BGC0001560: cryptomaldamide biosynthetic gene cluster from Moorea producens JHB
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Location: 1 - 28,792 nt. (total: 28,792 nt).
This entry is originally from NCBI GenBank KY315923.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001560
Short description cryptomaldamide biosynthetic gene cluster from Moorea producens JHB
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
KY315923.1
via
Compounds
  • cryptomaldamide
Species Moorea producens JHB [taxonomy]
References
Chemical products information
cryptomaldamide Evidence:
Copy SMILES
C18H33N5O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARO38310.1
 1 - 276 (+) transposase
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    • ARO38311.1
    • cpmA
    		 1153 - 2247 (+) amidinotransferase
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      • ARO38312.1
      		 3341 - 3505 (-) hypothetical protein
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        • ARO38313.1
        		 3978 - 4112 (+) hypothetical protein
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          • ARO38314.1
          		 4282 - 4500 (+) hypothetical protein
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            • ARO38315.1
            		 5045 - 5203 (+) hypothetical protein
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              • ARO38316.1
              		 5417 - 5779 (+) transposase
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                • ARO38317.1
                • cpmB
                		 6185 - 25504 (+) nonribosomal peptide synthetase
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                  • ARO38318.1
                  		 25590 - 26078 (+) transcriptional regulator MerR family
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                    • ARO38319.1
                    		 26212 - 27045 (+) transposase
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                      • ARO38320.1
                      		 27066 - 27305 (+) transposase
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                        • ARO38321.1
                        		 27299 - 28792 (+) MATE efflux family protein
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                          Biosynthesis information

                          Biosynthetic modules

                          Name
                          Unk01
                          Type
                          nrps-type1
                          Genes
                          cpmB
                          Substrates
                          cysteine (evidence: Structure-based inference, Mass spectrometry, Sequence-based prediction)
                          Integrated Monomers
                          Domains
                          adenylation
                          Name
                          Unk02
                          Type
                          nrps-type1
                          Genes
                          cpmB
                          Substrates
                          valine (evidence: Structure-based inference, Mass spectrometry, Sequence-based prediction)
                          Integrated Monomers
                          Domains
                          adenylation
                          Name
                          Unk03
                          Type
                          nrps-type1
                          Genes
                          cpmB
                          Substrates
                          valine (evidence: Structure-based inference, Mass spectrometry, Sequence-based prediction)
                          Integrated Monomers
                          Domains
                          adenylation
                          Annotation changelog

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Added NRP substrate specificities
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2019-10-16
                          Migrated from v1.4
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2019-10-16
                          Updated compound(s) information (NPAtlas curation)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2018-08-06
                          Submitted
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Detailed domain annotation
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