LOCUS       BGC0001542             22797 bp    DNA     linear   PLN 08-JUN-2018
DEFINITION  Cercospora zeina CTB gene cluster and oxidoreductase (CTB7)
            pseudogene, partial sequence.
ACCESSION   BGC0001542
VERSION     BGC0001542
KEYWORDS    .
SOURCE      Cercospora zeina
  ORGANISM  Cercospora zeina
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Dothideomycetes; Dothideomycetidae; Mycosphaerellales;
            Mycosphaerellaceae; Cercospora.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 02:27:04
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     mRNA            complement(join(<1..169,227..761,783..1194,1246..>1329))
                     /gene="CTB8"
                     /product="zinc finger transcription factor"
     gene            complement(<1..>1329)
                     /gene="CTB8"
     CDS             complement(join(1..169,227..761,783..1194,1246..1329))
                     /codon_start=1
                     /gene="CTB8"
                     /product="zinc finger transcription factor"
                     /protein_id="ARU80376.1"
                     /transl_table=1
                     /translation="MARGGASDMPNTRDTSFKRPKIRESCTHCSSQKIRCTKERPACAR
                     CVNKGLLCQYNISRRTGTRRPSIRATPEPDTLKPMAPTSSASADSIVIHGRLSPSLSDL
                     AMLDGLDAFDDSMWAQPVVTNVEDMDMQYFDFFSAGGFEAEPEAKGLSGVDSTPLSPTE
                     VASGLSKVGMEASTRPSSSASPRSQRGGGSTGHGGGGGGCISTALQIFSELHVSGSACP
                     IAAGSADQDVRDFDHVLDSNRTALERLSSILDCRPCCRNHEVLTAAFLAIHKALSWYSA
                     ALDVASDDEPSSTSSSSRVTSPPAFLGSYALGTQAQALARAYVVTAQLQQHFQPLMAKL
                     QRISASSSPGACSPSTASLSSVSSCQSSASGSAVVECQQRALQEALEDVEAKIDGIKRA
                     "
     source          1..22797
                     /db_xref="taxon:348901"
                     /isolate="CMW25467"
                     /mol_type="genomic DNA"
                     /organism="Cercospora zeina"
     misc_feature    <1..>22797
                     /note="CTB gene cluster"
     protocluster    1..22797
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[10056:17118]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10057..17118
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..22797
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..22797
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001542"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22797
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            join(<3053..3171,3284..>3938)
                     /gene="CTB7"
                     /product="oxidoreductase"
                     /pseudogene="unitary"
     gene            <3053..>3938
                     /gene="CTB7"
                     /note="ORF3"
                     /pseudogene="unitary"
     mRNA            <4546..>5931
                     /gene="CTB5"
                     /product="oxidoreductase"
     gene            <4546..>5931
                     /gene="CTB5"
     CDS             4546..5931
                     /codon_start=1
                     /gene="CTB5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 157.9;
                     E-value: 9.6e-48)"
                     /gene_kind="biosynthetic-additional"
                     /product="oxidoreductase"
                     /protein_id="ARU80378.1"
                     /transl_table=1
                     /translation="MGSYFSLKNSDLHPSCIALPRSAEDVSKAVQTLSLGAHKWEGKCQ
                     FGVRGGGHTPFKGAASTDNGIVLDLLHMPSAGISPDYETITVSPSTTWDLVYEVLDAHN
                     RSTLGTKVAGIGVGGASTSCGVSYFSPRYGYICDMVENWEVVLATGDIVNANAQENADL
                     WKALRGGINNFGVVTAVTLKTFEQGAFWGGQTFHSIDTRKEHFQNHAELASAPSYDPYA
                     HYINTLVLANMTGGHWFIGNSIQYTKSDPPVAEPEVFKPFLQTKRTPIFPGAPEDTLRV
                     DNVTSFSREYAANTLYPQRWQFACISFAPDADFMETFFQLADAAMRQYVSLPGFKLILN
                     YQPAPTIQLERNRAIDSLGPIQTEGNIVFVHWAVSYDESEAHTDDAITTSVQQLFHAAN
                     AKAKELGVYRHYIQPTYADSWQNPFEFRSKSTVEELVATSKKYDPLQVFQNQVPGGFKL
                     PTV"
     mRNA            complement(join(<6605..8725,8819..9070,9125..>9370))
                     /gene="CTB3"
                     /product="cercosporin toxin biosynthesis protein"
     gene            complement(<6605..>9370)
                     /gene="CTB3"
     CDS             complement(join(6605..8725,8819..9070,9125..9370))
                     /codon_start=1
                     /gene="CTB3"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 192.9; E-value: 1.7e-58)"
                     /gene_kind="other"
                     /product="cercosporin toxin biosynthesis protein"
                     /protein_id="ARU80379.1"
                     /transl_table=1
                     /translation="MMQFQRDLEASLEAVSTNAQKLLAYLESCKDVQNLNTSLPKDPLD
                     DCDAPTQAARAQLAEAATRVLELSIRPQDYLEHLQNGYQNLTCIRWLVELNILDHVPHS
                     GTISYSDLASKASVPPMQLRSVCRMAICNGFLQEPEANQVCHSRISALFARDESYLGWA
                     RWMVNYSVPSAYKLSDATRSWGETVAKDQTAFNLGMDVKVPFFDHLRQTPEMKDAFAAY
                     MRNVTSNETWGLQHAVSGFDWASLRPGAKVVDVGGSLGHGSIAIAKQHTHLNFIVQDLP
                     ETIAGARKEIAQDSKIDDSVKSRIQYMEHDFFGEQPVKDADVYFLRMICHDWPDNEAKI
                     ILSQIRAAMKPGAQIVIMDTILPQPGTISVLQEQQLRIRDLTMMEVFNAKEREYEDWSA
                     LMQSAGLEISHVNQPLNSVMGLLTVRSADKPALPSAGPVARELSLAVPTSGRSEIAKPV
                     LITGAGIAGLCLAQALKKAGIDFRVFERDPHIDARPQGYRLKFEADAAQSLKNILPDRV
                     HEAFELSNAITAVGETDFNPLNGTIIHSRTGGGLSGKQGLYATFTVDRKAFRTQLMTGI
                     EDKISFGKELAYYKTDEATSTVTAEFKDGTHFTGSFLAGTDGLHSVVRKTCVPNHRIVD
                     TGAACIYGKTVMTPEFLARFPEKGLRFMTVCSDVAPMLQSCLIGDSPVTLLLEPIRFSE
                     ASRARHSELPPDYVYWALIGPTERFGSPEVTAMKNFVSLEQAAQQAAQLSLAVTEEWHP
                     SIRALFELQDTKQASLIRVASTIPDVPSWEPHSNVTLLGDSIHPMSPCGGVGANTAIVD
                     ADALAQVLVEHGTKPSVKAIAEFEAAMRMRAKKNICRSEIGSKRMFGQKDLVDCADFGF
                     Q"
     CDS             join(10057..10349,10401..10704,10767..11544,11592..11743,
                     11797..11845,11893..12076,12132..14406,14456..14668,
                     14723..16386,16443..17118)
                     /NRPS_PKS="Domain: SAT (9-250). E-value: 1.9e-64. Score:
                     209.3. Matches aSDomain: nrpspksdomains_CTB1_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (383-818). E-value:
                     1.2e-145. Score: 477.5. Matches aSDomain:
                     nrpspksdomains_CTB1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (924-1214). E-value: 1.1e-79.
