcgaac cccgctcgtc gagcaatctc ccttaaccct ggtggatgag gtaatgggag
     7741 gaacgggtcg accgctttgc aatgtcttcg tgaacattgt cagagctgct cccgaattac
     7801 acagcacaca gcagacaata tttacaccca tcgatgtgag tctcttccat tgcaggaaag
     7861 cgttcagaat gggttgacct ggctacatag gtgccttact ttatccccga agcgccctcg
     7921 agaggtaaga ctgcaatgcc tgagttgaaa gtgacaggcc tcatccaagt acgtcgttaa
     7981 ttttatgtcc gcttcgagtt cagctgatcg atcgattatt taggatgata tcatcgtcga
     8041 tattgtcgat gtgtcagagc gcggcgaagt tgcgatgtct atcgaattct cggaggatac
     8101 actcgacgtg gaaacagcgg aggcaatgat attacagtgg gttcagctag tcaaggagtg
     8161 ccttgcttag
//
