LOCUS       BGC0001539              2710 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Streptomyces cattleya str. NRRL 8057 main chromosome, complete
            genome.
ACCESSION   BGC0001539
VERSION     BGC0001539
KEYWORDS    .
SOURCE      Streptomyces cattleya NRRL 8057 = DSM 46488
  ORGANISM  Streptomyces cattleya NRRL 8057 = DSM 46488
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     Annotation results relative to BLAST similarities, COG
            assignations, enzymatic function prediction (PRIAM software), TMHMM
            and SignalP predictions, and synteny conservation (Syntonizer
            software) are available in the MicroScope annotation system
            http://www.genoscope.cns.fr/agc/microscope.
            Accession number for plasmid pSCAT in this genome project:
            FQ859184.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 02:26:12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2710
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS_motif       1..72
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTESIEAYEPPMLVEVGSFAELTR"
                     /locus_tag="SCAT_0074_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       73..135
                     /prepeptide="core"
                     /locus_tag="SCAT_0074_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="9.70"
                     /molecular_weight="2687.7"
                     /monoisotopic_mass="2686.0"
                     /core_sequence="SYHWGDYHDWHHGWYGWWDD"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTESIEAYEPPMLVEVGSFAELTR"
                     /leader_location="[0:72](+)"
     protocluster    1..2710
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[210:2710]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      211..2710
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..2710
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..2710
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001539"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..2710
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..135
                     /locus_tag="SCAT_0074"
     CDS             1..135
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAT_0074"
                     /db_xref="EnsemblGenomes-Tr:CCB72812"
                     /db_xref="UniProtKB/TrEMBL:F8K1X2"
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="SCAT_0074"
                     /note="Evidence 4 : Homologs of previously reported genes
                     of unknown function"
                     /product="conserved protein of unknown function"
                     /protein_id="CCB72812.1"
                     /transl_table=11
                     /translation="MTESIEAYEPPMLVEVGSFAELTRSYHWGDYHDWHHGWYGWWDD"
     gene            211..2028
                     /gene="asnH"
                     /locus_tag="SCAT_0075"
     CDS             211..2028
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAT_0075"
                     /db_xref="EnsemblGenomes-Tr:CCB72813"
                     /db_xref="GOA:F8K1X3"
                     /db_xref="InterPro:IPR001962"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="InterPro:IPR029055"
                     /db_xref="UniProtKB/TrEMBL:F8K1X3"
                     /gene="asnH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 112.4; E-value: 3.7e-34)"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="SCAT_0075"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology"
                     /product="putative asparagine synthetase"
                     /protein_id="CCB72813.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-37, bitscore:
                     117.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVEFAVFPDHPHGAALARGLQSASGGRSIAHPSGRPWIVGHWAE
                     DAVVRASVGDRSAVVFGMTDFDERSLAAGLATVVSTDETGALTGPLAGSHHLCLSVGGE
                     VRLQGSLSGVREVYFAEHHGVTVASGSAALAARLSGRGVDEERLALRLLAPDAPWPVGD
                     ESGWAGVTTLPVGHWLRLARDGGGRVVRWWVPPEPRLPMAAAAAAVREALAEAVAVRTA
                     RGGVLSADLSGGLDSAGLCFLAADGPARLVTLHALAVDAGNDDSAWAARSAERLGAARH
                     VVVAADDGPRWFATPPCADGDLEGPVVLARTRAKAAHAVAHAAREGSRIHLTGIGGDEL
                     FTMRPALLHAMARAHPAVAVRQLRATRTLGRWSLLTTARQVWGGGDYPRWLARCAERLT
                     LTPGSSWVTGADWGVPPVMPPWATPRATATARRLLAAAAEARPAPLAPLRVQHDMIRAV
                     RAAGAAVRGLGHAVAGLQVAYEAPYLDDRVLDAALAVRLADRWALDHYKPVLAAALRGV
                     VPGELLDRRTKGDYSAELFTGLRRHRDDVLDVCAELADRGLVDGQALRAALTGLHPVTR
                     GLLPLDATLSCATWLRAVGHDTAWQGGAA"
     gene            2079..2282
                     /locus_tag="SCAT_0076"
     CDS             2079..2282
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAT_0076"
                     /db_xref="EnsemblGenomes-Tr:CCB72814"
                     /db_xref="InterPro:IPR008792"
                     /db_xref="UniProtKB/TrEMBL:F8K1X4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="SCAT_0076"