                     Score: 259.7. Matches aSDomain:
                     nrpspksdomains_CTB1_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1298-1618). E-value: 1.8e-94. Score:
                     308.5. Matches aSDomain: nrpspksdomains_CTB1_PT.1"
                     /NRPS_PKS="Domain: PP-binding (1680-1744). E-value:
                     1.7e-12. Score: 39.6. Matches aSDomain:
                     nrpspksdomains_CTB1_PP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1790-1849). E-value:
                     5.4e-13. Score: 41.2. Matches aSDomain:
                     nrpspksdomains_CTB1_PP-binding.2"
                     /NRPS_PKS="Domain: Thioesterase (1936-2188). E-value:
                     2.5e-29. Score: 95.2. Matches aSDomain:
                     nrpspksdomains_CTB1_Thioesterase.1"
                     /codon_start=1
                     /gene="CTB1"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 69.7; E-value:
                     3.2e-21)"
                     /gene_kind="biosynthetic"
                     /product="polyketide synthase"
                     /protein_id="ARU80380.1"
                     /sec_met_domain="PP-binding (E-value: 6.8e-14, bitscore:
                     41.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-80, bitscore: 259.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.4e-153, bitscore:
                     500.5, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGDDTQMRVLAFGDQTYDCSEAVSQLLRVRDDAVVVDFLERSCAV
                     LKSELARLSSEQQRENPRFAILAELVPPYRAGTLNPALSQALSCIAQLGLFIRQHSSGQ
                     AAYPTARDSCLTGVCTGLLSAVAVGCASSVTALVPLALHTVAVAVRLGARAWEMGRCLA
                     DVRRDAQSRYASWTAAVGGVSPQDLRERIAGYAKEQALSPISVPFVSARVGPSSGSVSA
                     PPAILDGFLSTLPGPLTGTRLPITAPYHASHLFTSDDVQHVTDCLPRSESWPAVQVPLI
                     SFSRDEVALPGASFPAAMNEAVRDCLIRPIALDRMAVSIADYARSIGKDHVLPVPFALS
                     FSDKLGPQVNSHLPGAKAPTLQAASTTIPPSVAAGQEPLSKSPIAILAASGRFPQSSSM
                     DQFWDVLINGIDTHELVPPSRWDAAAHVSEHPKAKNVSGTGFGCWLHEAGQFDAAYFNM
                     SPREAPQVDPAQRLALLTATEALEQAGIVPDRTSSTQKNRVGVWYGATSNDWMETNSAQ
                     NIDTYFIPGGNRAFIPGRVNFHFKFSGPSYTIDTACSSSLAALHMACNALWRGEVDMAI
                     VGGTNVLCNPDMTAGLDRGHFLSRTGNCKTFDDEADGYCRGEAVVTLILKRLPDAQSDK
                     DPIQAVIRGIATNHSAEADSITRPHAGAQQNLFQQVLTETGISANDISVCEMHGTGTQA
                     GDNGETTSVVETLAPLNRSGCAVRPSDKKLYIGSAKSNVGHGESAAGVTSLAKVLLMLK
                     HSKIPPHIGIKTKLNHRLPDIAARNTHIPRAEVAWPRPENGKRRVLLNNFSAAGGNTCL
                     VLEDAPEVEQFQELDPRLHHIVTLSAKTADSMASNLMNMITWIDQNSGDSKNTLPRLSY
                     TTTARRMHHKHRAVAVGTDLLQIRTSLQEQLDRRMAGEKSVPHPPKGPSFVFAFTGQGS
                     AFAAMGADLYQHFATFRSDIARYDQICERMSLPSIKAMFEDDQAFLTASPTVQQLTHVC
                     LQMALYRLWKSFGIQAKAVVGHSLGEYAALYAAGVLSQSDVLYLVGRRAQLMEQHLSQG
                     THAMLAVRAKEEAIVAAIAGPPGDAYEFSCRNGEQRNVLGGTVDQINAAKSALETKKIR
                     CQYLDTPMAFHTAQVDPILPELLQVAAACSIQEPQIPVISPTYGRVIRNDIQPEYFTHH
                     CRRPVNMVDALESAIEEGLLDKNTIGLELGPAAVVTQLIKEAVGTSMQAFASINKDKDT
                     WQLMTHALARMYLAGAGVEWSRYHEDFSGAQKVLELPAYGWTLKNYWLQYVNDWSLRKG
                     DPPTIVTASNLELSPSIHKVVTNTINPSSDGELVVDADLSREDLHPMVQGHQVYGVPLC
                     TPSVYADIAMTLGEYIRKIIKPGQIAQTAVEVAEMNIQSALVANSTGKVQLLRTCAKFD
                     PKAQIASCTFSTVKEDGNSVIEQHANCQIRFFDLENEKRGLRDAAIAAQARMGALKAQI
                     GQDDNTYRFSKGMIYKMIGQLADFDEKYRGLCAITLDNDQMEASGTVSFKGIPNDGKFH
                     TSPAYLDALSQLGGFVMNGNEGLDLEKEVFVNHGWGSMCFFAALDPAMTYYTHVKMTQG
                     KDKLWTGDVLIFDGKQALIGIVRGVALQGVPKRLMHYIVTAANKKASGGTAPAEKKVST
                     PVAPTRPAIQRKNASIPPPSTQSTVQTKTNNTPSVSALIAPALEIVSEEIGMPIDELKD
                     DIDFTDAGLDSLLSLVISSRMRDQLGIEFESAQFMEIGSIGGLKQFLTKLSPPVAVAVA
                     TAVEVVKEEALAALEELASPTSDEIGAVWRDALKILTEESGLTNDELTDDVSFTDVGVD
                     SLMSLVITSRLRDELDIDFPDRALFEECQTISDLRKKFSLPTEYLDSTSTEANAGHTTP
                     QLTDSSSSSPSSSVYEGETPMTDLDEVFDSPPAQKKPGPPKQQIPPAWSMYLQGSQKRS
                     KEILFLFPDGAGAATSYLSLPRLSPDIGVVAFNSPFMKTPHKFADHTLPEVIASYIEGI
                     RGRQPQGPYHLGGWSAGGILAYAVAQELISAGEEISTLLLIDSPSPIKGLDRLPTRFFD
                     HCTNVGLFGTELSRGSGGSKTPPEWLMPHFRASIELLHDYHAPPMKPGNKTKVMLIWAG
                     ECAFDGVRYAHLPPSSGDTDEDTEGMKFLTEKRKDFGATEWSGLFPGNDVDARVVESEH
                     HFSMMRDGGAQTLVEHMRDGLGIVAS"
     mRNA            join(<10057..10349,10401..10704,10767..11544,11592..11743,
                     11797..11845,11893..12076,12132..14406,14456..14668,
                     14723..16386,16443..17242)
                     /gene="CTB1"
                     /product="polyketide synthase"
     gene            <10057..17242
                     /gene="CTB1"
     aSDomain        join(10084..10349,10401..10704,10767..10919)
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_SAT.1"
                     /evalue="1.90E-64"
                     /label="CTB1_SAT.1"
                     /locus_tag="CTB1"
                     /protein_end="250"
                     /protein_start="9"
                     /score="209.3"
                     /tool="antismash"
                     /translation="LAFGDQTYDCSEAVSQLLRVRDDAVVVDFLERSCAVLKSELARLS
                     SEQQRENPRFAILAELVPPYRAGTLNPALSQALSCIAQLGLFIRQHSSGQAAYPTARDS
                     CLTGVCTGLLSAVAVGCASSVTALVPLALHTVAVAVRLGARAWEMGRCLADVRRDAQSR
                     YASWTAAVGGVSPQDLRERIAGYAKEQALSPISVPFVSARVGPSSGSVSAPPAILDGFL
                     STLPGPLTGTRLPITAPYH"
     CDS_motif       10483..10515
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0001"
                     /evalue="2.30E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="CTB1"
                     /protein_end="136"
                     /protein_start="125"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="VAVGCASSVTA"
     CDS_motif       10800..10859
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0002"
                     /evalue="8.40E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="CTB1"
                     /protein_end="230"
                     /protein_start="210"
                     /score="-3.4"
                     /tool="antismash"
                     /translation="ARVGPSSGSVSAPPAILDGF"
     aSDomain        join(11319..11544,11592..11743,11797..11845,11893..12076,
                     12132..12825)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.20E-145"
                     /label="CTB1_PKS_KS.1"
                     /locus_tag="CTB1"
                     /protein_end="818"
                     /protein_start="383"
                     /score="477.5"
                     /tool="antismash"
                     /translation="IAILAASGRFPQSSSMDQFWDVLINGIDTHELVPPSRWDAAAHVS
                     EHPKAKNVSGTGFGCWLHEAGQFDAAYFNMSPREAPQVDPAQRLALLTATEALEQAGIV
                     PDRTSSTQKNRVGVWYGATSNDWMETNSAQNIDTYFIPGGNRAFIPGRVNFHFKFSGPS
                     YTIDTACSSSLAALHMACNALWRGEVDMAIVGGTNVLCNPDMTAGLDRGHFLSRTGNCK
                     TFDDEADGYCRGEAVVTLILKRLPDAQSDKDPIQAVIRGIATNHSAEADSITRPHAGAQ
                     QNLFQQVLTETGISANDISVCEMHGTGTQAGDNGETTSVVETLAPLNRSGCAVRPSDKK
                     LYIGSAKSNVGHGESAAGVTSLAKVLLMLKHSKIPPHIGIKTKLNHRLPDIAARNTHIP
                     RAEVAWPRPENGKRRVLLNNFSAAGGNTCLVLEDAP"
     aSModule        11319..15706
                     /complete
                     /domains="nrpspksdomains_CTB1_PKS_KS.1"
                     /domains="nrpspksdomains_CTB1_PKS_AT.1"
                     /domains="nrpspksdomains_CTB1_PT.1"
                     /domains="nrpspksdomains_CTB1_PP-binding.1"
                     /iterative
                     /locus_tags="CTB1"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       11946..11993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0003"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="CTB1"
                     /protein_end="559"
                     /protein_start="543"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPSYTIDTACSSSLAA"
     CDS_motif       12190..12228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0004"
                     /evalue="3.80E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="CTB1"
                     /protein_end="619"
                     /protein_start="606"
                     /score="13.5"
                     /tool="antismash"
                     /translation="FDDEADGYCRGEA"
     CDS_motif       12550..12594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0005"
                     /evalue="1.50E-02"
                     /label="PKSI-KS_m6"
                     /locus_tag="CTB1"
