LOCUS       BGC0001610             17634 bp    DNA     linear   BCT 28-MAR-2017
DEFINITION  Streptomyces ahygroscopicus subsp. wuzhouensis strain S91 gougerotin
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0001610
VERSION     BGC0001610
KEYWORDS    .
SOURCE      Streptomyces ahygroscopicus subsp. wuzhouensis
  ORGANISM  Streptomyces ahygroscopicus subsp. wuzhouensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:54:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17634
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..17634
                     /collection_date="1988"
                     /country="China: Wuzhou, Guangxi"
                     /db_xref="taxon:387850"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces ahygroscopicus subsp. wuzhouensis"
                     /strain="S91"
                     /sub_species="wuzhouensis"
     misc_feature    1..17634
                     /note="gougerotin biosynthetic gene cluster"
     subregion       1..17634
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001610"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17634
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(411..1130)
                     /gene="ggtA"
     CDS             complement(411..1130)
                     /codon_start=1
                     /gene="ggtA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 64.8; E-value:
                     1.4e-19)"
                     /gene_kind="biosynthetic-additional"
                     /product="Methyltransferase domain family"
                     /protein_id="ARA90604.1"
                     /transl_table=11
                     /translation="MTPAQWEALLYDWHNTHRLRRQRDDTPYWTRLTEPHESVLVLGAG
                     TGRVAGALARSAERRVTAVDLSRERLARIPRTPGLHPVCGDMRRLPLQGPHSAAVIPYS
                     TLQLLLTPEDRERALTETARVLAPGGSVHIDVSESFDSRTETDWQLSLAETCPEAGGPV
                     EEWERSRPHADHVAIEKQFRRAGRVLTEVTERWVYHRALDLAEVLARTGFELLGIDRGY
                     GRDSSPHRLVYHARRRH"
     gene            1992..3323
                     /gene="ggtB"
     CDS             1992..3323
                     /codon_start=1
                     /gene="ggtB"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 80.7; E-value: 1.7e-24)"
                     /gene_kind="transport"
                     /product="hypothetical protein"
                     /protein_id="ARA90605.1"
                     /transl_table=11
                     /translation="MGHASVRTRSRSEIWQGFEATERREVGTVIVSTLQSQSTSALLLL
                     LLSLLALRVTGSPASAPLVVAVGALPALLLVRAVRFVNQLVDHRWVMLLSDAGALVVAV
                     TLWQLVRAGGVHAWQIYAGMFLFAAFGAFYLPAMRGWVAGQTTGLEQLTWLNAMLAVAT
                     QAAVVVGWALGGVLASSIGIEGSLGLCALSYAVGLVLQFVVFVVINGASFRKPAGAPGT
                     GASGTVEPHAAAADRASATTGVWRDVFSPRRLGLFTAALLLMELTHTLGFSMFVPLLTG
                     GAADRSWIAGTANACFALAAMISGVLVSGGALGQWTRARAPQVVLVGFCVQIVFGLSVA
                     HPVWAIGLYAVVGLLSGGDAALQSEVQDRWRPAGSSQAFAVFGAVQGPAQLVGSLAVAA
                     LLTCLSVGTVYLGTVVVLGLGSGLVLMLARSRAEAPPPRVEAPV"
     gene            3398..4207
                     /gene="ggtC"
     CDS             3398..4207
                     /codon_start=1
                     /gene="ggtC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100:3-hydroxyisobutyrate dehydrogenase (Score: 156;
                     E-value: 2.3e-47)"
                     /gene_kind="biosynthetic-additional"
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="ARA90606.1"
                     /transl_table=11
                     /translation="MANLALYGLGEMGADIARCLVSRGVALHAYDPVSDVTLAAGNFHR
                     CSTAAEAARAAAVHLVVVKRPDDVRALLFGADGLCAAAPAGSHVVLHTTLTPQTVRELA
                     EEVRRQGHVLLDAALSRRNGLIREGSLSLFVGGTAEEVAAVGPVLDRYADNVVHAGPTG
                     AGMTVKLCNNWLLYSNRHAALQALGTGRALGVDPDVLRGALASSTGSSWALAHYSDLDE
                     AIVTGQGAPAVVRDRTTSELHMARDMAAANGQVPTSLQETFALLDAM"
     gene            4262..5173
                     /gene="ggtD"
     CDS             4262..5173
                     /codon_start=1
                     /gene="ggtD"
                     /product="hypothetical protein"
                     /protein_id="ARA90607.1"
                     /transl_table=11
                     /translation="MHTDIVSPDELDKAVAGLPVQVWNAPTAAELYGQTLNLVCRTRGG
                     RTAGAWVVPLDDDGTAARRPFRLLPYASPWVDPELHPVDRHRAVLSMTQALMDRVESAE
                     IPMDPRFGEAAALAEAGAELLCRHTRVLELHADRDPRTGYVATARNHIRAAAREHTVRT
                     APLDAFDFSRAVVGQPPDAVAARRRSGLRVGGVEPALCLAATDPDGTCRGQVFVLLCDG
                     AAVLMHSWFDRAGARGVPSLLVDEAIAWAGRQPGTDVFDFEGSVLPGVDRFMTGFGARA
                     CAYPQLRWRRSTEPGAGAGEFG"
     gene            5170..6288
                     /gene="ggtE"
     CDS             5170..6288
                     /codon_start=1
                     /gene="ggtE"
