BGC0001533: borrelidin biosynthetic gene cluster from Streptomyces rochei
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 63,657 nt. (total: 63,657 nt).
This entry is originally from NCBI GenBank KT362046.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001533
Short description borrelidin biosynthetic gene cluster from Streptomyces rochei
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KT362046.1
Compounds
  • borrelidin
Species Streptomyces rochei [taxonomy]
References
Chemical products information
borrelidin
Copy SMILES
C28H43N1O6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ALV82340.1
26 - 313 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82324.1
501 - 3107 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82339.1
3162 - 3800 (-) diguanylate cyclase
copy AA seq
copy Nt seq
  • ALV82316.1
3925 - 4893 (-) AraC family transcriptional regulator
copy AA seq
copy Nt seq
  • ALV82327.1
5113 - 5943 (+) chloroperoxidase
copy AA seq
copy Nt seq
  • ALV82332.1
5951 - 6457 (-) putative decarboxylase
copy AA seq
copy Nt seq
  • ALV82329.1
6554 - 7528 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82314.1
  • bor2B
7593 - 8387 (-) thioesterase
copy AA seq
copy Nt seq
  • ALV82322.1
  • bor2C
8387 - 9184 (-) ketoreductase
copy AA seq
copy Nt seq
  • ALV82326.1
  • bor2D
9234 - 9986 (-) putative reductase
copy AA seq
copy Nt seq
  • ALV82328.1
  • bor2E
9983 - 11155 (-) putative muconate cyclo-isomerase/lactamase
copy AA seq
copy Nt seq
  • ALV82333.1
  • bor2F
11152 - 11970 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82334.1
  • bor2G
11982 - 13601 (-) putative acetolactate synthase
copy AA seq
copy Nt seq
  • ALV82343.1
  • bor2H
13598 - 15625 (-) putative dehydratase
copy AA seq
copy Nt seq
  • ALV82318.1
  • bor2A1
16288 - 18804 (+) borrelidin type I polyketide synthase
copy AA seq
copy Nt seq
  • ALV82346.1
  • bor2A2
18865 - 23586 (+) borrelidin type I polyketide synthase
copy AA seq
copy Nt seq
  • ALV82320.1
  • bor2A3
23682 - 34184 (+) borrelidin type I polyketide synthase
copy AA seq
copy Nt seq
  • ALV82341.1
  • bor2A4
34181 - 39043 (+) borrelidin type I polyketide synthase
copy AA seq
copy Nt seq
  • ALV82345.1
  • bor2A5
39118 - 45510 (+) borrelidin type I polyketide synthase
copy AA seq
copy Nt seq
  • ALV82335.1
  • bor2A6
45510 - 50738 (+) borrelidin type I polyketide synthase
copy AA seq
copy Nt seq
  • ALV82330.1
  • bor2I
50825 - 52015 (+) putative cytochrome P450
copy AA seq
copy Nt seq
  • ALV82319.1
  • bor2J
52109 - 53473 (+) putative aminotransferase
copy AA seq
copy Nt seq
  • ALV82323.1
  • bor2K
53482 - 54462 (+) putative oxidoreductase
copy AA seq
copy Nt seq
  • ALV82337.1
  • bor2L
54502 - 56172 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82315.1
  • bor2M
56177 - 57094 (+) putative dehydrogenase
copy AA seq
copy Nt seq
  • ALV82347.1
  • bor2N
57108 - 57854 (+) putative 2-hydroxyhept-2,4-diene-1,7-dioate isomerase
copy AA seq
copy Nt seq
  • ALV82331.1
  • bor2O
57935 - 59962 (+) threonyl-tRNA synthetase
copy AA seq
copy Nt seq
  • ALV82344.1
60149 - 60508 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82338.1
60616 - 60999 (+) anti-sigma factor antagonist
copy AA seq
copy Nt seq
  • ALV82342.1
61184 - 61432 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82317.1
61522 - 61734 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ALV82325.1
61763 - 62224 (-) putative regulatory protein
copy AA seq
copy Nt seq
  • ALV82336.1
62582 - 63064 (-) acetyltransferase
copy AA seq
copy Nt seq
  • ALV82321.1
63152 - 63655 (-) hypothetical protein
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.