BGC0001545 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001545 (Fusarium graminearum PH-1 (Gibberella zeae PH-1))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	17,511	chrysogine	NRPS:Type I	100%

BGC0001545 - Region 1 - NRPS

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Location: 1 - 17,511 nt. (total: 17,511 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 17,512
Label		BGC0001545

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001545	1.00	NRP	chrysogine	Fusarium graminearum PH-1
BGC0001249	0.33	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900	0.33	Other	ferrichrome	Aspergillus oryzae
BGC0000348	0.30	NRP	ergovaline	Epichloe festucae var. lolii
BGC0002157	0.30	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001261	0.29	NRP	AM-toxin	Alternaria alternata
BGC0002710	0.27	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0002199	0.25	Alkaloid	nanangelenin A	Aspergillus nanangensis
BGC0000313	0.25	NRP	beauvericin	Beauveria bassiana
BGC0000457	0.25	NRP	vicibactin	Rhizobium etli CFN 42

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001545	1.00	NRP	chrysogine	Fusarium graminearum PH-1
BGC0001249	0.66	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0000348	0.64	NRP	ergovaline	Epichloe festucae var. lolii
BGC0002157	0.63	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001261	0.62	NRP	AM-toxin	Alternaria alternata
BGC0002710	0.61	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0002199	0.59	Alkaloid	nanangelenin A	Aspergillus nanangensis
BGC0000313	0.59	NRP	beauvericin	Beauveria bassiana
BGC0000457	0.59	NRP	vicibactin	Rhizobium etli CFN 42

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 17511:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

FGSG_11395

Search NORINE for peptide: strict or relaxed

AMP-binding (229..632): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVRSVGAGIK
Nearest Stachelhaus code(s):: Trp DVASVGAVVK (59% 8Å match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1309..1701): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DIGLGCMVIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)