                     /product="conserved hypothetical protein"
                     /protein_id="ARA90608.1"
                     /transl_table=11
                     /translation="MTATDRPTEPHPGTDPPRAAPAARHRPAPARAAPPPGPVHDLRIV
                     DLDALTPAQEGAWTTAYRRHGTRLQQSPGYARAVRAAGHRVVVALAPDGIAAFTDEGAV
                     LTAVCADEPVLTEHGQAERLARLVTAVHRATGASVYLPLVAAAHAESCARAGCTVWRRP
                     PNSLIDWSRDGADLWERALARGSSQLRRKRRLVERDGLTLRPGTSGAGAFAHVLAVDDR
                     SWKARQGQSMRLRGGQDALYGRLVGTGEVTAALLLDGERPVAFRLDARVGDRLASLKWS
                     YDEDYRRYSPGLYLLTEGLRQEWAGRGVRTVDLHGSPDALKDLLHSERVPRADVWCGAA
                     DRAALRARERADLDARVARAHEAGKGLRHAFD"
     gene            6293..7210
                     /gene="ggtF"
     CDS             6293..7210
                     /codon_start=1
                     /gene="ggtF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     145.7; E-value: 3.3e-44)"
                     /gene_kind="biosynthetic-additional"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase"
                     /protein_id="ARA90609.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.2e-38,
                     bitscore: 123.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDAAVRDLLDRWGQPAAAFCASGGAALEAALEVLEVGAGAEVVV
                     PDVGCHSVAAAVVRVGAVPVFVGVGEGLTLHPPDVAAACSARTRAVIAVHQYGLPCDVP
                     GIVAAVPRGVAVIEDVAQTWGSTTRGVPAGSTGTLTVTSFGPSKPVALGAGGALLGPAD
                     LVSGAVARGDTSDRHRPRPPSPARFPAPLYPLLPAAVAEADRQLASRRAAVERFTGGDL
                     ARHFRLPGLLPGSSAGWTRVPLYPARSATPHHLAQLTDALGAAQRMHPRPPSALPMFRG
                     RDTRVVTGTRRPVEPLLVKIGRPS"
     gene            7207..8367
                     /gene="ggtG"
     CDS             7207..8367
                     /codon_start=1
                     /gene="ggtG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     217.1; E-value: 6.6e-66)"
                     /gene_kind="biosynthetic-additional"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase"
                     /protein_id="ARA90610.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.4e-67,
                     bitscore: 218.4, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVINPHQFFDLSREDQQSLTHFRATLADGQLFRYVEGDRESANT
                     LIERHFAGYFRKEAATAVANGTVGLRLALRALGIGPGDRVLVSAYSFIACAMAVSAVGA
                     VPVPMDMDTALTPDTAALETPDEPVAAVMVVHVQGHAVPAGRLRELCDRLGVPLIEDVC
                     QALGAASADGRAGELADVAVTSFQQSKQISSGEGGLVAGGAEVVERVYRMADLGAVRHD
                     GGLPDWDDERALVGDNLRMTELQAALVMDQALTLHQTLARQRGLRSSLREQLGADTPVL
                     DSSRPEGDAASHTLFVARSTADAAEFCTGLAARGVLARVVWKKTYPEYGLFRRVLPSAP
                     HPWPKKAEALAPRILSVPTSKYLTDAAVSQVAEAVVAHRHHLVQER"
     gene            8376..9542
                     /gene="ggtH"
     CDS             8376..9542
                     /codon_start=1
                     /gene="ggtH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101:phosphoglycerate mutase (Score: 95.2; E-value:
                     6.5e-29)"
                     /gene_kind="biosynthetic-additional"
                     /product="phosphoglycerate mutase"
                     /protein_id="ARA90611.1"
                     /transl_table=11
                     /translation="MNRIALLLRGLPGSGKTTTAALLRDSLVPAVRISNDSVRYMARPR
                     DFSDFTLVASELGCLDLALSYLDSGFTPVIDGVFEDVDFLAAQELRFQRKGMRLVTITL
                     DGTLTDLLDRNNARDPLARMDEDRVRELHQQFRPAGLLLGIHDKQPEEVADDVLDLLEL
                     TAQEAGTEPEATENVDVLFLRHGAPDYPSDTYPDPYAMGLSARGRDEARSARGAVERFA
                     PDAVYASDFLRARETATLVTAALDVEVQQEAALRERVFHGFAGVDLDDVRRRLGPEADR
                     VLTGNSDLCTVDGEESYEQARDRVLEFFATLAARHPGRRVLVVGHGGPHHWLLERALGA
                     DLRGVRALRWETGHFSRFRIAPDGVSVDFVNRSPEDVARSPQPAKEAP"
     gene            9539..10732
                     /gene="ggtI"
     CDS             9539..10732
                     /codon_start=1
                     /gene="ggtI"
                     /product="hypothetical protein"
                     /protein_id="ARA90612.1"
                     /transl_table=11
                     /translation="MTLRSPLVGGRARVAVVATPFGFGPSSKAYSIGQVLARDHHLDVA
                     YYGTDSALDFFAAQPDAPARPLDDPPPGQDPPALRSADAVVNVLAPELIGTDRLAARTY
                     YVDSLGFMWTAADVPPDSPLHRVRAYLAQDLFGSVAHLARLGLRDVIPVSGIVARPPAA
                     PPTVPAPAGPPGGTAARGPGRPRVLVQLGGLGNPAGHTSGRVYLALVERLLAAVRDDSA
                     VEMTAAMNHANGAFTLRAGVPVRQLSAADFHTALGRCDVVLSSPGMTTLVEVSRAGRPY
                     IPLPPQNWSQVLICRHLSARSAHDLWPFLTAPYDGIAEGAPEAAKAVAVQEVNRRLGRD
                     DGYAARYARLARHAVGNPETPDLGAPFDGAHEVAAVVAADLAARRSAVEPTTEATAS"
     gene            10729..11469
                     /gene="ggtJ"
     CDS             10729..11469
                     /codon_start=1
                     /gene="ggtJ"
                     /product="conserved hypothetical protein"
