Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001556.1:
Cluster 1NRP / Polyketide121510

BGC0001556, combamide biosynthetic gene cluster from Streptomyces sp. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: combamide

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Modular Type I

Gene cluster description

combamide (BGC0001556). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank MH167394. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Liu Y et al. (2018) Targeted Discovery and Combinatorial Biosynthesis of Polycyclic Tetramate Macrolactam Combamides A-E. Org Lett 20(12):3504-3508. doi: 10.1021/acs.orglett.8b01285. Epub