BGC0001564: cusperin biosynthetic gene cluster from Cuspidothrix issatschenkoi CHARLIE-1
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Location: 1 - 54,398 nt. (total: 54,398 nt).
This entry is originally from NCBI GenBank MG518226.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001564
Short description cusperin biosynthetic gene cluster from Cuspidothrix issatschenkoi CHARLIE-1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
MG518226.1
via
Compounds
  • cusperin
Species Cuspidothrix issatschenkoi CHARLIE-1 [taxonomy]
References
Chemical products information
cusperin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AVR48533.1
  • cusA
 1 - 15069 (+) CusA
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    • AVR48534.1
    • cusB
    		 15075 - 16202 (+) CusB
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      • AVR48535.1
      • cusC
      		 16202 - 44983 (+) CusC
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        • AVR48532.1
        • cusD
        		 45016 - 46947 (+) CusD
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          • AVR48536.1
          • cusE
          		 46996 - 48420 (-) CusE
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            • AVR48537.1
            • cusF
            		 48777 - 49634 (+) CusF
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              • AVR48538.1
              • cusG
              		 49674 - 49934 (+) CusG
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                • AVR48539.1
                • cusH
                		 49912 - 51150 (+) CusH
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                  • AVR48540.1
                  • cusI
                  		 51188 - 52426 (+) CusI
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                    • AVR48541.1
                    • cusJ
                    		 52414 - 53202 (+) CusJ
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                      • AVR48542.1
                      • cusK
                      		 53199 - 54398 (+) CusK
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                        Biosynthesis information

                        Biosynthetic modules

                        Name
                        Unk01
                        Type
                        nrps-type1
                        Genes
                        cusC
                        Substrates
                        glycine (evidence: Structure-based inference, Mass spectrometry, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk02
                        Type
                        nrps-type1
                        Genes
                        cusC
                        Substrates
                        proline (evidence: Structure-based inference, Mass spectrometry, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk03
                        Type
                        nrps-type1
                        Genes
                        cusC
                        Substrates
                        glycine (evidence: Structure-based inference, Mass spectrometry, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Annotation changelog

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Added NRP substrate specificities
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2018-08-06
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
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