                     /protein_id="ARA90613.1"
                     /transl_table=11
                     /translation="MTEPTTARTRSALLTTLHSLAGEVDGAREWSRTSRTMAPARVATV
                     FGSARAERDEPAYQMARELGAALAARRWTTVTGGGPGIMQAVRDGSGTTLSRAVRIEIP
                     GEVPDTVLDEDRSLTVGTFALRKLLLTHDIDALFVFPGGVGTFDELFEVLVHHDTDRLD
                     RFPVVLVQPEGTGLWQAFVQFVQAHLVDAGLASPTVVKELVVAESVEAALAAVGAHPPA
                     TVPQPGTATAPDATADLGTERRTA"
     gene            11466..12413
                     /gene="ggtK"
     CDS             11466..12413
                     /codon_start=1
                     /gene="ggtK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 67.8; E-value: 1.9e-20)"
                     /gene_kind="biosynthetic-additional"
                     /product="glycosyltransferase"
                     /protein_id="ARA90614.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-29,
                     bitscore: 93.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHARPPATEHRPVDVSVIIPAYNACATLEACLLSLTHQRPQGK
                     GSFEVLVIDDGSTDGTGPMVDSFASRLDLRYVHEPRTPASGRARARNIGLALATGSLVV
                     TLDADQVVGPDFLAEHLRAHGTADDLLVVGRRHQLGEGTFDLARLARGFSLGALPEVVR
                     GDEREPVLAALGGELSDLRTAWHYLWTCNASVRRDRLAAVGGFDEEFHGWGLEDAELGY
                     RLVQDGVRMRYSTRAAVYHEHRSPVSASMYREWRANLAHFARKHPAPVVRLQEMFAPAI
                     DPAAPAAEAWVDTAVRFEHRARALAGVPQPAHHG"
     gene            12524..13813
                     /gene="ggtL"
     CDS             12524..13813
                     /codon_start=1
                     /gene="ggtL"
                     /product="conserved hypothetical protein"
                     /protein_id="ARA90615.1"
                     /transl_table=11
                     /translation="MYLPTNRPFEAAFRSVAAEVAALPEAARQQVTMLVVDDCPPPVSR
                     ANRQVAEAAAATAGVPVHVLGADGWTRFVHDLLATAALPPAERTVAEGALCKPTGSYGA
                     GPNKAALVAAYLGARTLHRRDSDQVTHVDPASGASPLRIEAELLDGGDAAGSKGAYCVG
                     SSLTGRPTRDRRDLLDRSEEFVDRIDALSRLSPAETRVARPAAPARPEEVVAHGGVPAH
                     RDHTGVVEMGIAALRRVHEWIPEMPAVGVLGSDYFQKGLLYQLELPVWHHDLTADHHYE
                     PWRAEQSSAAHLGWYARAELRYAVLRKHWNAFNEALMTQRDLLLPDGQHFDSAAYADFL
                     LDTVERGAERTAAIPSAFVEIYREAAAAASGDVRSRLDVRVAALEEAADTTGQYVADAV
                     REFAALTRSWPALVAAAGRLGVDGDLGRYA"
     gene            13913..15700
                     /gene="ggtM"
     CDS             13913..15700
                     /codon_start=1
                     /gene="ggtM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 316.6; E-value: 5.7e-96)"
                     /gene_kind="biosynthetic-additional"
                     /product="asparagine synthetase"
                     /protein_id="ARA90616.1"
                     /sec_met_domain="GATase_7 (E-value: 4.6e-31, bitscore:
                     97.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6.5e-48, bitscore:
                     154.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIGGILLKRRPSLDHRAMAVPLGASLAHRGRDGTGAFSDDWIS
                     LHSARHAVIAVDDARQPLFDCERALVMVGNGEVLNYRELSHRLPADRRRRMPPGDLQVA
                     LELCAERGTAAFEDLRGPFALAVWDSTAHELTLVRDRLGERPLYYYDSPDLFAFASELR
                     CLTACLRGETLRLDPANALAFLGLGRLPGDRTLYQDVRSVPAGGVLRIAPGAAGPRAAA
                     PLTPVSGLRAAPADETEIGQLIDQAHRRALVADRPVAVGFSGGIDSSAVLKAALEHAEP
                     AAAVTVFSARCPDEDENLRRARALARKFGVDLHEVPFRIPSLDATADLLNDTLDAPAAE
                     PLVLHNDALHRAAREHSAVLLGGHGADEVFGGYVRYAALRADAVDATTEEWMAMSLWER
                     WNRTAGWHKFVTDFGSDAVAPRTAALGDVLDRPFPYSSAEHRDPVLFGQALDLFRLMTY
                     DNFRATDENGIARGVEVRSPFFDIDLVAGVFSLPAERRIRPDAPKHLLRGVFRGTPLAG
                     EFTERKVGFDDHFSYSDWMTDNWPDFSAAIVDGPLTDLGILRDGALADLEKFDWRLLWR
                     LFSLSTWLEREGRPPVAGN"
     gene            complement(15742..16782)
                     /gene="ggtN"
     CDS             complement(15742..16782)
                     /NRPS_PKS="Domain: PKS_ER (17-245). E-value: 9.9e-12.
                     Score: 36.4. Matches aSDomain:
                     nrpspksdomains_ggtN_PKS_ER.1"
                     /codon_start=1
                     /gene="ggtN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 278.6; E-value:
                     9.9e-85)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxidoreductase"
                     /protein_id="ARA90617.1"
                     /sec_met_domain="ADH_N (E-value: 1.6e-32, bitscore: 101.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.3e-22, bitscore:
                     70.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALQYRTIGAPPEVVHVPDPTPGPGQVLLKVTAAGVCHSDFAVM
                     NRPAEGFPYPLPLTLGHEGVGTVAALGPGVTAVQEGDAVAVYGPWGCGTCAKCAEGKEN
                     YCLRADELGIRPPGLGAPGAIAEYLVVDDPRHLVPLGGLDPVAAVPLTDAGLTPYHAIK
