BGC0001625: Isofuranonaphthoquinone A biosynthetic gene cluster from Streptomyces sp. CB01883
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Location: 1 - 22,706 nt. (total: 22,706 nt).
This entry is originally from NCBI GenBank KX358898.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001625
Short description Isofuranonaphthoquinone A biosynthetic gene cluster from Streptomyces sp. CB01883
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KX358898.1
via
Compounds
  • Isofuranonaphthoquinone A
  • Isofuranonaphthoquinone B
  • Isofuranonaphthoquinone C
  • Isofuranonaphthoquinone D
  • Isofuranonaphthoquinone E
  • Isofuranonaphthoquinone F
Species Streptomyces sp. CB01883 [taxonomy]
References
Chemical products information
Isofuranonaphthoquinone A Evidence: NMR [1], Mass spectrometry [1]
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C13H8O6
Chemical database entries
NPAtlas
Isofuranonaphthoquinone B Evidence: NMR [1], Mass spectrometry [2]
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C14H10O6
Chemical database entries
NPAtlas
Isofuranonaphthoquinone C Evidence: NMR [2], Mass spectrometry [2]
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C14H10O6
Chemical database entries
NPAtlas
Isofuranonaphthoquinone D Evidence: NMR [1], Mass spectrometry [2]
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C15H12O6
Chemical database entries
NPAtlas
Isofuranonaphthoquinone E Evidence: NMR [2], Mass spectrometry [2]
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C14H10O7
Chemical database entries
NPAtlas
Isofuranonaphthoquinone F Evidence: NMR [1], Mass spectrometry [1]
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C14H10O7
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • APR73624.1
  • ifq_-1_
 1 - 765 (+) dehydrogenase
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    • APR73625.1
    • ifqA
    		 887 - 1198 (-) acyl carrier protein
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      • APR73626.1
      • ifqB
      		 1398 - 2168 (+) acyl-CoA dehydrogenase
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        • APR73627.1
        • ifqC
        		 2153 - 2887 (+) phosphopantetheinyl transferase
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          • APR73628.1
          • ifqD
          		 3228 - 4052 (+) SARP family transcriptional regulator
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            • APR73629.1
            • ifqE
            		 4138 - 4722 (+) FMN reductase
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              • APR73630.1
              • ifqF
              		 4819 - 5757 (-) esterase
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                • APR73631.1
                • ifqG
                		 5892 - 6980 (-) hypothetical protein
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                  • APR73632.1
                  • ifqH
                  		 7024 - 8223 (-) hydroxylase
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                    • APR73633.1
                    • ifqJ
                    		 8454 - 9296 (+) polyketide cyclase/aromatase
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                      • APR73634.1
                      • ifqK
                      		 9293 - 10057 (+) polyketide cyclase
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                        • APR73635.1
                        • ifqL
                        		 10047 - 10427 (+) lipocalin-like domain containing protein
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                          • APR73636.1
                          • ifqM
                          		 10548 - 11852 (-) LuxR family transcriptional regulator
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                            • APR73637.1
                            • ifqN
                            		 12104 - 13372 (+) beta-ketoacyl synthase alpha subunit
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                              • APR73638.1
                              • ifqO
                              		 13369 - 14598 (+) beta-ketoacyl synthase beta subunit
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                                • APR73639.1
                                • ifqP
                                		 14591 - 15097 (+) flavin reductase
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                                  • APR73640.1
                                  • ifqQ
                                  		 15094 - 17043 (+) Baeyer-Villiger monooxygenase
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                                    • APR73641.1
                                    • ifqR
                                    		 17083 - 18225 (+) hydroxylase
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                                      • APR73642.1
                                      • ifqS
                                      		 18236 - 19279 (+) methyltransferase
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                                        • APR73643.1
                                        • ifqT
                                        		 19276 - 19665 (+) SnoaL-like domain protein
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                                          • APR73644.1
                                          • ifqU
                                          		 19662 - 20609 (+) dehydrogenase/quinone reductase
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                                            • APR73645.1
                                            • ifq__1_
                                            		 20628 - 22706 (-) PAS sensor protein
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                                              Biosynthesis information
                                              Annotation changelog

                                              Entry version: next

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2024-04-23
                                              MIBiG v4 annotathon
                                              • (ID: OCE3JJUWNMF4OVBLYXWCZ36L)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 4

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-10-07
                                              Update chemical activity to schema version 2.11
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 3

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-09-15
                                              Updated bioactivity data
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 2

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2019-10-16
                                              Migrated from v1.4
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2018-08-06
                                              Submitted
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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