BGC0001561: curacomycin biosynthetic gene cluster from Streptomyces curacoi
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1,237 - 18,814 nt. (total: 17,578 nt).
This entry is originally from NCBI GenBank LMWJ01000028.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001561
Short description curacomycin biosynthetic gene cluster from Streptomyces curacoi
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: partial
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LMWJ01000028.1
1237 - 18814
via
Compounds
  • curacomycin
Species Streptomyces curacoi [taxonomy]
References
Chemical products information
curacomycin Evidence: NMR [1]
Copy SMILES
C37H56Cl1N9O8
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQI70_32520
  • KUM69037.1
 1237 - 2025 (-) hypothetical protein
    copy AA seq
    copy Nt seq
    • AQI70_32525
    • KUM69038.1
    		 2768 - 3121 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • AQI70_32530
      • KUM69039.1
      		 3090 - 3869 (-) hypothetical protein
        copy AA seq
        copy Nt seq
        • AQI70_32535
        • KUM69040.1
        		 3875 - 5053 (-) hypothetical protein
          copy AA seq
          copy Nt seq
          • AQI70_32540
          • KUM69041.1
          		 5428 - 5652 (+) hypothetical protein
            copy AA seq
            copy Nt seq
            • AQI70_32545
            • KUM69042.1
            		 5679 - 6107 (+) hypothetical protein
              copy AA seq
              copy Nt seq
              • AQI70_32550
              • KUM69043.1
              		 6430 - 7101 (-) LuxR family transcriptional regulator
                copy AA seq
                copy Nt seq
                • AQI70_32555
                • KUM69047.1
                		 7089 - 8300 (-) histidine kinase
                  copy AA seq
                  copy Nt seq
                  • AQI70_32560
                  • KUM69048.1
                  		 8524 - 9336 (+) ABC transporter ATP-binding protein
                    copy AA seq
                    copy Nt seq
                    • AQI70_32565
                    • KUM69044.1
                    		 9333 - 12086 (+) ABC transporter permease
                      copy AA seq
                      copy Nt seq
                      • AQI70_32570
                      • KUM69045.1
                      		 12194 - 12601 (+) hypothetical protein
                        copy AA seq
                        copy Nt seq
                        • AQI70_32575
                        • KUM69046.1
                        		 12911 - 14191 (+) hypothetical protein
                          copy AA seq
                          copy Nt seq
                          • AQI70_32580
                          		 14276 - 18814 (+)
                            copy AA seq
                            copy Nt seq
                            Biosynthesis information
                            Annotation changelog

                            Entry version: next

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2024-08-01
                            MIBiG v4 annotathon
                            • (ID: 4ZBJCWV5NZUBDJXCSIV4TKIA)
                            • (ID: JXNPUXPAL6VYCS4XEXVRJDGK)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 3

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-09-15
                            Corrected publication
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            2022-09-15
                            Marked as incomplete, other half of BGC0001562
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 2

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2019-10-16
                            Migrated from v1.4
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2018-08-06
                            Submitted
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            Detailed domain annotation
                            Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                            A domain glossary is available here, and an explanation of the visualisation is available here.
                            Selected features only
                            Show module domains
                            Similar known gene clusters from MIBiG 4.0
                            Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                            Click on reference genes to show details of similarities to genes within the current region.
                            Click on an accession to open that entry in the MiBIG database.