                     /protein_end="741"
                     /protein_start="726"
                     /score="8.4"
                     /tool="antismash"
                     /translation="GSAKSNVGHGESAAG"
     CDS_motif       13144..13191
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0006"
                     /evalue="8.50E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="CTB1"
                     /protein_end="940"
                     /protein_start="924"
                     /score="12.3"
                     /tool="antismash"
                     /translation="FTGQGSAFAAMGADLY"
     aSDomain        13144..14013
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_PKS_AT.1"
                     /evalue="1.10E-79"
                     /label="CTB1_PKS_AT.1"
                     /locus_tag="CTB1"
                     /protein_end="1214"
                     /protein_start="924"
                     /score="259.7"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="FTGQGSAFAAMGADLYQHFATFRSDIARYDQICERMSLPSIKAMF
                     EDDQAFLTASPTVQQLTHVCLQMALYRLWKSFGIQAKAVVGHSLGEYAALYAAGVLSQS
                     DVLYLVGRRAQLMEQHLSQGTHAMLAVRAKEEAIVAAIAGPPGDAYEFSCRNGEQRNVL
                     GGTVDQINAAKSALETKKIRCQYLDTPMAFHTAQVDPILPELLQVAAACSIQEPQIPVI
                     SPTYGRVIRNDIQPEYFTHHCRRPVNMVDALESAIEEGLLDKNTIGLELGPAAVVTQLI
                     KEAVGTSMQ"
     CDS_motif       13375..13497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0007"
                     /evalue="1.70E-15"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CTB1"
                     /protein_end="1042"
                     /protein_start="1001"
                     /score="49.0"
                     /tool="antismash"
                     /translation="GIQAKAVVGHSLGEYAALYAAGVLSQSDVLYLVGRRAQLME"
     aSDomain        join(14266..14406,14456..14668,14723..15328)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_PT.1"
                     /evalue="1.80E-94"
                     /label="CTB1_PT.1"
                     /locus_tag="CTB1"
                     /protein_end="1618"
                     /protein_start="1298"
                     /score="308.5"
                     /tool="antismash"
                     /translation="PSIHKVVTNTINPSSDGELVVDADLSREDLHPMVQGHQVYGVPLC
                     TPSVYADIAMTLGEYIRKIIKPGQIAQTAVEVAEMNIQSALVANSTGKVQLLRTCAKFD
                     PKAQIASCTFSTVKEDGNSVIEQHANCQIRFFDLENEKRGLRDAAIAAQARMGALKAQI
                     GQDDNTYRFSKGMIYKMIGQLADFDEKYRGLCAITLDNDQMEASGTVSFKGIPNDGKFH
                     TSPAYLDALSQLGGFVMNGNEGLDLEKEVFVNHGWGSMCFFAALDPAMTYYTHVKMTQG
                     KDKLWTGDVLIFDGKQALIGIVRGVALQGVPKRLMHYIV"
     aSDomain        15515..15706
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_PP-binding.1"
                     /evalue="1.70E-12"
                     /label="CTB1_PP-binding.1"
                     /locus_tag="CTB1"
                     /protein_end="1744"
                     /protein_start="1680"
                     /score="39.6"
                     /tool="antismash"
                     /translation="LEIVSEEIGMPIDELKDDIDFTDAGLDSLLSLVISSRMRDQLGIE
                     FESAQFMEIGSIGGLKQFL"
     aSDomain        15845..16021
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_PP-binding.2"
                     /evalue="5.40E-13"
                     /label="CTB1_PP-binding.2"
                     /locus_tag="CTB1"
                     /protein_end="1849"
                     /protein_start="1790"
                     /score="41.2"
                     /tool="antismash"
                     /translation="ILTEESGLTNDELTDDVSFTDVGVDSLMSLVITSRLRDELDIDFP
                     DRALFEECQTISDL"
     aSModule        15845..17094
                     /domains="nrpspksdomains_CTB1_PP-binding.2"
                     /domains="nrpspksdomains_CTB1_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="CTB1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        join(16283..16386,16443..17094)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB1_Thioesterase.1"
                     /evalue="2.50E-29"
                     /label="CTB1_Thioesterase.1"
                     /locus_tag="CTB1"
                     /protein_end="2188"
                     /protein_start="1936"
                     /score="95.2"
                     /tool="antismash"
                     /translation="LFLFPDGAGAATSYLSLPRLSPDIGVVAFNSPFMKTPHKFADHTL
                     PEVIASYIEGIRGRQPQGPYHLGGWSAGGILAYAVAQELISAGEEISTLLLIDSPSPIK
                     GLDRLPTRFFDHCTNVGLFGTELSRGSGGSKTPPEWLMPHFRASIELLHDYHAPPMKPG
                     NKTKVMLIWAGECAFDGVRYAHLPPSSGDTDEDTEGMKFLTEKRKDFGATEWSGLFPGN
                     DVDARVVESEHHFSMMRDGGAQTLVEHMRD"
     CDS_motif       16450..16506
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0008"
                     /evalue="5.50E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="CTB1"
                     /protein_end="1992"
                     /protein_start="1973"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="HKFADHTLPEVIASYIEGI"
     CDS_motif       16516..16590
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CTB1_0009"
                     /evalue="2.90E-14"
                     /label="NRPS-te1"
                     /locus_tag="CTB1"
                     /protein_end="2020"
                     /protein_start="1995"
                     /score="45.3"
                     /tool="antismash"
                     /translation="QPQGPYHLGGWSAGGILAYAVAQEL"
     3'UTR           17119..17242
                     /gene="CTB1"
     mRNA            <17622..>18980
                     /gene="CTB2"
                     /product="O-methyltransferase"
     gene            <17622..>18980
                     /gene="CTB2"
     CDS             17622..18980
                     /codon_start=1
                     /gene="CTB2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 176.1; E-value:
                     1.9e-53)"
                     /gene_kind="biosynthetic-additional"
                     /product="O-methyltransferase"
                     /protein_id="ARU80381.1"
                     /transl_table=1
                     /translation="MASRIEADGLFELTAELVSASSKLNKFLDQKGLPQPSFDAPAPSV
                     ALNTENKPYYDARSAIVEAAEQIIRLVRGPRDTLLALSFEHCATASMQVIFRYKFASHI
                     PLHGSTTYSKIAAAVGEGVTAALVERTIQHCASFGLFETIPGGYVTHNATSSLLVTDPD
                     LEAWMYLSAVIAYPAGAAIPKAVEQYGVSMEADEAGYGASIGRKIAQFQRFREPDGKKD
                     HEMFARAMRGIAAGGAYDFRHAVDGGYPWHLLAKGAGHLVVDVGGGPGHVAMALAEKYP
                     TLRFEVQDLPETVQVGAKNCPGHLQKRVAFRAHDFMTLQPAHEVQGDEGIAYFARFILH
                     DWSDKYATKIVQQLASGLRPQDRIILNEVVVPESGQVGRETQRRMHDRDLLMLMNLNGR
                     ERTQSAFEAIFASVTPKLRLQRVHYPEQGELSLIEVTLDGVELPGHGDAVKWH"
     3'UTR           complement(19214..19412)
                     /gene="CTB4"
     mRNA            complement(join(19214..19557,19610..20054,20106..20671,
                     20727..>21115))
                     /gene="CTB4"
                     /product="MFS transporter"
     gene            complement(19214..>21115)
                     /gene="CTB4"
     CDS             complement(join(19413..19557,19610..20054,20106..20671,
                     20727..21115))
                     /codon_start=1
                     /gene="CTB4"
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 78.7; E-value: 5.7e-24)"
                     /gene_kind="transport"
                     /product="MFS transporter"
                     /protein_id="ARU80382.1"
                     /transl_table=1
                     /translation="MAPSIADDDLDGLKRPHVTFSSGAASPPQSTAEAMEFEEQILETI
                     KSEAYLVDWVGDNDKGDPQNLPYWRKWVITMSLALYALSTTFSSSVFGAATHVLAKEFA
                     LPAETVVLGCTSLFMVGFATGPVFWGPFSEAFGRTRPLIAGYLAFAILQLPIADAQSPT
                     TIFCLRYLQGLTGAAPSSILSGTLADIWSPRERGFAMPTVGAFLTIGPILGPLIGSVLV
                     QSALGWRWIANVVAIASFLIAICTFPFMPETYSPLLLARRAERMRHMTRNWAYRSKSEE
                     ARSSLGDFAERYLLRPARMLALEPILLMMTMYVSVSFVKGLLYNFFLAYPTSFIQERGW
                     DQISASLPLISILVGVIMAGALLSFTTNSRWAPNANEGRPQETRLLLMMVGAVSLPAGM
                     FCFAWTSSATMNPWPQILSGVPTGFGIHLINMQGLNYIIDSYKIYANSAVAANTFLRSL
                     FAAGFPILATSMYATIGVKWGTTILALLAVTMIPIPILFYYFGANIRAKSKWQPPM"
     mRNA            complement(<21733..>22797)
                     /gene="CTB6"
                     /product="reductase"
     gene            complement(<21733..>22797)
                     /gene="CTB6"
     CDS             complement(21733..22797)
                     /NRPS_PKS="Domain: NAD_binding_4 (7-206). E-value: 2.4e-10.
