BGC0001621: imizoquin A biosynthetic gene cluster from Aspergillus flavus NRRL3357
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 25,905 - 53,073 nt. (total: 27,169 nt).
This entry is originally from NCBI GenBank NW_002477244.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001621
Short description imizoquin A biosynthetic gene cluster from Aspergillus flavus NRRL3357
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: NW_002477244.1
Compounds
  • imizoquin A
  • imizoquin B
  • imizoquin C
  • imizoquin D
  • TMC-2A
  • TMC-2B
Species Aspergillus flavus NRRL3357 [taxonomy]
References
Chemical products information
imizoquin A
Copy SMILES
C28H30N4O9
Chemical database entries
PubCHEM
imizoquin B
Copy SMILES
C28H30N4O10
Chemical database entries
PubCHEM
imizoquin C
Copy SMILES
C28H32N4O10
Chemical database entries
PubCHEM
imizoquin D
Copy SMILES
C28H28N4O10
Chemical database entries
PubCHEM
TMC-2A
Copy SMILES
C28H34N4O9
Chemical database entries
NPAtlas
TMC-2B
Copy SMILES
C28H34N4O8
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFLA_064240
  • XP_002379984.1
 29095 - 35391 (-) nonribosomal peptide synthase, putative
copy AA seq
copy Nt seq
  • AFLA_064250
  • XP_002379985.1
 36311 - 37102 (+) phenol 2-monooxygenase, putative
copy AA seq
copy Nt seq
  • AFLA_064260
  • XP_002379986.1
 38582 - 40510 (-) oligopeptide transporter, putative
copy AA seq
copy Nt seq
  • AFLA_064270
  • XP_002379987.1
 41154 - 42314 (+) gibberellin 2-oxidase, putative
copy AA seq
copy Nt seq
  • AFLA_064280
  • XP_002379988.1
 42851 - 44016 (+) N-methyltransferase, putative
copy AA seq
copy Nt seq
  • AFLA_064290
  • XP_002379989.1
 44443 - 45186 (-) O-methyltransferase, putative
copy AA seq
copy Nt seq
  • AFLA_064300
  • XP_002379990.1
 45453 - 46964 (-) fructosyl amino acid oxidase, putative
copy AA seq
copy Nt seq
  • AFLA_064310
  • XP_002379991.1
 47408 - 47725 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFLA_064320
  • XP_002379992.1
 47758 - 50991 (+) oligopeptide transporter, putative
copy AA seq
copy Nt seq
  • AFLA_064330
  • XP_002379993.1
 51418 - 53073 (-) conserved hypothetical protein
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
AFLA_064240
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
  • Mass spectrometry
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: YQF4634PJETKNUL6ADZ4RRW4, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added missing compound details
  • Added NRP substrate specificities
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.