                     RSLPKLTPGSTAVVIGAGGLGHVAIQLLRALTPARVVALDVSDDKLRLAREMGAHEAVR
                     SDSGAADAVRELTGGIGAQAVFDFVGAAPTVATAAAVAAIEADVSLVGIGGAALPVGFG
                     QLPFEVSVSAPYWGSRGELLEVLALARSGAVSVHTETFSLDDAPLAYERLHAGLIDGRA
                     VILPNG"
     aSDomain        complement(16048..16731)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ggtN_PKS_ER.1"
                     /evalue="9.90E-12"
                     /label="ggtN_PKS_ER.1"
                     /locus_tag="ggtN"
                     /protein_end="245"
                     /protein_start="17"
                     /score="36.4"
                     /tool="antismash"
                     /translation="VPDPTPGPGQVLLKVTAAGVCHSDFAVMNRPAEGFPYPLPLTLGH
                     EGVGTVAALGPGVTAVQEGDAVAVYGPWGCGTCAKCAEGKENYCLRADELGIRPPGLGA
                     PGAIAEYLVVDDPRHLVPLGGLDPVAAVPLTDAGLTPYHAIKRSLPKLTPGSTAVVIGA
                     GGLGHVAIQLLRALTPARVVALDVSDDKLRLAREMGAHEAVRSDSGAADAVRELTGGIG
                     AQAVFD"
     gene            complement(16866..17543)
                     /gene="ggtR"
     CDS             complement(16866..17543)
                     /codon_start=1
                     /gene="ggtR"
                     /gene_functions="regulatory (smcogs) SMCOG1215:TetR family
                     transcriptional regulator (Score: 154.7; E-value: 5.3e-47)"
                     /gene_kind="regulatory"
                     /product="putative TetR-family transcriptional regulator"
                     /protein_id="ARA90618.1"
                     /transl_table=11
                     /translation="MTVPEPSPDAAGAPAEDRRRRRERRTRRALATAALDLILQRGLAD
                     TTVEAIAERADVTRRTFSRHFAGKEDAALDFVRGDGDRINALLRIRPAAEPPLLAYRRA
                     VGAWLADEQSPGWHLQPKTRRLLALVDREPALFAAYERIRVDAHRESIRILAARLGTDE
                     HDMRPAVVVEASAGVLSAALRVWAHAADAGEPPANDLAALVEGAYDALAHEAAAGGRPT
                     DFP"
ORIGIN
        1 tctccgaccg tccggtgacg tccgggtcga cccgccgggg tcggcccgga cgtcctcgtt
       61 ccggcgtgct ccggtcgagc cccgcctacc ggcccgccag gaacgcgtcg aacgtccgcg
      121 gtgcacgccc ggtcaggtcc tgcaccgtcg acgtcaccct gaggcttcat ccgtttcgat
      181 ggctgggcgg atggaggtgg ccccggcctc gtcgggcggg cactccgctc cggagttcgc
      241 cggaactgcg ggtgggtgat tgccggttcg ccttcgcgtg gccgtgtggg gtgtggccgc
      301 gcaacacggc aagcattccg cgaggcacga gccaaaggtg ggggaggggc gctgagaagg
      361 gatgcgtcgt ggcggaggcg tgaaaggccg acgggcgtcg gtgcaggggg tcagtgcctt
      421 cgtcgggcgt ggtagacgag ccggtggggg gagctgtccc ggccgtatcc ccggtcgatt
      481 cccaggagtt cgaaacccgt gcgggcgaga acttcggcga ggtcgagggc gcggtggtag
      541 acccagcgtt ccgtcacctc ggtgaggacc cgaccggccc ggcggaattg cttctcgatg
      601 gccacgtggt cggcgtgcgg gcggctacgc tcccattctt ccaccggccc gccggcctcc
      661 gggcaggtct cggcgagact cagctgccag tcggtttcgg tacgggagtc aaaactctcg
      721 ctgacgtcga tgtggaccga accgcccggt gcgaggacgc gggcggtttc cgtcagggcc
      781 cgttcccggt cctcgggcgt caagagcaac tgcagcgtcg aataggggat gacggcggct
      841 gagtgcggtc cttggagcgg aagcctgcgc atgtccccgc agaccgggtg cagaccggga
      901 gtgcggggaa tgcgcgcgag ccgttcccgg ctgaggtcca cggcggtcac ccggcgctcc
      961 gcgctccggg ccagggcgcc cgccacgcgg ccggtgccgg ctccgaggac cagcacggac
     1021 tcgtgcggct cggtcaggcg ggtccagtag ggcgtgtcgt cgcgttgccg gcgcagtcgg
     1081 tgggtgttgt gccagtcgta gagcagggcc tcccactggg cgggtgtcac ggtgccgggc
     1141 tcctcgtggt gtggggcggt cggtgggggc gccgtccgga cgggcggacc ggtgcgcggg
     1201 cgagagctcc cgcgacgtcg ggtcggggtg tgtgtccgct gggtcgtcgt ccggtcccgc
     1261 gccggcctgc tggggtgccg gcggcatggg acgggggccg ggaaaagtcg gcgtcatgct
     1321 acccaccggc ctttgcgcta cccgccgccc tttacggctc cggcgtacgc cgagggaaat
     1381 cagccagtgc cgggacgcct ttttattggt cgccgaggtc ggtttcgaag tccttggtgg
     1441 gacgcatcaa ggggtgccgt acgaacctcc gaaatttttc ctccggttcg ggaaggcgcg
     1501 atatctccgc ccttctcgtg agcgtatgaa tatccggtca tgggttgccc tcgggggcat
     1561 tctgacctga ttcgatcgtc ctggtgcgcc ggaggggcgc cgttgaggtg gccgcgaccg
     1621 gccgtgaatc cggcttctcg acgaagtgtc acggtggctt tacgcgggtg tcgtccggag
     1681 ttcttcgggc cggcaattca aggcggaggg cgcgcggggc gggaacccgc ggcggtggca
     1741 cggcattgtt tccgatggtg tgatgagtgg gggtccggat gccggcgttt cagccaaaac
     1801 ccttggtgcg gactggactt ggttgaccgt ttccgagaaa tcatgcttgg gttttcggga
     1861 atcgctgcat gtctgtttct ccgtgccgtg accgaagggg tgttggcgtc ctggacggcc
     1921 tgctgccgtt aagcgtcccg ccgtgcagcg ctgcgcatcg aaaagaaatc ggaattgggg
     1981 aggtgggttg agtgggacac gcgtcggtac gcacccgttc ccgatccgag atctggcaag
     2041 ggttcgaagc caccgaacgg cgcgaggtgg gcacggtcat cgtgtcgacg ttgcagagcc
     2101 agagcacctc cgccctgctg ctcctcctgc tctccctgct cgcgctgcgg gtgacgggtt
     2161 cgccggcgag tgcgcccctg gtcgtggcgg tcggcgcgct gcccgcgctg ctgctcgtcc
     2221 gggccgtccg gttcgtcaac caactcgtcg accaccgctg ggtgatgctg ctgtccgacg
     2281 ccggcgcctt ggtggtcgcc gtgacgctct ggcagctggt gcgcgccggc ggcgtgcacg
     2341 cctggcagat ctacgccggc atgttcctct tcgccgcctt cggggccttc taccttcccg
     2401 cgatgcgcgg ctgggtcgcc ggccagacca ccggcctgga gcagttgacc tggctcaacg
     2461 cgatgctggc cgtcgccacc caggcggccg tggtggtcgg ttgggccctc ggcggagtgc
     2521 tggcgtcgtc gatcggcatc gaggggtcgc tggggctgtg cgccctgtcg tacgcggtcg
     2581 gcctggtgtt gcagttcgtg gtgttcgtgg tgatcaacgg ggcgtcgttc cgcaagcccg
     2641 cgggcgcgcc ggggacgggc gcgtccggga cggtggagcc gcatgccgcc gccgcggacc
     2701 gggcctcggc caccaccggc gtgtggcggg acgtgttctc accgcggcgc ctggggctgt
     2761 tcaccgccgc actgctgctg atggaactca cccacaccct cggcttcagc atgttcgtcc
     2821 cgctgctgac cggcggtgcc gccgaccgtt cctggatcgc cggcacggcg aacgcctgct
     2881 tcgccctcgc ggcgatgatc agcggggtgc tggtctccgg cggcgcgctg ggccagtgga
     2941 ccagggcccg ggcgccgcag gtcgtcctcg tcggcttctg cgtccagatc gtgttcggcc
     3001 tgagcgtcgc gcacccggtg tgggcgatcg ggctctacgc cgtggtgggc ctgctcagcg
     3061 ggggcgacgc ggcgttgcag agcgaagtcc aggaccgctg gcgcccggcc ggctcgtccc
     3121 aggcgttcgc cgtcttcggc gcggtgcagg ggcccgcgca actggtcggg tccctcgccg
     3181 tcgccgcact gttgacctgc ctgtccgtgg ggacggtcta cctcggcacc gtggtggtgc
     3241 tgggcctggg ctcggggctg gtgctgatgc tggcccgatc ccgggccgag gcaccgccgc
     3301 cccgcgtcga ggcccccgtt tgacgccccg gtgcctccgg ttccaccccc ggaccggcct
     3361 gccgaaaccc gatggaattc acgaaaggaa ccacgacgtg gccaaccttg ccttgtacgg
     3421 tctcggcgaa atgggcgcgg acatcgcgcg gtgcctggtt tcccgcggtg tcgcactgca
     3481 cgcgtacgac ccggtgtccg acgtgacgtt ggcggcgggg aacttccacc gctgctcgac
     3541 ggcggcggag gcggcccgtg cggccgcggt ccacctcgtc gtcgtcaagc ggccggacga
     3601 cgtgcgcgcc ctgctcttcg gcgccgacgg gctgtgcgcc gcggcgcccg ccggctccca
     3661 cgtggtgctg cacaccaccc tcaccccgca gaccgtccgc gaactggccg aggaggtgcg
     3721 gcggcagggg cacgtcctgc tggacgccgc cctcagccgg cgcaacggtc tgatccgcga
     3781 gggttcgctg tccctgttcg tgggtgggac ggccgaggag gtcgccgccg tggggcccgt
     3841 cctggaccgc tacgccgaca acgtggtgca cgccgggccc accggcgccg ggatgaccgt
     3901 caagctctgc aacaactggc tcctctacag caaccggcac gccgcgctcc aggcgctcgg
     3961 caccggacgg gcgctcggcg tcgaccccga cgtcctgcgc ggcgcgctgg cctcgtcgac
     4021 cggttccagt tgggccctcg cgcactactc ggacctcgac gaggcgatcg tcacgggcca
     4081 gggcgccccg gccgtggtgc gcgaccggac cacgtccgaa ctgcacatgg cccgggacat
     4141 ggccgccgcc aacggccagg tgcccaccag ccttcaggag accttcgcgc tgctcgacgc
     4201 gatgtgagcc cccgtcccgc cggcgccggg aagccggccc cgcccgtccg gaagggcgcc
     4261 catgcacact gacatcgttt cccccgacga gctcgacaag gccgtcgccg gcctgcccgt
     4321 gcaggtgtgg aacgcgccga cggcggccga actctacgga cagaccctca acctcgtctg
     4381 ccggacccgc ggcggccgca cggcgggcgc ctgggtggtc cccctggacg acgacggaac
     4441 ggccgcccgc cgtcccttcc gactcctgcc ctacgcctca ccgtgggtgg acccggaact
     4501 gcaccccgtc gaccgccacc gggcggtgct gtcgatgacc caggcactca tggaccgggt
     4561 ggagtcggcg gagataccga tggacccgcg cttcggagag gcggccgccc tggccgaggc
     4621 gggggccgaa ctcctctgcc ggcacacccg cgtcctggaa ctgcacgccg accgcgaccc
     4681 ccgcacgggg tacgtggcca ccgcccggaa ccacatccgg gccgcggccc gggagcacac
     4741 cgtgcggacc gccccgctcg acgcgttcga cttctcccgc gcggtcgtcg gccaaccgcc
     4801 ggacgccgtc gccgcgcggc gcaggtccgg gctgcgcgtc ggcggtgtcg aaccggcgct
     4861 gtgcctcgcc gcgacggacc ccgacgggac ctgccggggc caggtgttcg tcctgctctg
     4921 cgacggcgcc gcggtcctca tgcactcgtg gttcgaccgg gcgggcgccc gcggggtgcc
     4981 gagcctgctg gtggacgagg cgatcgcgtg ggcgggccgg cagcccggca ccgacgtgtt
     5041 cgacttcgag ggcagcgtgc tgcccggcgt cgaccgcttc atgaccgggt tcggtgcccg
     5101 tgcctgcgcc tacccgcaac tgcggtggcg ccgctcgacc gaaccgggcg cgggagcggg
     5161 ggagttcgga tgaccgccac cgaccggccg accgaacccc accccggcac cgacccgccc
     5221 agggcggccc ccgcggcgcg gcaccgcccc gcgccggccc gggccgcccc gccccccggg
     5281 ccggtccacg acctcaggat cgtcgacctc gacgccctca ccccggccca ggaaggagcc
     5341 tggacgacgg cgtaccggcg gcacggcaca cggttgcagc agtccccggg gtacgcccgc
     5401 gcggtgcgcg ccgcaggcca tcgggtcgtc gtcgccctcg cgcccgacgg catcgccgcc
     5461 ttcaccgacg agggcgcggt gctcacggcg gtctgcgccg acgagcccgt gctgaccgag
     5521 cacggccagg cggagcgcct cgcccgtctg gtgacggccg tccaccgggc caccggcgcg
     5581 tccgtctacc tgcccctggt ggccgcggcg cacgccgagt cctgcgcccg cgccgggtgc
     5641 acggtctggc gccgcccgcc caactccctg atcgactggt cccgagacgg cgccgacctg
     5701 tgggaacgcg ccctggcacg cggctcctcc caactgcgcc ggaaacgacg cctggtggag
     5761 cgcgacggcc tgacgctacg gcccggaacg tccggtgcgg gcgccttcgc acacgtcctc
     5821 gcggtcgacg accgctcgtg gaaggcccgt cagggacaga gcatgcggct gcgcggcggc
     5881 caggacgcgc tctacggacg cctggtcggc accggcgagg tcacggccgc cctgctcctc
     5941 gacggcgagc ggccggtcgc cttccgcctg gacgcccggg tcggggaccg gctggcgagc
     6001 ctgaagtggt cctacgacga ggactaccgg cgctactcgc ccgggctgta cctgctgacg
     6061 gagggactgc ggcaggagtg ggcgggccgc ggggtgcgca cggtggacct gcacggcagc
