BGC0001611: guangnanmycin biosynthetic gene cluster from Streptomyces sp. CB01883
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Location: 1 - 72,893 nt. (total: 72,893 nt).
This entry is originally from NCBI GenBank MF925481.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001611
Short description guangnanmycin biosynthetic gene cluster from Streptomyces sp. CB01883
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
MF925481.1
via
Compounds
  • guangnanmycin
Species Streptomyces sp. CB01883 [taxonomy]
References
Chemical products information
guangnanmycin Evidence: NMR [1], Mass spectrometry [1], [2]
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATY69549.1
 976 - 2301 (+) putative lanthionine synthetase
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    • ATY69550.1
    • gnmA
    		 2571 - 3008 (+) truncated hemoglobin
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      • ATY69551.1
      • gnmB
      		 3051 - 10070 (+) hybrid nonribosomal peptide synthetase/type I polyketide synthase
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        • ATY69552.1
        • gnmC
        		 10168 - 10926 (+) type II thioesterase
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          • ATY69553.1
          • gnmD
          		 10949 - 11716 (-) 4'-phosphopantetheinyl transferase
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            • ATY69554.1
            • gnmE
            		 11909 - 13141 (+) HMG-CoA synthase
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              • ATY69555.1
              • gnmF
              		 13149 - 13955 (+) enoyl-CoA hydratase
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                • ATY69556.1
                • gnmG
                		 14050 - 16539 (+) acyltransferase/oxidoreductase
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                  • ATY69557.1
                  • gnmH
                  		 16686 - 23213 (+) type I polyketide synthase
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                    • ATY69558.1
                    • gnmI
                    		 23260 - 24816 (+) antibiotic efflux protein
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                      • ATY69559.1
                      • gnmJ
                      		 24960 - 25859 (+) hypothetical protein
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                        • ATY69560.1
                        • gnmK
                        		 25856 - 28267 (+) acyltransferase/oxidoreductase
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                          • ATY69561.1
                          • gnmL
                          		 28312 - 29244 (+) hypothetical protein
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                            • ATY69562.1
                            • gnmM
                            		 29371 - 29736 (-) glyoxalase/bleomycin resistance protein
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                              • ATY69563.1
                              • gnmN
                              		 29851 - 30258 (-) hypothetical protein
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                                • ATY69564.1
                                • gnmO
                                		 30480 - 31196 (+) N-acetylglucosaminyl deacetylase
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                                  • ATY69565.1
                                  • gnmP
                                  		 31255 - 32001 (-) methyltransferase
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                                    • ATY69566.1
                                    • gnmQ
                                    		 31998 - 34106 (-) putative alpha/beta hydrolase
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                                      • ATY69567.1
                                      • gnmR
                                      		 34450 - 34704 (+) peptidyl carrier protein
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                                        • ATY69568.1
                                        • gnmS
                                        		 34701 - 36329 (+) adenylation protein
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                                          • ATY69569.1
                                          • gnmT
                                          		 36326 - 58594 (+) type I polyketide synthase
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                                            • ATY69570.1
                                            • gnmU
                                            		 58591 - 59838 (+) HMG-CoA synthase
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                                              • ATY69571.1
                                              • gnmV
                                              		 59858 - 60133 (+) acyl carrier protein
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                                                • ATY69572.1
                                                • gnmW
                                                		 60157 - 61428 (+) beta-ketoacyl-ACP synthase
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                                                  • ATY69573.1
                                                  • gnmX
                                                  		 61544 - 62797 (+) cytochrome P450 oxygenase
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                                                    • ATY69574.1
                                                    • gnmY
                                                    		 62854 - 64155 (+) aminotransferase
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                                                      • ATY69575.1
                                                      • gnmZ
                                                      		 64119 - 64808 (-) Crp/Fnr family transcriptional regulator
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                                                        • ATY69576.1
                                                        		 65382 - 67667 (+) AfsR-like regulatory protein
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                                                          Biosynthesis information
                                                          Annotation changelog

                                                          Entry version: next

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2024-05-14
                                                          MIBiG v4 annotathon
                                                          • (ID: Z4WHVO6K4QR4NSPFS3BTTXEO)
                                                          • (ID: YO3TP6VWB5CBNPZKNYNQSKUW)
                                                          • (ID: P75FRHHCFPTCPYSP65VDVPHW)
                                                          • (ID: I3D2K5SU7JJDS2LEEQM3W3SO)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 3

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Added NRP substrate specificities
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2019-10-16
                                                          Migrated from v1.4
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2018-08-06
                                                          Submitted
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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