BGC0001593 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001593 (Streptomyces ficellus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	29,585	Ficellomycin	NRPS:Type I	100%

BGC0001593 - Region 1 - NRPS

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Location: 1 - 29,585 nt. (total: 29,585 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 29,586
Label		BGC0001593

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001593	0.98	NRP	ficellomycin	Streptomyces ficellus
BGC0002075	0.32	NRP, Alkaloid	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001464	0.26	Other	tetrabromopyrrole	Pseudoalteromonas sp. PS5
BGC0001463	0.26	Other	2,3,4,5-tetrabromopyrrole	Pseudoalteromonas piscicida
BGC0002359	0.26	NRP	dudomycin A	Streptomyces albus subsp. chlorinus
BGC0002528	0.25	NRP	aminochelin, azotochelin, protochelin	Azotobacter vinelandii CA
BGC0002689	0.25	NRP	2,3-dihydroxybenzoylserine	Stenotrophomonas maltophilia K279a
BGC0001890	0.25	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001132	0.25	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833	0.25	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001593	1.00	NRP	ficellomycin	Streptomyces ficellus
BGC0002075	0.65	NRP, Alkaloid	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0002359	0.60	NRP	dudomycin A	Streptomyces albus subsp. chlorinus
BGC0002689	0.60	NRP	2,3-dihydroxybenzoylserine	Stenotrophomonas maltophilia K279a
BGC0001464	0.59	Other	tetrabromopyrrole	Pseudoalteromonas sp. PS5
BGC0001463	0.59	Other	2,3,4,5-tetrabromopyrrole	Pseudoalteromonas piscicida
BGC0002528	0.59	NRP	aminochelin, azotochelin, protochelin	Azotobacter vinelandii CA
BGC0001890	0.58	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001132	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 38 - 29585:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ARF06222.1

AMP-binding (510..903): X

nrpys: dn-dohHep

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVFDFGGVTK
Nearest Stachelhaus code(s):: dn-dohHep DVFDFGGVTK (97% 8Å match)
Stachelhaus code match:: 100% (strong)