                     Score: 31.8. Matches aSDomain:
                     nrpspksdomains_CTB6_NAD_binding_4.1"
                     /codon_start=1
                     /gene="CTB6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 91.8;
                     E-value: 8.8e-28)"
                     /gene_kind="biosynthetic-additional"
                     /product="reductase"
                     /protein_id="ARU80383.1"
                     /transl_table=1
                     /translation="MADSRVLLTGATGFIGFRILVELLHQGYNVRAVVRSPTKGRWLES
                     RLAAVTKGANWKAGFQTTIVTDFVTEGAFDQAAENTSYIIHVASPIVSSDNPEDWEHDF
                     KRVAVRGSIGILEAAKRSATVRRIVITSSMVALFTPKAIFAEPSKVPLDAESRIPEMEP
                     PYAHKMMAYQAGKIASLNSAEAWIRREQPAFDLIHMHPSFVTGRDDLATTREDLRKFSS
                     NWHSMQIVLGHKNPVGKPLLTCHNDDVARCHVSALNPKIAGNQSFLISCSPEDGSEWDD
                     VKEFVQRDYPEAVAEGVLPNDGHMPTVNKGVRFDVRKTEETFEFKHTPYEAQVLDVVKQ
                     YLELPEKDEGVEVV"
     aSDomain        complement(22180..22776)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CTB6_NAD_binding_4.1"
                     /evalue="2.40E-10"
                     /label="CTB6_NAD_binding_4.1"
                     /locus_tag="CTB6"
                     /protein_end="206"
                     /protein_start="7"
                     /score="31.8"
                     /tool="antismash"
                     /translation="LTGATGFIGFRILVELLHQGYNVRAVVRSPTKGRWLESRLAAVTK
                     GANWKAGFQTTIVTDFVTEGAFDQAAENTSYIIHVASPIVSSDNPEDWEHDFKRVAVRG
                     SIGILEAAKRSATVRRIVITSSMVALFTPKAIFAEPSKVPLDAESRIPEMEPPYAHKMM
                     AYQAGKIASLNSAEAWIRREQPAFDLIHMHPSFVTG"
ORIGIN
        1 tcacgcccgt ttgatgccgt caatcttggc ctcgacatcc tccaacgcct cctgcagcgc
       61 gcgttgctgg cactccacca ccgccgatcc gctggccgat gactgacacg atgacacgga
      121 gctcagcgac gccgtcgacg gggagcacgc gcccggcgac gacgatgccg acgatgccga
      181 cgatgacgac gacgacgatg acgacggcgg cggcggcgac gaccacgaga tgcgctgtag
      241 cttcgccatg agcggctgga aatgctgctg cagctgcgcc gtcaccacgt atgcgcgcgc
      301 cagcgcctgt gcctgcgtcc cgagcgcgta gctgccgagg aaggccggtg ggctcgttac
      361 tcgcgacgaa ctggacgtgc tcgacggctc gtcgtcgctc gcgacatcca acgccgccga
      421 gtaccacgac aacgctttgt ggatcgccag gaaggctgcc gtgaggactt cgtggttgcg
      481 gcagcacggc cgacagtcga ggatgctgga cagtcgctcc agcgccgtgc gattgctgtc
      541 caggacatgg tcgaaatcgc gcacgtcttg gtctgccgag cccgccgcta tggggcacgc
      601 cgaaccggag acgtgcagtt ccgagaagat ctggagcgcc gtgctgatac accctccccc
      661 gcccccgcca tggcccgtcg acccgccgcc ccgttgactg cggggcgacg ctgatgaaga
      721 aggccgtgtc gacgcctcca tgcccacttt ggacagtccg cctgtcgata ttccaaacag
      781 cttcgctacc tcggtgggtg acaaaggtgt actatcgaca ccactcaagc ctttggcctc
      841 gggctccgct tcgaacccac ctgcactgaa aaagtcaaaa tattgcatgt ccatatcctc
      901 cacgttcgtc actaccggtt gggcccacat gctgtcatcg aacgcgtcca gaccatcgag
      961 catcgcgagg tcgctcagcg agggcgatag ccggccatgg atgacgatgg aatccgctga
     1021 agcactcgag gttggagcca tgggttttag cgtgtcaggc tcgggtgttg ctcgaatcga
     1081 cggacgcctg gtgccggtac gccgcgagat gttgtactgg cataacagtc ctttattgac
     1141 gcagcgggca catgcgggac gttctttggt gcagcggatc ttctgactag agcactgctg
     1201 aagaggtcag cggagcaggg ctgcgagtcg cgctgacaag catacgtgag tacacgattc
     1261 cctgatcttc gggcgcttga acgatgtgtc ccgcgtgtta ggcatgtcgc ttgcgccgcc
     1321 cctcgccatg gtggaaagtg tatcggacag tctcgtcaag gatgtaggaa gcagggcgat
     1381 cggaatcgaa gtctttccaa aggtctacca cagctcaagc tacctggaca tcacatctgc
     1441 acatatatgt cgtctcgcaa ccagcgcgca ccggtgctgg catcctagca ggtaaatcgg
     1501 gagcgacgac aacaagtcca atctggttct cgctcatcca catacgctac gaagcgaggg
     1561 tcgaaacgcg aggccatgct gcgcccgtcg aaatgggttc gcatgctgtg cctgcaacta
     1621 gctcagcacg ttgggagcat gtgtgcccag tgagggtatc ccagcatggg cgcttggaat
     1681 cgcatgtaca tagcgtccca gcaaccttgg tacaggaaaa cggaggatct tctggggaac
     1741 cacgccccct gtgccccgag tgtggcggtg cgcatcagaa gttccagaag cgtgcgcgcg
     1801 accgtggagg aaatgcaagc accgtgcaac gccgaacaca ccatggagca cgaggttcgt
     1861 ttcagttgag tacgatgcac cagtccgccg gatcggcaga cccagtgccc gtcctactac
     1921 tggacgcgca gacgtggaac tccccgaccg tggctcgaag cgtagaaagg agcaatgctc
     1981 cgagcgtgca gtccccacac atcgctccgt cgcccgcagc tactagccag ggcgttgtac
     2041 agtaactgac cctcgcggcg tgttgaaagg acagagattg atctgcaccg agccgttccc
     2101 atcctgggcg cacccacgtc ctttggagcc acgactccac gaggatgttg acgtcgtcgc
     2161 ccgcgcttga ggaggagcaa cacaagggcg taatgctgga atggctcaca ggtgcaaggt
     2221 gcaaatcgat gtcgagtcca gccgaaggac cgcggaccgc ggaccgcgca cacggggcct
     2281 cgttcaccag tcacatgaac gtggcacttc ggcatttgtg tgctacattt ggtgctctgc
     2341 tatctccatc tctctgccgc tgctccctgt cgtgctcttc gagtctccac atctaccagg
     2401 ctcggagttc ttgccggccc gatcggcttc cgccggcacg tgacggcagc aatcggatta
     2461 ggccaaactt agactagcgg accagcggca attccgacga taacgcagag gccggcgctc
     2521 gtagagatgc gacggcctcg ttggccttat caaaatatca tgtttggagg aaaacggctt
     2581 gcttggcgct cgactgtgct ggtggtgcca ccaaccacca tctcgtcggt ccggcgcgtt
     2641 ctggccgtac ggctgatgtg caggattgtt gctctctacg acctgcggga agcattggtc
     2701 cactggagcc gcgagcgtac gccgtgcgga atacatctcc cacatgatgt aattgtgaaa
     2761 tgcaagtcgg tcgacgtcac gaagaacaac caacaaagca attgtggaga gcgatcatgc
     2821 ggcgtgtgga aaacataaaa acagcggatg ggtcgaggac cagactctgt cccacacatc
     2881 caggcgtgcg aacatcaccc ccgctcgacc gtcacggcgt ccccgaaccg aagagtgctt
     2941 gtgaatggcg cgggtccggc aggcgcagcg acggctttct ggcttgcgaa cggcggcttc
     3001 gaagtgctgg tgacagaacg ctccatgagc cggccctacg gacaaggggt cgatgtcacg
     3061 ggacgcgcag tcgacatcat cacaaagatg ggcttggagc agcgcattcg agacagcacc
     3121 acgggcgaag aaggcctatg tcgccttctt ctctatgcca ggtgacccaa cgtaagtaag
     3181 ctcccccatc atgtctggct gtgcatatgt gagcaaggat gggaacactc ggagcgcaat
     3241 tgagaagacc ggtctcagag tcgctcacct aacgatcgat caggtacgat acgccggtgg
     3301 gaaagctcca acacgccaac aaaggtcgag ggattttcat ccgtcccatc gataagaaag
     3361 gcacccggag ctcgtgttat ctgatgtcgt ggacggaaga ccaagacctg gcgcaagttg
     3421 cacgaacggg atcacaggag gatcgaaaag cccttctgga caagatgttc cgaggattca
