Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001619.1:
Cluster 1Polyketide1334748

BGC0001619, ibomycin biosynthetic gene cluster from Streptomyces sp. WAC2288. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: ibomycin

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Modular Type I

Gene cluster description

ibomycin (BGC0001619). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank KJ159185. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Robbins N et al. (2016) Discovery of Ibomycin, a Complex Macrolactone that Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function. Cell Chem Biol 23(11):1383-1394. doi: