BGC0001607: gilvusmycin biosynthetic gene cluster from Streptomyces sp. NRRL B-1347
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 32,187 - 60,425 nt. (total: 28,239 nt).
This entry is originally from NCBI GenBank NZ_JOJM01000053.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001607
Short description gilvusmycin biosynthetic gene cluster from Streptomyces sp. NRRL B-1347
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: NZ_JOJM01000053.1
Compounds
  • gilvusmycin
Species Streptomyces sp. NRRL B-1347 [taxonomy]
References
Chemical products information
gilvusmycin
Copy SMILES
C38H34N6O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • IG74_RS0132870
  • WP_030684641.1
 32187 - 33056 (-) arylamine N-acetyltransferase
copy AA seq
copy Nt seq
  • IG74_RS0132875
  • WP_030684642.1
 33105 - 33500 (-) pentapeptide repeat-containing protein
copy AA seq
copy Nt seq
  • IG74_RS0132880
  • WP_030684643.1
 33504 - 34553 (-) DUF4872 domain-containing protein
copy AA seq
copy Nt seq
  • IG74_RS0132885
  • WP_030684644.1
 34612 - 36111 (-) B12-binding domain-containing radical SAM protein
copy AA seq
copy Nt seq
  • IG74_RS0132890
  • WP_078869212.1
 36119 - 37021 (-) carbon-nitrogen hydrolase family protein
copy AA seq
copy Nt seq
  • IG74_RS0132895
  • WP_030684646.1
 37021 - 37725 (-) class I SAM-dependent methyltransferase
copy AA seq
copy Nt seq
  • IG74_RS0132900
  • WP_030684647.1
 37715 - 39088 (-) coproporphyrinogen III oxidase family protein
copy AA seq
copy Nt seq
  • IG74_RS0132905
  • WP_030684648.1
 39085 - 40062 (-) ABC transporter ATP-binding protein
copy AA seq
copy Nt seq
  • IG74_RS0132910
  • WP_234334526.1
 40055 - 40789 (-) ABC transporter permease
copy AA seq
copy Nt seq
  • IG74_RS0132915
  • WP_030684650.1
 40849 - 41703 (-) carbon-nitrogen hydrolase family protein
copy AA seq
copy Nt seq
  • IG74_RS0132920
  • WP_030684651.1
  • mfnA
 41747 - 42928 (-) tyrosine decarboxylase MfnA
copy AA seq
copy Nt seq
  • IG74_RS0132925
  • WP_030684655.1
 42930 - 43745 (-) carbon-nitrogen hydrolase family protein
copy AA seq
copy Nt seq
  • IG74_RS0132930
  • WP_030684657.1
 43742 - 44707 (-) carbon-nitrogen hydrolase family protein
copy AA seq
copy Nt seq
  • IG74_RS0132935
  • WP_234334527.1
 44778 - 45908 (-) AMP-binding protein
copy AA seq
copy Nt seq
  • IG74_RS0132940
  • WP_030684660.1
 45911 - 48967 (-) flavin reductase
copy AA seq
copy Nt seq
  • IG74_RS0132945
  • WP_234334528.1
 48957 - 50465 (-) 4-hydroxyphenylacetate 3-hydroxylase
copy AA seq
copy Nt seq
  • IG74_RS0132950
  • WP_030684662.1
 50477 - 51958 (-) hypothetical protein
copy AA seq
copy Nt seq
  • IG74_RS0132955
  • WP_037826444.1
 51966 - 52214 (-) ferredoxin
copy AA seq
copy Nt seq
  • IG74_RS0132960
  • WP_030684664.1
 52218 - 53585 (-) AMP-binding protein
copy AA seq
copy Nt seq
  • IG74_RS0132965
  • WP_030684665.1
 53582 - 54568 (-) BtrH N-terminal domain-containing protein
copy AA seq
copy Nt seq
  • IG74_RS0132970
  • WP_030684666.1
 54555 - 55232 (-) hypothetical protein
copy AA seq
copy Nt seq
  • IG74_RS0132975
  • WP_030684667.1
 55232 - 55918 (-) class I SAM-dependent methyltransferase
copy AA seq
copy Nt seq
  • IG74_RS0132980
  • WP_051855854.1
 55911 - 57974 (-) molybdopterin-dependent oxidoreductase
copy AA seq
copy Nt seq
  • IG74_RS0132985
  • WP_030684669.1
 58028 - 59014 (-) BtrH N-terminal domain-containing protein
copy AA seq
copy Nt seq
  • IG74_RS0132990
  • WP_030684670.1
 59154 - 60425 (-) TrpB-like pyridoxal phosphate-dependent enzyme
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.