     3481 acggcccatt gggcaagcgg gccgttgagg gcatgcttga cgctgacgat ttctacttca
     3541 cccgcatcgt acaaatcaaa ctcgatatgt ggcatcgcgg gcgagcggcg ctgctaggcg
     3601 atgctgccta ttcgccttca ccactcacag ggcaaggtcc aactcttgcc atcactggcg
     3661 cctacgtcct cgcgggggag atggcgaaaa gtccggacga tctacaacag gccttcgcct
     3721 catatcatcg cgtactcaaa gacttcgcca gcgagtcgca gcaaattcca cttggaggtc
     3781 aagctccaaa gttagcgtta ccacagtccg actggggcat ctggcttctt cgcttcttct
     3841 acaaaatcat tgccttttcg ggactctggc gattgctcaa tttcgggaat gaaactgtca
     3901 aggttgagct ccctgagtac aatttggggc caaactgatg caaccttttg acgaatcaat
     3961 tttgcaatgc aaccagagtc ccaaaaaata gaggtccaga tacacgtacg gcagatactt
     4021 agcgccatca ttcacggcag ctttctcgtt tcccgacccc gttcgcctca caatcaccga
     4081 tcacgtgctt gggcccactc gcgcagacat tagacggccg ggaaacaacg ccgagcttaa
     4141 ggtggccgat ttgggcaaca ttggctgacc acacggccgg cgctacgctt ctgatgccca
     4201 aagacctgca ttgatatcca gtgtcctgtt cccgcagctc aatcatttgc tgaaatttgt
     4261 tatcacgaag tgattcgtcg ccatgttggg actcaatctc caacaagtcc tctccggcgt
     4321 tccgacgata tcaagcctcc tcaatggcgg aatctcacat gaatatgctc cagagagcag
     4381 tgcatgggcc tcagtggcag catcaaagtc ttgtgtcagt gtccagttgt ctgccttgct
     4441 gatcgaaatg tcaaacactg acgccgaaca cagtgcgatg cactagccaa aagcctgggc
     4501 aagaatgcag tggtcttccc atatgatgcg gcgtactccc aatcaatggg ctcatatttc
     4561 agcttgaaga atagcgacct ccatcccagt tgtatagcgc ttccccgatc cgcagaagat
     4621 gtatcgaagg cagtgcaaac actatccctg ggcgcccaca aatgggaggg caaatgccaa
     4681 ttcggagttc gaggtggcgg acacacacct ttcaaaggag ctgcaagcac ggacaacggc
     4741 attgtgctgg atcttctaca catgccctct gcaggcatct ccccggacta tgagaccata
     4801 acagtatcgc ccagcacgac ctgggatctg gtatacgaag ttctcgacgc tcacaatcga
     4861 agcacactgg gcaccaaagt cgccgggatt ggcgtcggag gagcatcaac gagctgcgga
     4921 gtgtcgtact tctcgcctcg gtatgggtac atctgcgaca tggtagagaa ctgggaagtc
     4981 gttctcgcca ccggcgacat tgtcaatgcc aacgcacaag aaaacgccga tctttggaaa
     5041 gcgctgcgag ggggaatcaa caacttcggc gtcgtcaccg cagtcacgct caagaccttt
     5101 gagcaaggtg cattctgggg tggtcagacc tttcactcaa tcgacacgcg caaagagcac
     5161 ttccaaaatc acgcggaact cgcttcggcg ccttcttacg atccatacgc acactacatc
     5221 aatactctcg ttttagccaa tatgactggg ggtcactggt tcatcggcaa cagcattcag
     5281 tataccaaga gcgacccacc cgtggctgag cccgaagtct tcaagccatt cctccagacc
     5341 aagcgaaccc caatcttccc aggtgcacca gaagatactc tccgcgtgga caacgtcacc
     5401 tccttttctc gcgaatacgc agcaaacaca ttataccctc aacgctggca attcgcctgc
     5461 atcagcttcg ctcccgacgc agacttcatg gagaccttct tccaactggc cgacgcagcc
     5521 atgagacaat acgtcagctt accaggcttc aagctcattc tcaactacca gcccgcccca
     5581 accatccagc tcgaacgcaa ccgagcaatc gactctttag gccccatcca aaccgaagga
     5641 aacatcgtct tcgtgcattg ggccgtcagc tacgacgagt cggaagcgca cacggacgat
     5701 gccatcacca cgagcgttca acagctgttc catgccgcta atgccaaggc gaaagagctg
     5761 ggtgtttatc ggcattacat tcaaccgact tatgccgata gctggcagaa ccctttcgag
     5821 ttccgaagca agagcacggt tgaggaactt gttgccacga gcaagaaata tgaccctttg
     5881 caggtctttc agaaccaggt gcccggtggc ttcaagctgc ccacggtttg agtggggagt
     5941 gttggagcgt gagtggttgg catgagctca ggcgagatga catgggacat gatgttttga
     6001 gttacctttt ttctgttttt ttttttgttt tggttttttt taaaacaccg ggaaagtctg
     6061 tcaagattcg atatttattt tttttatagt tggtgaaacc ccccccccca aggtcatgga
     6121 ttggcaaaac atatttgctg ccgcaatttc caagaagtag ttctccccat actcgccacc
     6181 gtttttggtc attgatgaat tcatgcgtcg caagcaaacg gagcgggaga gtgcgaagcg
     6241 cacatgtcac gcgatggaaa agtcatcgcc aaaatcccca cttttttttt cttctcgaga
     6301 ccaacgtaaa cggtctcgtc tcatcaatca acttgagtac gggcagaatg aagcaagaca
     6361 atgcgtatcg ttggccgatc gttctctgga atcacgagaa aggtctcagc tcgcttgctt
     6421 gactacccaa gagcagtttc agaacgtaga aacattcgat gagaacgatt ctgttccgct
     6481 cttactttgc gcgtctgatc agggaattgg ataacttgtt gcctccaggc agcaattcat
     6541 aaaatcagaa gtagctcgta acagcccgaa aagaaatgac aaaatccccg gcttgataga
     6601 ccaatcactg aaatccgaaa tctgcacagt ccacgagatc tttctgcccg aacattcgct
     6661 tgctgccaat ctcacttcta cagatattct tcttggctct catcctcatg gcagcctcaa
     6721 actcggctat cgctttcacc gacggcttcg taccatgctc cacaagcact tgggccaagg
     6781 cgtcggcatc gacgattgcc gtgttcgcgc cgactccacc gcaaggactc attgggtgga
     6841 tgctgtcgcc aagcaaggtg acattcgagt ggggctccca cgatgggaca tcggggatcg
     6901 tggacgccac gcgaatgagc gaggcttgct tggtgtcttg cagctcaaat aacgcacgta
     6961 tggagggatg ccactcctcg gtgactgcga ggctgagctg ggcagcctgt tgtgccgctt
     7021 gctcgagtga gacaaagttt ttcatggccg tgacttcggg cgatccgaag cgttccgtgg
     7081 gtccaatgag tgcccagtag acgtagtctg gtggcagctc ggagtgccga gcacgcgagg
     7141 cttcgctgaa tcgtatgggc tccagtagta aagtgaccgg gctgtcgccg atgagacacg
     7201 attggagcat gggtgcgaca tcgctgcata ctgtcatgaa tcgcaggcct ttctcgggga
     7261 atcgtgcgag gaactccgga gtcatgacgg ttttgccata gatgcaggca gcaccagtgt
     7321 ccacgatacg gtggtttggc acacatgtct tgcggacgac ggagtgtaaa ccatcagtac
     7381 cagccaggaa gcttcctgtg aagtgagtgc catccttgaa ctcggccgtg acggtcgatg
     7441 tggcttcatc cgtcttgtag taagccaatt ctttcccgaa cgagatcttg tcttcaatcc
     7501 cagtcatgag ctgagttctg aaggctttcc ggtcaacagt gaatgtggca tatagtcctt
     7561 gcttgccaga aagaccgccg cccgtgcggc tatggatgat ggtgccgttg agaggattaa
     7621 aatccgtctc gcccacggcg gtaatggcat tcgacagctc gaaagcctcg tgaaccctgt
     7681 ctggcaggat gttcttgaga gactgtgcag cgtctgcttc gaacttcagg cggtagccct
     7741 gcggccgcgc atcaatgtga ggatccctct caaacacgcg aaagtcgatg ccagccttct
     7801 tgagagcctg cgcaaggcac aacccagcga tgccagcgcc agtaatgagg actggcttcg
     7861 caatctcaga gcgaccgctt gttgggacgg ccaacgatag ttcccgggca actggtcctg
     7921 cgctggggag agcgggcttg tcggctgatc ggactgtgag tagacccatt acgctgttga
     7981 gtggctgatt cacgtgtgag atctcaagcc ccgcagactg catcaatgcg ctccagtctt
     8041 catattcacg ctctttggca ttgaagacct ccatcatggt gagatcgcga atgcgcagtt
     8101 gttgttcctg cagcacactg atggtaccgg gctggggaag aatggtgtcc atgatcacta
     8161 tttgtgcgcc tggcttcatt gcagcgcgga tctgagagag aatgatcttt gcttcgttgt
     8221 caggccagtc gtggcaaatc atgcggagaa agtaaacatc ggcatccttg accggctgtt
     8281 cgccgaagaa gtcgtgttcc atatattgga tgcgcgactt gacagaatca tcaatcttgc
