BGC0001565: cyclosporin C biosynthetic gene cluster from Beauveria felina
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Location: 1 - 90,396 nt. (total: 90,396 nt).
This entry is originally from NCBI GenBank MF716954.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001565
Short description cyclosporin C biosynthetic gene cluster from Beauveria felina
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: MF716954.1
Compounds
  • cyclosporin C
Species Beauveria felina [taxonomy]
References
Chemical products information
cyclosporin C
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C62H111N11O13
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATQ39424.1
 172 - 2859 (-) hypothetical protein
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  • ATQ39425.1
 3732 - 5050 (-) bZIP transcription factor
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  • ATQ39426.1
 6927 - 8405 (+) F-box domain protein
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  • ATQ39428.1
  • cycC
 9189 - 55043 (-) cyclosporin C synthetase
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  • ATQ39427.1
 55629 - 56862 (+) alanine racemase
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  • ATQ39429.1
 61295 - 65554 (-) ABC transporter
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  • ATQ39430.1
 66945 - 68201 (+) esterase-like protein
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  • ATQ39431.1
 68327 - 70087 (-) cytochrome b2-like protein
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  • ATQ39432.1
 70770 - 79609 (-) PKS
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  • ATQ39433.1
 80999 - 82103 (+) hypothetical protein
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  • ATQ39434.1
 83899 - 85773 (+) cytochrome P450
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  • ATQ39435.1
 86278 - 87537 (-) aminotransferase
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  • ATQ39436.1
 89054 - 90079 (-) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
cycC
Module ?
Specificity: D-alanine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: E-butenyl-4R-methylthreonine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: threonine / 2-aminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
  • Homology
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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