     6121 cccgacgcgc tgaaggacct gctccacagc gaacgcgtgc cgcgggccga cgtgtggtgc
     6181 ggcgccgcgg accgggccgc cctccgggca cgtgagcgcg cggacctgga cgcccgggtg
     6241 gcccgtgcac acgaggcggg gaaggggctg cgccatgcct tcgactgacc ccgtggtgga
     6301 cgccgcggtc cgggacctgc tggaccgttg ggggcagccc gccgcggcgt tctgcgcctc
     6361 cggcggcgcg gcgctggaag cggccctgga agtgctggag gtgggcgcgg gcgccgaggt
     6421 cgtggtgccc gacgtcggct gccactccgt cgccgcggcc gtcgtccggg tcggcgcggt
     6481 gccggtgttc gtcggcgtcg gcgagggctt gaccctgcac ccgccggacg tggcggcggc
     6541 gtgctccgca cggacccgcg cggtcatcgc ggtgcaccag tacgggctgc cgtgcgacgt
     6601 gccaggcatc gtcgcggccg tcccgcgcgg cgtggcggtc atcgaggacg tggcccagac
     6661 ctggggctcg acgacccggg gcgtgccggc cggctccacc ggcacgctca ccgtcacctc
     6721 gttcgggccg tccaaaccgg tcgcgttggg ggccggcggt gcgctcctcg gcccggccga
     6781 cctggtgtcc ggtgccgtcg cgcggggcga cacgtcggac cggcaccggc cgcgtccccc
     6841 gtcacccgcg cgcttcccgg cgcccctgta ccccctgctc ccggccgccg tcgccgaggc
     6901 ggaccgccaa ctcgccagtc gcagggcggc ggttgagcgc ttcaccggcg gtgacttggc
     6961 caggcacttc cgcctcccgg gtctgctgcc cggctccagc gccggttgga cccgcgtgcc
     7021 gctctacccg gcaaggtccg caacgcccca ccacctcgcg cagctgacgg acgccctggg
     7081 ggccgcccaa cggatgcatc cgcgcccgcc gtccgccctg ccgatgttcc ggggccgcga
     7141 cacccgcgtg gtgaccggca cccgtcggcc cgtggaaccc cttctcgtca agattggacg
     7201 accctcatga cggtgatcaa tccgcaccag ttcttcgacc tgtcgcggga ggaccagcag
     7261 tccctcaccc acttccgggc caccctcgcc gacggccagc tcttccgcta cgtcgagggg
     7321 gaccgcgagt ccgcgaacac gctcatcgaa cgccacttcg ccgggtactt ccgcaaggag
     7381 gccgccacgg cggtggccaa cggcacggtc ggactgcgcc tggcgctgcg ggccctgggc
     7441 atcggccccg gcgaccgcgt cctggtcagc gcctactcct tcatcgcctg cgcgatggcg
     7501 gtctccgcgg tgggcgcggt gcccgtcccc atggacatgg acaccgccct cacccccgac
     7561 acggccgcgc tggaaacgcc ggacgaaccg gtcgccgcgg tgatggtcgt ccacgtgcag
     7621 gggcacgccg tgccggcggg gcggctgcgg gagctctgcg accggttggg cgtcccgctg
     7681 atcgaggacg tctgccaggc actcggggcg gcgtccgcgg acggtcgggc cggtgagctc
     7741 gccgacgtcg ccgtcaccag cttccaacag tccaagcaga tctcctccgg cgagggcgga
     7801 ctggtcgccg gtggcgccga ggtcgtggag cgggtgtacc ggatggcgga cctgggcgcc
     7861 gtccggcacg acggcggcct gcccgactgg gacgacgaac gggccctggt cggggacaac
     7921 ctgcggatga ccgaactcca ggcggccctg gtgatggacc aggccctgac gctccatcag
     7981 acgctggccc ggcagcgggg cctgcgcagc agcctgcggg agcaactcgg cgccgacaca
     8041 ccggtcctgg acagttcgcg cccggaaggg gacgcggcgt cacacaccct gttcgtggcc
     8101 cgcagcaccg ccgacgccgc ggagttctgc accgggctcg cggcccgcgg cgtcctcgcc
     8161 cgcgtggtct ggaagaagac ctaccctgag tacggattgt tccggcgcgt gctgccgagc
     8221 gcaccacacc cgtggccgaa gaaggcagag gcgctggcgc ccaggatcct cagcgttccg
     8281 acctcgaagt acctgacgga tgcagccgtt tcccaggtgg ccgaggccgt cgtggcgcac
     8341 cgacaccatc tcgtccagga aaggtaacca ccccgatgaa ccgcatcgcg ctgctgctgc
     8401 gcggtctgcc cggctccggc aagaccacca ccgccgccct gctgcgggac tctctggtcc
     8461 ccgccgtccg gatctccaac gactccgtcc ggtacatggc ccggccccgg gacttcagcg
     8521 acttcaccct cgtggcctcc gagctcggct gcctcgacct ggccctgtcc tacctcgaca
     8581 gcggcttcac ccccgtgatc gacggcgtct tcgaggacgt ggacttcctg gccgcccagg
     8641 aactgcgctt ccaacggaag ggcatgcgcc tggtgacgat caccctggac ggcacgctga
     8701 ccgacctgct ggaccgcaac aacgcccgtg acccgctggc gcgcatggac gaggaccggg
     8761 tccgcgagct gcaccagcag ttccgccccg ccggcctgct gctcggcatc cacgacaagc
     8821 aacccgagga ggtcgcggac gacgtcctgg acctcctcga actcaccgcg caggaagccg
     8881 ggaccgagcc cgaggccacc gagaacgtgg acgtgctgtt ccttcggcac ggcgccccgg
     8941 actacccgag cgacacctac cccgacccgt acgcgatggg gctgtccgcc cgcggccgcg
     9001 acgaggcgcg gtccgcccga ggagccgtcg aacggttcgc acccgacgcg gtgtacgcct
     9061 ccgacttcct gcgtgcccgg gaaacggcca cgctggtcac cgccgcactc gacgtcgagg
     9121 tgcagcagga agccgccctg cgcgaacgcg tcttccacgg cttcgccggc gtcgacctgg
     9181 acgacgtacg acgacgcctc ggccccgaag ccgaccgggt cctgaccggc aacagcgacc
     9241 tgtgcacggt cgacggcgag gagagctacg aacaggcccg cgaccgggtc ctggagttct
     9301 tcgccaccct ggccgcccgc caccccggcc ggcgcgtgct ggtggtgggg cacggcggac
     9361 cgcaccactg gctgctggag cgggccttgg gcgcggacct gcgcggagtg cgcgcgctgc
     9421 gctgggaaac cggccacttc tcgcgcttcc ggatcgcccc ggacggagtc tcggtggact
     9481 tcgtcaaccg ctcgcccgag gacgtcgccc gcagcccgca gcccgccaag gaggccccat
     9541 gaccctgcgc tcaccgctcg tcggcggccg ggcccgggtg gcggtggtgg ccacgccctt
     9601 cggcttcggg ccctcctcga aggcgtacag catcggccag gtgctggccc gggaccacca
     9661 cctggacgtg gcgtactacg gcaccgactc cgcgctcgac ttcttcgccg cgcaaccgga
     9721 cgcccccgcc cgcccgttgg acgacccacc gccgggacag gacccaccgg ccctgcgatc
     9781 cgcggacgcc gtggtcaacg tgctggcccc cgagctgatc ggcacggacc gcctggccgc
     9841 ccgcacgtac tacgtcgaca gcctcggctt catgtggacg gcggccgacg tgccgccgga
     9901 cagcccgctg caccgggtcc gcgcctacct cgcgcaggac ctcttcggca gcgtcgccca