     8341 tgtcttgtgc aatctctttg cgagcaccgg caatcgtctc tggcaaatct tggacaatga
     8401 aattgagatg ggtgtgctgc ttagcaatag caatactgcc atgtccgaga gagccaccga
     8461 cgtctacgac tttggcgcct ggccggaggg atgcccaatc aaagcccgaa accgcatgtt
     8521 gaagacccca ggtctcgttc gaagtcacat tccgcatgta tgcggcgaag gcgtccttca
     8581 tttccggggt ctggcggaga tgatcgaaaa acggaacctt gacatccatt cccagattga
     8641 atgccgtctg atctttggcc acagtctcgc cccatgagcg cgtggcatcg ctcagcttgt
     8701 atgcagatgg caccgaatag ttgacctgtg agactgaagg ttagcaatgg tatcattcat
     8761 tctcctggcc ccggctcatc cgaatctcat cgtagaggat gaaagggaag ctactaacca
     8821 tccatctagc ccaccccaga tagctttcat cacgggcgaa cagggcggag atgcgactgt
     8881 ggcaaacttg gttggcttca ggctcttgca agaacccgtt gcatatggcc atgcgacaaa
     8941 cgctcctcag ctgcatgggt ggcacactgg ccttgctcgc caggtctgaa tagctgatgg
     9001 ttccgctgtg aggaacatga tccaatatgt tgagttccac cagccagcgg atgcaggtca
     9061 aattttggta ctgatgcagc ttagatgacg gcaatgacag aggtgcgcga cacaggaaac
     9121 ttaccccgtt ctggaggtgc tccagatagt cttgaggacg gatggatagc tccaagactc
     9181 tggtcgcggc ctcggccagc tgcgcgcgag cggcttgggt tggagcatcg cagtcgtcta
     9241 gaggatcctt tggtagcgag gtgttgagat tttggacatc cttgcaactc tcgagatacg
     9301 ctagcagctt ctgggcattg gtcgacacag cctccagaga ggcctcgaga tcgcgttgaa
     9361 actgcatcat gtgtggcaaa tgattgtgat gacagtaaat ggtaacattg tcgtccggcg
     9421 atgaagctga agtagcagac gttctggccg ggagcagttc catttttcac atttgccgcg
     9481 aacaagttga gtgcgacatc gttccactga gctgcctgtt tgccgaagcg gtcacacgca
     9541 aagtccccgt ccatgtgccg tttgacagtc tccgttgccc accgacgggt gtcgcgtgca
     9601 gtgtggtgtt ttgcgatgtg tggttcgcga cgtatgtcag accaccatgg aacgcggaac
     9661 tgggaagccg ggaatcggtc aaagggcggt atcttctgct tgctgagatg aagaggtcag
     9721 cgatggaacg gcctccgagt ctctcttgct gggggctgtc ttgcacagta gtgttatggt
     9781 attgtggccg gccacgtcga cgacactgtg cgcgaggaac agacgccgag ttctcgtgcg
     9841 gctactttct cagtcctcaa attgtgcgcg cacatcacgc acgccacagc gaccggcgat
     9901 tgatttgacc tacggttgac atggcatata ggtgcagata cgctgtcacg agctcgtgtc
     9961 cagcagtcgc atcaccctcc cagctgcatt ccattctttc aacattcctc tgttgattgg
    10021 tccaacacat tgtcactctt caccacgtct cacgccatgg gagatgacac gcagatgcga
    10081 gtgttggcgt tcggggacca gacatacgac tgcagtgaag cagtgtcaca gctccttcga
    10141 gtccgtgacg atgccgtcgt cgtcgatttt ctcgagcgat catgcgccgt tctcaagtcc
    10201 gagctggccc ggctcagcag cgagcaacag cgagagaacc cccgattcgc cattctggct
    10261 gagctggtgc caccataccg agccggcaca ctcaacccag cgctctccca agcattgtct
    10321 tgcattgcac agttgggcct cttcatccgg tattgcagct cgggtccaga tcacgccgag
    10381 cgcggctaac gcggacgcag acaacacagc agcggacagg cggcctatcc cacggcccgg
    10441 gactcttgtc ttaccggcgt ctgcacggga ttgctgtccg ccgtggccgt cggctgtgct
    10501 tcgagtgtga cggcgctggt gccgctggcg ttgcacaccg tcgccgtcgc cgtgcggttg
    10561 ggcgcccggg cttgggaaat gggacgctgc ctcgccgatg tccgacggga tgcgcagagc
    10621 cgctatgctt cttggacggc ggcggtgggc ggagtcagtc cccaagatct ccgggagcgg
    10681 attgcgggat acgcgaagga gcaggtgagt gatgttccgg gggagctgga ttggtcactg
    10741 ttgttgatgc gacttctcta actcaggcgt tgtcgccaat ctccgtccca ttcgtgtcgg
    10801 cccgtgtcgg cccgtcctcg ggctcggttt cggccccgcc cgcaatcttg gacggcttct
    10861 tatcgaccct ccctggacct ctgacaggaa cacggctgcc catcaccgct ccgtatcatg
    10921 catcacatct cttcacttcg gacgatgtac agcacgtcac agactgcctt cctcggagcg
    10981 aatcatggcc cgcagtgcag gttcccctca tcagcttttc ccgtgacgag gtcgcattgc
    11041 cgggcgccag ctttccggcc gccatgaacg aggccgtgcg agactgcttg atccgcccta
    11101 ttgccctcga ccgcatggca gtgagcattg ccgactacgc ccggagcatt ggcaaagacc
    11161 atgttcttcc ggtgccattt gctctctcct tcagtgataa gttgggtccg caggtgaaca
    11221 gccatttacc aggcgcgaag gctcccacgc ttcaagccgc atcaacgacg atcccgccat
    11281 ctgtagcagc aggacaggag ccattatcaa agtcgcccat cgctatcctc gctgcctctg
    11341 gtcgctttcc gcaatcctca tcaatggacc agttctggga tgtgttgatc aacggcatcg
    11401 atacgcacga gcttgttccc ccatctcgtt gggacgcagc tgctcatgtt tccgaacatc
    11461 ccaaagccaa gaacgtgtct ggcacaggct ttggctgctg gctccacgaa gctggccaat
    11521 ttgatgctgc ctatttcaac atgagtatga aaatccccac gcatgaatgg ctcacgctca
    11581 cgacaaaata ggtccgcgtg aagcgccgca ggttgatcca gcacagcgtc tcgccctatt
    11641 gactgccacc gaagccctcg agcaagccgg cattgttccg gataggactt cgtcaacaca
    11701 gaagaataga gtaggtgtgt ggtatggcgc caccagcaat gatgtgagtg ttacacagac
    11761 tgtacgaaca ttgatcacat attgatatcg ttccagtgga tggaaacaaa tagcgctcag
    11821 aacatcgaca cgtacttcat ccctggtggg tatactttcc catcttcatt agttgcgtac
    11881 taatcaatcc aggcggcaat cgtgcattca tccccggcag ggtcaacttt cacttcaaat
    11941 tcagcggccc ttcttacaca atcgacacgg cctgcagttc cagtctagcc gcattgcaca
    12001 tggcatgcaa tgcattgtgg cgcggcgagg tggatatggc gattgtgggt ggcacgaacg
    12061 tgttatgcaa ccctgagtga gaaaaatgtt tctcagacag taccgtacct tccactgact
    12121 ccttttgtta gcatgacggc tgggcttgat cgtgggcatt ttctatcgcg gactgggaac
    12181 tgcaagactt tcgatgacga agccgatggc tattgcagag gagaggctgt cgtgactctc
    12241 atcctcaagc gtctgccaga cgcgcaatcg gacaaagacc ccatccaggc cgtcatccgt
    12301 ggcattgcca ccaatcactc ggcagaggct gatagcatca cccggccgca tgcgggcgct
    12361 caacaaaatc tgttccagca ggtcctcacc gagaccggca tcagcgcgaa cgatatttct
    12421 gtatgcgaga tgcacggcac cggcacccaa gctggagaca atggtgagac gacctcggtc
    12481 gtcgagactc ttgcacctct gaaccgatct gggtgtgcgg tgcgaccttc cgacaagaag
    12541 ctgtacattg gtagtgccaa atcgaacgtt ggtcatggtg agtctgcagc tggtgtgacc
    12601 agcctggcca aggtcttgct catgctcaag cattccaaaa tcccgcctca tataggaatc
    12661 aagacgaagc taaatcatcg attaccggac attgctgcgc gcaacaccca catcccgcgt
    12721 gctgaggtag cttggccccg acccgagaat ggcaagcgtc gtgtcttgct caacaacttc
    12781 tcggctgcag gaggcaatac gtgtcttgtg cttgaggatg cccctgaggt tgaacagttc
    12841 caagagctgg accccaggct gcatcacatc gttacacttt ccgccaagac tgcagattca
    12901 atggcttcca acctcatgaa catgattaca tggatcgacc agaattctgg ggacagcaaa
    12961 aacaccttgc ccagactgtc ttatacgacg actgcacgca gaatgcacca taaacacaga
    13021 gctgtggctg tcggtacaga tctcttgcaa atccgtacgt cgctccaaga acagcttgac
    13081 cgccgcatgg ctggtgagaa gagcgtgcct catcctccca aaggacctag ctttgtcttc
