BGC0001590: formicamycins A-M biosynthetic gene cluster from Streptomyces sp. KY5
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Location: 1 - 43,083 nt. (total: 43,083 nt).
This entry is originally from NCBI GenBank KX859301.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001590
Short description formicamycins A-M biosynthetic gene cluster from Streptomyces sp. KY5
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KX859301.1
Compounds
  • formicamycins A-M
Species Streptomyces sp. KY5 [taxonomy]
References
Chemical products information
formicamycins A-M
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • orf4
  • AQP25545.1
 11 - 931 (+) NAD-dependent epimerase/dehydratase
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  • orf3
  • AQP25546.1
 1334 - 2344 (+) marR family transcriptional regulator
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  • orf2
  • AQP25547.1
 3530 - 4129 (+) hypothetical protein
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  • orf1
  • AQP25548.1
 4048 - 4560 (-) transposase
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  • forQ
  • AQP25549.1
 5320 - 6588 (+) decarboxylase
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  • forP
  • AQP25550.1
 6601 - 7254 (+) metallo-beta-lactamase
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  • forO
  • AQP25551.1
 7285 - 8064 (+) exodeoxyribonuclease III
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  • forN
  • AQP25552.1
 8121 - 9893 (-) acylhydrolase
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  • forM
  • AQP25553.1
 10140 - 10925 (+) methyltransferase
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  • forL
  • AQP25554.1
 10960 - 11301 (+) PKS cyclase
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  • forK
  • AQP25555.1
 11309 - 12745 (+) Na+/H+ exchanger
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  • forJ
  • AQP25556.1
 12823 - 13272 (+) marR family transcriptional regulator
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  • forI
  • AQP25557.1
 13294 - 14661 (-) ACC biotin carboxylase
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  • forH
  • AQP25558.1
 14643 - 16466 (-) ACC carboxyl transferase
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  • forG
  • AQP25559.1
 16976 - 18067 (+) sensor histidine kinase
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  • forF
  • AQP25560.1
 18075 - 18734 (+) luxR family response regulator
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  • forE
  • AQP25561.1
 18738 - 19253 (-) ACC biotin carboxy carrier protein
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  • forD
  • AQP25562.1
 19250 - 19711 (-) PKS cyclase/dehydratase
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  • forC
  • AQP25563.1
 19714 - 20004 (-) PKS ACP protein
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  • forB
  • AQP25564.1
 20001 - 21248 (-) KSB protein
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  • forA
  • AQP25565.1
 21245 - 22507 (-) KSA protein
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  • forR
  • AQP25566.1
 22504 - 22899 (-) cupin (cyclase/monooxygenase)
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  • forS
  • AQP25567.1
 22927 - 23247 (-) monooxygenase/cyclase
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  • forT
  • AQP25568.1
 23244 - 24272 (-) O-methyltransferase
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  • forU
  • AQP25569.1
 24393 - 24752 (+) monooxygenase/cyclase
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  • forV
  • AQP25570.1
 24745 - 26037 (+) halogenase
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  • forW
  • AQP25571.1
 26034 - 27059 (+) O-methyltransferase
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  • forX
  • AQP25572.1
 27069 - 28784 (+) monooxygenase
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  • forY
  • AQP25573.1
 28963 - 29910 (+) oxidoreductase
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  • forZ
  • AQP25574.1
 29867 - 30385 (-) marR family transcriptional regulator
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  • forAA
  • AQP25575.1
 30474 - 32015 (+) MFS family transporter
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  • forBB
  • AQP25576.1
 32025 - 32687 (-) LuxR family response regulator
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  • forCC
  • AQP25577.1
 32684 - 33937 (-) sensor histidine kinase
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  • orf6
  • AQP25578.1
 34060 - 35025 (+) ABC transporter
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  • orf7
  • AQP25579.1
 35022 - 35876 (+) ABC transporter permease
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  • orf8
  • AQP25580.1
 36034 - 37623 (+) glutamate synthase
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  • orf9
  • AQP25581.1
 37613 - 38113 (-) hypothetical protein
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  • orf10
  • AQP25582.1
 38113 - 38724 (-) hypothetical protein
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  • orf11
  • AQP25583.1
 39031 - 39525 (+) hypothetical protein
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  • orf12
  • AQP25584.1
 39640 - 40383 (+) glutamate ABC transporter
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  • orf13
  • AQP25585.1
 40394 - 41326 (+) ABC transporter substrate binding protein
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  • orf14
  • AQP25586.1
 41336 - 41980 (+) ABC transporter permease
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  • orf15
  • AQP25587.1
 41977 - 42846 (+) ABC transporter permease
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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