BGC0001562: curacomycin biosynthetic gene cluster from Streptomyces curacoi
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 314,041 - 333,483 nt. (total: 19,443 nt).
This entry is originally from NCBI GenBank LMWJ01000003.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001562
Short description curacomycin biosynthetic gene cluster from Streptomyces curacoi
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: incomplete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: LMWJ01000003.1
Compounds
  • curacomycin
Species Streptomyces curacoi [taxonomy]
References
Chemical products information
curacomycin
Copy SMILES
C37H56Cl1N9O8
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQI70_05450
  • KUM80505.1
 314041 - 315708 (-) 2-isopropylmalate synthase
copy AA seq
copy Nt seq
  • AQI70_05455
  • KUM80506.1
 315866 - 316714 (-) amidinotransferase
copy AA seq
copy Nt seq
  • AQI70_05460
  • KUM80535.1
 316778 - 317251 (-) oxidase
copy AA seq
copy Nt seq
  • AQI70_05465
  • KUM80507.1
 317426 - 318931 (-) tryptophan halogenase
copy AA seq
copy Nt seq
  • AQI70_05470
  • KUM80508.1
 319076 - 319579 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AQI70_05475
  • KUM80509.1
 319576 - 320694 (-) branched chain amino acid aminotransferase
copy AA seq
copy Nt seq
  • AQI70_05480
  • KUM80510.1
 320743 - 321129 (-) ketosteroid isomerase
copy AA seq
copy Nt seq
  • AQI70_05485
  • KUM80511.1
 321126 - 322121 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AQI70_05490
  • KUM80512.1
 322180 - 322389 (-) protein mbtH
copy AA seq
copy Nt seq
  • AQI70_05495
  • KUM80513.1
 322442 - 330325 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AQI70_05500
  • KUM80514.1
 330412 - 333483 (-) hypothetical protein
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected publication
  • Marked as incomplete, other half of BGC0001561
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.