    13141 gctttcaccg gtcagggctc cgcctttgca gcaatgggtg cagatctgta ccagcatttc
    13201 gccacatttc ggtcagacat cgctcgctat gaccagattt gcgagcgcat gagcctgccc
    13261 tcgattaaag ctatgttcga ggacgaccag gctttcttga cagcctcgcc tacagtgcag
    13321 caactcacac acgtctgcct ccagatggca ttatacagat tatggaagtc gtttggcata
    13381 caagcgaaag cggtagtcgg ccacagtctg ggtgaatacg ctgcactcta cgccgccgga
    13441 gtcctctcgc aatccgatgt cctctatctg gtgggacgac gagcacaact gatggaacag
    13501 catctctcgc aaggcacaca cgccatgctg gctgttcgag cgaaagagga agccattgtt
    13561 gcagcgatag ctgggccccc tggagacgcc tacgagttct cttgccgcaa cggcgaacag
    13621 cgaaatgttc tcggaggcac cgttgaccaa atcaacgcag caaaatccgc actggagacg
    13681 aagaagatcc gttgccagta cttggataca ccaatggctt tccacacagc ccaagtcgat
    13741 ccgattctgc cagagttgtt gcaggtcgcc gccgcatgct ccattcagga acctcagatt
    13801 cccgtcattt ccccaacata cgggagagtg atcagaaatg acatacaacc agaatatttc
    13861 acacaccact gtcgtaggcc tgtcaacatg gtcgatgcgc ttgagagtgc aatcgaagaa
    13921 ggcttgctcg acaagaacac aattggtctg gagcttggcc ctgctgcggt ggtcacgcag
    13981 ttgatcaagg aagctgttgg cacatcaatg caggcattcg catctatcaa caaggacaag
    14041 gacacttggc agctcatgac acacgcactg gccaggatgt atcttgcagg tgctggcgtc
    14101 gagtggtcgc gctatcacga agatttctcc ggagcccaaa aggtgcttga gctgcccgct
    14161 tacggttgga ccttgaagaa ctactggcta caatatgtca acgactggtc tctcaggaag
    14221 ggagatccac ctacgattgt cactgcgtca aacctggagc tctctccatc gatacacaag
    14281 gtcgtgacca acacgatcaa tcccagcagc gatggcgagc ttgtcgtgga cgctgacctc
    14341 agtcgagaag atctgcatcc catggtccaa ggccaccaag tttacggtgt acctctctgc
    14401 acgccggtat gtctcctctc gttcccattt cgctcaaacg actgacttct gctagtccgt
    14461 gtatgcggat attgccatga cactcggcga gtatattcga aagatcatca agccgggcca
    14521 gatcgcgcag acggctgttg aagtagctga gatgaatatt caaagcgcac tggtggccaa
    14581 cagtacgggc aaagtgcagc tccttcgcac ctgtgccaaa ttcgacccca aggcccaaat
    14641 agcgtcatgc acattctcca ctgtcaaggt cggtcactga atccaaagac atagagtgag
    14701 ttcgatacta aaatttgact aggaggacgg caacagtgtc atcgaacagc atgccaactg
    14761 ccagatccgc ttcttcgatc ttgagaatga gaaacgtggc ctcagggacg ctgccatcgc
    14821 tgctcaagct aggatgggcg ccttgaaagc acagattggc caagatgaca atacgtaccg
    14881 cttcagcaaa ggcatgatct acaaaatgat cggtcaacta gcagacttcg acgagaagta
    14941 ccgcggtctc tgcgcaatca cgctcgacaa cgaccaaatg gaagcatctg gtaccgtgtc
    15001 attcaagggt atcccgaacg acggcaaatt tcacacgagc ccggcttatc tcgatgcatt
    15061 gtcacaattg ggcggcttcg tcatgaacgg gaacgaggga ttggacctgg agaaggaagt
    15121 gtttgtcaac catggctggg gctctatgtg tttcttcgca gctttggacc cggcaatgac
    15181 ctactacact catgtgaaga tgacccaagg caaagacaag ctgtggacag gcgatgtcct
    15241 gattttcgac ggcaagcaag cattgattgg catcgtgagg ggagtcgcat tgcaaggtgt
    15301 ccccaaacgt ctgatgcatt acatcgttac agctgccaac aagaaagctt ctggaggtac
    15361 agcgccggcc gagaagaaag tcagcacgcc tgttgcaccc acgaggccag caatccagcg
    15421 caagaatgct tcgatacctc caccatcaac ccagtcgact gtacagacca agaccaacaa
    15481 cacgccgtct gtgtcagcgc tgatagcacc ggccctcgaa attgtcagcg aagagatcgg
    15541 gatgccgatc gacgagctca aggatgatat cgacttcacg gatgccggtc tcgactcgct
    15601 tctgtcgctg gttattagca gtcggatgcg agaccaactt ggcattgagt tcgaatccgc
    15661 acaattcatg gagatcggat ctattggtgg actgaagcaa ttcttgacca agctcagccc
    15721 gccggtagca gttgccgttg ccactgctgt ggaagttgtc aaagaagaag cgctcgctgc
    15781 actggaagag cttgcaagcc ctacatccga tgagattggc gctgtctggc gggacgcgct
    15841 taagattctt acagaagaga gcgggctgac caacgacgaa ttgactgacg acgtgtcctt
    15901 caccgacgtg ggcgtcgatt cgctcatgtc gctggtcatt acgagtcgcc tgcgtgatga
    15961 gttggatatc gacttcccag accgagcgtt gtttgaagaa tgccaaacaa tatccgatct
    16021 ccgcaagaag ttctctttgc cgacggagta tttggactcc acgtcgaccg aagcaaacgc
    16081 tggtcatacg acgccccaac ttaccgattc cagctcatct tccccgtcgt cttccgtgta
    16141 cgagggtgag accccgatga ccgatctgga cgaggtattc gactcccctc cagcacagaa
    16201 gaaaccgggt ccgccaaagc aacaaattcc acctgcgtgg tcaatgtatt tgcaaggctc
    16261 acagaagcgg tcgaaggaaa tcctgttctt gtttccagac ggcgctggtg ccgccacgtc
    16321 ctatctgtct ttgccacggc tctctccaga cattggcgtc gttgccttta actcaccgtt
    16381 catgaagtaa gtcatctttg caagcttgca aggcaacaga tactaacacg aggttcctgc
    16441 agaacaccgc acaaatttgc cgatcatacg ttaccagaag tgattgcctc ctacatagag
    16501 ggcatccggg gccgacaacc acaagggcca tatcatctag gcggctggtc tgcaggcggc
    16561 atcctggcct atgccgtggc ccaagaactg atctcagccg gcgaggagat ctcgacactt
    16621 ctcctcatcg attcgccttc gcctatcaaa ggactggatc gccttccgac acgattcttc
    16681 gatcactgca cgaatgttgg actatttgga acggagttgt caagaggcag cggcggtagc
    16741 aagacccctc ctgagtggct gatgccgcac ttccgagctt ctattgagct gctgcacgac
    16801 taccacgctc ctcccatgaa gcctgggaac aagacgaaag tcatgctgat atgggctggc
    16861 gagtgtgcgt ttgacggggt gcgatatgct catttgccgc catcttcagg tgacaccgat
    16921 gaagacactg agggtatgaa gttcttgacg gagaagcgga aagatttcgg tgctacggaa
    16981 tggtcaggct tgtttcctgg caacgatgtg gacgcgaggg ttgttgaaag cgagcaccac
    17041 tttagcatga tgcgcgatgg tggtgcgcag acacttgttg agcatatgcg agatggttta
    17101 gggattgttg cctcgtgata gcatcaagat taggcgttgg aattcgatca cgatgctatg
    17161 ttttacctcg ctcagagtga cactcgaatc tcggctaccg tcgtttggac cactactaca
    17221 tcgaaacatg tgtccaagct atgcatccat tcacccttct cttgcatgat ggacatcctc
    17281 aaattcattg agtacgttgt tgggtgctcg cataacacag ggcaatagcg acgggctggt
    17341 ctcggcaaca gcgttcaccg ataccgctcg gtgaacgaca attttagaga cttgtatttc
    17401 ctcttcaccg catccacgag acagcgcctc atctcggtga tttagtcgcg gtatgcgacg
    17461 aggcattgca agcggacaca atggccgagc cggtgtgact gctagacatg gctttggtag
    17521 tcccggcttg tgaaggcata tattatgcta tattcggctc cccttctcaa cttatcagac
    17581 gtttggattg acacaaaaat ctacagatct atatcaacac aatggccagt cgaattgaag
    17641 cggatgggct tttcgagctc acggcagagc tggtctcggc ctcctcaaaa ctgaacaagt
    17701 tcctagacca gaaaggactt ccccagccat cgttcgacgc tccggcccca tcagtggctc
    17761 tcaacacaga gaacaagcca tactacgatg cgagaagcgc aatcgtagaa gctgccgagc
    17821 agatcatccg cctggtccgt ggacctcgtg atactctgct cgcattatcc ttcgagcatt
    17881 gcgctacggc atcgatgcaa gtcatcttcc ggtacaaatt cgcttctcac attccattac
    17941 atggctctac gacgtacagc aagattgccg cagcagtcgg agagggtgtg actgccgctc
