BGC0001544 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001544 (Aspergillus campestris IBT 28561)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like,T1PKS	1	27,727

BGC0001544 - Region 1 - NRPS-like,T1PKS

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Location: 1 - 27,727 nt. (total: 27,727 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 27,728
Label		BGC0001544

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001544.1	2.00	NRP, Polyketide	chlorflavonin	Aspergillus campestris IBT 28561
BGC0001068.1	0.55	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001647.1	0.50	Polyketide	lagunapyrone A, lagunapyrone B, lagunapyrone C	Streptomyces sp. MP131-18
BGC0000056.1	0.47	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001280.1	0.44	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.44	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000003.1	0.43	Polyketide	AF-toxin	Alternaria alternata
BGC0000138.1	0.39	Polyketide	rimocidin	Streptomyces diastaticus
BGC0001793.1	0.38	Polyketide	swainsonine	Chaetothyriaceae sp.
BGC0001659.1	0.38	Terpene	mangicol A	Fusarium equiseti

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001544.1	1.00	NRP, Polyketide	chlorflavonin	Aspergillus campestris IBT 28561
BGC0001068.1	0.61	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001647.1	0.58	Polyketide	lagunapyrone A, lagunapyrone B, lagunapyrone C	Streptomyces sp. MP131-18
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001280.1	0.55	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.55	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000003.1	0.54	Polyketide	AF-toxin	Alternaria alternata
BGC0000138.1	0.52	Polyketide	rimocidin	Streptomyces diastaticus
BGC0001793.1	0.51	Polyketide	swainsonine	Chaetothyriaceae sp.
BGC0001659.1	0.51	Terpene	mangicol A	Fusarium equiseti

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27727:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

P168DRAFT_323099

Search NORINE for peptide: strict or relaxed

AMP-binding (12..425): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: cilvmangsk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

PKS_AT (1199..1489): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 129.8
Methoxymalonyl-CoA: 72.5
Methylmalonyl-CoA: 72.2
inactive: 55.8
Ethylmalonyl-CoA: 34.1
Propionyl-CoA: 33.0
fatty_acid: 30.1
Acetyl-CoA: 26.1
Isobutyryl-CoA: 25.5
CHC-CoA: 24.9
2-Methylbutyryl-CoA: 16.2
trans-1,2-CPDA: 15.2
Benzoyl-CoA: 6.3
3-Methylbutyryl-CoA: 0.0