BGC0001603: gentamicin biosynthetic gene cluster from Micromonospora echinospora
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 46,458 nt. (total: 46,458 nt).
This entry is originally from NCBI GenBank KY971520.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001603
Short description gentamicin biosynthetic gene cluster from Micromonospora echinospora
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
KY971520.1
via
Compounds
  • gentamicin
Species Micromonospora echinospora [taxonomy]
References
Chemical products information
gentamicin Evidence:
Copy SMILES
C19H38N4O10
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARV75698.1
1 - 540 (+) hypothetical protein
    copy AA seq
    copy Nt seq
    • ARV75699.1
    631 - 1710 (+) putative tryptophanyl-tRNA synthatase
      copy AA seq
      copy Nt seq
      • ARV75700.1
      1777 - 2934 (+) putative queuine tRNA-ribosyltransferase
        copy AA seq
        copy Nt seq
        • ARV75701.1
        2966 - 3859 (+) GmrB
          copy AA seq
          copy Nt seq
          • ARV75702.1
          3873 - 5126 (-) C-6' aminotransferase
            copy AA seq
            copy Nt seq
            • ARV75703.1
            5158 - 6681 (-) 6'-hydroxyl dehydrogenase
              copy AA seq
              copy Nt seq
              • ARV75704.1
              6854 - 7663 (-) putative dehydrogenase
                copy AA seq
                copy Nt seq
                • ARV75705.1
                7678 - 8853 (-) 2-deoxystreptamine glycosyltransferase
                  copy AA seq
                  copy Nt seq
                  • ARV75706.1
                  8962 - 9786 (-) GmrA
                    copy AA seq
                    copy Nt seq
                    • ARV75707.1
                    10081 - 11343 (+) 1-keto-2-deoxy-scyllo-inosamine aminotransferase
                      copy AA seq
                      copy Nt seq
                      • ARV75708.1
                      11478 - 12671 (+) 2-deoxy-scyllo-inosose synthase
                        copy AA seq
                        copy Nt seq
                        • ARV75709.1
                        12706 - 13689 (+) 3''-hydroxyl dehydrogenase
                          copy AA seq
                          copy Nt seq
                          • ARV75710.1
                          13778 - 14950 (+) paromamine glycosyltransferase
                            copy AA seq
                            copy Nt seq
                            • ARV75711.1
                            15027 - 16931 (+) C-4'' methyltransferase
                              copy AA seq
                              copy Nt seq
                              • ARV75712.1
                              17015 - 18187 (+) C-3'' aminotransferase
                                copy AA seq
                                copy Nt seq
                                • ARV75713.1
                                18195 - 18566 (+) hypothetical protein
                                  copy AA seq
                                  copy Nt seq
                                  • ARV75714.1
                                  18659 - 19996 (-) C-6' aminotransferase
                                    copy AA seq
                                    copy Nt seq
                                    • ARV75715.1
                                    20052 - 20858 (-) C-3' phosphorylase
                                      copy AA seq
                                      copy Nt seq
                                      • ARV75716.1
                                      20896 - 22248 (-) C-6' aminotransferase
                                        copy AA seq
                                        copy Nt seq
                                        • ARV75717.1
                                        22884 - 24800 (-) C-6' methyltransferase
                                          copy AA seq
                                          copy Nt seq
                                          • ARV75718.1
                                          25050 - 26294 (+) 6'-epimerase, C-6' aminotransferase
                                            copy AA seq
                                            copy Nt seq
                                            • ARV75719.1
                                            26385 - 26897 (-) hypothetical protein
                                              copy AA seq
                                              copy Nt seq
                                              • ARV75720.1
                                              26952 - 27887 (-) hypothetical protein
                                                copy AA seq
                                                copy Nt seq
                                                • ARV75721.1
                                                28082 - 29488 (-) hypothetical protein
                                                  copy AA seq
                                                  copy Nt seq
                                                  • ARV75722.1
                                                  29781 - 30803 (-) 2-deoxy-scyllo-inosose dehydrogenase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • ARV75723.1
                                                    31284 - 32798 (+) putative membrane antiporter
                                                      copy AA seq
                                                      copy Nt seq
                                                      • ARV75724.1
                                                      32920 - 33657 (+) hypothetical protein
                                                        copy AA seq
                                                        copy Nt seq
                                                        • ARV75725.1
                                                        33663 - 34301 (+) hypothetical protein
                                                          copy AA seq
                                                          copy Nt seq
                                                          • ARV75726.1
                                                          34301 - 34654 (+) hypothetical protein
                                                            copy AA seq
                                                            copy Nt seq
                                                            • ARV75727.1
                                                            34733 - 38149 (-) putative exporter
                                                              copy AA seq
                                                              copy Nt seq
                                                              • ARV75728.1
                                                              38146 - 40083 (-) putative exporter
                                                                copy AA seq
                                                                copy Nt seq
                                                                • ARV75729.1
                                                                40609 - 41487 (-) putative methyltransferase
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • ARV75730.1
                                                                  41899 - 42660 (+) putative deacetylase
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • ARV75731.1
                                                                    42657 - 43622 (+) N-3'' methyltransferase
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • ARV75732.1
                                                                      43809 - 44333 (-) hypothetical protein
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        • ARV75733.1
                                                                        44450 - 45766 (-) putative two-component system histidine kinase
                                                                          copy AA seq
                                                                          copy Nt seq
                                                                          • ARV75734.1
                                                                          45763 - 46458 (-) putative two-component system response regulator
                                                                            copy AA seq
                                                                            copy Nt seq
                                                                            Biosynthesis information
                                                                            Annotation changelog

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            Migrated from v1.4
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            Submitted
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            Similar known gene clusters from MIBiG 4.0
                                                                            Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                            Click on reference genes to show details of similarities to genes within the current region.
                                                                            Click on an accession to open that entry in the MiBIG database.