LOCUS       BGC0001548              3455 bp    DNA     linear   BCT 18-MAY-2016
DEFINITION  Streptomyces albulus strain B-3066
            B3066_ACTTGA_L001_R1_001_(paired)_contig_20, whole genome shotgun
            sequence.
ACCESSION   BGC0001548
VERSION     BGC0001548
KEYWORDS    .
SOURCE      Streptomyces albulus
  ORGANISM  Streptomyces albulus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 02:28:48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3455
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[901:3455]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      902..3455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..3455
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..3455
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001548"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..3455
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..843
                     /locus_tag="A4V12_08800"
     CDS             1..843
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1286:Pentapeptide
                     repeat protein (Score: 72.6; E-value: 4e-22)"
                     /gene_kind="other"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_009720417.1"
                     /locus_tag="A4V12_08800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxetanocin A resistance protein"
                     /protein_id="OAL15484.1"
                     /transl_table=11
                     /translation="MTSGRTGTQTDPLRGDCANCFGLCCVALPFAASADFAVDKPAGTP
                     CANLAADFRCGIHERLRDRGFTGCTVYDCFGAGQKVSQITFGGRDWRQDPDTARRMFAA
                     FPVVRHLHELLAYLTEVLALEPASRLHDEAGRVLAETERLTLLPPEELAALDLDAHRRT
                     VGDLLSRAAELVRAGVPGARGKRKNRRGADLMGARLAGADLRGATLRGAYLIAADLTGA
                     DLRDADLLGADLRDARLAGADLTGALFLTQPQLNAARGDDRTVLPARLTRPAHWTPRQ"
     gene            complement(902..1348)
                     /locus_tag="A4V12_08805"
     CDS             complement(902..1348)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_004946594.1"
                     /locus_tag="A4V12_08805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyketide beta-ketoacyl synthase"
                     /protein_id="OAL15485.1"
                     /sec_met_domain="PF13471 (E-value: 6.8e-29, bitscore: 88.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALDIPTGVPFGRRLAARLVLVPAVLLSLLPPRRIRAVLEV
                     VRRGARPATAGRAQAARDAVCAVSLRCAGPRGCLPRSLGAALLCRLTGTWPTWCTGVSV
                     VPPFAAHAWIEAEGRPVGEPMPDDYFTRLLAVGPASPPGGAPHH"
     gene            complement(1345..1599)
                     /locus_tag="A4V12_08810"
     CDS             complement(1345..1599)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_006602540.1"
                     /locus_tag="A4V12_08810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="OAL15486.1"
                     /sec_met_domain="PF05402 (E-value: 7.1e-19, bitscore: 56.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.4e-28,
