BGC0001582: ecumicin biosynthetic gene cluster from Nonomuraea sp. MJM5123
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Location: 1 - 74,009 nt. (total: 74,009 nt).
This entry is originally from NCBI GenBank KJ144825.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001582
Short description ecumicin biosynthetic gene cluster from Nonomuraea sp. MJM5123
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KJ144825.1
Compounds
  • ecumicin
Species Nonomuraea sp. MJM5123 [taxonomy]
References
Chemical products information
ecumicin
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C83H134N14O17
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIW58896.1
 9374 - 10717 (+) cytochrome P450 monooxygenase
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  • AIW58897.1
 10723 - 11829 (-) hypothetical protein
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  • AIW58898.1
 11855 - 12856 (-) O-methyltransferase
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  • AIW58899.1
 13040 - 13870 (-) putative ABC transporter
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  • AIW58900.1
 13867 - 14742 (-) hypothetical protein
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  • AIW58901.1
 14826 - 15527 (-) hypothetical protein
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  • AIW58902.1
 15596 - 16891 (-) hypothetical protein
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  • AIW58895.1
 16933 - 18021 (-) putative ATPase AAA
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  • AIW58894.1
 18118 - 18354 (-) hypothetical protein
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  • AIW58893.1
 18452 - 18670 (-) MbtH-like protein
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  • AIW58892.1
 18667 - 64446 (-) non-ribosomal peptide synthetase
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  • AIW58891.1
 65017 - 67695 (+) putative serine/threonine protein kinase
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  • AIW58890.1
 67679 - 67879 (-) hypothetical protein
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  • AIW58889.1
 67997 - 68434 (-) hypothetical protein
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  • AIW58888.1
 68723 - 68926 (+) hypothetical protein
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  • AIW58887.1
 69086 - 69889 (+) LmbU and CloE-like protein
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  • AIW58884.1
 69991 - 70326 (+) hypothetical protein
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  • AIW58885.1
 70607 - 72433 (-) hypothetical protein
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  • AIW58886.1
 72433 - 73464 (-) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
AIW58892.1
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: allo-isoleucine / isoleucine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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