BGC0001612: ambiguine H isonitrile biosynthetic gene cluster from Fischerella ambigua UTEX 1903
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Location: 1 - 41,276 nt. (total: 41,276 nt).
This entry is originally from NCBI GenBank KX451322.1.

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core biosynthetic genes
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001612
Short description ambiguine H isonitrile biosynthetic gene cluster from Fischerella ambigua UTEX 1903
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Alkaloid
Loci NCBI GenBank: KX451322.1
Compounds
  • ambiguine H isonitrile
Species Fischerella ambigua UTEX 1903 [taxonomy]
References
Chemical products information
ambiguine H isonitrile
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C26H32N2
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • APB62238.1
  • famA1
1 - 456 (+) hypothetical protein
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  • APB62239.1
  • famA2
464 - 1657 (+) DevB family ABC transporter membrane fusion protein
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  • APB62240.1
  • famA3
1681 - 2847 (+) ABC transporter
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  • APB62241.1
  • famB1
3254 - 4204 (-) 2OG-Fe(II) oxygenase
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  • APB62242.1
  • famB2
4329 - 5186 (-) Rieske oxygenase
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  • APB62243.1
  • famC1
5624 - 6307 (-) Stig cyclase
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  • APB62244.1
  • famC2
6704 - 7396 (-) Stig cyclase
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  • APB62245.1
  • famC3
7726 - 8409 (-) Stig cyclase
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  • APB62246.1
  • famC4
8736 - 9455 (-) Stig cyclase
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  • APB62247.1
  • famB3
9510 - 10601 (-) Rieske oxygenase
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  • APB62248.1
  • famB4
10909 - 11991 (-) Rieske oxygenase
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  • APB62249.1
  • famB5
12079 - 13158 (-) Rieske oxygenase
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  • APB62250.1
  • famD1
13458 - 14489 (-) aromatic prenyltransferase
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  • APB62251.1
  • famE1
14654 - 15892 (-) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
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  • APB62252.1
  • famE2
15929 - 16969 (-) polyprenyl synthetase
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  • APB62253.1
  • famF1
19516 - 20232 (+) LuxR family transcriptional regulator
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  • APB62254.1
  • famF2
20464 - 21198 (-) LuxR family transcriptional regulator
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  • APB62255.1
  • famG1
22691 - 23269 (+) dephospho-CoA kinase-like protein
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  • APB62256.1
  • famE3
23334 - 24554 (+) 1-deoxy-D-xylulose 5-phosphate reductoisomerase
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  • APB62257.1
  • famH1
24860 - 25819 (+) Isonitrile synthase
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  • APB62258.1
  • famH2
26011 - 27003 (+) Isonitrile synthase
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  • APB62259.1
  • famH3
27003 - 27824 (+) Isonitrile synthase
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  • APB62260.1
  • famD2
28301 - 29230 (+) Aromatic prenyltransferase
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  • APB62261.1
  • famE4
29487 - 31430 (+) 1-deoxy-D-xylulose-5-phosphate synthase
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  • APB62262.1
  • famE5
31503 - 32729 (+) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
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  • APB62263.1
  • famI1
32944 - 33849 (+) 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase
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  • APB62264.1
  • famI2
33903 - 36107 (+) anthranilate synthase subunit I
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  • APB62265.1
  • famI3
36347 - 37198 (+) indole-3-glycerol-phosphate synthase
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  • APB62266.1
  • famI4
37250 - 38062 (+) tryptophan synthase subunit alpha
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  • APB62267.1
  • famI5
38224 - 39474 (+) tryptophan synthase subunit beta
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  • APB62268.1
  • famI6
39510 - 40607 (+) anthranilate phosphoribosyltransferase
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  • APB62269.1
  • famG2
40632 - 41276 (+) phosphoglycerate mutase
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
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