    18001 ttgtcgagcg cacgatacag cattgtgctt ctttcggcct gttcgagacg attccgggcg
    18061 gatacgtcac ccacaatgct acctcatcac tgcttgtcac cgacccggat ctcgaggcct
    18121 ggatgtatct ctcagcagtc atcgcctatc cagctggcgc agccattccc aaagctgttg
    18181 aacagtacgg cgttagcatg gaagcagatg aggcaggata cggtgccagc atcggacgca
    18241 agattgcaca gttccaacgt ttccgtgagc ccgatggaaa gaaagaccac gagatgttcg
    18301 cgagagctat gcgtggtatc gcagctggag gtgcgtacga tttccgccac gcggtcgacg
    18361 gcggctaccc atggcacctc ctggccaaag gcgctggcca cctggttgtg gatgtcggtg
    18421 gcggtccagg ccatgtcgcc atggcgctcg cagagaagta cccaaccttg cgtttcgaag
    18481 tccaagattt gcctgagacc gtccaagtgg gagcaaagaa ctgcccgggg cacttgcaga
    18541 agcgtgttgc attccgcgcg cacgatttca tgactctaca gccggctcat gaagtacaag
    18601 gagacgaagg catcgcatac tttgctcgat ttatcttgca cgactggagc gacaagtacg
    18661 caacaaagat cgtacagcag ctggcgagtg gcttgaggcc acaggatcgc atcattctga
    18721 atgaggtggt cgtgcctgaa tccggacagg tgggcagaga gactcagcga agaatgcacg
    18781 atcgcgatct gctgatgttg atgaatctca atgggcggga acgcacacag agtgcgtttg
    18841 aagccatttt tgcttcagtg actcccaagc tgcgactcca gagggttcac tatccagagc
    18901 agggcgaact gtcgctcatt gaggtcactc ttgatggtgt tgagcttccc ggccacggcg
    18961 atgcagtcaa atggcactaa tggagtgcat tccaacggga ctaatggtac caatggtcac
    19021 tgaaacgttt tagggaatgt agaacctgta cttatgtagc catttcaact cgccttcatc
    19081 acccatgagc ttcttatgat ggattttgat gttccaaggt cgcagccggt agggtacgtg
    19141 catgaaaaaa aaaacctctt ccctcacgtg agcatctttc tcatcttgtt catccacgta
    19201 cactttcgcg attctgtacg gagggcgtgt gctgagcgtc gattgcattg cgaaaaattt
    19261 ctatatcgta taggcaggtg agattgggct tcatgtccat ttgctccaat ctagtgttgg
    19321 tttgtatagc tctaggataa atacgttgtt tgttgccaac aggacccaca gtcgactaca
    19381 ttcacgggca aaaatttgcc tgacgaaaga tctcacatcg gtggctgcca cttgctcttt
    19441 gctcggatgt tggcaccgaa gtagtagaat aggattggga tcgggatcat ggtgactgcg
    19501 agcaaggcaa gaatggtcgt tccccacttt acgccgattg tagcatacat cgaagtcctg
    19561 gaaaacagtc agtatagtac gaacgcaaag ttagagttgc tatgcttacg ctagaatcgg
    19621 aaagcccgca gcgaacaggc ttctcaagaa ggtgttggca gctacagcgg aattggcgta
    19681 gattttgtaa gagtcgatga tataattcag gccctgcatg ttgatcaggt gaataccgaa
    19741 gccagtaggg acacccgata atatttgagg ccagggattc atagttgcgg agcttgtcca
    19801 ggcaaagcag aacatcccag ccggcaatga cacggcgcca accatcatga gtaacagtct
    19861 cgtctcttga ggccggcctt cgttggcgtt cggtgcccat cgggaattgg ttgtgaatga
    19921 gagcagcgcc cctgccataa tgaccccaac taggatggag ataagtggta gactggcgga
    19981 tatttgatcc cagccacgct cttgaatgaa tgatgtcggg tatgccaaga agaagttata
    20041 caatagacct ttgactgaat cagtgctttt ccttctcgcc tgaactcaga taatgttgga
    20101 cttaccaaat gacacactga catacattgt catcatcaac aaaatgggct caagagccag
    20161 catgcgagct ggccggagca ggtaacgctc tgcaaaatcg ccaagactgc ttcgcgcttc
    20221 ctcagacttg gatcggtaag cccagttacg tgtcatatgg cgcatccgtt cagcacgacg
    20281 ggccagaagc agcggcgaat acgtctcggg catgaatggg aaggtacaga tagcaatgag
    20341 gaatgaggca atcgcaacaa catttgcgat ccatcgccaa ccaagcgcgc tttgcacaag
    20401 tactgatccg atcagcggtc caaggattgg tccaatagtc agaaatgcgc caactgtagg
    20461 cattgcgaaa cctcgttctc tcggtgacca tatatcggcc agagtacctg acagtatgga
    20521 cgaaggtgca gctccagtca agccctgcag atagcggaga cagaagatgg tagtcgggct
    20581 ctgtgcatcg gcaataggta gttgcaggat cgcaaaggcg agatagcccg cgatcaaagg
    20641 tcgagttcgg ccgaaggctt cgctgaaagg tctggaagtt atcagtccca gtgcctgcgc
    20701 tgcgcgacaa gaaatgtcga acttaccccc agaaaacagg tccagtcgcg aacccgacca
    20761 taaagagtga agtacagcct agcaccacag tctccgctgg caaggcgaat tctttcgcga
    20821 gaacgtgggt tgcagccccg aacaccgatg aagagaacgt tgtggacagg gcatacaatg
    20881 ccaaagacat tgtgatcacc catttgcgcc aataaggtag attctgaggg tcccctttgt
    20941 cattgtcgcc aacccagtcc actagatacg cctcactttt aatggtctca agtatttgct
    21001 cttcgaattc catagcttcg gccgtcgatt gcggtgggga agctgccccc gacgagaagg
    21061 tcacatgggg tcgcttcaat ccgtccaggt cgtcgtcagc aatagaggga gccatcgtga
    21121 gtgtgcaagt ttcgtcaaac gaaacggtcc aaggcttgaa agatcaaaag catactttgt
    21181 tcttagatgg cgcataggtc aaatttcgag ttcttccgta ggtgactagc ccctggtgca
    21241 aagttggccg gctcatatcc tggcatcgca gtcgtcgaga ctacgatcat tccgaaggct
    21301 cggtgaacat tcaccgttcg ccgtagtgtc gattggcaca ttgccttcca caaacaagct
    21361 ccgtagccac tctgacgttt ttgcatctgc cgttttgcag cgctggttgc cggcggcgag
    21421 caacttgcca aaagccgaga cgatggtggg tgacaaagag gaataggaga gaacgtagga
    21481 ttgaccaaag gcctgcgcga attcggccct cttggcatcc catcggccga aattcccgag
    21541 cgcagctcga acttcacttc agctcttgga catatcagcg atgcgctctt gtgcaccgtg
    21601 agcagattct ggcaatcttt cggcaaccag attttgaaga tagcgtccca cagagcacgg
    21661 tctcactaga ttgtgtcaaa tgtgacagag agagattgcc agatttgaag attgcatgag
    21721 ctctcctgct tcctagacaa cctccacgcc ttcgtccttc tcaggcaact ccaagtactg
    21781 cttaacgacg tcaagaactt gtgcttcata gggcgtgtgc ttgaattcga acgtctcttc
    21841 agtcttccgc acgtcaaacc tgacaccttt atttaccgtc ggcatgtgcc catcgtttgg
    21901 tagtacgcct tccgccaccg cttccgggta gtccctctgc acgaactcct tcacatcatc
    21961 ccattccgaa ccatcttctg gactgcacga aatcaggaag ctctggttcc cagcgatctt
    22021 gggattcaat gccgaaacat gacaccgagc gacatcgtcg ttgtggcatg ttagaagtgg
    22081 cttgccgacg gggttcttat ggccgagcac aatctgcatg gagtgccagt tcgatgagaa
    22141 cttgcgcagg tcctcgcgag tcgtcgccaa atcgtctcgt ccagtcacga aggatggatg
    22201 catgtggatg aggtcaaatg cgggctgctc acgcctgatc caagcttctg cgctgttgag
    22261 gcttgcgatc tttccagctt ggtaggccat catcttgtgt gcgtaaggag gctccatttc
    22321 cggaatacgc gactctgcgt ccagtggcac cttagaaggc tccgcaaaaa tggcttttgg
    22381 cgtgaaaagt gcgaccatac tggatgtgat cacgattcgt cgcacggttg cagatcgttt
    22441 tgcggcctcc agaatcccaa tgctacctct cacagcaaca cgtttgaagt cgtgttccca
    22501 atcttcggga ttgtcggagc tgacgattgg gctggcaacg tgaataatgt aggacgtgtt
    22561 ctcagcagcc tgatcgaaag cgccttcggt cacgaagtcc gtgacgatgg tggtttggaa
    22621 cccggctttc cagttcgccc ctttcgttac tgcagccaac cgcgactcca gccatcgtcc
    22681 tttggtaggg cttcgaacca cagctcgcac gttgtatcct tgatggagca gctcgacgag
    22741 tatgcggaaa ccaatgaagc cggttgcacc ggtcaagaga acccgagaat cggccat
//