                     /note="Evidence 4 : Homologs of previously reported genes
                     of unknown function"
                     /product="conserved protein of unknown function"
                     /protein_id="CCB72814.1"
                     /sec_met_domain="PF05402 (E-value: 1e-14, bitscore: 42.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2e-20,
                     bitscore: 60.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLDERSGRYWQLNATGATVLEALLDTGDEALAAAALRERCPSAG
                     DRAERDVGRLVAMLRDAGLVVS"
     gene            2279..2710
                     /locus_tag="SCAT_0077"
     CDS             2279..2710
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SCAT_0077"
                     /db_xref="EnsemblGenomes-Tr:CCB72815"
                     /db_xref="UniProtKB/TrEMBL:F8JVW7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="SCAT_0077"
                     /note="Evidence 4 : Homologs of previously reported genes
                     of unknown function"
                     /product="conserved protein of unknown function"
                     /protein_id="CCB72815.1"
                     /sec_met_domain="PF13471 (E-value: 3.2e-30, bitscore: 92.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQVTLDERALLPWWRRAVALCAVFAARLLVRLPPGRLRRVLTR
                     VCRGARPAGAESAARAREAVVAVSLRCAGPYCLQRSVATALLCRLSGQWPDWCTGVRTE
                     PFRAHAWVEAEGVPVGEDAAGLRGFRVLLRVSASGRRAG"
ORIGIN
        1 gtgaccgaaa gcatcgaggc atacgagccc cccatgctgg tcgaggtcgg ctccttcgcc
       61 gagctgaccc gttcctacca ctggggtgac taccacgact ggcaccacgg ttggtacggc
      121 tggtgggacg actgacccag cgcccttgcg gctgcgccgg tgcggggaca ccggcgcagt
      181 ccgcctgcgc acatcggtga ggggggttgt gtgggggtgg agttcgcggt ctttccggac
      241 catccgcacg gcgcggcgct ggcgcggggg ttgcagagcg cgagcggggg gcggtcgatc
      301 gcccatccgt cgggcaggcc ctggatcgtg gggcactggg ccgaggacgc ggtggtgcgc
      361 gcgtccgtcg gtgaccggag cgccgtggtc ttcggcatga cggacttcga cgagcggtcg
      421 ctggcggcgg ggctggccac cgtggtctcc accgacgaga caggcgcgct caccggcccg
      481 ttggccggca gccaccacct gtgtctgtcg gtcggcggtg aagtgcgcct ccagggcagc
      541 ctgtcggggg tgcgcgaggt ctacttcgcc gagcaccacg gggtgacggt ggcctccggc
      601 agcgccgcgc tggccgcccg gctgtccggc cgcggggtgg acgaggaacg gctggccctg
      661 cggctgctgg cgccggacgc gccgtggccg gtcggcgacg agagcggctg ggccggggtc
      721 accacgctgc cggtcggcca ctggctgcgg ctcgcccggg acggcggcgg acgggtggtg
      781 cgctggtggg tgccgccgga gccacggctg ccgatggccg ccgccgcggc ggccgtacgg
      841 gaagcgctgg ccgaggcggt cgcggtccgc acggcacgcg gcggggtgct cagcgccgac
      901 ctgtccggcg gtctggactc ggccggcctg tgcttcctgg ccgccgacgg cccggcccgg
      961 ctggtcacgc tgcacgcgct ggcggtcgac gccggcaacg acgacagcgc gtgggcggcc
     1021 cggtccgccg aacggctcgg cgccgcgcgg cacgtggtgg tggccgccga cgacggcccc
     1081 cggtggttcg ccacgccgcc gtgcgccgac ggtgatctgg agggcccggt cgtgctggcc
     1141 cgcacccggg ccaaggccgc ccacgcggtg gcccacgcgg cgcgggaggg ctcccggatc
     1201 catctcaccg ggatcggcgg tgacgagttg ttcaccatgc gcccggcgtt gctgcacgcg
     1261 atggcgcggg cccatccggc ggtggcggta cggcagttgc gggccacccg gacgctgggc
     1321 cggtggtcgc tgctgaccac cgcgcgccag gtatggggcg gcggtgacta cccgcgctgg
     1381 ctggcgcgct gcgccgagcg gctcacgctc accccgggtt cgtcctgggt caccggtgcc
     1441 gactgggggg tgcccccggt gatgccgccg tgggcgacgc cacgggccac ggccaccgcg
     1501 cgccggttgc tggccgccgc ggccgaggcc cgtccggcac cgctggcccc gctgcgggtg
     1561 cagcacgaca tgatccgcgc ggtgcgcgcg gccggcgcgg cggtacgcgg tctcggtcac
     1621 gccgtcgccg gcctccaggt cgcctacgag gccccctacc tcgacgaccg ggtgctcgac
     1681 gcggcgctgg cggtgcggct ggccgaccgc tgggcgctgg accactacaa acccgtactg
     1741 gcggcggcgc tgcgcggcgt cgtccccggc gaactgctcg accgccgtac caagggcgac
     1801 tacagcgcgg agctcttcac cgggctgcgc cgccaccggg acgacgtgct cgacgtctgc
     1861 gcggaactgg ccgaccgggg cctggtggac ggccaggcgc tgcgcgcggc gctcaccggg
     1921 ctccatccgg tgacccgggg gctgctgccg ctcgacgcca cgttgtcctg cgccacctgg
     1981 ctgcgggcgg tcgggcacga cacggcgtgg caaggaggtg cggcgtgagt ttcacactgg
     2041 cccgtcatgt gacccgttcg gccaccgagg gaggcatggt gctgctggac gaacgcagcg
     2101 gccgttactg gcagttgaac gccaccgggg ccaccgtgct ggaggccctg ctggacaccg
     2161 gtgacgaggc gctggccgcc gccgctctgc gggagcggtg tccgagcgcg ggcgaccggg
     2221 cggagcggga cgtcgggcgg ctggtcgcca tgttgcggga cgccgggctg gtggtgtcgt
     2281 gagcgcccag gtgacgctgg acgagcgggc gttgctgccg tggtggcggc gggcggtggc
     2341 gttgtgcgcg gtcttcgcgg cccggctgct ggtgcgcctg ccgccggggc ggttgcggcg
     2401 ggtgctcacc cgggtgtgcc ggggcgcgcg gccggccggc gcggagtcgg cggcccgggc
     2461 gcgggaggcg gtggtggcgg tgagtctgcg ctgcgccggc ccctactgcc ttcaacggtc
     2521 ggtggccacc gcgttgttgt gccggctctc cggtcagtgg ccggactggt gcacgggggt
     2581 gcgcaccgag ccgttccggg cgcacgcctg ggtcgaggcg gagggtgttc cggtcggcga
     2641 ggacgcggcg gggttgcgcg gtttccgggt gctgctgagg gtctccgcct cggggaggcg
     2701 ggccgggtag
//