     9961 cctggcccgg ctcggcctgc gcgacgtgat cccggtctcc gggatcgtcg cccggccccc
    10021 cgccgcgccg ccgacggtcc ccgccccggc gggcccgccc ggagggaccg ccgcgcgggg
    10081 cccgggccgc ccccgggtgc tggtgcagct cggcggcctc ggcaacccgg ccggacacac
    10141 ctccggccgg gtgtacctgg cactggtgga gcggctgctg gccgccgtgc gggacgactc
    10201 ggccgtcgag atgaccgccg ccatgaacca cgccaacggc gcgttcaccc tgcgggccgg
    10261 tgtgccggtg cgccagctgt ccgccgcgga cttccacacg gcgctggggc ggtgcgacgt
    10321 ggtgctcagt tcccccggga tgaccaccct cgtcgaggtg tcccgagccg gccggcccta
    10381 catcccgctg cccccacaga actggagcca agtcctcatc tgccgacacc tgtccgcccg
    10441 ctcggcccac gacctgtggc cgttcctcac cgcgccctac gacggcatcg ccgagggggc
    10501 acccgaggcg gcgaaggccg tcgccgtcca ggaggtcaac cgacggctcg gccgcgacga
    10561 cggatacgcg gcgcgttacg cacgactggc ccggcacgcg gtgggaaacc ccgagacgcc
    10621 ggacctggga gcccccttcg acggggcgca cgaggtggcc gcggtcgtgg ccgcggacct
    10681 ggccgctcgc cgcagcgcgg tcgagccgac gacggaggca acagcgtcat gaccgaaccg
    10741 accaccgcac gcacccgatc cgccctcctc accaccctgc actcgctcgc cggcgaggtc
    10801 gacggggcac gggagtggag ccggacctcc cggaccatgg caccggcgcg cgtcgccacg
    10861 gtgttcggct cggcccgcgc cgaacgggac gagccggcct accagatggc cagggaactg
    10921 ggcgccgccc tcgccgcccg gcgctggacg accgtgaccg gcggcggccc cgggatcatg
    10981 caggccgtcc gggacggcag cggcaccacg ctgtcccggg cggtgcgcat cgagatcccc
    11041 ggagaagtgc ccgacacggt gctcgacgag gaccgttcgc tcaccgtcgg caccttcgcg
    11101 ctgcgcaagc tgctcctcac ccacgacatc gacgcgctgt tcgtcttccc cggcggggtg
    11161 ggcacgttcg acgagctctt cgaggtcctg gtccaccacg acaccgaccg gctcgaccgc
    11221 ttccccgtgg tgctcgtcca acccgaaggc accggcctgt ggcaggcgtt cgtgcagttc
    11281 gtccaggcgc acctggtgga cgccgggctc gccagtccca cggtggtcaa ggaactcgtc
    11341 gtcgccgagt cggtggaggc ggcgctggcg gccgtggggg cgcacccacc ggccaccgtc
    11401 ccgcagccgg gaaccgccac cgcgccggac gccaccgcag acctcggcac ggaacggcgg
    11461 acggcatgac cgagcacgcc cggccgccgg ccaccgagca ccgccccgtc gacgtcagcg
    11521 tcatcatccc cgcctacaac gcgtgcgcca cgctggaggc gtgcctgctg tcgctgacgc
    11581 accaacgacc gcaaggaaaa gggtcgttcg aggtgctcgt catcgacgac ggttccacgg
    11641 acggcaccgg cccgatggtc gactccttcg cctcccgcct ggacctgcgc tacgtccacg
    11701 agccccgcac cccggcatcg ggacgcgccc gggcgcgcaa catcggactg gccctggcca
    11761 ccggcagcct ggtcgtgacg ctcgacgccg accaggtcgt gggccccgac ttcctggcgg
    11821 agcacctccg cgcgcacggc accgccgacg acctgctggt cgtcggccgg cgccaccaac
    11881 tgggggaggg cacgttcgac ctggcgcgcc tggcccgcgg gttcagcctc ggggcgctgc
    11941 cggaggtggt gcgcggcgac gaacgcgaac cggtcctcgc ggcgctgggc ggcgagctga
    12001 gcgacctgcg caccgcctgg cactacctgt ggacctgcaa cgcctcggtg cggcgcgacc
    12061 gactggccgc cgtcgggggc ttcgacgagg agttccacgg ctggggcctg gaggacgccg
    12121 agttggggta ccggctcgtt caggacggcg tccggatgcg ctacagcacc cgcgccgccg
    12181 tctaccacga acaccgctcc ccggtctccg cgtcgatgta ccgcgaatgg cgcgcgaacc
    12241 tcgcccactt cgcccgcaag caccccgccc ccgtggtccg gctccaggag atgttcgcgc
    12301 ccgccatcga tccggccgca ccggcggcgg aggcatgggt ggacaccgcc gtgcggttcg
    12361 agcaccgcgc ccgggcactg gccggcgtcc cgcagccggc ccaccacggg tgagccaccc
    12421 ccaccccttc ccaccgacgt cctgagaggc tgcgtcaccc accatgcaca ccccaccgga
    12481 accgagggcc gggagcggcg cgccgcgccc cgtgcgacgg ctcgtgtacc tgcccaccaa
    12541 ccgccccttc gaggcggcct tccgctccgt cgccgccgag gtcgcggcgc tacccgaggc
    12601 ggcgcgccag caggtgacga tgctggtggt ggacgactgc ccgccgccgg tctcccgggc
    12661 caaccgccag gtcgccgagg cggccgccgc gaccgccggc gtcccggtgc acgtgctggg
    12721 cgcggacgga tggacccgct tcgtccacga cctcctcgcg accgccgcgc tcccgccggc
    12781 cgaacgcacc gtggcggaag gcgccctgtg caagccgacc ggttcctacg gcgccggccc
    12841 caacaaggcc gcactggtcg ccgcgtacct gggcgcgcgg accctgcacc ggcgcgacag
    12901 cgaccaggtg acccacgtcg accccgcatc cggcgcctct ccgctgcgga tcgaggcgga
    12961 actgctcgac gggggcgacg cggccgggag caagggcgcg tactgcgtcg gctcgtccct
    13021 caccggccgc cccacccgcg accgccgcga cctgctggac cgctccgagg agttcgtcga
    13081 ccgcatcgat gccctgagcc ggctctcccc ggccgagacc cgggtggccc ggcccgcggc
    13141 cccggcccgg cccgaagagg tcgtcgcgca cggcggggtg ccggcccacc gcgaccacac
    13201 cggcgtcgtg gagatgggca tcgccgccct gcgccgcgtc cacgagtgga tcccggagat
    13261 gcccgcggtc ggggtgctgg gcagcgacta cttccaaaag ggactgctct accagctcga
    13321 actccccgtc tggcaccacg acctgaccgc cgaccaccac tacgagccgt ggcgggcgga
    13381 acagagcagc gccgcacacc tcggctggta cgcccgcgcc gaactgcgct acgccgtgct
    13441 gcgcaagcac tggaacgcct tcaacgaggc cctgatgacc cagcgcgacc tgctgctgcc
    13501 cgacgggcag cacttcgact cggcggcgta cgcggacttc ctcctcgaca ccgtggagcg
    13561 cggcgcggag cgcacggcgg ccatcccgtc cgcgttcgtc gagatctacc gcgaggcggc
    13621 cgccgccgcg tcgggcgacg tccggagccg cctcgacgtc cgcgtcgcgg ccctggagga
    13681 ggcggcggac acgaccgggc agtacgtggc cgacgccgtg cgggagttcg cggcgctgac
    13741 ccgcagttgg cccgcactgg tggcggcggc gggccggctc ggcgtcgacg gcgacctcgg