                     bitscore: 86.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALRFGTDVSTTETGYGTVLLDQRNGQYWELNPTATLIVRVLMES
                     GDETAAVEALTDAYDIDRAGAEADVAALVAELRASGLAA"
     gene            complement(1638..3455)
                     /locus_tag="A4V12_08815"
                     /pseudo=""
     CDS             complement(1638..3455)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 115.6; E-value: 4e-35)"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_003988505.1"
                     /locus_tag="A4V12_08815"
                     /note="incomplete; partial in the middle of a contig;
                     missing stop; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="asparagine synthase"
                     /pseudo=""
                     /sec_met_domain="Asn_synthase (E-value: 5.5e-51, bitscore:
                     162.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEAHESAGPGPGDAHVAVLPDLDAAAAVARFFARPGTRTLPHPS
                     GRPWLVGHWRDDEMVTARAGSTALALIGCHTLDPDALRRHAARLRDIARLDALARSLPG
                     SCHLLAALDGRLRAQGTASGLRLVFHARIEGVTVAATRADVLAAALGLAPDEEQLAVRL
                     LWPVPHPLGEAPMWRGVTAVPPGEALVVGPDGRTVRHSRWWTPPEPVRTLAAGAPLVRE
                     ALTEAVDARTRQGGVVSCDLSGGLDSTTICFLADRSPARVVASTWPGRDPADTDLQWAR
                     QAARFLPDTEHVVWDPHASPLVYTDLLDIDDLLDEPTIGVMDRSRVLHHLPAMAGRGSR
                     LHLTGIGGDHVAWCSEAYYHRLARRRPLFALRQLRGFRALWQWPLGGTLRALADSRSYR
                     AWLADAERHLHDPLPGSVDSGLGWGVPPRLFDWVTPDAARTARRALREAAAGARPLHPD
                     RGMHTDLEQIRSCTRIIRQWDRMAVGAGVPMASPFLDDRVIEACLAVRPEERVTPWAYK
                     PLLAAAMRGVVPDVCLRRTNKAAASMDAADGLREHRAELAELWADPHLARLGLVDAEVL
                     RGLARRPSAPGLRDAVLYSTIACEVWLRGL"
ORIGIN
        1 gtgacgtccg gacggaccgg cacccagacc gaccccctgc gcggggactg cgcgaactgc
       61 ttcggcctgt gctgcgtcgc cctgcccttc gccgcctccg cggatttcgc cgtcgacaag
      121 ccggcgggca ccccgtgcgc gaacctggcc gcggacttcc gctgcggcat ccacgagcgg
      181 ctgcgcgacc ggggcttcac cggctgcacg gtgtacgact gtttcggcgc cgggcagaag
      241 gtctcgcaga tcacgttcgg cggccgcgac tggcggcagg acccggacac cgcacggcgg
      301 atgttcgccg cgttcccggt cgtacggcac ctgcacgaac tcctcgcgta cctcaccgag
      361 gtcctggccc tggagcccgc gagccggctg cacgacgagg cggggcgtgt cctcgccgag
      421 accgagcggc tgacgctcct gccgcccgag gaactcgccg cgctggacct ggacgcgcac
      481 cggcggaccg tcggcgacct gttgtcgcgg gcggccgaac tggtccgggc gggcgtgccg
      541 ggcgccaggg gcaagcggaa gaaccgccgc ggcgccgacc tcatgggcgc ccggctggcc
      601 ggcgcggacc tgcgcggcgc gacgctgcgc ggcgcgtacc tcatcgcggc cgacctcacc
      661 ggcgccgacc tgcgggacgc cgatctgctc ggggccgacc tccgcgacgc gcggctcgcg
      721 ggcgccgacc tgaccggggc gctgttcctc acccagccgc agctcaacgc ggcacgcggc
      781 gacgaccgta ccgtgctgcc cgcccggctc acccgccccg cgcactggac gccgcggcag
      841 taggccccgg cccgggcccg gtgacgcggg ccgccgccgg gtgccgagcg gtccggagcg
      901 gtcagtggtg cggggcgcct ccgggcggtg acgcggggcc cacggcgagc agacgtgtga
      961 agtagtcgtc gggcatcggc tcaccgacgg ggcggccctc cgcctcgatc caggcgtgcg
     1021 cggcgaaggg cggcaccacg ctcacccccg tgcaccaggt gggccaggtg ccggtcagcc
