BGC0001533: borrelidin biosynthetic gene cluster from Streptomyces rochei
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Location: 1 - 63,657 nt. (total: 63,657 nt).
This entry is originally from NCBI GenBank KT362046.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001533
Short description borrelidin biosynthetic gene cluster from Streptomyces rochei
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KT362046.1
via
Compounds
  • borrelidin
Species Streptomyces rochei [taxonomy]
References
Chemical products information
borrelidin Evidence:
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C28H43N1O6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ALV82340.1
 26 - 313 (+) hypothetical protein
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    • ALV82324.1
    		 501 - 3107 (+) hypothetical protein
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      • ALV82339.1
      		 3162 - 3800 (-) diguanylate cyclase
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        • ALV82316.1
        		 3925 - 4893 (-) AraC family transcriptional regulator
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          • ALV82327.1
          		 5113 - 5943 (+) chloroperoxidase
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            • ALV82332.1
            		 5951 - 6457 (-) putative decarboxylase
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              • ALV82329.1
              		 6554 - 7528 (+) hypothetical protein
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                • ALV82314.1
                • bor2B
                		 7593 - 8387 (-) thioesterase
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                  • ALV82322.1
                  • bor2C
                  		 8387 - 9184 (-) ketoreductase
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                    • ALV82326.1
                    • bor2D
                    		 9234 - 9986 (-) putative reductase
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                      • ALV82328.1
                      • bor2E
                      		 9983 - 11155 (-) putative muconate cyclo-isomerase/lactamase
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                        • ALV82333.1
                        • bor2F
                        		 11152 - 11970 (-) hypothetical protein
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                          • ALV82334.1
                          • bor2G
                          		 11982 - 13601 (-) putative acetolactate synthase
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                            • ALV82343.1
                            • bor2H
                            		 13598 - 15625 (-) putative dehydratase
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                              • ALV82318.1
                              • bor2A1
                              		 16288 - 18804 (+) borrelidin type I polyketide synthase
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                                • ALV82346.1
                                • bor2A2
                                		 18865 - 23586 (+) borrelidin type I polyketide synthase
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                                  • ALV82320.1
                                  • bor2A3
                                  		 23682 - 34184 (+) borrelidin type I polyketide synthase
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                                    • ALV82341.1
                                    • bor2A4
                                    		 34181 - 39043 (+) borrelidin type I polyketide synthase
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                                      • ALV82345.1
                                      • bor2A5
                                      		 39118 - 45510 (+) borrelidin type I polyketide synthase
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                                        • ALV82335.1
                                        • bor2A6
                                        		 45510 - 50738 (+) borrelidin type I polyketide synthase
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                                          • ALV82330.1
                                          • bor2I
                                          		 50825 - 52015 (+) putative cytochrome P450
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                                            • ALV82319.1
                                            • bor2J
                                            		 52109 - 53473 (+) putative aminotransferase
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                                              • ALV82323.1
                                              • bor2K
                                              		 53482 - 54462 (+) putative oxidoreductase
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                                                • ALV82337.1
                                                • bor2L
                                                		 54502 - 56172 (+) hypothetical protein
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                                                  • ALV82315.1
                                                  • bor2M
                                                  		 56177 - 57094 (+) putative dehydrogenase
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                                                    • ALV82347.1
                                                    • bor2N
                                                    		 57108 - 57854 (+) putative 2-hydroxyhept-2,4-diene-1,7-dioate isomerase
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                                                      • ALV82331.1
                                                      • bor2O
                                                      		 57935 - 59962 (+) threonyl-tRNA synthetase
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                                                        • ALV82344.1
                                                        		 60149 - 60508 (-) hypothetical protein
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                                                          • ALV82338.1
                                                          		 60616 - 60999 (+) anti-sigma factor antagonist
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                                                            • ALV82342.1
                                                            		 61184 - 61432 (+) hypothetical protein
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                                                              • ALV82317.1
                                                              		 61522 - 61734 (+) hypothetical protein
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                                                                • ALV82325.1
                                                                		 61763 - 62224 (-) putative regulatory protein
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                                                                  • ALV82336.1
                                                                  		 62582 - 63064 (-) acetyltransferase
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                                                                    • ALV82321.1
                                                                    		 63152 - 63655 (-) hypothetical protein
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                                                                      Biosynthesis information
                                                                      Annotation changelog

                                                                      Entry version: 4

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2022-10-07
                                                                      Update chemical activity to schema version 2.11
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                      Entry version: 3

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2022-09-15
                                                                      Updated bioactivity data
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                      Entry version: 2

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2019-10-16
                                                                      Migrated from v1.4
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      2019-10-16
                                                                      Updated compound(s) information (NPAtlas curation)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                      Entry version: 1

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2018-08-06
                                                                      Submitted
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      Detailed domain annotation
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