    13801 acggtacgcc tgacccgcgg ggtccgcccg tccgcccacc cccgaaaacg ttgcggaaga
    13861 gcgctgcggc ccgccaagga agccgcactc acggactgac aaggagatca ccatgtgcgg
    13921 catcggcggc atcctgctga aacgacgccc ttccctcgac caccgggcca tggccgtgcc
    13981 gctcggtgca tccctggccc accggggccg ggacggaacg ggagccttca gcgacgactg
    14041 gatctccctg cactccgccc ggcacgccgt catcgccgtc gacgacgccc gccagccgct
    14101 cttcgactgc gagcgcgcgc tggtgatggt gggcaacggc gaggtgctca actaccggga
    14161 actcagccac cggctgcccg ccgaccggcg ccgccggatg ccccccggcg acctccaggt
    14221 ggccctggaa ctctgcgccg agcgcggcac cgcggccttc gaggacctgc gcgggccgtt
    14281 cgcgctggcc gtgtgggact ccaccgccca cgaactgacc ctggtccgcg accggctcgg
    14341 cgagcgcccc ctgtactact acgactcgcc cgacctgttc gccttcgcct cggagctgcg
    14401 ctgcctcacc gcgtgcctgc gcggcgaaac cctccgcctc gacccggcca acgccctggc
    14461 cttcctgggc ctgggccgcc tcccggggga ccggacgctg taccaggacg tccggtccgt
    14521 gccggcgggc ggcgtgctcc ggatcgcccc cggcgccgcc ggcccgcgcg cggcggcccc
    14581 gctcaccccg gtgtccggcc tgcgggccgc ccccgccgac gagaccgaga tcggccaact
    14641 catcgaccag gcgcaccgcc gcgccctggt cgcggaccgc ccggtcgccg tggggttctc
    14701 cgggggcatc gactcctccg cggtgctcaa ggcggcactg gagcacgcgg agcccgcggc
    14761 ggccgtcacg gtgttctcgg cccgctgccc cgacgaggac gagaacctgc gtcgggcccg
    14821 cgccctggcg cggaagttcg gcgtcgacct gcacgaggtg ccgttccgca tcccgtcgct
    14881 cgacgccacc gcggacctgc tgaacgacac cctcgacgca cccgccgcgg agccgctggt
    14941 gctgcacaac gacgccctgc accgcgccgc gcgggagcac tccgccgtgc tcctgggcgg
    15001 ccacggcgcg gacgaggtgt tcggcggcta tgtccgctac gccgcgctgc gcgcggacgc
    15061 ggtggacgcc accaccgagg agtggatggc catgtcgctg tgggaacgct ggaaccgcac
    15121 cgccggctgg cacaagttcg tgacggactt cggcagcgac gccgtcgcgc cccgcaccgc
    15181 ggcgctcggc gacgtcctgg accgcccgtt cccctactcg tcggccgagc accgcgaccc
    15241 ggtgctgttc ggacaggccc tcgacctgtt ccggctgatg acctacgaca acttccgcgc
    15301 gacggacgag aacgggatcg cccggggcgt ggaggtccgc tcgccgttct tcgacatcga
    15361 tctggtggcg ggcgtcttca gcctgccggc ggagcggcgc atccgcccgg acgcgcccaa
    15421 gcacctgctc cgcggcgtct tccgcggcac gccgctggcc ggggagttca ccgagcgcaa
    15481 ggtcggcttc gacgaccact tctcgtactc ggactggatg accgacaact ggcccgactt
    15541 ctccgccgcc atcgtcgacg gcccgctgac cgacctcgga atcctgcgcg acggggccct
    15601 cgccgacctg gagaagttcg actggcgcct gctgtggcga ctgttcagcc tctccacgtg
    15661 gctggagcgg gagggccgcc cgccggtcgc cgggaactga gggagcaccg ggacccccga
    15721 acggccgccc gccgtaggcg gtcagccgtt cgggaggatc accgcacgac cgtcgatcag
    15781 accggcgtgc agccgctcgt aggccagtgg cgcgtcgtcc agggagaacg tctcggtgtg
    15841 gacggagacc gcaccggagc gggccagcgc caacacctcc agcaactcgc cccggcttcc
    15901 ccagtacggt gcgctgaccg acacctcgaa gggcagctgg ccgaagccga ccggcagggc
    15961 ggcgccgccg atgccgacca ggctgacgtc ggcctcgatg gcggcgaccg ccgcggccgt
    16021 ggccacggtg ggcgccgccc cgacgaagtc gaacacggcc tgcgcgccga tcccgccggt
    16081 gagttcgcgc accgcgtccg cggccccgga gtcggaccgg accgcctcgt gggcgcccat
    16141 ctcgcgggcc agccgcagct tgtcgtcgct cacgtcgagg gcgacgacgc gggccggggt
    16201 cagggcgcgc agcagttgga tcgcgacgtg cccgaggcca ccggcgccga tgaccaccgc
    16261 ggtggacccg ggcgtcagct tgggcagcga ccgcttgatc gcgtggtacg gggtcagccc
    16321 cgcgtccgtg agcggtacgg cggcgaccgg atcgagtccg ccgagcggca ccaggtgccg
    16381 agggtcgtcc accaccaggt actcggcgat ggctccgggc gcgcccagac ccggcggacg
    16441 gatgccgagt tcgtcggcgc gcaggcagta gttctccttg ccctccgcgc acttggcgca
    16501 ggttccgcac ccccacgggc cgtacacggc gacggcgtcg ccctcctgca ccgcggtgac
    16561 gcccgggccg agcgcggcga ccgtgccgac gccctcgtgg cccagggtga gcgggagcgg
    16621 gtaggggaag ccctcggcgg ggcggttcat gacggcgaag tcggagtggc acacgccggc
    16681 ggcggtgacc ttgagcagca cctggccggg gccgggcgtc ggatcgggaa cgtgcacgac
    16741 ctcgggcgga gcgccgatgg tgcggtactg gagggccttc atgacggggt tctttcctgc
    16801 gtggtggtgc gggggagggg aggggagggg gcggaacggg cgcccgccca ggggcgcccg
    16861 caccgctacg ggaagtcggt cggccggccg ccggcggcgg cctcgtgggc cagggcgtcg
    16921 taggcgccct ccaccagggc ggcgaggtcg ttcgcgggcg gctcgccggc gtccgcggcg
    16981 tgggcccaga cgcgcagggc ggcgctgagg acgccggcgg acgcctcgac gaccacggcc
    17041 gggcgcatgt cgtgctcgtc ggtgccgagg cgggccgcga ggatccggat cgattcccgg
    17101 tgcgcgtcga cccggatgcg ttcgtacgcg gcgaagagcg ccggctcgcg gtccaccagg
    17161 gcgagcaggc gccgcgtctt gggctggagg tgccagccgg ggctctgctc gtcggcgagc
    17221 caggcaccga cggccctgcg gtaggccagt agcggcggct cggcggcggg gcggatgcgc
    17281 agcagggcgt tgatgcggtc gccgtcgccc cggacgaagt cgagggcggc gtcctccttg
    17341 ccggcgaagt gccggctgaa ggtgcgccgc gtgacgtcgg cgcgttccgc gatcgcctcg
    17401 accgtcgtgt cggcgaggcc gcgctggagg atcaggtcga gtgccgcggt ggccagtgcc
    17461 ctgcgggtcc gtcgttccct gcgccgccgg cggtcctcgg cgggggcgcc ggcggcgtcc
    17521 ggggaaggtt ccggcaccgt catgtttgcc acggtacacc cgttgtgtcc catcgagaca
    17581 tgtgtcccat ggggacactc cgggaggggg cggcgcggca cccggcgccg cgct
//
