BGC0001583 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001583 (Escovopsis weberi)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	21,067	secalonic acids	Polyketide	18%

BGC0001583 - Region 1 - T1PKS

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Location: 1 - 21,067 nt. (total: 21,067 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 21,068
Label		BGC0001583

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001583.1	0.67	Polyketide	emodin	Escovopsis weberi
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001265.1	0.23	Polyketide	melanin	Bipolaris oryzae
BGC0001257.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001284.1	0.23	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001258.1	0.22	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000107.1	0.22	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001882.1	0.19	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0000121.1	0.19	Polyketide	RES-1214-2	Pestalotiopsis fici
BGC0000046.1	0.19	Polyketide	depudecin	Alternaria brassicicola

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001583.1	0.87	Polyketide	emodin	Escovopsis weberi
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001265.1	0.56	Polyketide	melanin	Bipolaris oryzae
BGC0001257.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001284.1	0.56	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001258.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000107.1	0.55	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001882.1	0.51	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0000121.1	0.51	Polyketide	RES-1214-2	Pestalotiopsis fici
BGC0000046.1	0.51	Polyketide	depudecin	Alternaria brassicicola

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 21067:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

EmoG

PKS_AT (874..1165): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 62.5%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 94.6
inactive: 67.7
Methylmalonyl-CoA: 52.2
Methoxymalonyl-CoA: 43.6
Propionyl-CoA: 32.1
Benzoyl-CoA: 19.2
2-Methylbutyryl-CoA: 16.6
Isobutyryl-CoA: 16.3
CHC-CoA: 12.7
3-Methylbutyryl-CoA: 12.6
Ethylmalonyl-CoA: 12.1
trans-1,2-CPDA: 9.2
fatty_acid: 0.0
Acetyl-CoA: 0.0