     1081 ggcacagcag tgcggcgccc agcgagcggg gcaggcaccc gcgcggtccg gcgcaccgca
     1141 ggctcaccgc gcacacggcg tcgcgggctg cctgcgcccg gcctgcggtg gcggggcgcg
     1201 ccccgcgccg cacgacctcc agcacggccc ggatgcggcg cggcggcagg agcgacagca
     1261 ggacggcggg caccagcacc agccgggcgg cgaggcggcg gccgaagggc acgccggtgg
     1321 ggatgtccag ggcgctgggc gtggtcatgc ggccagcccg gaggcgcgca gctcggccac
     1381 cagcgcggcg acgtccgcct cggcgccggc ccggtcgatg tcgtacgcgt cggtgagcgc
     1441 ctcgacggcc gcggtctcgt cgccactctc catcagcacg cgcacgatca gcgtggcggt
     1501 ggggttcagc tcccagtact gcccgttgcg ctggtcgagg aggacggtgc cgtatccggt
     1561 ctccgtggtg gagacgtcgg ttccgaagcg cagtgccatg gtgacttccc ttccttcgag
     1621 agtgccgagc gcgccgcgag gccgcgcagc cagacctcgc aggcgatcgt cgagtagagg
     1681 acggcgtcgc gcagtccggg tgcggacggc cgccgggcga ggccgcgcag cacctcggcg
     1741 tccaccaggc cgagccgtgc gaggtgaggg tccgcccaca gttcggccag ctccgcccgg
     1801 tgctcccgca gtccgtcggc cgcgtccatg gacgcggcgg ccttgttggt gcggcgcagg
     1861 cagacgtccg gcacgacgcc gcgcatggcg gcggcgagca ggggtttgta cgcccagggg
     1921 gtgacgcgct cctcggggcg gaccgcgagg caggcctcga tcacccggtc gtcgaggaac
     1981 ggcgaggcca tcggcacccc ggcgccgacc gccatccgat cccactgccg gatgatccgg
     2041 gtgcaggagc ggatctgctc caggtcggtg tgcatgcccc ggtccgggtg cagcggtcgc
     2101 gcgcccgccg ccgcctcccg gagggcccgc cgcgccgtcc gggccgcgtc gggggtcacc
     2161 cagtcgaaga ggcgtggggg cacgccccag ccgaggccgc tgtcgaccga gccgggcagc
     2221 gggtcgtgca ggtgccgttc cgcgtcggcg agccaggccc ggtaggagcg ggagtcggcc
     2281 agggcgcgga gggtcccgcc gagcggccac tgccacaggg cgcggaaccc gcgcagctgc
     2341 cgaagggcga acagcggtcg ccggcgcgcc agtcggtggt agtacgcctc ggagcaccag
     2401 gcgacgtggt cgccgccgat gccggtcagg tggaggcggc tgccgcgccc ggccatggcc
     2461 ggcaggtggt gcaggacccg cgagcggtcc atgacgccga tcgtgggttc gtccagcagg
     2521 tcgtcgatgt cgagcaggtc ggtgtagacc agcggtgaag cgtggggatc ccagacgacg
     2581 tgctcggtgt ccggcaggaa ccgggcggcc tgccgggccc actggaggtc ggtgtcggcc
     2641 gggtcgcgcc cgggccaggt gctggccacc acacgggcgg gcgagcggtc ggcgaggaag
     2701 cagatggtgg tggagtccag cccgccggac aggtcgcaac tgaccacgcc accctggcgg
     2761 gtgcgggcgt cgaccgcctc ggtcagggct tcgcggacca gcggcgcccc ggcggcgagc
     2821 gtccggaccg gttccggggg cgtccaccac cgcgagtggc ggacggtacg cccgtccggg
     2881 ccgacgacga gcgcctcgcc gggcggtacg gcggtgacac cgcgccacat cggcgcctcc
     2941 ccgagcgggt ggggcacggg ccacaacagc cgtacggcca gctgctcctc gtccggggcg
     3001 aggcccagcg ccgcggcgag cacgtcggcg cgggtggcgg ccaccgtcac gccctcgatc
     3061 cgggcgtgga acaccagccg caggccggac gcggtgccct gcgccctgag ccggccgtcg
     3121 agcgcggcca ggaggtggca actgccgggg aggctacggg ccagggcgtc gagccgggcg
     3181 atgtcccgca accgcgcggc gtggcggcgc agcgcgtccg ggtcgagggt gtggcagccg
     3241 atgagggcga gcgcggtgga gcccgcgcgg gcggtcacca tctcgtcgtc ccgccagtgg
     3301 ccgaccagcc aggggcggcc cgaggggtgc ggcagcgtgc gcgtaccggg gcgggcgaag
     3361 aaccgggcca cggcggccgc ggcgtcgagg tcgggaagga ccgcgacgtg cgcgtcaccg
     3421 gggcccgggc ccgcactttc gtgcgcttca gtcat
//
