BGC0001593: ficellomycin biosynthetic gene cluster from Streptomyces ficellus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 11,780 - 41,364 nt. (total: 29,585 nt).
This entry is originally from NCBI GenBank KY454693.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001593
Short description ficellomycin biosynthetic gene cluster from Streptomyces ficellus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KY454693.1
Compounds
  • ficellomycin
Species Streptomyces ficellus [taxonomy]
References
Chemical products information
ficellomycin
Copy SMILES
C13H24N6O3
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARF06202.1
 11781 - 12674 (-) inner membrane amino-acid ABC transporter permease protein
copy AA seq
copy Nt seq
  • ARF06203.1
 12674 - 13624 (-) AtrA protein
copy AA seq
copy Nt seq
  • ARF06204.1
 13856 - 14614 (-) short-chain dehydrogenase/reductase SDR
copy AA seq
copy Nt seq
  • ARF06205.1
 14611 - 15930 (-) major facilitator superfamily transporter
copy AA seq
copy Nt seq
  • ARF06206.1
 15927 - 17225 (-) carboxylase
copy AA seq
copy Nt seq
  • ARF06207.1
 17478 - 18686 (-) ornithine--oxo-acid transaminase
copy AA seq
copy Nt seq
  • ARF06208.1
 18787 - 20112 (-) sulfate adenylyltransferase subunit 1
copy AA seq
copy Nt seq
  • ARF06209.1
 20114 - 21079 (-) sulfate adenylyltransferase subunit 2
copy AA seq
copy Nt seq
  • ARF06210.1
 21076 - 21639 (-) adenylsulfate kinase
copy AA seq
copy Nt seq
  • ARF06211.1
 21636 - 22508 (-) AmCP-L-glutamate kinase
copy AA seq
copy Nt seq
  • ARF06212.1
 22531 - 23556 (-) N-acetyl-gamma-glutamyl-phosphate reductase
copy AA seq
copy Nt seq
  • ARF06213.1
 23594 - 23767 (-) lysine biosynthesis protein LysW
copy AA seq
copy Nt seq
  • ARF06214.1
 23781 - 24731 (-) transketolase
copy AA seq
copy Nt seq
  • ARF06215.1
 24728 - 25570 (-) transketolase
copy AA seq
copy Nt seq
  • ARF06216.1
 25567 - 26862 (-) glutamine--scyllo-inositol transaminase
copy AA seq
copy Nt seq
  • ARF06217.1
 26907 - 27977 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ARF06218.1
 27974 - 28567 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ARF06219.1
 28807 - 29541 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ARF06220.1
 29822 - 30700 (+) lysine biosynthesis enzyme LysX
copy AA seq
copy Nt seq
  • ARF06221.1
 30697 - 31821 (+) N-acetyl-ornithine/N-acetyl-lysine deacetylase
copy AA seq
copy Nt seq
  • ARF06222.1
 31818 - 35969 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • ARF06223.1
 35980 - 37134 (+) dehydrogenase
copy AA seq
copy Nt seq
  • ARF06224.1
 37136 - 38260 (+) dehydrogenase
copy AA seq
copy Nt seq
  • ARF06225.1
 38333 - 39049 (-) LuxR family transcriptional regulator
copy AA seq
copy Nt seq
  • ARF06226.1
 39268 - 39408 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ARF06227.1
 40324 - 41364 (+) scyllo-inosamine-4-phosphate amidinotransferase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Refined reference coordinates
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.