BGC0001631: kasumigamide biosynthetic gene cluster from Microcystis aeruginosa NIES-87
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Location: 1 - 26,273 nt. (total: 26,273 nt).
This entry is originally from NCBI GenBank LC160291.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001631
Short description kasumigamide biosynthetic gene cluster from Microcystis aeruginosa NIES-87
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: LC160291.1
Compounds
  • kasumigamide
Species Microcystis aeruginosa NIES-87 [taxonomy]
References
Chemical products information
kasumigamide
Copy SMILES
C40H50N8O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAW32331.1
  • ORFM1
 1 - 198 (+) transferase
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  • BAW32332.1
  • makasA
 1285 - 5337 (+) nonribosomal peptide synthetase
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  • BAW32333.1
  • makasB
 5348 - 11731 (+) nonribosomal peptide synthetase
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  • BAW32334.1
  • makasC
 11728 - 24075 (+) hybrid cis-AT polyketide synthase - nonribosomal peptide synthetase
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  • BAW32335.1
  • makasD
 24134 - 25735 (+) hydroxylase
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  • BAW32336.1
  • ORFM2
 25908 - >26237 (-) transferase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
makasA
Module ?
Specificity: phenylpyruvic acid
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
makasB
Module ?
Specificity: beta-alanine
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
Module ?
Specificity: tryptophan
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
makasC
Module ?
Specificity: arginine
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
Module ?
Specificity: R-beta-hydroxyphenylalanine / phenylalanine / D-phenylalanine
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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