BGC0001562: curacomycin biosynthetic gene cluster from Streptomyces curacoi
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Location: 314,041 - 333,483 nt. (total: 19,443 nt).
This entry is originally from NCBI GenBank LMWJ01000003.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001562
Short description curacomycin biosynthetic gene cluster from Streptomyces curacoi
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: partial
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LMWJ01000003.1
314041 - 333483
via
Compounds
  • curacomycin
Species Streptomyces curacoi [taxonomy]
References
Chemical products information
curacomycin Evidence:
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C37H56Cl1N9O8
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQI70_05450
  • KUM80505.1
 314041 - 315708 (-) 2-isopropylmalate synthase
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    • AQI70_05455
    • KUM80506.1
    		 315866 - 316714 (-) amidinotransferase
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      • AQI70_05460
      • KUM80535.1
      		 316778 - 317251 (-) oxidase
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        • AQI70_05465
        • KUM80507.1
        		 317426 - 318931 (-) tryptophan halogenase
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          • AQI70_05470
          • KUM80508.1
          		 319076 - 319579 (-) hypothetical protein
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            • AQI70_05475
            • KUM80509.1
            		 319576 - 320694 (-) branched chain amino acid aminotransferase
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              • AQI70_05480
              • KUM80510.1
              		 320743 - 321129 (-) ketosteroid isomerase
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                • AQI70_05485
                • KUM80511.1
                		 321126 - 322121 (-) hypothetical protein
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                  • AQI70_05490
                  • KUM80512.1
                  		 322180 - 322389 (-) protein mbtH
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                    • AQI70_05495
                    • KUM80513.1
                    		 322442 - 330325 (-) hypothetical protein
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                      • AQI70_05500
                      • KUM80514.1
                      		 330412 - 333483 (-) hypothetical protein
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                        Biosynthesis information
                        Annotation changelog

                        Entry version: 4

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-10-07
                        Update chemical activity to schema version 2.11
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Corrected publication
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Marked as incomplete, other half of BGC0001561
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Updated bioactivity data
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2018-08-06
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
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