BGC0001570: deimino-antipain biosynthetic gene cluster from Streptomyces albulus
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Location: 224,545 - 240,028 nt. (total: 15,484 nt).
This entry is originally from NCBI GenBank LWBU01000384.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001570
Short description deimino-antipain biosynthetic gene cluster from Streptomyces albulus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LWBU01000384.1
224545 - 240028
via
Compounds
  • deimino-antipain
Species Streptomyces albulus [taxonomy]
References
Chemical products information
deimino-antipain Evidence: NMR [2]
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C27H43N9O7
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • A4V12_31625
  • OAL11431.1
 224545 - 225639 (+) hydrolase
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    • A4V12_31630
    • OAL11432.1
    		 225971 - 227287 (+) MFS transporter
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      • A4V12_31635
      • OAL11433.1
      		 227373 - 228791 (+) non-ribosomal peptide synthetase
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        • A4V12_31640
        • OAL11434.1
        		 228784 - 228990 (-) hypothetical protein
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          • A4V12_31645
          • OAL11435.1
          		 229019 - 232378 (+) non-ribosomal peptide synthetase
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            • A4V12_31650
            • OAL11436.1
            		 232378 - 234315 (+) hypothetical protein
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              • A4V12_31655
              • OAL11475.1
              		 234317 - 236197 (+) non-ribosomal peptide synthetase module
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                • A4V12_31660
                • OAL11476.1
                		 236334 - 239276 (+) non-ribosomal peptide synthetase/polyketide synthase
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                  • A4V12_31665
                  • OAL11437.1
                  		 239552 - 240028 (+) regulator
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                    Biosynthesis information

                    Biosynthetic modules

                    Name
                    Unk01
                    Type
                    nrps-type1
                    Genes
                    A4V12_31645
                    Substrates
                    arginine (evidence: )
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk02
                    Type
                    nrps-type1
                    Genes
                    A4V12_31650
                    Substrates
                    phenylalanine (evidence: )
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk03
                    Type
                    nrps-type1
                    Genes
                    A4V12_31655
                    Substrates
                    valine (evidence: )
                    Integrated Monomers
                    Domains
                    adenylation
                    Annotation changelog

                    Entry version: next

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2024-04-23
                    MIBiG v4 annotathon
                    • (ID: 5SRAIADCX5E626OGO7LYHFZD)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 4

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Update chemical activity to schema version 2.11
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Updated bioactivity data
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Added NRP substrate specificities
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2018-08-06
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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