BGC0001578 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001578 (Talaromyces stipitatus ATCC 10500)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	31,150

BGC0001578 - Region 1 - T1PKS

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Location: 1 - 31,150 nt. (total: 31,150 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 31,151
Label		BGC0001578

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001578.1	0.62	Polyketide	duclauxin	Talaromyces stipitatus ATCC 10500
BGC0001969.1	0.29	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001858.1	0.29	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.28	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000675.1	0.27	Terpene	(+)-T-muurolol	Streptomyces clavuligerus ATCC 27064
BGC0000107.1	0.24	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001265.1	0.23	Polyketide	melanin	Bipolaris oryzae
BGC0001909.1	0.23	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000003.1	0.23	Polyketide	AF-toxin	Alternaria alternata
BGC0001258.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001578.1	0.85	Polyketide	duclauxin	Talaromyces stipitatus ATCC 10500
BGC0001969.1	0.63	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001858.1	0.63	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.62	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000675.1	0.60	Terpene	(+)-T-muurolol	Streptomyces clavuligerus ATCC 27064
BGC0000107.1	0.57	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001265.1	0.56	Polyketide	melanin	Bipolaris oryzae
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000003.1	0.56	Polyketide	AF-toxin	Alternaria alternata
BGC0001258.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis

Similar known gene clusters

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 31150:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TSTA_083310

PKS_AT (924..1227): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
Methoxymalonyl-CoA: 46.1
Methylmalonyl-CoA: 45.7
inactive: 38.8
Ethylmalonyl-CoA: 26.2
Isobutyryl-CoA: 25.8
Propionyl-CoA: 25.6
fatty_acid: 22.8
2-Methylbutyryl-CoA: 21.8
CHC-CoA: 17.3
Acetyl-CoA: 17.0
Benzoyl-CoA: 15.6
3-Methylbutyryl-CoA: 11.2
trans-1,2-CPDA: 0.0