BGC0001615 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001615 (Heteroscytonema crispum UCFS10)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	mycosporine-like,NRPS	1	10,987	hexose-palythine-serine/hexose-shinorine	NRPS:Type I	100%

BGC0001615 - Region 1 - NRPS,mycosporine-like

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Location: 1 - 10,987 nt. (total: 10,987 nt) Show pHMM detection rules used

Region on contig edge.

mycosporine-like: (DHQ_synthase and Methyltransf_3 and ATP-grasp_3)
NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 10,988
Label		BGC0001615

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615	2.00	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000427	0.82	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001833	0.52	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001678	0.51	Other	mycosporine-like amino acids (MAAs)	Symbiodinium sp. clade A Y106
BGC0001132	0.49	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128	0.49	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825	0.49	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844	0.48	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758	0.47	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0002286	0.46	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615	1.00	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000427	0.73	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001833	0.60	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001678	0.59	Other	mycosporine-like amino acids (MAAs)	Symbiodinium sp. clade A Y106
BGC0001132	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128	0.58	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825	0.58	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844	0.58	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758	0.57	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0002286	0.56	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 10987:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

mysE

Search NORINE for peptide: strict or relaxed

AMP-binding (472..872): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: ser (Ser)
Single AA prediction:: ser (Ser)

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLIDK
Nearest Stachelhaus code(s):: Ser DVWHISLIDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)